Oxidized LDL-bound CD36 recruits an Na+/K+-ATPase-Lyn complex in macrophages that promotes atherosclerosis

Science Signaling

Volumn 8, Issue 393, 2015, Pages

  Chen, Yiliang ^a   Kennedy, David J ^b   Ramakrishnan, Devi Prasadh ^a,c   Yang, Moua ^a,d   Huang, Wenxin ^a   Li, Zhichuan ^b   Xie, Zijian ^b   Chadwick, Alexandra C ^d   Sahoo, Daisy ^d   Silverstein, Roy L ^a,d  

^a BLOOD RESEARCH INSTITUTE   (United States)

^b MEDICAL COLLEGE OF OHIO   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

^d MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CD36 ANTIGEN; CHOLESTEROL; FOCAL ADHESION KINASE; MYOSIN; OXIDIZED LOW DENSITY LIPOPROTEIN; PROTEIN KINASE LYN; SOLUTE CARRIER ORGANIC ANION TRANSPORTER 1A1; TRIACYLGLYCEROL; ATP1A1 PROTEIN, MOUSE; LOW DENSITY LIPOPROTEIN; LYN PROTEIN-TYROSINE KINASE; PROTEIN TYROSINE KINASE;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; BIOACCUMULATION; CELL ISOLATION; CELL MEMBRANE; CLINICAL ASSESSMENT; CONTROLLED STUDY; DIETARY INTAKE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME INHIBITION; FOAM CELL; GENE DELETION; HETEROZYGOTE; MACROPHAGE; MACROPHAGE MIGRATION; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY;

ANIMALS; ANTIGENS, CD36; ATHEROSCLEROSIS; LIPOPROTEINS, LDL; MACROPHAGES; MICE; MICE, KNOCKOUT; SODIUM-POTASSIUM-EXCHANGING ATPASE; SRC-FAMILY KINASES;

EID: 84941034207     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.aaa9623     Document Type: Article

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