Synergistic Effects of SDF-1α and BMP-2 Delivery from Proteolytically Degradable Hyaluronic Acid Hydrogels for Bone Repair

Macromolecular Bioscience

Volumn 15, Issue 9, 2015, Pages 1218-1223

  Holloway, Julianne L ^a   Ma, Henry ^a   Rai, Reena ^a   Hankenson, Kurt D ^b   Burdick, Jason A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

bone morphogenetic protein; bone tissue engineering; drug delivery; hyaluronic acid; hydrogel; stromal cell derived factor 1

Indexed keywords

BIOMOLECULES; BONE; CELL ENGINEERING; DRUG DELIVERY; HYALURONIC ACID; ORGANIC ACIDS; PROTEINS; TISSUE ENGINEERING;

ADVERSE SIDE EFFECTS; BIOMOLECULE DELIVERIES; BONE MORPHOGENETIC PROTEIN-2; BONE MORPHOGENETIC PROTEINS; BONE TISSUE ENGINEERING; HYALURONIC ACID HYDROGELS; PROTEOLYTICALLY DEGRADABLE HYDROGELS; STROMAL CELLS;

HYDROGELS;

BONE MORPHOGENETIC PROTEIN 2; COLLAGENASE; HYALURONIC ACID; STROMAL CELL DERIVED FACTOR 1ALPHA; BMP2 PROTEIN, HUMAN; CXCL12 PROTEIN, HUMAN; HYDROGEL; STROMAL CELL DERIVED FACTOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE MASS; BONE REGENERATION; BONE REMODELING; CALVARIA; CELL INVASION; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG POTENTIATION; HYDROGEL; IN VIVO STUDY; MALE; NONHUMAN; OSSIFICATION; PROTEIN DEGRADATION; RAT; ANIMAL; BIODEGRADABLE IMPLANT; CHEMISTRY; DRUG EFFECTS; SPRAGUE DAWLEY RAT;

ABSORBABLE IMPLANTS; ANIMALS; BONE MORPHOGENETIC PROTEIN 2; BONE REGENERATION; CHEMOKINE CXCL12; DRUG SYNERGISM; HYALURONIC ACID; HYDROGELS; MALE; OSTEOGENESIS; PROTEOLYSIS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84940791794     PISSN: 16165187     EISSN: 16165195     Source Type: Journal    
DOI: 10.1002/mabi.201500178     Document Type: Article

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