Chorismatase Mechanisms Reveal Fundamentally Different Types of Reaction in a Single Conserved Protein Fold

Journal of the American Chemical Society

Volumn 137, Issue 34, 2015, Pages 11032-11037

  Hubrich, Florian ^a   Juneja, Puneet ^b,c   Müller, Michael ^a   Diederichs, Kay ^b   Welte, Wolfram ^b   Andexer, Jennifer N ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF KONSTANZ   (Germany)

^c Department of Structural Biochemistry   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ENZYMES; PROTEIN FOLDING; PROTEINS;

ACTIVE SITE RESIDUES; AMINO ACID RESIDUES; BENZOATE DERIVATIVE; BIOSYNTHETIC PATHWAY; CHEMICAL EQUATIONS; CONSERVED PROTEINS; MULTIPLE SEQUENCE ALIGNMENTS; REACTION MECHANISM;

REACTION INTERMEDIATES;

AMINO ACID; BENZOIC ACID DERIVATIVE; CHORISMATASE; CHORISMIC ACID; HYDROXYBENZOIC ACID; OXIDE; UNCLASSIFIED DRUG; CHORISMATE SYNTHASE; LYASE;

ADDITION REACTION; ARTICLE; CATALYST; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME MECHANISM; HYDROLYSIS; NONHUMAN; PROTEIN FOLDING; PROTEIN MOTIF; REACTION ANALYSIS; SEQUENCE ALIGNMENT; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM;

MODELS, MOLECULAR; MOLECULAR STRUCTURE; PHOSPHORUS-OXYGEN LYASES; PROTEIN FOLDING;

EID: 84940868486     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.5b05559     Document Type: Article

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