Macrophage interleukin-6 and tumour necrosis factor-α are induced by coronavirus fixation to Toll-like receptor 2/heparan sulphate receptors but not carcinoembryonic cell adhesion antigen 1a

Immunology

Volumn 128, Issue 1 PART 2, 2009, Pages

  Jacques, Alexandre ^a   Bleau, Christian ^a   Turbide, Claire ^b   Beauchemin, Nicole ^b   Lamontagne, Lucie ^a  

^a UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Carcinoembryonic cell adhesion antigen 1a (CEACAM1a); Heparan sulphate; Inflammation; Mouse hepatitis virus; Toll like receptor 2

Indexed keywords

CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1A; HEPARAN SULFATE RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE P38; PATTERN RECOGNITION RECEPTOR; PROTEIN SPIKE; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HISTOPATHOLOGY; INFLAMMATION; LIVER; MOUSE; MURINE HEPATITIS CORONAVIRUS; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; VIRUS INFECTION;

ANIMALS; BUTADIENES; CARCINOEMBRYONIC ANTIGEN; CELL LINE; CORONAVIRUS INFECTIONS; ENZYME INHIBITORS; FIBROBLASTS; HEPARITIN SULFATE; HEPATITIS, ANIMAL; IMIDAZOLES; INTERLEUKIN-6; LIVER; MACROPHAGES, PERITONEAL; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; MURINE HEPATITIS VIRUS; NITRILES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PYRIDINES; TOLL-LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR-ALPHA; VIRAL ENVELOPE PROTEINS; VIRUS REPLICATION;

EID: 68249139918     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2008.02946.x     Document Type: Article

References (55)

1. Kelly J, Beddall MH, Yu D, Iyer SR, Marsh JW, Wu Y. Human macrophages support persistent transcription from unintegrated HIV-1 DNA. Virology 2008 372 : 300 12.
2. Crotta S, Stilla A, Wack A et al. Inhibition of natural killer cells through engagement of CD81 by the major hepatitis C virus envelope protein. J Exp Med 2002 195 : 35 41.
3. Paludan SR, Melchjorsen J, Malmgaard L, Mogensen SC. Expression of genes for cytokines and cytokine-related functions in leukocytes infected with Herpes simplex virus: comparison between resistant and susceptible mouse strains. Eur Cytokine Netw 2002 13 : 306 16.
4. Medzhitov R, Janeway CA Jr. Decoding the patterns of self and nonself by the innate immune system. Science 2002 296 : 298 300.
5. Unterholzner L, Bowie AG. The interplay between viruses and innate immune signaling: recent insights and therapeutic opportunities. Biochem Pharmacol 2008 75 : 589 602.
6. Wang W, Ye L, Ye L et al. Up-regulation of IL-6 and TNF-alpha induced by SARS-coronavirus spike protein in murine macrophages via NF-kappaB pathway. Virus Res 2007 128 : 1 8.
7. Tseng CT, Perrone LA, Zhu H, Makino S, Peters CJ. Severe acute respiratory syndrome and the innate immune responses: modulation of effector cell function without productive infection. J Immunol 2005 174 : 7977 85.
8. Takano T, Hohdatsu T, Toda A, Tanabe M, Koyama H. TNF-alpha, produced by feline infectious peritonitis virus (FIPV)-infected macrophages, upregulates expression of type II FIPV receptor feline aminopeptidase N in feline macrophages. Virology 2007 364 : 64 72.
9. D'Addario M, Ahmad A, Morgan A, Menezes J. Binding of the Epstein-Barr virus major envelope glycoprotein gp350 results in the upregulation of the TNF-alpha gene expression in monocytic cells via NF-kappaB involving PKC, PI3-K and tyrosine kinases. J Mol Biol 2000 298 : 765 78.
10. Levy-Leblond E, Oth O, Dupuy JM. Genetic study of mouse sensivity to MHV3 infection: influence of the H-2 complex. J Immunol 1979 112 : 1359 62.
11. Le Prevost C, Levy-Leblond E, Virelizier JL, Dupuy JM. Immunopathology of mouse hepatitis virus type 3 infection. I. Role of humoral and cell-mediated immunity in resistance mechanism. J Immunol 1975 114 : 221 5.
12. Dupuy JM, Levy-Leblond E, Le Prevost C. Immunopathology of mouse hepatitis virus type 3 infection. II. Effect of immunosuppression in resistant mice. J Immunol 1975 114 : 226 30.
13. Martin JP, Chen W, Koehren F, Pereira CA. The virulence of mouse hepatitis virus 3, as evidence by permissivity of cultured hepatic cells toward escaped mutants. Res Virol 1994 145 : 297 302.
14. Jacques A, Bleau C, Martin JP, Lamontagne L. Intrahepatic endothelial and Kupffer cells involved in immunosuppressive cytokines and natural killer (NK)/NK-T cell disorders in viral acute hepatitis. Clin Exp Immunol 2008 152 : 298 310.
15. Beauchemin N, Draber P, Dveksler G et al. Redefined nomenclature for members of the carcinoembryonic antigen family. Exp Cell Res 1999 252 : 243 9.
16. Dveksler GS, Pensiero MN, Cardellichio CB, Williams RK, Jiang GS, Holmes KV, Dieffenbach CW. Cloning of the mouse hepatitis virus (MHV) receptor: expression in human and hamster cell lines confers susceptibility to MHV. J Virol 1991 65 : 6881 91.
17. Leusch HG, Drzeniek Z, Markos-Pusztai Z, Wagener C. Binding of Escherichia coli and Salmonella strains to members of the carcinoembryonic antigen family: differential binding inhibition by aromatic -glycosides of mannose. Infect Immun 1991 59 : 2051 7.
18. Hemmila E, Turbide C, Olson M, Jothy S, Holmes KV, Beauchemin N. Ceacam1a-/- mice are completely resistant to infection by murine coronavirus mouse hepatitis virus A59. J Virol 2004 78 : 10156 65.
19. Edmiston KH, Gangopadhyay A, Shoji Y, Nachman AP, Thomas P, Jessup JM. In vivo induction of murine cytokine production by carcinoembryonic antigen. Cancer Res 1997 57 : 4432 6.
20. Gangopadhyay A, Lazure DA, Thomas P. Carcinoembryonic antigen induces signal transduction in Kupffer cells. Cancer Lett 1997 118 : 1 6.
21. Budt M, Cichocka I, Reutter W, Lucka L. Clustering-induced signaling of CEACAM1 in PC12 cells. Biol Chem 2002 383 : 803 12.
22. McGilvray ID, Lu Z, Wei AC, Dackiw AP, Marshall JC, Kapus A, Levy G, Rotstein OD. Murine hepatitis virus strain 3 induces the macrophage prothrombinase fgl-2 through p38 mitogen-activated protein kinase activation. J Biol Chem 1998 273 : 32222 9.
23. de Haan CAM, Li Z, te Lintelo E, Bosch BJ, Hijema BJ, Rottier JM. Murine coronavirus with an extended host range uses heparan sulphate as an entry receptor. J Virol 2005 79 : 14451 6.
24. Watanabe R, Sawicki SG, Taguchi F. Heparan sulfate is a binding molecule but not a receptor for CEACAM1-independent infection of murine coronavirus. Virology 2007 366 : 16 22.
25. Cooper A, Tal G, Lider O, Shaul Y. Cytokine induction by the hepatitis B virus capsid in macrophages is facilitated by membrane heparan sulfate and involves TLR2. J Immunol 2005 175 : 3165 76.
26. Dolganiuc A, Oak S, Kodys K, Golenbock DT, Finberg RW, Kurt-Jones E, Szabo G. Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation. Gastroenterology 2004 127 : 1513 24.
27. Kurt-Jones EA, Chan M, Zhou S et al. Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis. Proc Natl Acad Sci USA 2004 101 : 1315 20.
28. Compton T, Kurt-Jones EA, Boehme KW, Belko J, Latz E, Golenbock DT, Finberg RW. Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2. J Virol 2003 77 : 4588 96.
29. Kawai T, Akira S. Pathogen recognition with Toll-like receptors. Curr Opin Immunol 2005 17 : 338 44.
30. Oyanagi Y, Takahashi T, Matsui S et al. Enhanced expression of interleukin-6 in chronic hepatitis C. Liver 1999 19 : 464 72.
31. Vidigal P, Germer JJ, Zein NN. Polymorphisms in the interleukin-10, tumor necrosis factor-alpha, and transforming growth factor-beta1 genes in chronic hepatitis C patients treated with interferon and ribavirin. J Hepatol 2002 36 : 271 7.
32. Lio D, Caruso C, Di Stefano R et al. IL-10 and TNF-alpha polymorphisms and the recovery from HCV infection. Hum Immunol 2003 64 : 674 80.
33. Riordan SM, Skinner NA, Kurtovic J, Locarnini S, McIver CJ, Williams R, Visvanathan K. Toll-like receptor expression in chronic hepatitis C: correlation with pro-inflammatory cytokine levels and liver injury. Inflamm Res 2006 55 : 279 85.
34. Leung N, Turbide C, Olson M, Marcus V, Jothy S, Beauchemin N. Deletion of the carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1) gene contributes to colon tumor progression in a murine model of carcinogenesis. Oncogene 2006 25 : 5527 36.
35. Dupuy JM, Rodrigue D. Heterogeneity in evolutive patterns of inbred mice infected with a cloned substrain of mouse hepatitis virus type 3. Intervirology 1981 16 : 114 7.
36. Watanabe H, Ohtsuka K, Kimura M et al. Details of an isolation method for hepatic lymphocytes in mice. J Immunol 1992 146 : 145 54.
37. Lamontagne L, Massicotte E, Page C. Mouse hepatitis viral infection induces an extrathymic differentiation of the specific intrahepatic alpha beta-TCRintermediate LFA-1high T-cell population. Immunology 1997 90 : 402 10.
38. Pathak MK, Yi T. Sodium stibogluconate is a potent inhibitor of protein tyrosine phosphatases and augments cytokine responses in hemopoietic cell lines. J Immunol 2001 167 : 3391 7.
39. Nunez A, Gomez-Villamandos JC, Sanchez-Cordon PJ, Fernandez de Marco M, Pedrera M, Salguero FJ, Carrasco L. Expression of proinflammatory cytokines by hepatic macrophages in acute classical swine fever. J Comp Pathol 2005 133 : 23 32. (Pubitemid 40744454)
40. Xie GQ, Jiang JX, Chen YH, Liu DW, Zhu PF, Wang ZG. Induction of acute hepatic injury by endotoxin in mice. Hepatobiliary Pancreat Dis Int 2002 1 : 558 64.
41. Barthold SW, Smith AL. Response of genetically susceptible and resistant mice to intranasal inoculation with mouse hepatitis virus JHM. Virus Res 1987 7 : 225 39.
42. Kammerer R, Stober D, Singer BB, Obrink B, Reimann J. Carcinoembryonic antigen-related cell adhesion molecule 1 on murine dendritic cells is a potent regulator of T cell stimulation. J Immunol 2001 166 : 6537 44.
43. Stern N, Markel G, Arnon TI, Gruda R, Wong H, Gray-Owen SD, Mandelboim O. Carcinoembryonic antigen (CEA) inhibits NK killing via interaction with CEA-related cell adhesion molecule 1. J Immunol 2005 174 : 6692 701.
44. de Haan CAM, te Lintelo E, Li Z, Raaben M, Wurdinger T, Bosch BJ, Rottier PJM. Cooperative involvement of the S1 and S2 subunits of the murine coronavirus spike protein in receptor binding and extended host range. J Virol 2006 80 : 10909 18.
45. Ghosh S, May MJ, Kopp EB. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol 1998 16 : 225 60.
46. Zelus BD, Schickli JH, Blau DM, Weiss SR, Holmes KV. Conformational changes in the spike glycoprotein of murine coronavirus are induced at 37 degrees C either by soluble murine CEACAM1 receptors or by pH 8. J Virol 2003 77 : 830 40.
47. Banerjee S, Narayanan K, Mizutani T, Makino S. Murine coronavirus replication-induced p38 mitogen-activated protein kinase activation promotes interleukin-6 production and virus replication in cultured cells. J Virol 2002 76 : 5937 48.
48. Muenzner P, Billker O, Meyer TF, Naumann M. Nuclear factor-kappa B directs carcinoembryonic antigen-related cellular adhesion molecule 1 receptor expression in Neisseria gonorrhoeae-infected epithelial cells. J Biol Chem 2002 277 : 7438 46.
49. Singer BB, Scheffrahn I, Heymann R, Sigmundsson K, Kammerer R, Obrink B. Carcinoembryonic antigen-related cell adhesion molecule 1 expression and signaling in human, mouse, and rat leukocytes: evidence for replacement of the short cytoplasmic domain isoform by glycosylphosphatidylinositol-linked proteins in human leukocytes. J Immunol 2002 168 : 5139 46.
50. Scheffrahn I, Singer BB, Sigmundsson K, Lucka L, Obrink B. Control of density-dependent, cell state-specific signal transduction by the cell adhesion molecule CEACAM1, and its influence on cell cycle regulation. Exp Cell Res 2005 307 : 427 35.
51. Thobe BM, Frink M, Hildebrand F, Schwacha MG, Hubbard WJ, Choudhry MA, Chaudry IH. The role of MAPK in Kupffer cell Toll-like receptor (TLR) 2-, TLR4-, and TLR9-mediated signaling following trauma-hemorrhage. J Cell Physiol 2007 210 : 667 75.
52. Wong CK, Cheung PF, Ip WK, Lam CW. Intracellular signaling mechanisms regulating Toll-like receptor-mediated activation of eosinophils. Am J Respir Cell Mol Biol 2007 37 : 85 96.
53. Okabayashi T, Kariwa H, Yokota S et al. Cytokine regulation in SARS coronavirus infection compared to other respiratory virus infections. J Med Virol 2006 78 : 417 24.
54. Cervantes-Barragan L, Zust R, Weber F et al. Control of coronavirus infection through plasmacytoid-cell-derived type 1 interferon. Blood 2008 109 : 1131 7.
55. Zhou H, Perlman S. Mouse hepatitis virus does not induce beta interferon synthesis and does not inhibit its induction by double-stranded RNA. J Virol 2007 81 : 568 74.