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Volumn 51, Issue 4, 2016, Pages 357-369

N-Acetylglucosaminyltransferase V exacerbates murine colitis with macrophage dysfunction and enhances colitic tumorigenesis

Author keywords

Colitic cancer; Macrophage; N Acetylglucosaminyltransferase V; Phagocytosis; Tumorigenesis

Indexed keywords

CLODRONIC ACID; DEXTRAN SULFATE; INTERLEUKIN 10; LATEX; LECTIN; LIPOSOME; N ACETYLGLUCOSAMINYLTRANSFERASE; PHYTOHEMAGGLUTININ; TRINITROBENZENESULFONIC ACID; ALPHA-1,6-MANNOSYLGLYCOPROTEIN BETA 1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE; CYTOKINE;

EID: 84940987128     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-015-1119-3     Document Type: Article
Times cited : (10)

References (41)
  • 1
    • 79251489778 scopus 로고    scopus 로고
    • Glycomics hits the big time
    • COI: 1:CAS:528:DC%2BC3cXhsVygsLbN, PID: 21111227
    • Hart GW, Copeland RJ. Glycomics hits the big time. Cell. 2010;143:672–6.
    • (2010) Cell , vol.143 , pp. 672-676
    • Hart, G.W.1    Copeland, R.J.2
  • 2
    • 0032429137 scopus 로고    scopus 로고
    • The effect on IgG glycosylation of altering β1,4-galactosyltransferase-1 activity in B cells
    • COI: 1:CAS:528:DyaK1MXivVWn, PID: 9858643
    • Keusch J, Lydyard PM, Delves PJ. The effect on IgG glycosylation of altering β1,4-galactosyltransferase-1 activity in B cells. Glycobiology. 1998;8:1215–20.
    • (1998) Glycobiology , vol.8 , pp. 1215-1220
    • Keusch, J.1    Lydyard, P.M.2    Delves, P.J.3
  • 3
    • 42449143890 scopus 로고    scopus 로고
    • Branched N-glycans regulate the biological functions of integrins and cadherins
    • COI: 1:CAS:528:DC%2BD1cXlslCrtL4%3D, PID: 18384383
    • Zhao Y, Sato Y, Isaji T, et al. Branched N-glycans regulate the biological functions of integrins and cadherins. FEBS J. 2008;275:1939–48.
    • (2008) FEBS J , vol.275 , pp. 1939-1948
    • Zhao, Y.1    Sato, Y.2    Isaji, T.3
  • 4
    • 0032869011 scopus 로고    scopus 로고
    • Implication of N-acetylglucosaminyltransferases III and V in cancer: gene regulation and signaling mechanism
    • COI: 1:CAS:528:DyaK1MXntlOhu7Y%3D, PID: 10571019
    • Taniguchi N, Miyoshi E, Ko JH, et al. Implication of N-acetylglucosaminyltransferases III and V in cancer: gene regulation and signaling mechanism. Biochim Biophys Acta. 1999;1455:287–300.
    • (1999) Biochim Biophys Acta , vol.1455 , pp. 287-300
    • Taniguchi, N.1    Miyoshi, E.2    Ko, J.H.3
  • 5
    • 0035526266 scopus 로고    scopus 로고
    • Implication of GnT-V in cancer metastasis: a glycomic approach for identification of a target protein and its unique function as an angiogenic cofactor
    • COI: 1:CAS:528:DC%2BD3sXotVyktQ%3D%3D, PID: 12820719
    • Taniguchi N, Ihara S, Saito T, et al. Implication of GnT-V in cancer metastasis: a glycomic approach for identification of a target protein and its unique function as an angiogenic cofactor. Glycoconj J. 2001;18:859–65.
    • (2001) Glycoconj J , vol.18 , pp. 859-865
    • Taniguchi, N.1    Ihara, S.2    Saito, T.3
  • 6
    • 0034061923 scopus 로고    scopus 로고
    • Suppression of tumor growth and metastasis in Mgat5-deficient mice
    • COI: 1:CAS:528:DC%2BD3cXhslygs78%3D, PID: 10700233
    • Granovsky M, Fata J, Pawling J, et al. Suppression of tumor growth and metastasis in Mgat5-deficient mice. Nat Med. 2000;6:306–12.
    • (2000) Nat Med , vol.6 , pp. 306-312
    • Granovsky, M.1    Fata, J.2    Pawling, J.3
  • 7
    • 49149107798 scopus 로고    scopus 로고
    • Knockdown of Mgat5 inhibits breast cancer cell growth with activation of CD4+ T cells and macrophages
    • COI: 1:CAS:528:DC%2BD1cXit1Oks7c%3D, PID: 18292539
    • Li D, Li Y, Wu X, et al. Knockdown of Mgat5 inhibits breast cancer cell growth with activation of CD4+ T cells and macrophages. J Immunol. 2008;180:3158–65.
    • (2008) J Immunol. , vol.180 , pp. 3158-3165
    • Li, D.1    Li, Y.2    Wu, X.3
  • 8
    • 0027213481 scopus 로고
    • N-Acetylglucosaminyltransferase III and V messenger RNA levels in LEC rats during hepatocarcinogenesis
    • COI: 1:CAS:528:DyaK2cXlvVOj, PID: 8240532
    • Miyoshi E, Nishikawa A, Ihara Y, et al. N-Acetylglucosaminyltransferase III and V messenger RNA levels in LEC rats during hepatocarcinogenesis. Cancer Res. 1993;53:3899–902.
    • (1993) Cancer Res , vol.53 , pp. 3899-3902
    • Miyoshi, E.1    Nishikawa, A.2    Ihara, Y.3
  • 9
    • 0028847193 scopus 로고
    • Gene expression of N-acetylglucosaminyltransferases III and V: a possible implication for liver regeneration
    • COI: 1:CAS:528:DyaK28XmvV2rsw%3D%3D, PID: 7489997
    • Miyoshi E, Ihara Y, Nishikawa A, et al. Gene expression of N-acetylglucosaminyltransferases III and V: a possible implication for liver regeneration. Hepatology. 1995;22:1847–55.
    • (1995) Hepatology , vol.22 , pp. 1847-1855
    • Miyoshi, E.1    Ihara, Y.2    Nishikawa, A.3
  • 10
    • 84863086426 scopus 로고    scopus 로고
    • Upregulation of N-acetylglucosaminyltransferase-V by heparin-binding EGF-like growth factor induces keratinocyte proliferation and epidermal hyperplasia
    • COI: 1:CAS:528:DC%2BC38XhtlantL3L, PID: 22716246
    • Kimura A, Terao M, Kato A, et al. Upregulation of N-acetylglucosaminyltransferase-V by heparin-binding EGF-like growth factor induces keratinocyte proliferation and epidermal hyperplasia. Exp Dermatol. 2012;21:515–9.
    • (2012) Exp Dermatol , vol.21 , pp. 515-519
    • Kimura, A.1    Terao, M.2    Kato, A.3
  • 11
    • 80051500237 scopus 로고    scopus 로고
    • Enhanced epithelial-mesenchymal transition-like phenotype in N-acetylglucosaminyltransferase V transgenic mouse skin promotes wound healing
    • COI: 1:CAS:528:DC%2BC3MXpsl2msLo%3D, PID: 21697088
    • Terao M, Ishikawa A, Nakahara S, et al. Enhanced epithelial-mesenchymal transition-like phenotype in N-acetylglucosaminyltransferase V transgenic mouse skin promotes wound healing. J Biol Chem. 2011;286:28303–11.
    • (2011) J Biol Chem , vol.286 , pp. 28303-28311
    • Terao, M.1    Ishikawa, A.2    Nakahara, S.3
  • 12
    • 84884650652 scopus 로고    scopus 로고
    • Diet, microbes, and host genetics: the perfect storm in inflammatory bowel diseases
    • COI: 1:CAS:528:DC%2BC3sXlslShsbo%3D, PID: 23475322
    • Leone V, Chang EB, Devkota S. Diet, microbes, and host genetics: the perfect storm in inflammatory bowel diseases. J Gastroenterol. 2013;48:315–21.
    • (2013) J Gastroenterol , vol.48 , pp. 315-321
    • Leone, V.1    Chang, E.B.2    Devkota, S.3
  • 13
    • 3042599473 scopus 로고    scopus 로고
    • Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation
    • COI: 1:CAS:528:DC%2BD2cXlvFOhu7s%3D, PID: 15194558
    • Itzkowitz SH, Yio X. Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. Am J Physiol Gastrointest Liver Physiol. 2004;287:G7–17.
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.287 , pp. G7-G17
    • Itzkowitz, S.H.1    Yio, X.2
  • 14
    • 43549098797 scopus 로고    scopus 로고
    • IgG oligosaccharide alterations are a novel diagnostic marker for disease activity and the clinical course of inflammatory bowel disease
    • PID: 18177457
    • Shinzaki S, Iijima H, Nakagawa T, et al. IgG oligosaccharide alterations are a novel diagnostic marker for disease activity and the clinical course of inflammatory bowel disease. Am J Gastroenterol. 2008;103:1173–81.
    • (2008) Am J Gastroenterol , vol.103 , pp. 1173-1181
    • Shinzaki, S.1    Iijima, H.2    Nakagawa, T.3
  • 15
    • 84860224921 scopus 로고    scopus 로고
    • Altered oligosaccharide structures reduce colitis induction in mice defective in β-1,4-galactosyltransferase
    • COI: 1:CAS:528:DC%2BC38XktlCis7g%3D, PID: 22333949
    • Shinzaki S, Iijima H, Fujii H, et al. Altered oligosaccharide structures reduce colitis induction in mice defective in β-1,4-galactosyltransferase. Gastroenterology. 2012;142:1172–82.
    • (2012) Gastroenterology , vol.142 , pp. 1172-1182
    • Shinzaki, S.1    Iijima, H.2    Fujii, H.3
  • 17
    • 10744222880 scopus 로고    scopus 로고
    • Specific regulation of T helper cell 1-mediated murine colitis by CEACAM1
    • COI: 1:CAS:528:DC%2BD2cXhsFKhurk%3D, PID: 14970176
    • Iijima H, Neurath MF, Nagaishi T, et al. Specific regulation of T helper cell 1-mediated murine colitis by CEACAM1. J Exp Med. 2004;199:471–82.
    • (2004) J Exp Med , vol.199 , pp. 471-482
    • Iijima, H.1    Neurath, M.F.2    Nagaishi, T.3
  • 18
    • 14944365560 scopus 로고    scopus 로고
    • Therapeutic potential of follistatin for colonic inflammation in mice
    • COI: 1:CAS:528:DC%2BD2MXitVemsb0%3D, PID: 15685552
    • Dohi T, Ejima C, Kato R, et al. Therapeutic potential of follistatin for colonic inflammation in mice. Gastroenterology. 2005;128:411–23.
    • (2005) Gastroenterology , vol.128 , pp. 411-423
    • Dohi, T.1    Ejima, C.2    Kato, R.3
  • 19
    • 0031775496 scopus 로고    scopus 로고
    • Involvement of insulin-like growth factor-1 and its binding proteins in proliferation and differentiation of murine bone marrow-derived macrophage precursors
    • COI: 1:CAS:528:DyaK1cXnsVSjtLY%3D, PID: 9867252
    • Long E, Huynh HT, Zhao X. Involvement of insulin-like growth factor-1 and its binding proteins in proliferation and differentiation of murine bone marrow-derived macrophage precursors. Endocrine. 1998;9:185–92.
    • (1998) Endocrine , vol.9 , pp. 185-192
    • Long, E.1    Huynh, H.T.2    Zhao, X.3
  • 20
    • 0026644615 scopus 로고
    • Effects of the lpr/lpr mutation on T and B cell populations in the lamina propria of the small intestine, a mucosal effector site
    • COI: 1:STN:280:DyaK3s%2Fgt1Omug%3D%3D, PID: 1390438
    • Aicher WK, Fujihashi K, Yamamoto M, et al. Effects of the lpr/lpr mutation on T and B cell populations in the lamina propria of the small intestine, a mucosal effector site. Int Immunol. 1992;4:959–68.
    • (1992) Int Immunol , vol.4 , pp. 959-968
    • Aicher, W.K.1    Fujihashi, K.2    Yamamoto, M.3
  • 21
    • 0025354406 scopus 로고
    • Laboratory models of sepsis and septic shock
    • COI: 1:STN:280:DyaK3czjvFymsA%3D%3D, PID: 2199735
    • Fink MP, Heard SO. Laboratory models of sepsis and septic shock. J Surg Res. 1990;49:186–96.
    • (1990) J Surg Res , vol.49 , pp. 186-196
    • Fink, M.P.1    Heard, S.O.2
  • 22
    • 80052356325 scopus 로고    scopus 로고
    • SHIP-deficient, alternatively activated macrophages protect mice during DSS-induced colitis
    • COI: 1:CAS:528:DC%2BC3MXht1SisLvP, PID: 21685246
    • Weisser SB, Brugger HK, Voglmaier NS, et al. SHIP-deficient, alternatively activated macrophages protect mice during DSS-induced colitis. J Leukoc Biol. 2011;90:483–92.
    • (2011) J Leukoc Biol , vol.90 , pp. 483-492
    • Weisser, S.B.1    Brugger, H.K.2    Voglmaier, N.S.3
  • 23
    • 0028006855 scopus 로고
    • Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice
    • COI: 1:CAS:528:DyaK2MXivFSls7s%3D, PID: 7958674
    • Dieleman LA, Ridwan BU, Tennyson GS, et al. Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice. Gastroenterology. 1994;107:1643–52.
    • (1994) Gastroenterology , vol.107 , pp. 1643-1652
    • Dieleman, L.A.1    Ridwan, B.U.2    Tennyson, G.S.3
  • 24
    • 34347262689 scopus 로고    scopus 로고
    • Chemically induced mouse models of intestinal inflammation
    • COI: 1:CAS:528:DC%2BD2sXhtFGntbnL, PID: 17406617
    • Wirtz S, Neufert C, Weigmann B, et al. Chemically induced mouse models of intestinal inflammation. Nat Protoc. 2007;2:541–6.
    • (2007) Nat Protoc , vol.2 , pp. 541-546
    • Wirtz, S.1    Neufert, C.2    Weigmann, B.3
  • 25
    • 34547993629 scopus 로고    scopus 로고
    • Therapeutic effect of nimesulide on colorectal carcinogenesis in experimental murine ulcerative colitis
    • COI: 1:CAS:528:DC%2BD2sXhtFGgtLfI, PID: 17716351
    • Inoue T, Murano M, Abe Y, et al. Therapeutic effect of nimesulide on colorectal carcinogenesis in experimental murine ulcerative colitis. J Gastroenterol Hepatol. 2007;22:1474–81.
    • (2007) J Gastroenterol Hepatol , vol.22 , pp. 1474-1481
    • Inoue, T.1    Murano, M.2    Abe, Y.3
  • 26
    • 0027521572 scopus 로고
    • Interleukin-10-deficient mice develop chronic enterocolitis
    • COI: 1:STN:280:DyaK2c%2Fgs1Gmug%3D%3D, PID: 8402911
    • Kuhn R, Lohler J, Rennick D, et al. Interleukin-10-deficient mice develop chronic enterocolitis. Cell. 1993;75:263–74.
    • (1993) Cell , vol.75 , pp. 263-274
    • Kuhn, R.1    Lohler, J.2    Rennick, D.3
  • 27
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • COI: 1:CAS:528:DC%2BD3sXovVw%3D, PID: 12511873
    • Gordon S. Alternative activation of macrophages. Nat Rev Immunol. 2003;3:23–35.
    • (2003) Nat Rev Immunol , vol.3 , pp. 23-35
    • Gordon, S.1
  • 28
    • 33845398215 scopus 로고    scopus 로고
    • Biochemical and functional characterization of three activated macrophage populations
    • COI: 1:CAS:528:DC%2BD28XhtlSisLnI, PID: 16905575
    • Edwards JP, Zhang X, Frauwirth KA, et al. Biochemical and functional characterization of three activated macrophage populations. J Leukoc Biol. 2006;80:1298–307.
    • (2006) J Leukoc Biol , vol.80 , pp. 1298-1307
    • Edwards, J.P.1    Zhang, X.2    Frauwirth, K.A.3
  • 29
    • 33751563152 scopus 로고    scopus 로고
    • Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals
    • COI: 1:CAS:528:DC%2BD28Xht1WrsL7P, PID: 17114424
    • Boonstra A, Rajsbaum R, Holman M, et al. Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals. J Immunol. 2006;177:7551–8.
    • (2006) J Immunol , vol.177 , pp. 7551-7558
    • Boonstra, A.1    Rajsbaum, R.2    Holman, M.3
  • 30
    • 70350464351 scopus 로고    scopus 로고
    • Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis
    • COI: 1:CAS:528:DC%2BD1MXhtFygsLbJ, PID: 19783988
    • Murai M, Turovskaya O, Kim G, et al. Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis. Nat Immunol. 2009;10:1178–84.
    • (2009) Nat Immunol , vol.10 , pp. 1178-1184
    • Murai, M.1    Turovskaya, O.2    Kim, G.3
  • 31
    • 35649024275 scopus 로고    scopus 로고
    • Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins
    • COI: 1:CAS:528:DC%2BD2sXhtFGns73M, PID: 17895374
    • Lacy-Hulbert A, Smith AM, Tissire H, et al. Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins. Proc Natl Acad Sci U S A. 2007;104:15823–8.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 15823-15828
    • Lacy-Hulbert, A.1    Smith, A.M.2    Tissire, H.3
  • 32
    • 37049031230 scopus 로고    scopus 로고
    • Interleukin-10 expression in macrophages during phagocytosis of apoptotic cells is mediated by homeodomain proteins Pbx1 and Prep-1
    • COI: 1:CAS:528:DC%2BD1cXotFal, PID: 18093541
    • Chung EY, Liu J, Homma Y, et al. Interleukin-10 expression in macrophages during phagocytosis of apoptotic cells is mediated by homeodomain proteins Pbx1 and Prep-1. Immunity. 2007;27:952–64.
    • (2007) Immunity , vol.27 , pp. 952-964
    • Chung, E.Y.1    Liu, J.2    Homma, Y.3
  • 33
    • 27744437941 scopus 로고    scopus 로고
    • Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria
    • COI: 1:CAS:528:DC%2BD2MXhtF2ju7nM, PID: 16272349
    • Kamada N, Hisamatsu T, Okamoto S, et al. Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria. J Immunol. 2005;175:6900–8.
    • (2005) J Immunol , vol.175 , pp. 6900-6908
    • Kamada, N.1    Hisamatsu, T.2    Okamoto, S.3
  • 34
    • 0037317763 scopus 로고    scopus 로고
    • Innate immune sensing and its roots: the story of endotoxin
    • COI: 1:CAS:528:DC%2BD3sXot12nsw%3D%3D, PID: 12563300
    • Beutler B, Rietschel ET. Innate immune sensing and its roots: the story of endotoxin. Nat Rev Immunol. 2003;3:169–76.
    • (2003) Nat Rev Immunol , vol.3 , pp. 169-176
    • Beutler, B.1    Rietschel, E.T.2
  • 35
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • COI: 1:CAS:528:DC%2BD28Xit1Kltb8%3D, PID: 16497588
    • Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell. 2006;124:783–801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 36
    • 3242664636 scopus 로고    scopus 로고
    • Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
    • COI: 1:CAS:528:DC%2BD2cXmtlKntrg%3D, PID: 15260992
    • Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, et al. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell. 2004;118:229–41.
    • (2004) Cell , vol.118 , pp. 229-241
    • Rakoff-Nahoum, S.1    Paglino, J.2    Eslami-Varzaneh, F.3
  • 37
    • 0032509295 scopus 로고    scopus 로고
    • Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene
    • COI: 1:CAS:528:DyaK1cXotVyjsbk%3D, PID: 9851930
    • Poltorak A, He X, Smirnova I, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science. 1998;282:2085–8.
    • (1998) Science , vol.282 , pp. 2085-2088
    • Poltorak, A.1    He, X.2    Smirnova, I.3
  • 38
    • 77955403878 scopus 로고    scopus 로고
    • A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release
    • COI: 1:CAS:528:DC%2BC3cXovVGku78%3D, PID: 20547845
    • Yang H, Hreggvidsdottir HS, Palmblad K, et al. A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release. Proc Natl Acad Sci U S A. 2010;107:11942–7.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 11942-11947
    • Yang, H.1    Hreggvidsdottir, H.S.2    Palmblad, K.3
  • 39
    • 77955829289 scopus 로고    scopus 로고
    • Fungal pathogen recognition by scavenger receptors in nematodes and mammals
    • PID: 21178411
    • Means TK. Fungal pathogen recognition by scavenger receptors in nematodes and mammals. Virulence. 2010;1:37–41.
    • (2010) Virulence , vol.1 , pp. 37-41
    • Means, T.K.1
  • 40
    • 70349506775 scopus 로고    scopus 로고
    • 88 of Toll-like receptor 4 highlights the critical role of MD-2 in cell surface receptor expression
    • COI: 1:CAS:528:DC%2BD1MXptlamtrw%3D, PID: 19556306
    • 88 of Toll-like receptor 4 highlights the critical role of MD-2 in cell surface receptor expression. Int Immunol. 2009;21:925–34.
    • (2009) Int Immunol , vol.21 , pp. 925-934
    • Nishitani, C.1    Takahashi, M.2    Mitsuzawa, H.3
  • 41
    • 34547889114 scopus 로고    scopus 로고
    • Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer’s disease patients are improved by bisdemethoxycurcumin
    • COI: 1:CAS:528:DC%2BD2sXptVejtLg%3D, PID: 17652175
    • Fiala M, Liu PT, Espinosa-Jeffrey A, et al. Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer’s disease patients are improved by bisdemethoxycurcumin. Proc Natl Acad Sci U S A. 2007;104:12849–54.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 12849-12854
    • Fiala, M.1    Liu, P.T.2    Espinosa-Jeffrey, A.3


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