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Volumn 15, Issue 1, 2015, Pages

ER, PgR, Ki67, p27Kip1, and histological grade as predictors of pathological complete response in patients with HER2-positive breast cancer receiving neoadjuvant chemotherapy using taxanes followed by fluorouracil, epirubicin, and cyclophosphamide concomitant with trastuzumab

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLOPHOSPHAMIDE; DOCETAXEL; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIRUBICIN; ESTROGEN RECEPTOR; FLUOROURACIL; KI 67 ANTIGEN; PACLITAXEL; PROGESTERONE RECEPTOR; TRASTUZUMAB; ANTINEOPLASTIC AGENT; ERBB2 PROTEIN, HUMAN; TAXOID; TUMOR MARKER;

EID: 84940882770     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-015-1641-y     Document Type: Article
Times cited : (52)

References (39)
  • 2
    • 33646445341 scopus 로고    scopus 로고
    • Sequential preoperative or postoperative docetaxel added to preoperative doxorubicin plus cyclophosphamide for operable breast cancer: National Surgical Adjuvant Breast and Bowel Project Protocol B-27
    • Bear HD, Anderson S, Smith RE, Geyer Jr CE, Mamounas EP, Fisher B, et al. Sequential preoperative or postoperative docetaxel added to preoperative doxorubicin plus cyclophosphamide for operable breast cancer: National Surgical Adjuvant Breast and Bowel Project Protocol B-27. J Clin Oncol. 2006;24(13):2019-27.
    • (2006) J Clin Oncol , vol.24 , Issue.13 , pp. 2019-2027
    • Bear, H.D.1    Anderson, S.2    Smith, R.E.3    Geyer, C.E.4    Mamounas, E.P.5    Fisher, B.6    Brown, A.M.7    Robidoux, A.8    Margolese, R.9    Kahlenberg, M.S.10
  • 3
    • 66249091930 scopus 로고    scopus 로고
    • The HER-2 receptor and breast cancer: ten years of targeted anti-HER-2 therapy and personalized medicine
    • Ross JS, Slodkowska EA, Symmans WF, Pusztai L, Ravdin PM, Hortobagyi GN. The HER-2 receptor and breast cancer: ten years of targeted anti-HER-2 therapy and personalized medicine. Oncologist. 2009;14(4):320-68.
    • (2009) Oncologist , vol.14 , Issue.4 , pp. 320-368
    • Ross, J.S.1    Slodkowska, E.A.2    Symmans, W.F.3    Pusztai, L.4    Ravdin, P.M.5    Hortobagyi, G.N.6
  • 4
    • 18744395754 scopus 로고    scopus 로고
    • Preoperative therapy with trastuzumab and paclitaxel followed by sequential adjuvant doxorubicin/cyclophosphamide for HER2 overexpressing stage II or III breast cancer: a pilot study
    • Burstein HJ, Harris LN, Gelman R, Lester SC, Nunes RA, Kaelin CM, et al. Preoperative therapy with trastuzumab and paclitaxel followed by sequential adjuvant doxorubicin/cyclophosphamide for HER2 overexpressing stage II or III breast cancer: a pilot study. J Clin Oncol. 2003;21(1):46-53.
    • (2003) J Clin Oncol , vol.21 , Issue.1 , pp. 46-53
    • Burstein, H.J.1    Harris, L.N.2    Gelman, R.3    Lester, S.C.4    Nunes, R.A.5    Kaelin, C.M.6    Parker, L.M.7    Ellisen, L.W.8    Kuter, I.9    Gadd, M.A.10
  • 5
    • 84855297353 scopus 로고    scopus 로고
    • Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial
    • Gianni L, Pienkowski T, Im YH, Roman L, Tseng LM, Liu MC, et al. Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial. Lancet Oncol. 2012;13:25-32.
    • (2012) Lancet Oncol , vol.13 , pp. 25-32
    • Gianni, L.1    Pienkowski, T.2    Im, Y.H.3    Roman, L.4    Tseng, L.M.5    Liu, M.C.6    Lluch, A.7    Staroslawska, E.8    Rodriguez, J.H.9    Im, S.A.10
  • 7
    • 34247100686 scopus 로고    scopus 로고
    • Phase II study of neoadjuvant docetaxel, vinorelbine, and trastuzumab followed by surgery and adjuvant doxorubicin plus cyclophosphamide in women with human epidermal growth factor receptor 2-overexpressing locally advanced breast cancer
    • Limentani SA, Brufsky AM, Erban JK, Jahanzeb M, Lewis D. Phase II study of neoadjuvant docetaxel, vinorelbine, and trastuzumab followed by surgery and adjuvant doxorubicin plus cyclophosphamide in women with human epidermal growth factor receptor 2-overexpressing locally advanced breast cancer. J Clin Oncol. 2007;25(10):1232-8.
    • (2007) J Clin Oncol , vol.25 , Issue.10 , pp. 1232-1238
    • Limentani, S.A.1    Brufsky, A.M.2    Erban, J.K.3    Jahanzeb, M.4    Lewis, D.5
  • 8
    • 20544460650 scopus 로고    scopus 로고
    • Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancer
    • Buzdar AU, Ibrahim NK, Francis D, Booser DJ, Thomas ES, Theriault RL, et al. Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancer. J Clin Oncol. 2005;23:3676-85.
    • (2005) J Clin Oncol , vol.23 , pp. 3676-3685
    • Buzdar, A.U.1    Ibrahim, N.K.2    Francis, D.3    Booser, D.J.4    Thomas, E.S.5    Theriault, R.L.6    Pusztai, L.7    Green, M.C.8    Arun, B.K.9    Giordano, S.H.10
  • 9
    • 21644438384 scopus 로고    scopus 로고
    • The diverse signaling network of EGFR, HER2, HER3 and HER4 tyrosine kinase receptors and the consequences for therapeutic approaches
    • Zaczek A, Brandt B, Bielawski KP. The diverse signaling network of EGFR, HER2, HER3 and HER4 tyrosine kinase receptors and the consequences for therapeutic approaches. Histol Histopathol. 2005;20(3):1005-15.
    • (2005) Histol Histopathol , vol.20 , Issue.3 , pp. 1005-1015
    • Zaczek, A.1    Brandt, B.2    Bielawski, K.P.3
  • 14
    • 84883821225 scopus 로고    scopus 로고
    • Antibody therapeutics in cancer
    • Sliwkowski MX, Mellman I. Antibody therapeutics in cancer. Science. 2013;341(6151):1192-8.
    • (2013) Science , vol.341 , Issue.6151 , pp. 1192-1198
    • Sliwkowski, M.X.1    Mellman, I.2
  • 15
    • 0028200221 scopus 로고
    • Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells
    • Pietras RJ, Fendly BM, Chazin VR, Pegram MD, Howell SB, Slamon DJ. Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells. Oncogene. 1994;9(7):1829-38.
    • (1994) Oncogene , vol.9 , Issue.7 , pp. 1829-1838
    • Pietras, R.J.1    Fendly, B.M.2    Chazin, V.R.3    Pegram, M.D.4    Howell, S.B.5    Slamon, D.J.6
  • 20
    • 33846297680 scopus 로고    scopus 로고
    • Neoadjuvant therapy with paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide chemotherapy and concurrent trastuzumab in human epidermal growth factor receptor 2-positive operable breast cancer: an update of the initial randomized study population and data of additional patients treated with the same regimen
    • Buzdar AU, Valero V, Ibrahim NK, Francis D, Broglio KR, Theriault RL, et al. Neoadjuvant therapy with paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide chemotherapy and concurrent trastuzumab in human epidermal growth factor receptor 2-positive operable breast cancer: an update of the initial randomized study population and data of additional patients treated with the same regimen. Clin Cancer Res. 2007;13:228-33.
    • (2007) Clin Cancer Res , vol.13 , pp. 228-233
    • Buzdar, A.U.1    Valero, V.2    Ibrahim, N.K.3    Francis, D.4    Broglio, K.R.5    Theriault, R.L.6    Pusztai, L.7    Green, M.C.8    Singletary, S.E.9    Hunt, K.K.10
  • 21
    • 79957601951 scopus 로고    scopus 로고
    • Pathologic complete response after neoadjuvant chemotherapy plus trastuzumab predicts favorable survival in human epidermal growth factor receptor 2-overexpressing breast cancer: results from the TECHNO trial of the AGO and GBG study groups
    • Untch M, Fasching PA, Konecny GE, Hasmuller S, Lebeau A, Kreienberg R, et al. Pathologic complete response after neoadjuvant chemotherapy plus trastuzumab predicts favorable survival in human epidermal growth factor receptor 2-overexpressing breast cancer: results from the TECHNO trial of the AGO and GBG study groups. J Clin Oncol. 2011;29(25):3351-7.
    • (2011) J Clin Oncol , vol.29 , Issue.25 , pp. 3351-3357
    • Untch, M.1    Fasching, P.A.2    Konecny, G.E.3    Hasmuller, S.4    Lebeau, A.5    Kreienberg, R.6    Camara, O.7    Muller, V.8    Bois, A.9    Kuhn, T.10
  • 23
    • 0028176483 scopus 로고
    • Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
    • Polyak K, Lee MH, Erdjument-Bromage H, Koff A, Roberts JM, Tempst P, et al. Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell. 1994;78(1):59-66.
    • (1994) Cell , vol.78 , Issue.1 , pp. 59-66
    • Polyak, K.1    Lee, M.H.2    Erdjument-Bromage, H.3    Koff, A.4    Roberts, J.M.5    Tempst, P.6    Massague, J.7
  • 24
    • 0028363519 scopus 로고
    • p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21
    • Toyoshima H, Hunter T. p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell. 1994;78(1):67-74.
    • (1994) Cell , vol.78 , Issue.1 , pp. 67-74
    • Toyoshima, H.1    Hunter, T.2
  • 25
    • 15644368112 scopus 로고    scopus 로고
    • Activation of cyclin-dependent kinase 2 (Cdk2) in growth-stimulated rat astrocytes. Geranylgeranylated Rho small GTPase(s) are essential for the induction of cyclin E gene expression
    • Tanaka T, Tatsuno I, Noguchi Y, Uchida D, Oeda T, Narumiya S, et al. Activation of cyclin-dependent kinase 2 (Cdk2) in growth-stimulated rat astrocytes. Geranylgeranylated Rho small GTPase(s) are essential for the induction of cyclin E gene expression. J Biol Chem. 1998;273(41):26772-8.
    • (1998) J Biol Chem , vol.273 , Issue.41 , pp. 26772-26778
    • Tanaka, T.1    Tatsuno, I.2    Noguchi, Y.3    Uchida, D.4    Oeda, T.5    Narumiya, S.6    Yasuda, T.7    Higashi, H.8    Kitagawa, M.9    Nakayama, K.10
  • 27
    • 2542526069 scopus 로고    scopus 로고
    • P27 (kip1) down-regulation is associated with trastuzumab resistance in breast cancer cells
    • Nahta R, Takahashi T, Ueno NT, Hung MC, Esteva FJ. P27 (kip1) down-regulation is associated with trastuzumab resistance in breast cancer cells. Cancer Res. 2004;64:3981-6.
    • (2004) Cancer Res , vol.64 , pp. 3981-3986
    • Nahta, R.1    Takahashi, T.2    Ueno, N.T.3    Hung, M.C.4    Esteva, F.J.5
  • 28
    • 78650208364 scopus 로고    scopus 로고
    • Mechanisms of resistance to anti-human epidermal growth factor receptor 2 agents in breast cancer
    • Mukohara T. Mechanisms of resistance to anti-human epidermal growth factor receptor 2 agents in breast cancer. Cancer Sci. 2011;102:1-8.
    • (2011) Cancer Sci , vol.102 , pp. 1-8
    • Mukohara, T.1
  • 29
    • 0036799377 scopus 로고    scopus 로고
    • PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization
    • Shin I, Yakes FM, Rojo F, Shin NY, Bakin AV, Baselga J, et al. PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization. Nat Med. 2002;8(10):1145-52.
    • (2002) Nat Med , vol.8 , Issue.10 , pp. 1145-1152
    • Shin, I.1    Yakes, F.M.2    Rojo, F.3    Shin, N.Y.4    Bakin, A.V.5    Baselga, J.6    Arteaga, C.L.7
  • 30
    • 0032444464 scopus 로고    scopus 로고
    • Prognostic implications of expression of the cell cycle inhibitor protein p27Kip1
    • Cariou S, Catzavelos C, Slingerland JM. Prognostic implications of expression of the cell cycle inhibitor protein p27Kip1. Breast Cancer Res Treat. 1998;52(1-3):29-41.
    • (1998) Breast Cancer Res Treat , vol.52 , Issue.1-3 , pp. 29-41
    • Cariou, S.1    Catzavelos, C.2    Slingerland, J.M.3
  • 34
    • 78249249610 scopus 로고    scopus 로고
    • p27Kip1 is a predictive factor for tamoxifen treatment response but not a prognostic marker in premenopausal breast cancer patients
    • Stendahl M, Nilsson S, Wigerup C, Jirstrom K, Jonsson PE, Stal O, et al. p27Kip1 is a predictive factor for tamoxifen treatment response but not a prognostic marker in premenopausal breast cancer patients. Int J Cancer. 2010;127:2851-8.
    • (2010) Int J Cancer , vol.127 , pp. 2851-2858
    • Stendahl, M.1    Nilsson, S.2    Wigerup, C.3    Jirstrom, K.4    Jonsson, P.E.5    Stal, O.6    Landberg, G.7
  • 35
    • 84905920752 scopus 로고    scopus 로고
    • First results from the phase III ALTTO trial (BIG 2-06; NCCTG [Alliance] N063D) comparing one year of anti-HER2 therapy with lapatinib alone (L), trastuzumab alone (T), their sequence (T → L), or their combination (T + L) in the adjuvant treatment of HER2-positive early breast cancer (EBC)
    • Piccart-Gebhart MJ, Holmes AP, Baselga J, Azambuja ED, Dueck AC, Viale G, et al. First results from the phase III ALTTO trial (BIG 2-06; NCCTG [Alliance] N063D) comparing one year of anti-HER2 therapy with lapatinib alone (L), trastuzumab alone (T), their sequence (T → L), or their combination (T + L) in the adjuvant treatment of HER2-positive early breast cancer (EBC). J Clin Oncol. 2014;32:5s.
    • (2014) J Clin Oncol , vol.32 , pp. 5s
    • Piccart-Gebhart, M.J.1    Holmes, A.P.2    Baselga, J.3    Azambuja, E.D.4    Dueck, A.C.5    Viale, G.6    Zujewski, J.A.7    Goldhirsch, A.8    Santillana, S.9    Pritchard, K.I.10
  • 36
    • 84904188903 scopus 로고    scopus 로고
    • Pathological complete response and long-term clinical benefit in breast cancer: the CTNeoBC pooled analysis
    • sFeb 13 [Epub ahead of print], 10.1016
    • Cortazar P, Zhang L, Untch M, Mehta K, Costantino JP, Wolmark N, et al. Pathological complete response and long-term clinical benefit in breast cancer: the CTNeoBC pooled analysis. Lancet 2014, Feb 13 [Epub ahead of print] doi: 10.1016.
    • (2014) Lancet
    • Cortazar, P.1    Zhang, L.2    Untch, M.3    Mehta, K.4    Costantino, J.P.5    Wolmark, N.6
  • 38
    • 77949357106 scopus 로고    scopus 로고
    • Immunohistochemical surrogate markers of breast cancer molecular classes predicts response to neoadjuvant chemotherapy: a single institutional experience with 359 cases
    • Bhargava R, Beriwal S, Dabbs DJ, Ozbek U, Soran A, Johnson RR, et al. Immunohistochemical surrogate markers of breast cancer molecular classes predicts response to neoadjuvant chemotherapy: a single institutional experience with 359 cases. Cancer. 2010;116(6):1431-9.
    • (2010) Cancer , vol.116 , Issue.6 , pp. 1431-1439
    • Bhargava, R.1    Beriwal, S.2    Dabbs, D.J.3    Ozbek, U.4    Soran, A.5    Johnson, R.R.6    Brufsky, A.M.7    Lembersky, B.C.8    Ahrendt, G.M.9
  • 39
    • 84876431891 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy in breast cancer - insights from the German experience
    • von Minckwitz G. Neoadjuvant chemotherapy in breast cancer - insights from the German experience. Breast Cancer. 2012;19:282-8.
    • (2012) Breast Cancer , vol.19 , pp. 282-288
    • Minckwitz, G.1


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