-
1
-
-
0034091578
-
Reduction of globotriaosylceramide in Fabry disease mice by substrate deprivation
-
A. Abe, S. Gregory, L. Lee, P.D. Killen, R.O. Brady, A. Kulkarni, and J.A. Shayman Reduction of globotriaosylceramide in Fabry disease mice by substrate deprivation J. Clin. Invest. 105 2000 1563 1571
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1563-1571
-
-
Abe, A.1
Gregory, S.2
Lee, L.3
Killen, P.D.4
Brady, R.O.5
Kulkarni, A.6
Shayman, J.A.7
-
2
-
-
84940971833
-
Recent advances in the diagnosis and treatment of niemann-pick disease type C in children: A guide to early diagnosis for the general pediatrician
-
H. Alobaidy Recent advances in the diagnosis and treatment of niemann-pick disease type C in children: a guide to early diagnosis for the general pediatrician Int. J. Pediatr. 2015 2015 816593
-
(2015)
Int. J. Pediatr.
, vol.2015
, pp. 816593
-
-
Alobaidy, H.1
-
3
-
-
84880824276
-
Action of Shiga toxin type-2 and subtilase cytotoxin on human microvascular endothelial cells
-
M.M. Amaral, F. Sacerdoti, C. Jancic, H.A. Repetto, A.W. Paton, J.C. Paton, and C. Ibarra Action of shiga toxin type-2 and subtilase cytotoxin on human microvascular endothelial cells PLoS One 8 2013 e70431
-
(2013)
PLoS One
, vol.8
, pp. e70431
-
-
Amaral, M.M.1
Sacerdoti, F.2
Jancic, C.3
Repetto, H.A.4
Paton, A.W.5
Paton, J.C.6
Ibarra, C.7
-
4
-
-
0033005150
-
Differential effects of glycolipid biosynthesis inhibitors on ceramide-induced cell death in neuroblastoma cells
-
E. Bieberich, B. Freischutz, M. Suzuki, and R.K. Yu Differential effects of glycolipid biosynthesis inhibitors on ceramide-induced cell death in neuroblastoma cells J. Neurochem. 72 1999 1040 1049
-
(1999)
J. Neurochem.
, vol.72
, pp. 1040-1049
-
-
Bieberich, E.1
Freischutz, B.2
Suzuki, M.3
Yu, R.K.4
-
5
-
-
33845261493
-
A rapid method of total lipid extraction and purification
-
E.G. Bligh, and W.J. Dyer A rapid method of total lipid extraction and purification Can. J. Biochem. Physiol. 37 1959 911 917
-
(1959)
Can. J. Biochem. Physiol.
, vol.37
, pp. 911-917
-
-
Bligh, E.G.1
Dyer, W.J.2
-
6
-
-
32244445841
-
Cytotoxic effect of Shiga toxin-2 holotoxin and its B subunit on human renal tubular epithelial cells
-
V.P. Creydt, C. Silberstein, E. Zotta, and C. Ibarra Cytotoxic effect of Shiga toxin-2 holotoxin and its B subunit on human renal tubular epithelial cells Microbes Infect. 8 2006 410 419
-
(2006)
Microbes Infect.
, vol.8
, pp. 410-419
-
-
Creydt, V.P.1
Silberstein, C.2
Zotta, E.3
Ibarra, C.4
-
8
-
-
3042544923
-
Structure of Shiga toxin type 2 (Stx2) from Escherichia coli O157:H7
-
M.E. Fraser, M. Fujinaga, M.M. Cherney, A.R. Melton-Celsa, E.M. Twiddy, A.D. O'Brien, and M.N. James Structure of shiga toxin type 2 (Stx2) from Escherichia coli O157:H7 J. Biol. Chem. 279 2004 27511 27517
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 27511-27517
-
-
Fraser, M.E.1
Fujinaga, M.2
Cherney, M.M.3
Melton-Celsa, A.R.4
Twiddy, E.M.5
O'Brien, A.D.6
James, M.N.7
-
9
-
-
0022508584
-
Pathogenesis of shigella diarrhea. XI. Isolation of a shigella toxin-binding glycolipid from rabbit jejunum and HeLa cells and its identification as globotriaosylceramide
-
M. Jacewicz, H. Clausen, E. Nudelman, A. Donohue-Rolfe, and G.T. Keusch Pathogenesis of shigella diarrhea. XI. Isolation of a shigella toxin-binding glycolipid from rabbit jejunum and HeLa cells and its identification as globotriaosylceramide J. Exp. Med. 163 1986 1391 1404
-
(1986)
J. Exp. Med.
, vol.163
, pp. 1391-1404
-
-
Jacewicz, M.1
Clausen, H.2
Nudelman, E.3
Donohue-Rolfe, A.4
Keusch, G.T.5
-
10
-
-
0021946215
-
The association between idiopathic hemolytic uremic syndrome and infection by verotoxin-producing Escherichia coli
-
M.A. Karmali, M. Petric, C. Lim, P.C. Fleming, G.S. Arbus, and H. Lior The association between idiopathic hemolytic uremic syndrome and infection by verotoxin-producing Escherichia coli J. Infect. Dis. 151 1985 775 782
-
(1985)
J. Infect. Dis.
, vol.151
, pp. 775-782
-
-
Karmali, M.A.1
Petric, M.2
Lim, C.3
Fleming, P.C.4
Arbus, G.S.5
Lior, H.6
-
11
-
-
0036890775
-
Haemolytic uraemic syndrome and thrombotic thrombocytopenic purpura
-
D. Karpman Haemolytic uraemic syndrome and thrombotic thrombocytopenic purpura Curr. Paediatr. 12 2002 569 574
-
(2002)
Curr. Paediatr.
, vol.12
, pp. 569-574
-
-
Karpman, D.1
-
12
-
-
2642704194
-
Apoptosis of renal cortical cells in the hemolytic-uremic syndrome: In vivo and in vitro studies
-
D. Karpman, A. Hakansson, M.T. Perez, C. Isaksson, E. Carlemalm, A. Caprioli, and C. Svanborg Apoptosis of renal cortical cells in the hemolytic-uremic syndrome: in vivo and in vitro studies Infect. Immun. 66 1998 636 644
-
(1998)
Infect. Immun.
, vol.66
, pp. 636-644
-
-
Karpman, D.1
Hakansson, A.2
Perez, M.T.3
Isaksson, C.4
Carlemalm, E.5
Caprioli, A.6
Svanborg, C.7
-
13
-
-
0037135608
-
Combinatorial ganglioside biosynthesis
-
T. Kolter, R.L. Proia, and K. Sandhoff Combinatorial ganglioside biosynthesis J. Biol. Chem. 277 2002 25859 25862
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25859-25862
-
-
Kolter, T.1
Proia, R.L.2
Sandhoff, K.3
-
14
-
-
84861380070
-
A comparison of Shiga-toxin 2 bacteriophage from classical enterohemorrhagic Escherichia coli serotypes and the German E. Coli O104:H4 outbreak strain
-
C.R. Laing, Y. Zhang, M.W. Gilmour, V. Allen, R. Johnson, J.E. Thomas, and V.P. Gannon A comparison of shiga-toxin 2 bacteriophage from classical enterohemorrhagic Escherichia coli serotypes and the German E. coli O104:H4 outbreak strain Plos One 7 2012 e37362
-
(2012)
Plos One
, vol.7
, pp. e37362
-
-
Laing, C.R.1
Zhang, Y.2
Gilmour, M.W.3
Allen, V.4
Johnson, R.5
Thomas, J.E.6
Gannon, V.P.7
-
15
-
-
0033591332
-
Improved inhibitors of glucosylceramide synthase
-
L. Lee, A. Abe, and J.A. Shayman Improved inhibitors of glucosylceramide synthase J. Biol. Chem. 274 1999 14662 14669
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 14662-14669
-
-
Lee, L.1
Abe, A.2
Shayman, J.A.3
-
16
-
-
0029916780
-
Role of verotoxin receptors in pathogenesis
-
C.A. Lingwood Role of verotoxin receptors in pathogenesis Trends Microbiol. 4 1996 147 153
-
(1996)
Trends Microbiol.
, vol.4
, pp. 147-153
-
-
Lingwood, C.A.1
-
17
-
-
34249306894
-
A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy of Gaucher disease
-
K.A. McEachern, J. Fung, S. Komarnitsky, C.S. Siegel, W.L. Chuang, E. Hutto, J.A. Shayman, G.A. Grabowski, J.M. Aerts, S.H. Cheng, D.P. Copeland, and J. Marshall A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy of Gaucher disease Mol. Genet. Metab. 91 2007 259 267
-
(2007)
Mol. Genet. Metab.
, vol.91
, pp. 259-267
-
-
McEachern, K.A.1
Fung, J.2
Komarnitsky, S.3
Siegel, C.S.4
Chuang, W.L.5
Hutto, E.6
Shayman, J.A.7
Grabowski, G.A.8
Aerts, J.M.9
Cheng, S.H.10
Copeland, D.P.11
Marshall, J.12
-
18
-
-
4844228035
-
A method for the isolation of glomerular and tubulointerstitial endothelial cells and a comparison of characteristics with the human umbilical vein endothelial cell model
-
S. McGinn, P. Poronnik, E.D. Gallery, and C.A. Pollock A method for the isolation of glomerular and tubulointerstitial endothelial cells and a comparison of characteristics with the human umbilical vein endothelial cell model Nephrology (Carlton) 9 2004 229 237
-
(2004)
Nephrology (Carlton)
, vol.9
, pp. 229-237
-
-
McGinn, S.1
Poronnik, P.2
Gallery, E.D.3
Pollock, C.A.4
-
19
-
-
24644519117
-
Epigallocatechin-3-gallate suppresses galactose-alpha1,4-galactose-1beta,4-glucose ceramide expression in TNF-alpha stimulated human intestinal epithelial cells through inhibition of MAPKs and NF-kappaB
-
D.O. Moon, S.R. Choi, C.M. Lee, G.Y. Kim, H.J. Lee, and Y.M. Park Epigallocatechin-3-gallate suppresses galactose-alpha1,4-galactose-1beta,4-glucose ceramide expression in TNF-alpha stimulated human intestinal epithelial cells through inhibition of MAPKs and NF-kappaB J. Korean Med. Sci. 20 2005 548 554
-
(2005)
J. Korean Med. Sci.
, vol.20
, pp. 548-554
-
-
Moon, D.O.1
Choi, S.R.2
Lee, C.M.3
Kim, G.Y.4
Lee, H.J.5
Park, Y.M.6
-
20
-
-
33745685704
-
Curcumin decreases binding of Shiga-like toxin-1B on human intestinal epithelial cell line HT29 stimulated with TNF-alpha and IL-1beta: Suppression of p38, JNK and NF-kappaB p65 as potential targets
-
D.O. Moon, C.Y. Jin, J.D. Lee, Y.H. Choi, S.C. Ahn, C.M. Lee, S.C. Jeong, Y.M. Park, and G.Y. Kim Curcumin decreases binding of Shiga-like toxin-1B on human intestinal epithelial cell line HT29 stimulated with TNF-alpha and IL-1beta: suppression of p38, JNK and NF-kappaB p65 as potential targets Biol. Pharm. Bull. 29 2006 1470 1475
-
(2006)
Biol. Pharm. Bull.
, vol.29
, pp. 1470-1475
-
-
Moon, D.O.1
Jin, C.Y.2
Lee, J.D.3
Choi, Y.H.4
Ahn, S.C.5
Lee, C.M.6
Jeong, S.C.7
Park, Y.M.8
Kim, G.Y.9
-
21
-
-
79952087639
-
Escherichia coli Shiga toxin mechanisms of action in renal disease
-
T.G. Obrig Escherichia coli shiga toxin mechanisms of action in renal disease Toxins (Basel) 2 2010 2769 2794
-
(2010)
Toxins (Basel)
, vol.2
, pp. 2769-2794
-
-
Obrig, T.G.1
-
22
-
-
0027185787
-
Endothelial heterogeneity in Shiga toxin receptors and responses
-
T.G. Obrig, C.B. Louise, C.A. Lingwood, B. Boyd, L. Barley-Maloney, and T.O. Daniel Endothelial heterogeneity in Shiga toxin receptors and responses J. Biol. Chem. 268 1993 15484 15488
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 15484-15488
-
-
Obrig, T.G.1
Louise, C.B.2
Lingwood, C.A.3
Boyd, B.4
Barley-Maloney, L.5
Daniel, T.O.6
-
23
-
-
0026605452
-
Binding of verocytotoxin 1 to its receptor is influenced by differences in receptor fatty acid content
-
A. Pellizzari, H. Pang, and C.A. Lingwood Binding of verocytotoxin 1 to its receptor is influenced by differences in receptor fatty acid content Biochemistry 31 1992 1363 1370
-
(1992)
Biochemistry
, vol.31
, pp. 1363-1370
-
-
Pellizzari, A.1
Pang, H.2
Lingwood, C.A.3
-
24
-
-
84899654991
-
Genotypic characterization of Escherichia coli O157:H7 strains that cause diarrhea and hemolytic uremic syndrome in Neuquen, Argentina
-
L. Pianciola, I. Chinen, M. Mazzeo, E. Miliwebsky, G. Gonzalez, C. Muller, C. Carbonari, M. Navello, E. Zitta, and M. Rivas Genotypic characterization of Escherichia coli O157:H7 strains that cause diarrhea and hemolytic uremic syndrome in Neuquen, Argentina Int. J. Med. Microbiol. 304 2014 499 504
-
(2014)
Int. J. Med. Microbiol.
, vol.304
, pp. 499-504
-
-
Pianciola, L.1
Chinen, I.2
Mazzeo, M.3
Miliwebsky, E.4
Gonzalez, G.5
Muller, C.6
Carbonari, C.7
Navello, M.8
Zitta, E.9
Rivas, M.10
-
25
-
-
0028176432
-
N-butyldeoxynojirimycin is a novel inhibitor of glycolipid biosynthesis
-
F.M. Platt, G.R. Neises, R.A. Dwek, and T.D. Butters N-butyldeoxynojirimycin is a novel inhibitor of glycolipid biosynthesis J. Biol. Chem. 269 1994 8362 8365
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 8362-8365
-
-
Platt, F.M.1
Neises, G.R.2
Dwek, R.A.3
Butters, T.D.4
-
26
-
-
0030814767
-
Extensive glycosphingolipid depletion in the liver and lymphoid organs of mice treated with N-butyldeoxynojirimycin
-
F.M. Platt, G. Reinkensmeier, R.A. Dwek, and T.D. Butters Extensive glycosphingolipid depletion in the liver and lymphoid organs of mice treated with N-butyldeoxynojirimycin J. Biol. Chem. 272 1997 19365 19372
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 19365-19372
-
-
Platt, F.M.1
Reinkensmeier, G.2
Dwek, R.A.3
Butters, T.D.4
-
27
-
-
84905922631
-
Direct acute tubular damage contributes to Shigatoxin-mediated kidney failure
-
S. Porubsky, G. Federico, J. Muthing, R. Jennemann, N. Gretz, S. Buttner, N. Obermuller, O. Jung, I.A. Hauser, E. Grone, H. Geiger, H.J. Grone, and C. Betz Direct acute tubular damage contributes to Shigatoxin-mediated kidney failure J. Pathol. 234 2014 120 133
-
(2014)
J. Pathol.
, vol.234
, pp. 120-133
-
-
Porubsky, S.1
Federico, G.2
Muthing, J.3
Jennemann, R.4
Gretz, N.5
Buttner, S.6
Obermuller, N.7
Jung, O.8
Hauser, I.A.9
Grone, E.10
Geiger, H.11
Grone, H.J.12
Betz, C.13
-
28
-
-
0031463774
-
Epidemic hemolytic-uremic syndrome in children
-
H.A. Repetto Epidemic hemolytic-uremic syndrome in children Kidney Int. 52 1997 1708 1719
-
(1997)
Kidney Int.
, vol.52
, pp. 1708-1719
-
-
Repetto, H.A.1
-
29
-
-
33845775695
-
The epidemiology of hemolytic uremic syndrome in Argentina. Diagnosis of the etiologic agent, reservoirs and routes of transmission
-
M. Rivas, E. Miliwebsky, I. Chinen, N. Deza, and G.A. Leotta The epidemiology of hemolytic uremic syndrome in Argentina. Diagnosis of the etiologic agent, reservoirs and routes of transmission Medicina (B Aires) 66 Suppl. l3 2006 27 32
-
(2006)
Medicina (B Aires)
, vol.66
, pp. 27-32
-
-
Rivas, M.1
Miliwebsky, E.2
Chinen, I.3
Deza, N.4
Leotta, G.A.5
-
30
-
-
33645705787
-
Characterization and epidemiologic subtyping of Shiga toxin-producing Escherichia coli strains isolated from hemolytic uremic syndrome and diarrhea cases in Argentina
-
M. Rivas, E. Miliwebsky, I. Chinen, C.D. Roldan, L. Balbi, B. Garcia, G. Fiorilli, S. Sosa-Estani, J. Kincaid, J. Rangel, and P.M. Griffin Characterization and epidemiologic subtyping of Shiga toxin-producing Escherichia coli strains isolated from hemolytic uremic syndrome and diarrhea cases in Argentina Foodborne Pathog. Dis. 3 2006 88 96
-
(2006)
Foodborne Pathog. Dis.
, vol.3
, pp. 88-96
-
-
Rivas, M.1
Miliwebsky, E.2
Chinen, I.3
Roldan, C.D.4
Balbi, L.5
Garcia, B.6
Fiorilli, G.7
Sosa-Estani, S.8
Kincaid, J.9
Rangel, J.10
Griffin, P.M.11
-
31
-
-
0028352977
-
Retrograde transport from the Golgi complex to the ER of both Shiga toxin and the nontoxic Shiga B-fragment is regulated by butyric acid and cAMP
-
K. Sandvig, M. Ryd, O. Garred, E. Schweda, P.K. Holm, and B. van Deurs Retrograde transport from the Golgi complex to the ER of both Shiga toxin and the nontoxic Shiga B-fragment is regulated by butyric acid and cAMP J. Cell. Biol. 126 1994 53 64
-
(1994)
J. Cell. Biol.
, vol.126
, pp. 53-64
-
-
Sandvig, K.1
Ryd, M.2
Garred, O.3
Schweda, E.4
Holm, P.K.5
Van Deurs, B.6
-
32
-
-
70350663882
-
A glucosylceramide synthase inhibitor prevents the cytotoxic effects of Shiga toxin-2 on human renal tubular epithelial cells
-
C.D. Silbertsein C, W.L. Chiang, H.A. Repetto, and C. Ibarra A glucosylceramide synthase inhibitor prevents the cytotoxic effects of shiga toxin-2 on human renal tubular epithelial cells J. Epithel. Biol. Pharmacol. 1 2008 71 75
-
(2008)
J. Epithel. Biol. Pharmacol.
, vol.1
, pp. 71-75
-
-
Silbertsein, C.C.D.1
Chiang, W.L.2
Repetto, H.A.3
Ibarra, C.4
-
33
-
-
15244348050
-
Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome
-
P.I. Tarr, C.A. Gordon, and W.L. Chandler Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome Lancet 365 2005 1073 1086
-
(2005)
Lancet
, vol.365
, pp. 1073-1086
-
-
Tarr, P.I.1
Gordon, C.A.2
Chandler, W.L.3
-
34
-
-
83655201339
-
Activation of cell stress response pathways by Shiga toxins
-
V.L. Tesh Activation of cell stress response pathways by Shiga toxins Cell Microbiol. 14 2012 1 9
-
(2012)
Cell Microbiol.
, vol.14
, pp. 1-9
-
-
Tesh, V.L.1
-
35
-
-
33947314170
-
The pharmacokinetics and tissue distribution of the glucosylceramide synthase inhibitor miglustat in the rat
-
A. Treiber, O. Morand, and M. Clozel The pharmacokinetics and tissue distribution of the glucosylceramide synthase inhibitor miglustat in the rat Xenobiotica 37 2007 298 314
-
(2007)
Xenobiotica
, vol.37
, pp. 298-314
-
-
Treiber, A.1
Morand, O.2
Clozel, M.3
-
36
-
-
34248228704
-
Inhibiting glycosphingolipid synthesis improves glycemic control and insulin sensitivity in animal models of type 2 diabetes
-
H. Zhao, M. Przybylska, I.H. Wu, J. Zhang, C. Siegel, S. Komarnitsky, N.S. Yew, and S.H. Cheng Inhibiting glycosphingolipid synthesis improves glycemic control and insulin sensitivity in animal models of type 2 diabetes Diabetes 56 2007 1210 1218
-
(2007)
Diabetes
, vol.56
, pp. 1210-1218
-
-
Zhao, H.1
Przybylska, M.2
Wu, I.H.3
Zhang, J.4
Siegel, C.5
Komarnitsky, S.6
Yew, N.S.7
Cheng, S.H.8
|