HDAC8, A potential therapeutic target for the treatment of malignant peripheral nerve sheath tumors (MPNST)

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Lopez, Gonzalo ^a   Bill, Kate Lynn J ^a   Bid, Hemant Kumar ^a   Braggio, Danielle ^a   Constantino, Dylan ^a   Prudner, Bethany ^a   Zewdu, Abeba ^a   Batte, Kara ^a   Lev, Dina ^b   Pollock, Raphael E ^c  

^a OHIO STATE UNIVERSITY   (United States)

^b SHEBA MEDICAL CENTER   (Israel)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; DJ 1 PROTEIN; HIGH MOBILITY GROUP B1 PROTEIN; HISTONE DEACETYLASE 8; HISTONE DEACETYLASE 8 INHIBITOR; HISTONE DEACETYLASE INHIBITOR; PCI 34051; PCI 48012; PEROXIREDOXIN 6; PHOSPHOGLYCERATE MUTASE; PHOSPHOGLYCERATE MUTASE 1; UNCLASSIFIED DRUG; HDAC8 PROTEIN, HUMAN; HDAC8 PROTEIN, MOUSE; HISTONE DEACETYLASE; REPRESSOR PROTEIN; TUMOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG TARGETING; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALIGNANT PERIPHERAL NERVE SHEATH TUMOR; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PROTEIN ACETYLATION; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; S PHASE CELL CYCLE CHECKPOINT; TUMOR VOLUME; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DRUG SCREENING; ENZYMOLOGY; GENETICS; NEURILEMMOMA; PATHOLOGY; SCID MOUSE; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; FEMALE; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; MICE; MICE, SCID; NEOPLASM PROTEINS; NEURILEMMOMA; REPRESSOR PROTEINS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84941243512     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0133302     Document Type: Article

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