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Volumn 42, Issue 9, 2015, Pages 847-850

New therapies for controlling atopic itch

Author keywords

atopic dermatitis; dorsal root ganglion; itch signal; new therapy; spinal cord

Indexed keywords

ANTIHISTAMINIC AGENT; ATIZORAM; CIM 331 ANTIBODY; CT 327; CYCLOSPORIN; DUPILUMAB; E 6005; EMOLLIENT AGENT; FEXOFENADINE; FLUOCINONIDE; JNJ 39758979; NALFURAFINE; PHOSPHODIESTERASE IV INHIBITOR; PLACEBO; PROTEIN TYROSINE KINASE INHIBITOR; RECEPTOR ANTIBODY; STEROID; TACROLIMUS; UNCLASSIFIED DRUG; ANTIPRURITIC AGENT;

EID: 84940944932     PISSN: 03852407     EISSN: 13468138     Source Type: Journal    
DOI: 10.1111/1346-8138.13060     Document Type: Review
Times cited : (28)

References (40)
  • 1
    • 84896346497 scopus 로고    scopus 로고
    • Epidemiology of atopic dermatitis in Japan
    • Takeuchi S, Esaki H, Furue M,. Epidemiology of atopic dermatitis in Japan. J Dermatol 2014; 41: 200-204.
    • (2014) J Dermatol , vol.41 , pp. 200-204
    • Takeuchi, S.1    Esaki, H.2    Furue, M.3
  • 2
    • 79953074627 scopus 로고    scopus 로고
    • Prevalence of dermatological disorders in Japan: A nationwide, cross-sectional, seasonal, multicenter, hospital-based study
    • Furue M, Yamazaki S, Jimbow K, et al,. Prevalence of dermatological disorders in Japan: a nationwide, cross-sectional, seasonal, multicenter, hospital-based study. J Dermatol 2011; 38: 310-320.
    • (2011) J Dermatol , vol.38 , pp. 310-320
    • Furue, M.1    Yamazaki, S.2    Jimbow, K.3
  • 3
    • 70349617974 scopus 로고    scopus 로고
    • Guidelines for management of atopic dermatitis
    • Saeki H, Furue M, Furukawa F, et al,. Guidelines for management of atopic dermatitis. J Dermatol 2009; 36: 563-577.
    • (2009) J Dermatol , vol.36 , pp. 563-577
    • Saeki, H.1    Furue, M.2    Furukawa, F.3
  • 4
    • 84874473867 scopus 로고    scopus 로고
    • Consensus guidelines for the management of atopic dermatitis: An Asia-Pacific perspective
    • Rubel D, Thirumoorthy T, Soebaryo RW, et al,. Consensus guidelines for the management of atopic dermatitis: an Asia-Pacific perspective. J Dermatol 2013; 40: 160-171.
    • (2013) J Dermatol , vol.40 , pp. 160-171
    • Rubel, D.1    Thirumoorthy, T.2    Soebaryo, R.W.3
  • 5
    • 84884131951 scopus 로고    scopus 로고
    • Neural processing of itch
    • Akiyama T, Carstens E,. Neural processing of itch. Neuroscience 2013; 250: 697-714.
    • (2013) Neuroscience , vol.250 , pp. 697-714
    • Akiyama, T.1    Carstens, E.2
  • 6
    • 84928155371 scopus 로고    scopus 로고
    • Topical TrkA kinase inhibitor CT327 is an effective, novel therapy for the treatment of pruritus due to psoriasis: Results from experimental studies, and efficacy and safety of CT327 in a phase 2b clinical trial in patients with psoriasis
    • Roblin D, Yosipovitch G, Boyce B, et al,. Topical TrkA kinase inhibitor CT327 is an effective, novel therapy for the treatment of pruritus due to psoriasis: results from experimental studies, and efficacy and safety of CT327 in a phase 2b clinical trial in patients with psoriasis. Acta Derm Venereol 2015; 95: 542-548.
    • (2015) Acta Derm Venereol , vol.95 , pp. 542-548
    • Roblin, D.1    Yosipovitch, G.2    Boyce, B.3
  • 7
    • 72149094312 scopus 로고    scopus 로고
    • Collared mice: A model to assess the effects of scratching
    • Takeuchi S, Yasukawa F, Furue M, Katz SI,. Collared mice: a model to assess the effects of scratching. J Dermatol Sci 2010; 57: 44-50.
    • (2010) J Dermatol Sci , vol.57 , pp. 44-50
    • Takeuchi, S.1    Yasukawa, F.2    Furue, M.3    Katz, S.I.4
  • 8
    • 23744450896 scopus 로고    scopus 로고
    • The price of pruritus: Sleep disturbance and cosleeping in atopic dermatitis
    • Chamlin SL, Mattson CL, Frieden IJ, et al,. The price of pruritus: sleep disturbance and cosleeping in atopic dermatitis. Arch Pediatr Adolesc Med 2005; 159: 745-750.
    • (2005) Arch Pediatr Adolesc Med , vol.159 , pp. 745-750
    • Chamlin, S.L.1    Mattson, C.L.2    Frieden, I.J.3
  • 9
    • 84896388104 scopus 로고    scopus 로고
    • Novel acoustic evaluation system for scratching behavior in itching dermatitis: Rapid and accurate analysis for nocturnal scratching of atopic dermatitis patients
    • Noro Y, Omoto Y, Umeda K, et al,. Novel acoustic evaluation system for scratching behavior in itching dermatitis: rapid and accurate analysis for nocturnal scratching of atopic dermatitis patients. J Dermatol 2014; 41: 233-238.
    • (2014) J Dermatol , vol.41 , pp. 233-238
    • Noro, Y.1    Omoto, Y.2    Umeda, K.3
  • 10
    • 84896321226 scopus 로고    scopus 로고
    • Itch and nerve fibers with special reference to atopic dermatitis: Therapeutic implications
    • Tominaga M, Takamori K,. Itch and nerve fibers with special reference to atopic dermatitis: therapeutic implications. J Dermatol 2014; 41: 205-212.
    • (2014) J Dermatol , vol.41 , pp. 205-212
    • Tominaga, M.1    Takamori, K.2
  • 12
    • 77954429597 scopus 로고    scopus 로고
    • Responsiveness of C neurons in rat dorsal root ganglion to 5-hydroxytryptamine-induced pruritic stimuli in vivo
    • Hachisuka J, Furue H, Furue M, Yoshimura M,. Responsiveness of C neurons in rat dorsal root ganglion to 5-hydroxytryptamine-induced pruritic stimuli in vivo. J Neurophysiol 2010; 104: 271-279.
    • (2010) J Neurophysiol , vol.104 , pp. 271-279
    • Hachisuka, J.1    Furue, H.2    Furue, M.3    Yoshimura, M.4
  • 13
    • 84892815698 scopus 로고    scopus 로고
    • Pruritus: Do Aδ fibers play a role?
    • Aynacbox Drawings Light Down And Left O. Dincer N.
    • Tekatas A, Arican O, Guler S, Aynacbox drawings light down and left O, Dincer N,. Pruritus: do Aδ fibers play a role? J Dermatol 2014; 41: 98-101.
    • (2014) J Dermatol , vol.41 , pp. 98-101
    • Tekatas, A.1    Arican, O.2    Guler, S.3
  • 14
    • 72249113172 scopus 로고    scopus 로고
    • Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus
    • Liu Q, Tang Z, Surdenikova L, et al,. Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus. Cell 2009; 139: 1353-1365.
    • (2009) Cell , vol.139 , pp. 1353-1365
    • Liu, Q.1    Tang, Z.2    Surdenikova, L.3
  • 15
    • 77957891302 scopus 로고    scopus 로고
    • Enhanced scratching evoked by PAR-2 agonist and 5-HT but not histamine in a mouse model of chronic dry skin itch
    • Akiyama T, Carstens MI, Carstens E,. Enhanced scratching evoked by PAR-2 agonist and 5-HT but not histamine in a mouse model of chronic dry skin itch. Pain 2010; 151: 378-383.
    • (2010) Pain , vol.151 , pp. 378-383
    • Akiyama, T.1    Carstens, M.I.2    Carstens, E.3
  • 16
    • 34547726181 scopus 로고    scopus 로고
    • A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord
    • Sun YG, Chen ZF,. A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord. Nature 2007; 448: 700-703.
    • (2007) Nature , vol.448 , pp. 700-703
    • Sun, Y.G.1    Chen, Z.F.2
  • 18
    • 84877939975 scopus 로고    scopus 로고
    • The cells and circuitry for itch responses in mice
    • Mishra SK, Hoon MA,. The cells and circuitry for itch responses in mice. Science 2013; 340: 968-971.
    • (2013) Science , vol.340 , pp. 968-971
    • Mishra, S.K.1    Hoon, M.A.2
  • 19
    • 84891825227 scopus 로고    scopus 로고
    • Roles of glutamate, substance P, and gastrin-releasing peptide as spinal neurotransmitters of histaminergic and nonhistaminergic itch
    • Akiyama T, Tominaga M, Takamori K, Carstens MI, Carstens E,. Roles of glutamate, substance P, and gastrin-releasing peptide as spinal neurotransmitters of histaminergic and nonhistaminergic itch. Pain 2014; 155: 80-92.
    • (2014) Pain , vol.155 , pp. 80-92
    • Akiyama, T.1    Tominaga, M.2    Takamori, K.3    Carstens, M.I.4    Carstens, E.5
  • 20
    • 84923047903 scopus 로고    scopus 로고
    • Expression of gastrin-releasing peptide by excitatory interneurons in the mouse superficial dorsal horn
    • Gutierrez-Mecinas M, Watanabe M, Todd AJ,. Expression of gastrin-releasing peptide by excitatory interneurons in the mouse superficial dorsal horn. Mol Pain 2014; 10: 79. doi: 10.1186/1744-8069-10-79.
    • (2014) Mol Pain , vol.10 , pp. 79
    • Gutierrez-Mecinas, M.1    Watanabe, M.2    Todd, A.J.3
  • 21
    • 84920972659 scopus 로고    scopus 로고
    • Primary afferent and spinal cord expression of gastrin-releasing peptide: Message, protein, and antibody concerns
    • Solorzano C, Villafuerte D, Meda K, et al,. Primary afferent and spinal cord expression of gastrin-releasing peptide: message, protein, and antibody concerns. J Neurosci 2015; 35: 648-657.
    • (2015) J Neurosci , vol.35 , pp. 648-657
    • Solorzano, C.1    Villafuerte, D.2    Meda, K.3
  • 22
    • 84925278477 scopus 로고    scopus 로고
    • Targeted ablation, silencing, and activation establish glycinergic dorsal horn neurons as key components of a spinal gate for pain and itch
    • Foster E, Wildner H, Tudeau L, et al,. Targeted ablation, silencing, and activation establish glycinergic dorsal horn neurons as key components of a spinal gate for pain and itch. Neuron 2015; 85: 1289-1304.
    • (2015) Neuron , vol.85 , pp. 1289-1304
    • Foster, E.1    Wildner, H.2    Tudeau, L.3
  • 23
    • 79957886504 scopus 로고    scopus 로고
    • Questionnaire survey of the efficacy of emollients for adult patients with atopic dermatitis
    • Kawakami T, Soma Y,. Questionnaire survey of the efficacy of emollients for adult patients with atopic dermatitis. J Dermatol 2011; 38: 531-535.
    • (2011) J Dermatol , vol.38 , pp. 531-535
    • Kawakami, T.1    Soma, Y.2
  • 24
    • 79952706744 scopus 로고    scopus 로고
    • Topical application of emollients prevents dry skin-inducible intraepidermal nerve growth in acetone-treated mice
    • Kamo A, Tominaga M, Negi O, Tengara S, Ogawa H, Takamori K,. Topical application of emollients prevents dry skin-inducible intraepidermal nerve growth in acetone-treated mice. J Dermatol Sci 2011; 62: 64-66.
    • (2011) J Dermatol Sci , vol.62 , pp. 64-66
    • Kamo, A.1    Tominaga, M.2    Negi, O.3    Tengara, S.4    Ogawa, H.5    Takamori, K.6
  • 25
    • 79956357035 scopus 로고    scopus 로고
    • Effects of a novel formulation of fluocinonide 0.1% cream on skin barrier function in atopic dermatitis
    • Woods MT, Brown PA, Baig-Lewis SF, Simpson EL,. Effects of a novel formulation of fluocinonide 0.1% cream on skin barrier function in atopic dermatitis. J Drugs Dermatol 2011; 10: 171-176.
    • (2011) J Drugs Dermatol , vol.10 , pp. 171-176
    • Woods, M.T.1    Brown, P.A.2    Baig-Lewis, S.F.3    Simpson, E.L.4
  • 26
    • 84860643529 scopus 로고    scopus 로고
    • A randomized, open-label, multicenter trial of topical tacrolimus for the treatment of pruritis in patients with atopic dermatitis
    • Takeuchi S, Saeki H, Tokunaga S, et al,. A randomized, open-label, multicenter trial of topical tacrolimus for the treatment of pruritis in patients with atopic dermatitis. Ann Dermatol 2012; 24: 144-150.
    • (2012) Ann Dermatol , vol.24 , pp. 144-150
    • Takeuchi, S.1    Saeki, H.2    Tokunaga, S.3
  • 27
    • 0038346446 scopus 로고    scopus 로고
    • Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study
    • Kawashima M, Tango T, Noguchi T, Inagi M, Nakagawa H, Harada S,. Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study. Br J Dermatol 2003; 148: 1212-1221.
    • (2003) Br J Dermatol , vol.148 , pp. 1212-1221
    • Kawashima, M.1    Tango, T.2    Noguchi, T.3    Inagi, M.4    Nakagawa, H.5    Harada, S.6
  • 28
    • 84856013399 scopus 로고    scopus 로고
    • Effects of cyclosporine on pruritus and serum IL-31 levels in patients with atopic dermatitis
    • Otsuka A, Tanioka M, Nakagawa Y, et al,. Effects of cyclosporine on pruritus and serum IL-31 levels in patients with atopic dermatitis. Eur J Dermatol 2011; 21: 816-817.
    • (2011) Eur J Dermatol , vol.21 , pp. 816-817
    • Otsuka, A.1    Tanioka, M.2    Nakagawa, Y.3
  • 29
    • 84903887689 scopus 로고    scopus 로고
    • Dupilumab treatment in adults with moderate-to-severe atopic dermatitis
    • Beck LA, Thaçi D, Hamilton JD, et al,. Dupilumab treatment in adults with moderate-to-severe atopic dermatitis. N Engl J Med 2014; 371: 130-139.
    • (2014) N Engl J Med , vol.371 , pp. 130-139
    • Beck, L.A.1    Thaçi, D.2    Hamilton, J.D.3
  • 30
    • 84896344225 scopus 로고    scopus 로고
    • Thymus and activation-regulated chemokine as a clinical biomarker in atopic dermatitis
    • Kataoka Y,. Thymus and activation-regulated chemokine as a clinical biomarker in atopic dermatitis. J Dermatol 2014; 41: 221-229.
    • (2014) J Dermatol , vol.41 , pp. 221-229
    • Kataoka, Y.1
  • 31
    • 84922696048 scopus 로고    scopus 로고
    • Phase 2a, randomized, double-blind, placebo-controlled, multicenter, parallel-group study of a H4R-antagonist (JNJ-39758979) in Japanese adults with moderate atopic dermatitis
    • Murata Y, Song M, Kikuchi H, et al,. Phase 2a, randomized, double-blind, placebo-controlled, multicenter, parallel-group study of a H4R-antagonist (JNJ-39758979) in Japanese adults with moderate atopic dermatitis. J Dermatol 2015; 42: 129-139.
    • (2015) J Dermatol , vol.42 , pp. 129-139
    • Murata, Y.1    Song, M.2    Kikuchi, H.3
  • 32
    • 0030056483 scopus 로고    scopus 로고
    • Type 4 phosphodiesterase inhibitors have clinical and in vitro anti-inflammatory effects in atopic dermatitis
    • Hanifin JM, Chan SC, Cheng JB, et al,. Type 4 phosphodiesterase inhibitors have clinical and in vitro anti-inflammatory effects in atopic dermatitis. J Invest Dermatol 1996; 107: 51-56.
    • (1996) J Invest Dermatol , vol.107 , pp. 51-56
    • Hanifin, J.M.1    Chan, S.C.2    Cheng, J.B.3
  • 33
    • 84903814479 scopus 로고    scopus 로고
    • Safety and efficacy of topical E6005, a phosphodiesterase 4 inhibitor, in Japanese adult patients with atopic dermatitis: Results of a randomized, vehicle-controlled, multicenter clinical trial
    • Furue M, Kitahara Y, Akama H, et al,. Safety and efficacy of topical E6005, a phosphodiesterase 4 inhibitor, in Japanese adult patients with atopic dermatitis: results of a randomized, vehicle-controlled, multicenter clinical trial. J Dermatol 2014; 41: 577-585.
    • (2014) J Dermatol , vol.41 , pp. 577-585
    • Furue, M.1    Kitahara, Y.2    Akama, H.3
  • 34
    • 84901193124 scopus 로고    scopus 로고
    • A review of phosphodiesterase-inhibition and the potential role for phosphodiesterase 4-inhibitors in clinical dermatology
    • Moustafa F, Feldman SR,. A review of phosphodiesterase-inhibition and the potential role for phosphodiesterase 4-inhibitors in clinical dermatology. Dermatol Online J 2014; 20: 22608.
    • (2014) Dermatol Online J , vol.20 , pp. 22608
    • Moustafa, F.1    Feldman, S.R.2
  • 35
    • 84895065194 scopus 로고    scopus 로고
    • A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: Involvement of TRPV1 and TRPA1
    • Cevikbas F, Wang X, Akiyama T, et al,. A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: involvement of TRPV1 and TRPA1. J Allergy Clin Immunol 2014; 133: 448-460.
    • (2014) J Allergy Clin Immunol , vol.133 , pp. 448-460
    • Cevikbas, F.1    Wang, X.2    Akiyama, T.3
  • 36
    • 84892727105 scopus 로고    scopus 로고
    • Interleukin-31 does not induce immediate itch in atopic dermatitis patients and healthy controls after skin challenge
    • Hawro T, Saluja R, Weller K, Altrichter S, Metz M, Maurer M,. Interleukin-31 does not induce immediate itch in atopic dermatitis patients and healthy controls after skin challenge. Allergy 2014; 69: 113-117.
    • (2014) Allergy , vol.69 , pp. 113-117
    • Hawro, T.1    Saluja, R.2    Weller, K.3    Altrichter, S.4    Metz, M.5    Maurer, M.6
  • 37
    • 84904263700 scopus 로고    scopus 로고
    • Human Th2 but not Th9 cells release IL-31 in a STAT6/NF-κB-dependent way
    • Maier E, Werner D, Duschl A, Bohle B, Horejs-Hoeck J,. Human Th2 but not Th9 cells release IL-31 in a STAT6/NF-κB-dependent way. J Immunol 2014; 193: 645-654.
    • (2014) J Immunol , vol.193 , pp. 645-654
    • Maier, E.1    Werner, D.2    Duschl, A.3    Bohle, B.4    Horejs-Hoeck, J.5
  • 38
    • 77950267997 scopus 로고    scopus 로고
    • Effect of a novel kappa-receptor agonist, nalfurafine hydrochloride, on severe itch in 337 haemodialysis patients: A Phase III, randomized, double-blind, placebo-controlled study
    • Kumagai H, Ebata T, Takamori K, Muramatsu T, Nakamoto H, Suzuki H,. Effect of a novel kappa-receptor agonist, nalfurafine hydrochloride, on severe itch in 337 haemodialysis patients: a Phase III, randomized, double-blind, placebo-controlled study. Nephrol Dial Transplant 2010; 25: 1251-1257.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 1251-1257
    • Kumagai, H.1    Ebata, T.2    Takamori, K.3    Muramatsu, T.4    Nakamoto, H.5    Suzuki, H.6
  • 39
    • 84928007739 scopus 로고    scopus 로고
    • Nalfurafine suppresses pruritogen- and touch-evoked scratching behavior in models of acute and chronic itch in mice
    • Akiyama T, Carstens MI, Piecha D, Steppan S, Carstens E,. Nalfurafine suppresses pruritogen- and touch-evoked scratching behavior in models of acute and chronic itch in mice. Acta Derm Venereol 2015; 95: 147-150.
    • (2015) Acta Derm Venereol , vol.95 , pp. 147-150
    • Akiyama, T.1    Carstens, M.I.2    Piecha, D.3    Steppan, S.4    Carstens, E.5
  • 40
    • 84896365268 scopus 로고    scopus 로고
    • Genome-wide association studies of atopic dermatitis
    • Tamari M, Hirota T,. Genome-wide association studies of atopic dermatitis. J Dermatol 2014; 41: 213-220.
    • (2014) J Dermatol , vol.41 , pp. 213-220
    • Tamari, M.1    Hirota, T.2


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