Profiling Analysis of Low Molecular Weight Heparins by Multiple Heart-Cutting Two Dimensional Chromatography with Quadruple Time-of-Flight Mass Spectrometry

Analytical Chemistry

Volumn 87, Issue 17, 2015, Pages 8957-8963

  Ouyang, Yilan ^a   Zeng, Yangyang ^b   Rong, Yinxiu ^a   Song, Yue ^c   Shi, Lv ^b   Chen, Bo ^c   Yang, Xinlei ^c   Xu, Naiyu ^a   Linhardt, Robert J ^d   Zhang, Zhenqing ^a  

^a SOOCHOW UNIVERSITY   (China)

^b Department of Medicine   (China)

^c Agility Group (China) Ltd   (China)

^d RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATOGRAPHY; DRUG PRODUCTS; ION CHROMATOGRAPHY; IONIC LIQUIDS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR WEIGHT; OLIGOSACCHARIDES; POLYSACCHARIDES; QUALITY CONTROL; SPECTROMETRY;

LOW MOLECULAR WEIGHT HEPARIN (LMWHS); LOW-MOLECULAR WEIGHT HEPARINS; QUADRUPOLE TIME OF FLIGHT MASS SPECTROMETRY; REVERSED PHASE CHROMATOGRAPHY; TIME OF FLIGHT MASS SPECTROMETRY; TWO-DIMENSIONAL CHROMATOGRAPHY; TWO-DIMENSIONAL SEPARATIONS; ULTRA-HIGH PERFORMANCE LIQUID CHROMATOGRAPHIES;

SIZE EXCLUSION CHROMATOGRAPHY;

LOW MOLECULAR WEIGHT HEPARIN;

CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; TIME FACTOR;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HEPARIN, LOW-MOLECULAR-WEIGHT; MASS SPECTROMETRY; TIME FACTORS;

EID: 84940983720     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/acs.analchem.5b02218     Document Type: Article

References (32)

1. Linhardt, R. J. Chem. Indus. 1991, 2, 45-50
2. Liu, H.; Zhang, Z.; Linhardt, R. T. Nat. Prod. Rep. 2009, 26, 313-321 10.1039/b819896a
3. Lindahl, U.; Baeckstroem, G.; Thunberg, L.; Leder, I. G. Proc. Natl. Acad. Sci. U. S. A. 1980, 77, 6551-6555 10.1073/pnas.77.11.6551
4. Atha, D. H.; Lormeau, J. C.; Petitou, M.; Rosenberg, R. D.; Choay, J. Biochemistry 1985, 24, 6723-9729 10.1021/bi00344a063
5. Ahsan, A.; Jeske, W.; Hoppensteadt, D.; Lormeau, J. C.; Wolf, H.; Fareed, J. J. Pharm. Sci. 1995, 84, 724-727 10.1002/jps.2600840612
6. Linhardt, R. J.; Rice, K. G.; Kim, Y. S.; Lohse, D. L.; Wang, H. M.; Loganathan, D. Biochem. J. 1988, 254 (3) 781-787
7. Capila, I.; Linhardt, R. J. Angew. Chem., Int. Ed. 2002, 41, 390-412 10.1002/1521-3773(20020201)41:3<390::AID-ANIE390>3.0.CO;2-B
8. Kishimoto, T. K.; Viswanathan, K.; Ganguly, T.; Elankumaran, S.; Smith, S.; Pelzer, K.; Lansing, J. C.; Sriranganathan, N.; Zhao, G.; Galcheva-Gargova, Z.; Al-Hakim, A.; Bailey, G. S.; Fraser, B.; Roy, S.; Rogers-Cotrone, T.; Buhse, L.; Whary, M.; Fox, J.; Nasr, M.; Dal Pan, G. J.; Shriver, Z.; Langer, R. S.; Venkataraman, G.; Austen, K. F.; Woodcock, J.; Sasisekharan, R. N. Engl. J. Med. 2008, 358, 2457-2467 10.1056/NEJMoa0803200
9. Laurencin, C. T.; Nair, L. Nat. Biotechnol. 2008, 26, 621-623 10.1038/nbt0608-621
10. Guerrini, M.; Beccati, D.; Shriver, Z.; Naggi, A.; Viswanathan, K.; Bisio, A.; Capila, I.; Lansing, J. C.; Guglieri, S.; Fraser, B.; Al-Hakim, A.; Gunay, N. S.; Zhang, Z.; Robinson, L.; Buhse, L.; Nasr, M.; Woodcock, J.; Langer, R.; Venkataraman, G.; Linhardt, R. J.; Casu, B.; Torri, G.; Sasisekharan, R. Nat. Biotechnol. 2008, 26, 669-675 10.1038/nbt1407
11. Barrowcliffe, T. W. Br. J. Haematol. 1995, 90, 1-7 10.1111/j.1365-2141.1995.tb03373.x
12. Linhardt, R. J.; Gunay, N. S. Semin. Thromb. Hemost. 1999, 25 (Suppl 3) 5-16
13. Castro-Lopez, V.; Harris, L. F.; O'Donnell, J. S.; Killard, A. J. Anal. Bioanal. Chem. 2011, 399, 691-700 10.1007/s00216-010-4314-3
14. Linhardt, R. J. J. Med. Chem. 2003, 46, 2551-2564 10.1021/jm030176m
15. Weitz, J. I. N. Engl. J. Med. 1997, 337, 688-699 10.1056/NEJM199709043371007
16. Ofosu, F. A. Thromb. Haemostasis 2008, 99, 989-990 10.1160/TH08-05-0274
17. Collignon, F.; Frydman, A.; Caplain, H.; Ozoux, M. L.; Le Roux, Y.; Bouthier, J.; Thebault, J. J. Thromb. Haemost. 1995, 73, 630-640
18. Imanari, T.; Toida, T.; Koshiishi, I.; Toyoda, H. J. Chromatogr. A 1996, 720, 275-293 10.1016/0021-9673(95)00338-X
19. Doneanu, C. E.; Chen, W.; Gebler, J. Anal. Chem. 2009, 81, 3485-3499 10.1021/ac802770r
20. Korir, A. K.; Limtiaco, J. F. K.; Gutierrez, S. M.; Larive, C. K. Anal. Chem. 2008, 80, 1297-1306 10.1021/ac702235u
21. Volpi, N.; Galeotti, F.; Yang, B.; Linhardt, R. J. Nat. Protoc. 2014, 9, 541-558 10.1038/nprot.2014.026
22. Li, L.; Zhang, F.; Zaia, J.; Linhardt, R. J. Anal. Chem. 2012, 84, 8822-8829 10.1021/ac302232c
23. Li, G.; Steppich, J.; Wang, Z.; Sun, Y.; Xue, C.; Linhardt, R. J.; Li, L. Anal. Chem. 2014, 86, 6626-6632 10.1021/ac501301v
24. Zhang, Q.; Chen, X.; Zhu, Z.; Zhan, X.; Wu, Y.; Song, L.; Kang, J. Anal. Chem. 2013, 85, 1819-1827 10.1021/ac303185w
25. Zaia, J. Mass Spectrom. Rev. 2004, 23, 161-227 10.1002/mas.10073
26. Zaia, J. Mass Spectrom. Rev. 2009, 28, 254-272 10.1002/mas.20200
27. Huang, Y.; Yu, X.; Mao, Y.; Costello, C. E.; Zaia, J.; Lin, C. Anal. Chem. 2013, 85, 11979-11986 10.1021/ac402931j
28. Maxwell, E.; Tan, Y.; Tan, Y.; Hu, H.; Benson, G.; Aizikov, K.; Conley, S.; Staples, G. O.; Slysz, G. W.; Smith, R. D.; Zaia, J. PLoS One 2012, 7, e45474 10.1371/journal.pone.0045474
29. Jaitly, N.; Mayampurath, A.; Littlefield, K.; Adkins, J. N.; Anderson, G. A.; Smith, R. D. BMC Bioinf. 2009, 10, 87 10.1186/1471-2105-10-87
30. Zaia, J. Mol. Cell. Proteomics 2013, 12, 885-892 10.1074/mcp.R112.026294
31. Jones, C. J.; Beni, S.; Limtiaco, J. F. K.; Langeslay, D. J.; Larive, C. K. Annu. Rev. Anal. Chem. 2011, 4, 439-465 10.1146/annurev-anchem-061010-113911
32. Pursch, M.; Buckenmaier, S. Anal. Chem. 2015, 87, 5310-5317 10.1021/acs.analchem.5b00492