메뉴 건너뛰기




Volumn 5, Issue 3, 2015, Pages 392-404

Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 25; PROGRAMMED DEATH 1 LIGAND 1; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; CD274 PROTEIN, HUMAN; IL25 PROTEIN, HUMAN; INTERLEUKIN 17; STAT3 PROTEIN, HUMAN;

EID: 84941184783     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2015.07.013     Document Type: Article
Times cited : (64)

References (64)
  • 1
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • S. Aggarwal, and M.F. Pittenger Human mesenchymal stem cells modulate allogeneic immune cell responses Blood 105 2005 1815 1822
    • (2005) Blood , vol.105 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 2
    • 45249100402 scopus 로고    scopus 로고
    • Co-infusion of donor bone marrow with host mesenchymal stem cells treats GVHD and promotes vascularized skin allograft survival in rats
    • A.E. Aksu, E. Horibe, J. Sacks, R. Ikeguchi, J. Breitinger, M. Scozio, J. Unadkat, and M. Feili-Hariri Co-infusion of donor bone marrow with host mesenchymal stem cells treats GVHD and promotes vascularized skin allograft survival in rats Clin. Immunol. 127 2008 348 358
    • (2008) Clin. Immunol. , vol.127 , pp. 348-358
    • Aksu, A.E.1    Horibe, E.2    Sacks, J.3    Ikeguchi, R.4    Breitinger, J.5    Scozio, M.6    Unadkat, J.7    Feili-Hariri, M.8
  • 4
    • 0032939561 scopus 로고    scopus 로고
    • Evidence for a role of IL-17 in organ allograft rejection: IL-17 promotes the functional differentiation of dendritic cell progenitors
    • M.A. Antonysamy, W.C. Fanslow, F. Fu, W. Li, S. Qian, A.B. Troutt, and A.W. Thomson Evidence for a role of IL-17 in organ allograft rejection: IL-17 promotes the functional differentiation of dendritic cell progenitors J. Immunol. 162 1999 577 584
    • (1999) J. Immunol. , vol.162 , pp. 577-584
    • Antonysamy, M.A.1    Fanslow, W.C.2    Fu, F.3    Li, W.4    Qian, S.5    Troutt, A.B.6    Thomson, A.W.7
  • 8
    • 79959951133 scopus 로고    scopus 로고
    • The MSC: An injury drugstore
    • A.I. Caplan, and D. Correa The MSC: An injury drugstore Cell Stem Cell 9 2011 11 15
    • (2011) Cell Stem Cell , vol.9 , pp. 11-15
    • Caplan, A.I.1    Correa, D.2
  • 10
    • 65349153165 scopus 로고    scopus 로고
    • Inhibition of monocyte-derived inflammatory cytokines by IL-25 occurs via p38 Map kinase-dependent induction of Socs-3
    • R. Caruso, C. Stolfi, M. Sarra, A. Rizzo, M.C. Fantini, F. Pallone, T.T. MacDonald, and G. Monteleone Inhibition of monocyte-derived inflammatory cytokines by IL-25 occurs via p38 Map kinase-dependent induction of Socs-3 Blood 113 2009 3512 3519
    • (2009) Blood , vol.113 , pp. 3512-3519
    • Caruso, R.1    Stolfi, C.2    Sarra, M.3    Rizzo, A.4    Fantini, M.C.5    Pallone, F.6    MacDonald, T.T.7    Monteleone, G.8
  • 11
    • 33750563599 scopus 로고    scopus 로고
    • Placenta-derived multipotent cells exhibit immunosuppressive properties that are enhanced in the presence of interferon-gamma
    • C.J. Chang, M.L. Yen, Y.C. Chen, C.C. Chien, H.I. Huang, C.H. Bai, and B.L. Yen Placenta-derived multipotent cells exhibit immunosuppressive properties that are enhanced in the presence of interferon-gamma Stem Cells 24 2006 2466 2477
    • (2006) Stem Cells , vol.24 , pp. 2466-2477
    • Chang, C.J.1    Yen, M.L.2    Chen, Y.C.3    Chien, C.C.4    Huang, H.I.5    Bai, C.H.6    Yen, B.L.7
  • 12
    • 84941186495 scopus 로고    scopus 로고
    • Comparative proteomic analysis of proteins involved in the tumorigenic process of seminal vesicle carcinoma in transgenic mice
    • W.C. Chang, C.K. Chou, C.C. Tsou, S.H. Li, C.H. Chen, Y.X. Zhuo, W.L. Hsu, and C.H. Chen Comparative proteomic analysis of proteins involved in the tumorigenic process of seminal vesicle carcinoma in transgenic mice Int. J. Proteomics 2010 2010 726968
    • (2010) Int. J. Proteomics , vol.2010 , pp. 726968
    • Chang, W.C.1    Chou, C.K.2    Tsou, C.C.3    Li, S.H.4    Chen, C.H.5    Zhuo, Y.X.6    Hsu, W.L.7    Chen, C.H.8
  • 13
    • 79960563303 scopus 로고    scopus 로고
    • Immunomodulatory properties of human adult and fetal multipotent mesenchymal stem cells
    • P.M. Chen, M.L. Yen, K.J. Liu, H.K. Sytwu, and B.L. Yen Immunomodulatory properties of human adult and fetal multipotent mesenchymal stem cells J. Biomed. Sci. 18 2011 49 59
    • (2011) J. Biomed. Sci. , vol.18 , pp. 49-59
    • Chen, P.M.1    Yen, M.L.2    Liu, K.J.3    Sytwu, H.K.4    Yen, B.L.5
  • 15
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • M. Di Nicola, C. Carlo-Stella, M. Magni, M. Milanesi, P.D. Longoni, P. Matteucci, S. Grisanti, and A.M. Gianni Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli Blood 99 2002 3838 3843
    • (2002) Blood , vol.99 , pp. 3838-3843
    • Di Nicola, M.1    Carlo-Stella, C.2    Magni, M.3    Milanesi, M.4    Longoni, P.D.5    Matteucci, P.6    Grisanti, S.7    Gianni, A.M.8
  • 17
    • 42649115767 scopus 로고    scopus 로고
    • TH17 cells in development: An updated view of their molecular identity and genetic programming
    • C. Dong TH17 cells in development: An updated view of their molecular identity and genetic programming Nat. Rev. Immunol. 8 2008 337 348
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 337-348
    • Dong, C.1
  • 18
    • 28844483809 scopus 로고    scopus 로고
    • Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice
    • N. Eliopoulos, J. Stagg, L. Lejeune, S. Pommey, and J. Galipeau Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice Blood 106 2005 4057 4065
    • (2005) Blood , vol.106 , pp. 4057-4065
    • Eliopoulos, N.1    Stagg, J.2    Lejeune, L.3    Pommey, S.4    Galipeau, J.5
  • 19
    • 33747152561 scopus 로고    scopus 로고
    • Matrix elasticity directs stem cell lineage specification
    • A.J. Engler, S. Sen, H.L. Sweeney, and D.E. Discher Matrix elasticity directs stem cell lineage specification Cell 126 2006 677 689
    • (2006) Cell , vol.126 , pp. 677-689
    • Engler, A.J.1    Sen, S.2    Sweeney, H.L.3    Discher, D.E.4
  • 20
    • 0034079140 scopus 로고    scopus 로고
    • Mesenchymal progenitor cells in human umbilical cord blood
    • A. Erices, P. Conget, and J.J. Minguell Mesenchymal progenitor cells in human umbilical cord blood Br. J. Haematol. 109 2000 235 242
    • (2000) Br. J. Haematol. , vol.109 , pp. 235-242
    • Erices, A.1    Conget, P.2    Minguell, J.J.3
  • 22
    • 73349094069 scopus 로고    scopus 로고
    • Role of T cell TGFbeta signaling and IL-17 in allograft acceptance and fibrosis associated with chronic rejection
    • S.M. Faust, G. Lu, B.L. Marini, W. Zou, D. Gordon, Y. Iwakura, Y. Laouar, and D.K. Bishop Role of T cell TGFbeta signaling and IL-17 in allograft acceptance and fibrosis associated with chronic rejection J. Immunol. 183 2009 7297 7306
    • (2009) J. Immunol. , vol.183 , pp. 7297-7306
    • Faust, S.M.1    Lu, G.2    Marini, B.L.3    Zou, W.4    Gordon, D.5    Iwakura, Y.6    Laouar, Y.7    Bishop, D.K.8
  • 23
    • 0017103248 scopus 로고
    • Precursor cells of mechanocytes
    • A.J. Friedenstein Precursor cells of mechanocytes Int. Rev. Cytol. 47 1976 327 359
    • (1976) Int. Rev. Cytol. , vol.47 , pp. 327-359
    • Friedenstein, A.J.1
  • 24
    • 79954536472 scopus 로고    scopus 로고
    • IL-25 causes apoptosis of IL-25R-expressing breast cancer cells without toxicity to nonmalignant cells
    • S. Furuta, Y.M. Jeng, L. Zhou, L. Huang, I. Kuhn, M.J. Bissell, and W.H. Lee IL-25 causes apoptosis of IL-25R-expressing breast cancer cells without toxicity to nonmalignant cells Sci. Transl. Med. 3 2011 78ra31
    • (2011) Sci. Transl. Med. , vol.3 , pp. 78ra31
    • Furuta, S.1    Jeng, Y.M.2    Zhou, L.3    Huang, L.4    Kuhn, I.5    Bissell, M.J.6    Lee, W.H.7
  • 25
    • 84856630796 scopus 로고    scopus 로고
    • The immunomodulatory capacity of mesenchymal stem cells
    • A. Gebler, O. Zabel, and B. Seliger The immunomodulatory capacity of mesenchymal stem cells Trends Mol. Med. 18 2012 128 134
    • (2012) Trends Mol. Med. , vol.18 , pp. 128-134
    • Gebler, A.1    Zabel, O.2    Seliger, B.3
  • 26
    • 77956215701 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit human Th17 cell differentiation and function and induce a T regulatory cell phenotype
    • S. Ghannam, J. Pène, G. Moquet-Torcy, C. Jorgensen, and H. Yssel Mesenchymal stem cells inhibit human Th17 cell differentiation and function and induce a T regulatory cell phenotype J. Immunol. 185 2010 302 312
    • (2010) J. Immunol. , vol.185 , pp. 302-312
    • Ghannam, S.1    Pène, J.2    Moquet-Torcy, G.3    Jorgensen, C.4    Yssel, H.5
  • 27
    • 33847617021 scopus 로고    scopus 로고
    • From the laboratory bench to the patient's bedside: An update on clinical trials with mesenchymal stem cells
    • A. Giordano, U. Galderisi, and I.R. Marino From the laboratory bench to the patient's bedside: An update on clinical trials with mesenchymal stem cells J. Cell. Physiol. 211 2007 27 35
    • (2007) J. Cell. Physiol. , vol.211 , pp. 27-35
    • Giordano, A.1    Galderisi, U.2    Marino, I.R.3
  • 28
    • 65249161683 scopus 로고    scopus 로고
    • Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells
    • M.A. González, E. Gonzalez-Rey, L. Rico, D. Büscher, and M. Delgado Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells Arthritis Rheum. 60 2009 1006 1019
    • (2009) Arthritis Rheum. , vol.60 , pp. 1006-1019
    • González, M.A.1    Gonzalez-Rey, E.2    Rico, L.3    Büscher, D.4    Delgado, M.5
  • 29
    • 84870887067 scopus 로고    scopus 로고
    • Comparison of allogeneic vs autologous bone marrow-derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic cardiomyopathy: The POSEIDON randomized trial
    • J.M. Hare, J.E. Fishman, G. Gerstenblith, D.L. DiFede Velazquez, J.P. Zambrano, V.Y. Suncion, M. Tracy, E. Ghersin, P.V. Johnston, J.A. Brinker, and et al. Comparison of allogeneic vs autologous bone marrow-derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic cardiomyopathy: The POSEIDON randomized trial JAMA 308 2012 2369 2379
    • (2012) JAMA , vol.308 , pp. 2369-2379
    • Hare, J.M.1    Fishman, J.E.2    Gerstenblith, G.3    DiFede Velazquez, D.L.4    Zambrano, J.P.5    Suncion, V.Y.6    Tracy, M.7    Ghersin, E.8    Johnston, P.V.9    Brinker, J.A.10
  • 31
    • 79951743212 scopus 로고    scopus 로고
    • Functional specialization of interleukin-17 family members
    • Y. Iwakura, H. Ishigame, S. Saijo, and S. Nakae Functional specialization of interleukin-17 family members Immunity 34 2011 149 162
    • (2011) Immunity , vol.34 , pp. 149-162
    • Iwakura, Y.1    Ishigame, H.2    Saijo, S.3    Nakae, S.4
  • 33
    • 0036785392 scopus 로고    scopus 로고
    • Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production
    • M.R. Kim, R. Manoukian, R. Yeh, S.M. Silbiger, D.M. Danilenko, S. Scully, J. Sun, M.L. DeRose, M. Stolina, D. Chang, and et al. Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production Blood 100 2002 2330 2340
    • (2002) Blood , vol.100 , pp. 2330-2340
    • Kim, M.R.1    Manoukian, R.2    Yeh, R.3    Silbiger, S.M.4    Danilenko, D.M.5    Scully, S.6    Sun, J.7    DeRose, M.L.8    Stolina, M.9    Chang, D.10
  • 34
    • 84883898505 scopus 로고    scopus 로고
    • Mesenchymal stem cells for the treatment and prevention of graft-versus-host disease: Experiments and practice
    • N. Kim, K.I. Im, J.Y. Lim, E.J. Jeon, Y.S. Nam, E.J. Kim, and S.G. Cho Mesenchymal stem cells for the treatment and prevention of graft-versus-host disease: Experiments and practice Ann. Hematol. 92 2013 1295 1308
    • (2013) Ann. Hematol. , vol.92 , pp. 1295-1308
    • Kim, N.1    Im, K.I.2    Lim, J.Y.3    Jeon, E.J.4    Nam, Y.S.5    Kim, E.J.6    Cho, S.G.7
  • 37
    • 84860238652 scopus 로고    scopus 로고
    • Multipotent mesenchymal stromal cells and the innate immune system
    • K. Le Blanc, and D. Mougiakakos Multipotent mesenchymal stromal cells and the innate immune system Nat. Rev. Immunol. 12 2012 383 396
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 383-396
    • Le Blanc, K.1    Mougiakakos, D.2
  • 38
    • 43049103438 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: A phase II study
    • K. Le Blanc, F. Frassoni, L. Ball, F. Locatelli, H. Roelofs, I. Lewis, E. Lanino, B. Sundberg, M.E. Bernardo, M. Remberger, et al. Developmental Committee of the European Group for Blood and Marrow Transplantation Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: A phase II study Lancet 371 2008 1579 1586
    • (2008) Lancet , vol.371 , pp. 1579-1586
    • Le Blanc, K.1    Frassoni, F.2    Ball, L.3    Locatelli, F.4    Roelofs, H.5    Lewis, I.6    Lanino, E.7    Sundberg, B.8    Bernardo, M.E.9    Remberger, M.10
  • 42
    • 17844391825 scopus 로고    scopus 로고
    • Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regulatory/suppressive phenotype
    • R. Maccario, M. Podestà, A. Moretta, A. Cometa, P. Comoli, D. Montagna, L. Daudt, A. Ibatici, G. Piaggio, S. Pozzi, and et al. Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regulatory/suppressive phenotype Haematologica 90 2005 516 525
    • (2005) Haematologica , vol.90 , pp. 516-525
    • Maccario, R.1    Podestà, M.2    Moretta, A.3    Cometa, A.4    Comoli, P.5    Montagna, D.6    Daudt, L.7    Ibatici, A.8    Piaggio, G.9    Pozzi, S.10
  • 43
    • 84866934694 scopus 로고    scopus 로고
    • Targeting IL-17 and TH17 cells in chronic inflammation
    • P. Miossec, and J.K. Kolls Targeting IL-17 and TH17 cells in chronic inflammation Nat. Rev. Drug Discov. 11 2012 763 776
    • (2012) Nat. Rev. Drug Discov. , vol.11 , pp. 763-776
    • Miossec, P.1    Kolls, J.K.2
  • 44
    • 78649704149 scopus 로고    scopus 로고
    • Interleukin-25: A two-edged sword in the control of immune-inflammatory responses
    • G. Monteleone, F. Pallone, and T.T. Macdonald Interleukin-25: A two-edged sword in the control of immune-inflammatory responses Cytokine Growth Factor Rev. 21 2010 471 475
    • (2010) Cytokine Growth Factor Rev. , vol.21 , pp. 471-475
    • Monteleone, G.1    Pallone, F.2    MacDonald, T.T.3
  • 47
    • 38349053355 scopus 로고    scopus 로고
    • Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cells
    • Z. Selmani, A. Naji, I. Zidi, B. Favier, E. Gaiffe, L. Obert, C. Borg, P. Saas, P. Tiberghien, N. Rouas-Freiss, and et al. Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cells Stem Cells 26 2008 212 222
    • (2008) Stem Cells , vol.26 , pp. 212-222
    • Selmani, Z.1    Naji, A.2    Zidi, I.3    Favier, B.4    Gaiffe, E.5    Obert, L.6    Borg, C.7    Saas, P.8    Tiberghien, P.9    Rouas-Freiss, N.10
  • 48
    • 84879616587 scopus 로고    scopus 로고
    • Differential involvement of Th1 and Th17 in pathogenic autoimmune processes triggered by different TLR ligands
    • G. Shi, B.P. Vistica, L.F. Nugent, C. Tan, E.F. Wawrousek, D.M. Klinman, and I. Gery Differential involvement of Th1 and Th17 in pathogenic autoimmune processes triggered by different TLR ligands J. Immunol. 191 2013 415 423
    • (2013) J. Immunol. , vol.191 , pp. 415-423
    • Shi, G.1    Vistica, B.P.2    Nugent, L.F.3    Tan, C.4    Wawrousek, E.F.5    Klinman, D.M.6    Gery, I.7
  • 49
    • 33644799418 scopus 로고    scopus 로고
    • Interferon-gamma-stimulated marrow stromal cells: A new type of nonhematopoietic antigen-presenting cell
    • J. Stagg, S. Pommey, N. Eliopoulos, and J. Galipeau Interferon-gamma-stimulated marrow stromal cells: A new type of nonhematopoietic antigen-presenting cell Blood 107 2006 2570 2577
    • (2006) Blood , vol.107 , pp. 2570-2577
    • Stagg, J.1    Pommey, S.2    Eliopoulos, N.3    Galipeau, J.4
  • 50
    • 78851470077 scopus 로고    scopus 로고
    • The STATus of PD-L1 (B7-H1) on tolerogenic APCs
    • T.L. Sumpter, and A.W. Thomson The STATus of PD-L1 (B7-H1) on tolerogenic APCs Eur. J. Immunol. 41 2011 286 290
    • (2011) Eur. J. Immunol. , vol.41 , pp. 286-290
    • Sumpter, T.L.1    Thomson, A.W.2
  • 51
    • 67649604299 scopus 로고    scopus 로고
    • Mesenchymal stem cell transplantation reverses multiorgan dysfunction in systemic lupus erythematosus mice and humans
    • L. Sun, K. Akiyama, H. Zhang, T. Yamaza, Y. Hou, S. Zhao, T. Xu, A. Le, and S. Shi Mesenchymal stem cell transplantation reverses multiorgan dysfunction in systemic lupus erythematosus mice and humans Stem Cells 27 2009 1421 1432
    • (2009) Stem Cells , vol.27 , pp. 1421-1432
    • Sun, L.1    Akiyama, K.2    Zhang, H.3    Yamaza, T.4    Hou, Y.5    Zhao, S.6    Xu, T.7    Le, A.8    Shi, S.9
  • 52
    • 84863338204 scopus 로고    scopus 로고
    • Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: A randomized controlled trial
    • J. Tan, W. Wu, X. Xu, L. Liao, F. Zheng, S. Messinger, X. Sun, J. Chen, S. Yang, J. Cai, and et al. Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: A randomized controlled trial JAMA 307 2012 1169 1177
    • (2012) JAMA , vol.307 , pp. 1169-1177
    • Tan, J.1    Wu, W.2    Xu, X.3    Liao, L.4    Zheng, F.5    Messinger, S.6    Sun, X.7    Chen, J.8    Yang, S.9    Cai, J.10
  • 54
    • 77952398298 scopus 로고    scopus 로고
    • Phagocytosis of apoptotic cells modulates mesenchymal stem cells osteogenic differentiation to enhance IL-17 and RANKL expression on CD4+ T cells
    • G.H. Tso, H.K. Law, W. Tu, G.C. Chan, and Y.L. Lau Phagocytosis of apoptotic cells modulates mesenchymal stem cells osteogenic differentiation to enhance IL-17 and RANKL expression on CD4+ T cells Stem Cells 28 2010 939 954
    • (2010) Stem Cells , vol.28 , pp. 939-954
    • Tso, G.H.1    Law, H.K.2    Tu, W.3    Chan, G.C.4    Lau, Y.L.5
  • 55
  • 56
    • 72949106340 scopus 로고    scopus 로고
    • Interplay between the TH17 and TReg cell lineages: A (co-)evolutionary perspective
    • C.T. Weaver, and R.D. Hatton Interplay between the TH17 and TReg cell lineages: A (co-)evolutionary perspective Nat. Rev. Immunol. 9 2009 883 889
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 883-889
    • Weaver, C.T.1    Hatton, R.D.2
  • 58
    • 84867810334 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cell treatment alleviates experimental and clinical Sjögren syndrome
    • J. Xu, D. Wang, D. Liu, Z. Fan, H. Zhang, O. Liu, G. Ding, R. Gao, C. Zhang, Y. Ding, and et al. Allogeneic mesenchymal stem cell treatment alleviates experimental and clinical Sjögren syndrome Blood 120 2012 3142 3151
    • (2012) Blood , vol.120 , pp. 3142-3151
    • Xu, J.1    Wang, D.2    Liu, D.3    Fan, Z.4    Zhang, H.5    Liu, O.6    Ding, G.7    Gao, R.8    Zhang, C.9    Ding, Y.10
  • 60
    • 84881337812 scopus 로고    scopus 로고
    • Multipotent human mesenchymal stromal cells mediate expansion of myeloid-derived suppressor cells via hepatocyte growth factor/c-met and STAT3
    • B.L. Yen, M.L. Yen, P.J. Hsu, K.J. Liu, C.J. Wang, C.H. Bai, and H.K. Sytwu Multipotent human mesenchymal stromal cells mediate expansion of myeloid-derived suppressor cells via hepatocyte growth factor/c-met and STAT3 Stem Cell Reports 1 2013 139 151
    • (2013) Stem Cell Reports , vol.1 , pp. 139-151
    • Yen, B.L.1    Yen, M.L.2    Hsu, P.J.3    Liu, K.J.4    Wang, C.J.5    Bai, C.H.6    Sytwu, H.K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.