Innate Immunity and the Inter-exposure Interval Determine the Dynamics of Secondary Influenza Virus Infection and Explain Observed Viral Hierarchies

PLoS Computational Biology

Volumn 11, Issue 8, 2015, Pages

  Cao, Pengxing ^a   Yan, Ada W C ^a   Heffernan, Jane M ^a,b   Petrie, Stephen ^a   Moss, Robert G ^a   Carolan, Louise A ^c   Guarnaccia, Teagan A ^c   Kelso, Anne ^c   Barr, Ian G ^c   McVernon, Jodie ^a,d   Laurie, Karen L ^c   McCaw, James M ^a,d,e  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b YORK UNIVERSITY   (Canada)

^c WHO COLLABORATING CENTRE FOR REFERENCE AND RESEARCH ON INFLUENZA   (Australia)

^d ROYAL CHILDREN'S HOSPITAL   (Australia)

^e UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNE SYSTEM; RESPIRATORY SYSTEM;

ANTIVIRALS; IMMUNE RESPONSE; INFECTIOUS DISEASE; INFLUENZA VIRUS; INNATE IMMUNE RESPONSE; INNATE IMMUNITY; MODELLING STUDIES; TEMPORARY IMMUNITY; VIRUS INFECTION; VIRUS STRAINS;

VIRUSES;

ARTICLE; CONTROLLED STUDY; IMMUNE RESPONSE; IMMUNOSTIMULATION; INFECTION CONTROL; INFLUENZA; INNATE IMMUNITY; MATHEMATICAL MODEL; PRIMARY INFECTION; REINFECTION; SECONDARY INFECTION; VIRUS REPLICATION; ANIMAL; BIOLOGICAL MODEL; BIOLOGY; DISEASE MODEL; FERRET; HOST PATHOGEN INTERACTION; HUMAN; IMMUNOLOGY; ORTHOMYXOVIRIDAE; ORTHOMYXOVIRUS INFECTION; PATHOGENICITY; VIROLOGY; VIRUS LOAD;

ANIMALS; COMPUTATIONAL BIOLOGY; DISEASE MODELS, ANIMAL; FERRETS; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, INNATE; INFLUENZA, HUMAN; MODELS, IMMUNOLOGICAL; ORTHOMYXOVIRIDAE; ORTHOMYXOVIRIDAE INFECTIONS; VIRAL LOAD;

EID: 84940774944     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1004334     Document Type: Article

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