Maternal depression and child oxytocin response; Moderation by maternal oxytocin and relational behavior

Depression and Anxiety

Volumn 32, Issue 9, 2015, Pages 635-646

  Pratt, Maayan ^a   Apter Levi, Yael ^a   Vakart, Adam ^a   Feldman, Michal ^a   Fishman, Ruth ^a   Feldman, Tamar ^a   Zagoory Sharon, Orna ^a   Feldman, Ruth ^a  

^a BAR ILAN UNIVERSITY   (Israel)

Author keywords

child psychopathology; cross generation transmission; longitudinal studies; maternal depression; mother child interaction; oxytocin

Indexed keywords

OXYTOCIN;

ADULT; ANXIETY; ARTICLE; CHILD BEHAVIOR; CHILD PARENT RELATION; COHORT ANALYSIS; CONTROLLED STUDY; COPING BEHAVIOR; DRUG RESPONSE; DSM-IV; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MENTAL DISEASE; MOTHER CHILD RELATION; PRIORITY JOURNAL; PSYCHOSOCIAL WITHDRAWAL; PUERPERAL DEPRESSION; SOCIAL BEHAVIOR; SOCIAL INTERACTION; SOCIAL INTERACTION ANXIETY SCALE; WELLBEING; CASE CONTROL STUDY; CHILD; CHRONIC DISEASE; DEPRESSION; DEPRESSION, POSTPARTUM; INFANT; MALE; MATERNAL BEHAVIOR; MOTHER; NEWBORN; PRESCHOOL CHILD; PSYCHOLOGY; TOUCH; URINE;

ADULT; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CHRONIC DISEASE; DEPRESSION; DEPRESSION, POSTPARTUM; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; MALE; MATERNAL BEHAVIOR; MOTHER-CHILD RELATIONS; MOTHERS; OXYTOCIN; SOCIAL BEHAVIOR; TOUCH;

EID: 84940888667     PISSN: 10914269     EISSN: 15206394     Source Type: Journal    
DOI: 10.1002/da.22392     Document Type: Article

References (89)

1. Noble RE,. Depression in women. Metabolism 2005; 54: 49-52.
2. Dawson G, Ashman SB, Panagiotides H, et al., Preschool outcomes of children of depressed mothers: role of maternal behavior, contextual risk, and children's brain activity. Child Dev 2003; 74: 1158-1175.
3. Kujawa AJ, Torpey D, Kim J, et al., Attentional biases for emotional faces in young children of mothers with chronic or recurrent depression. J Abnorm Child Psychol 2011; 39: 125-35.
4. Gravener JA, Rogosch FA, Oshri A, et al., The relations among maternal depressive disorder, maternal expressed emotion, and toddler behavior problems and attachment. J Abnorm Child Psychol 2012; 40: 803-813.
5. Goodman SH, Rouse MH, Connell AM, et al., Maternal depression and child psychopathology: a meta-analytic review. Clin Child Fam Psychol Rev 2011; 14: 1-27.
6. Suveg C., Shaffer A., Morelen D, et al., Links between maternal and child psychopathology symptoms: mediation through child emotion regulation and moderation through maternal behavior. Child Psychiatry Hum Dev 2011; 42: 507-520.
7. Murray L, Arteche A, Fearon P, et al., Maternal postnatal depression and the development of depression in offspring up to 16 years of age. J Am Acad Child Adolesc Psychiatry 2011; 50: 460-470.
8. Silk JS, Shaw DS, Prout JT, et al., Socialization of emotion and offspring internalizing symptoms in mothers with childhood-onset depression. J Appl Dev Psychol 2011; 32: 127-136.
9. Halligan SL, Murray L, Martins C, et al., Maternal depression and psychiatric outcomes in adolescent offspring: a 13-year longitudinal study. J Affect Disord 2007; 97: 145-154.
10. Kam C-M, Greenberg MT, Bierman KL, et al., Maternal depressive symptoms and child social preference during the early school years: mediation by maternal warmth and child emotion regulation. J Abnorm Child Psychol 2011; 39: 365-377.
11. Stein A, Craske MG, Lehtonen A, et al., Maternal cognitions and mother-infant interaction in postnatal depression and generalized anxiety disorder. J Abnorm Psychol 2012; 121: 795-809.
12. Beebe B, Lachmann F, Jaffe J, et al., Maternal postpartum depressive symptoms and 4-month mother-infant interaction. Psychoanal Psychol 2012; 29: 383-407.
13. Væver M. S, Krogh MT, Smith-Nielsen J, et al., Measuring spatial proximity in mother-infant interaction: a kinematic approach for an examination of the effects of maternal postpartum depression. Infant Behav Dev 2013; 36: 427-431.
14. Edhborg M, Nasreen H-E, Kabir ZN,. Impact of postpartum depressive and anxiety symptoms on mothers' emotional tie to their infants 2-3 months postpartum: a population-based study from rural Bangladesh. Arch Womens Ment Health 2011; 14: 307-316.
15. Carter CS., Oxytocin pathways and the evolution of human behavior. Annu Rev Psychol 2014; 65: 17-39.
16. Feldman R., Parent-infant synchrony: a biobehavioral model of mutual influences in the formation of affiliative bonds. Monogr. Soc. Res. Child Dev. 2012; 77: 42-51.
17. Cameron NM, Shahrokh D, Del Corpo A, et al., Epigenetic programming of phenotypic variations in reproductive strategies in the rat through maternal care. J Neuroendocrinol 2008; 20: 795-801.
18. Maestripieri D, Hoffman CL, Anderson GM, et al., Mother-infant interactions in free-ranging rhesus macaques: relationships between physiological and behavioral variables. Physiol Behav 2009; 96: 613-619.
19. Feldman R, Gordon I, Zagoory-Sharon O,. The cross-generation transmission of oxytocin in humans. Horm. Behav. 2010; 58: 669-676.
20. Weisman O, Zagoory-Sharon O, Feldman R,. Oxytocin administration to parent enhances infant physiological and behavioral readiness for social engagement. Biol Psychiatry 2012; 72: 982-989.
21. Uvnas-Moberg K,. Physiological and endocrine effects of social contact. Ann N Y Acad Sci 1997; 807: 146-163.
22. Brunton PJ, Russell JA,. The expectant brain: adapting for motherhood. Nat Rev Neurosci 2008; 9: 11-25.
23. Feldman R, Zagoory-Sharon O, Weisman O, et al., Sensitive parenting is associated with plasma oxytocin and polymorphisms in the OXTR and CD38 genes. Biol Psychiatry 2012; 72: 175-181.
24. Bakermans-Kranenburg MJ, van Ijzendoorn MH,. Oxytocin receptor (OXTR) and serotonin transporter (5-HTT) genes associated with observed parenting. Soc Cogn Affect Neurosci 2008; 3: 128-134.
25. Feldman R, Gordon I, Zagoory-Sharon O,. Maternal and paternal plasma, salivary, and urinary oxytocin and parent-infant synchrony: considering stress and affiliation components of human bonding. Dev Sci 2011; 14: 752-761.
26. Galbally M, Lewis AJ, Ijzendoorn MVan, et al., The role of oxytocin in mother-infant relations: a systematic review of human studies. Harv Rev Psychiatry 2011; 19: 1-14.
27. Naber F, van Ijzendoorn MH, Deschamps P, et al., Intranasal oxytocin increases fathers' observed responsiveness during play with their children: a double-blind within-subject experiment. Psychoneuroendocrinology 2010; 35: 1583-1586.
28. Feldman R, Gordon I, Schneiderman I, et al., Natural variations in maternal and paternal care are associated with systematic changes in oxytocin following parent-infant contact. Psychoneuroendocrinology 2010; 35: 1133-1141.
29. Meaney MJ,. Maternal care, gene expretion, and the transmission of individual differences in stress reactivity across generation. Annu Rev Neurosci 2001; 24: 1162-1192.
30. Meaney MJ,. Epigenetics and the biological definition of gene x environment interactions. Child Dev 2010; 81: 41-79.
31. Feldman R, Gordon I, Influs M, et al., Parental oxytocin and early caregiving jointly shape children's oxytocin response and social reciprocity. Neuropsychopharmacology 2013; 38: 1154-1162.
32. Elmadih A, Wan MW, Numan M, et al., Does oxytocin modulate variation in maternal caregiving in healthy new mothers? Brain Res 2014; 1580: 143-150.
33. Ludwig M, Leng G,. Dendritic peptide release and peptide-dependent behaviours. Nat Rev Neurosci 2006; 7: 126-136.
34. Zheng JJ, Li S-J, Zhang X-D, et al., Oxytocin mediates early experience-dependent cross-modal plasticity in the sensory cortices. Nat. Neurosci. 2014; 17: 391-399.
35. Scantamburlo G, Hansenne M, Fuchs S, et al., Plasma oxytocin levels and anxiety in patients with major depression. Psychoneuroendocrinology 2007; 32: 407-410.
36. Garcia FD, Coquerel Q, Kiive E, et al., Autoantibodies reacting with vasopressin and oxytocin in relation to cortisol secretion in mild and moderate depression. Prog Neuropsychopharmacol Biol Psychiatry 2011; 35: 118-125.
37. Yuen KW, Garner JP, Carson DS, et al., Plasma oxytocin concentrations are lower in depressed vs. healthy control women and are independent of cortisol. J Psychiatr Res 2014; 51: 30-36.
38. Cox EQ, Stuebe a, Pearson B, et al., Oxytocin and HPA stress axis reactivity in postpartum women. Psychoneuroendocrinology 2015; 55: 164-172.
39. Garfield L, Giurgescu C, Carter CS, et al., Depressive symptoms in the second trimester relate to low oxytocin levels in African-American women: a pilot study. Arch Womens Ment Health 2015; 18: 123-129.
40. Scantamburlo G, Hansenne M, Fuchs S, et al., AVP- and OT-neurophysins response to apomorphine and clonidine in major depression. Psychoneuroendocrinology 2005; 30: 839-845.
41. Ozsoy S, Esel E, Kula M,. Serum oxytocin levels in patients with depression and the effects of gender and antidepressant treatment. Psychiatry Res 2009; 169: 249-252.
42. Frasch A, Zetzsche T, Steiger A, et al., Reduction of plasma oxytocin levels in patients suffering from major depression. Adv Exp Med Biol 1995; 395: 257-258.
43. Parker KJ, Kenna Ha, Zeitzer JM, et al., Preliminary evidence that plasma oxytocin levels are elevated in major depression. Psychiatry Res. 2010; 178: 359-362.
44. Cyranowski JM, Hofkens TL, Frank E, et al., Evidence of dysregulated peripheral oxytocin release among depressed women. Psychosom Med 2008; 70: 967-975.
45. Jobst A, Sabass L, Palagyi A, et al., Effects of social exclusion on emotions and oxytocin and cortisol levels in patients with chronic depression. J Psychiatr Res 2015; 60: 170-177.
46. Pincus D, Kose S, Arana A, et al., Inverse effects of oxytocin on attributing mental activity to others in depressed and healthy subjects: a double-blind placebo controlled FMRI study. Front Psychiatry 2010; 1:134: 1-10.
47. Apter-Levi Y, Zagoory-Sharon O, Feldman R,. Oxytocin and vasopressin support distinct configurations of social synchrony. Brain Res 2013; 1580: 124-132.
48. Apter-Levy Y, Feldman M, Vakart A, et al., Impact of maternal depression across the first 6 years of life on the child' s mental health, social engagement, and empathy: the moderating role of oxytocin. Am J Psychiatry 2013; 170: 1161-1168.
49. Stuebe AM, Grewen K, Meltzer-Brody S,. Association between maternal mood and oxytocin response to breastfeeding. J Womens Health (Larchmt) 2013; 22: 352-361.
50. Zelkowitz P, Gold I, Feeley N, et al., Psychosocial stress moderates the relationships between oxytocin, perinatal depression, and maternal behavior. Horm Behav 2014; 66: 351-360.
51. Skrundz M, Bolten M, Nast I, et al., Plasma oxytocin concentration during pregnancy is associated with development of postpartum depression. Neuropsychopharmacology 2011; 36: 1886-1893.
52. Riem MME, Pieper S, Out D, et al., Oxytocin receptor gene and depressive symptoms associated with physiological reactivity to infant crying. Soc Cogn Affect Neurosci 2011; 6: 294-300.
53. Cohn JF, Matias R, Tronick EZ, et al., Face-to-face interactions of depressed mothers and their infants. New Dir Child Adolesc Dev 1986; 1986: 31-45.
54. Feldman R, Granat A, Pariente C, et al., Maternal depression and anxiety across the postpartum year and infant social engagement, fear regulation, and stress reactivity. J Am Acad Child Adolesc Psychiatry 2009; 48: 919-927.
55. Lovejoy MC, Graczyk PA, O'Hare E, et al., Maternal depression and parenting behavior. Clin Psychol Rev 2000; 20: 561-592.
56. Milne L, Greenway P, Guedeney A, et al., Long term developmental impact of social withdrawal in infants. Infant Behav Dev 2009; 32: 159-166.
57. Gotlib IH, Joormann J, Foland-Ross LC,. Understanding Familial Risk for Depression: A 25-Year Perspective. Perspect Psychol Sci 2014; 9: 94-108.
58. Weisman O, Zagoory-Sharon O, Feldman R,. Oxytocin administration alters HPA reactivity in the context of parent-infant interaction. Eur Neuropsychopharmacol 2013; 23: 1724-1731.
59. Amico JA, Tenicela R, Robinson AG,. Neurohypophysial hormones in cerebrospinal fluid of adults: absence of arginine vasotocin and of a diurnal rhythm of arginine vasopressin. J Clin Endocrinol Metab 1985; 61: 794-798.
60. Amico JA, Tenicela R, Johnston J, et al., A time-dependent peak of oxytocin exists in cerebrospinal fluid but not in plasma of humans. J Clin Endocrinol Metab 1983; 57: 947-51.
61. First M, Spitzer R, Gibbon M, et al., Structured Clinical Interview for DSM-IV Axis I Disorders-Clinician Version (SCID-CV). Washington, DC: American Psychiatric Press; 1997.
62. Goodman R, Ford T, Richards H, et al., The development and well-being assessment: description and initial validation of an integrated assessment of child and adolescent psychopathology. J Child Psychol Psychiatry 2000; 41: 645-655.
63. Mansbach-Kleinfeld I, Apter A, Farbstein I, et al., A population-based psychometric validation study of the strengths and difficulties questionnaire-hebrew version. Front Psychiatry 2010; 1:151: 1-12.
64. Feldman R,. On the origins of background emotions: from affect synchrony to symbolic expression. Emotion 2007; 7: 601-611.
65. Feldman R,. In:, Mayes, LC, and, Lewis, M, editors. The Cambridge handbook of environment in human development. New York, NY, Cambridge University Press; 2012: 535-1102.
66. Dollberg D, Feldman R, Keren M, et al., Sustained withdrawal behavior in clinic-referred and nonreferred infants. Infant Ment Health J 2006; 27: 292-309.
67. Aiken LS, West SG., Multiple Regression: Testing and Interpreting Interactions. Sage Thousand Oaks, CA; 1991.
68. Brown TA, Campbell LA, Lehman CL, et al., Current and lifetime comorbidity of the DSM-IV anxiety and mood disorders in a large clinical sample. J Abnorm Psychol 2001; 110: 585-599.
69. Cochran DM, Fallon D, Hill M, et al., The role of oxytocin in psychiatric disorders: a review of biological and therapeutic research findings. Harv Rev Psychiatry 2014; 21: 219-47.
70. Fries AB. W, Ziegler TE, Kurian JR, et al., Early experience in humans is associated with changes in neuropeptides critical for regulating social behavior. Proc Natl Acad Sci U S A 2005; 102: 17237-17240.
71. Seltzer LJ, Ziegler T, Connolly MJ, et al., Stress-induced elevation of oxytocin in maltreated children: evolution, neurodevelopment, and social behavior. Child Dev 2013; 85: 501-512.
72. Seltzer LJ, Ziegler TE, Pollak SD,. Social vocalizations can release oxytocin in humans. Proc Biol Sci 2010; 277: 2661-2666.
73. Chou C, DiGiovanni SR, Luther A, et al., Oxytocin as an antidiuretic hormone. II. Role of V2 vasopressin receptor. Am J Physiol Fluid Electrolyte Physiol 1995; 38: F78-F85.
74. Holstege G., Micturition and the soul. J Comp Neurol 2005; 493: 15-20.
75. Feldman R, Bamberger E, Kanat-Maymon Y,. Parent-specific reciprocity from infancy to adolescence shapes children's social competence and dialogical skills. Attach Hum Dev 2013; 15: 407-423.
76. Burgdorf J, Panksepp J,. The neurobiology of positive emotions. Neurosci Biobehav Rev 2006; 30: 173-187.
77. Mah BL, Van Ijzendoorn MH, Smith R, et al., Oxytocin in postnatally depressed mothers: its influence on mood and expressed emotion. Prog Neuropsychopharmacol Biol Psychiatry 2013; 40: 267-272.
78. Kim S, Soeken TA, Cromer SJ, et al., Oxytocin and postpartum depression: delivering on what's known and what's not. Brain Res 2014; 1580: 219-232.
79. Feldman R, Rosenthal Z, Eidelman, AI,. Maternal-preterm skin-to-skin contact enhances child physiologic organization and cognitive control across the first 10 years of life. Biol Psychiatry 2014; 75: 56-64.
80. Feldman R, Weller A, Zagoory-Sharon O, et al., Evidence for a neuroendocrinological foundation of human affiliation: plasma oxytocin levels across pregnancy and the postpartum period predict mother-infant bonding. Psychol Sci 2007; 18: 965-970.
81. McCullough ME, Churchland PS, Mendez AJ,. Problems with measuring peripheral oxytocin: can the data on oxytocin and human behavior be trusted? Neurosci Biobehav Rev 2013; 37: 1485-1492.
82. Crockford C, Deschner T, Ziegler TE, et al., Endogenous peripheral oxytocin measures can give insight into the dynamics of social relationships: a review. Front Behav Neurosci 2014; 8:68: 1-14.
83. Neumann ID, Maloumby R, Beiderbeck DI, et al., Increased brain and plasma oxytocin after nasal and peripheral administration in rats and mice. Psychoneuroendocrinology 2013; 38: 1985-1993.
84. Nagasawa M, Mitsui S, En S, et al., Oxytocin-gaze positive loop and the coevolution of human-dog bonds. Science 2015; 348: 333-336.
85. Bick J, Dozier M, Bernard K, et al., Foster mother-infant bonding: associations between foster mothers' oxytocin production, electrophysiological brain activity, feelings of commitment, and caregiving quality. Child Dev 2013; 84: 826-840.
86. Saito A, Hamada H, Kikusui T, et al., Urinary oxytocin positively correlates with performance in facial visual search in unmarried males, without specific reaction to infant face. Front Neurosci 2014; 8:217: 1-7.
87. Gregory R, Cheng H, Rupp Ha, et al., Oxytocin increases VTA activation to infant and sexual stimuli in nulliparous and postpartum women. Horm Behav 2015; 69: 82-88.
88. Schneiderman I, Zagoory-Sharon O, Leckman JF, et al., Oxytocin during the initial stages of romantic attachment: relations to couples' interactive reciprocity. Psychoneuroendocrinology 2012; 37: 1277-1285.
89. Schneiderman I, Kanat-Maymon Y, Zagoory-Sharon O, et al., Mutual influences between partners' hormones shape conflict dialog and relationship duration at the initiation of romantic love. Soc Neurosci 2014; 9: 337-351.