Chronic hypertension leads to neurodegeneration in the TgSwDI mouse model of Alzheimer's disease

Hypertension

Volumn 66, Issue 1, 2015, Pages 175-182

  Kruyer, Anna ^a   Soplop, Nadine ^a   Strickland, Sidney ^a   Norris, Erin H ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

blood brain barrier; cerebral amyloid angiopathy; hypertension

Indexed keywords

ALBUMIN; AMYLOID BETA PROTEIN; COLLAGEN TYPE 4; N(G) NITROARGININE METHYL ESTER; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; AMYLOID PRECURSOR PROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BASEMENT MEMBRANE; BLOOD BRAIN BARRIER; BLOOD COMPONENT; CELL DEATH; CELL LOSS; COGNITIVE DEFECT; CONTROLLED STUDY; DENTATE GYRUS; ELECTRON MICROSCOPY; FEMALE; HYPERTENSION; IMMUNOELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; LOCOMOTION; MALE; MICROGLIA; MICROVASCULATURE; MOUSE; NERVE CELL; NERVE DEGENERATION; NONHUMAN; PERICYTE; PRIORITY JOURNAL; SUBICULUM; TIGHT JUNCTION; ANIMAL; BRAIN; C57BL MOUSE; CEREBRAL AMYLOID ANGIOPATHY; CHEMICALLY INDUCED; CHEMISTRY; CHRONIC DISEASE; COMPLICATION; DEMENTIA, VASCULAR; DISEASE MODEL; GENETICS; HIPPOCAMPUS; HUMAN; MAZE TEST; MUTATION; ONSET AGE; PATHOLOGY; PATHOPHYSIOLOGY; TRANSGENIC MOUSE; VASCULARIZATION; VASCULITIS;

AGE OF ONSET; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CEREBRAL AMYLOID ANGIOPATHY; CHRONIC DISEASE; DEMENTIA, VASCULAR; DISEASE MODELS, ANIMAL; FEMALE; HIPPOCAMPUS; HUMANS; HYPERTENSION; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROVESSELS; MUTATION; NERVE DEGENERATION; NG-NITROARGININE METHYL ESTER; PERICYTES; VASCULITIS;

EID: 84941050887     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.115.05524     Document Type: Article

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