Brain invasion by mouse hepatitis virus depends on impairment of tight junctions and beta interferon production in brain microvascular endothelial cells

Journal of Virology

Volumn 89, Issue 19, 2015, Pages 9896-9908

  Bleau, Christian ^a   Filliol, Aveline ^b   Samson, Michel ^b   Lamontagne, Lucie ^a  

^a UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^b UNIVERSITÉ DE RENNES 1   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; CLAUDIN 5; OCCLUDIN; PROTEIN ZO1; TOLL LIKE RECEPTOR 2; VASCULAR ENDOTHELIAL CADHERIN; PRIMER DNA; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN INFECTION; CAPILLARY ENDOTHELIAL CELL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CORONAVIRUS INFECTION; CYTOKINE PRODUCTION; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MURINE HEPATITIS VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TIGHT JUNCTION; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; VIRAL TROPISM; VIRUS REPLICATION; VIRUS STRAIN; ANIMAL; BRAIN; C57BL MOUSE; CELL LINE; CYTOLOGY; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; IMMUNOHISTOCHEMISTRY; IMPEDANCE; LIVER; METABOLISM; MICROVASCULATURE; PATHOGENICITY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; VIROLOGY; VIRULENCE;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CELL LINE; DNA PRIMERS; ELECTRIC IMPEDANCE; ENDOTHELIAL CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOHISTOCHEMISTRY; INTERFERON-BETA; LIVER; MICE; MICE, INBRED C57BL; MICROVESSELS; MURINE HEPATITIS VIRUS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; TIGHT JUNCTIONS; VIRAL TROPISM; VIRULENCE;

EID: 84941000877     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01501-15     Document Type: Article

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