Curcumin Targeted, Polymalic Acid-Based MRI Contrast Agent for the Detection of Aβ Plaques in Alzheimer's Disease

Macromolecular Bioscience

Volumn 15, Issue 9, 2015, Pages 1212-1217

  Patil, Rameshwar ^a   Gangalum, Pallavi R ^a   Wagner, Shawn ^a   Portilla Arias, Jose ^a   Ding, Hui ^a   Rekechenetskiy, Arthur ^a   Konda, Bindu ^a   Inoue, Satoshi ^a   Black, Keith L ^a   Ljubimova, Julia Y ^a   Holler, Eggehard ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

Alzheimer disease; curcumin; MRI; nanoimaging agent; polymalic acid

Indexed keywords

DIAGNOSIS; GADOLINIUM; NEURODEGENERATIVE DISEASES;

ALZHEIMER DISEASE; ALZHEIMER'S DISEASE; CURCUMIN; MRI CONTRAST AGENTS; NANO-IMAGING; NON-INVASIVE DIAGNOSIS; PATIENT SURVIVALS; POLYMALIC ACID;

MAGNETIC RESONANCE IMAGING;

AMYLOID BETA PROTEIN; CURCUMIN; GADOTERIC ACID; MALIC ACID DERIVATIVE; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; CONTRAST MEDIUM; GADOLINIUM 1,4,7,10-TETRAAZACYCLODODECANE-N,N',N'',N'''-TETRAACETATE; HETEROCYCLIC COMPOUND; ORGANOMETALLIC COMPOUND; POLY(MALIC ACID); POLYMER;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; COVALENT BOND; DRUG PROTEIN BINDING; EX VIVO STUDY; HUMAN; HUMAN TISSUE; MOUSE; NANOIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PROTEIN ANALYSIS; ANALOGS AND DERIVATIVES; ANIMAL; BRAIN; CHEMISTRY; PATHOLOGY; PLAQUE, AMYLOID;

ALZHEIMER DISEASE; ANIMALS; BRAIN; CONTRAST MEDIA; CURCUMIN; HETEROCYCLIC COMPOUNDS; HUMANS; MAGNETIC RESONANCE IMAGING; MALATES; MICE; ORGANOMETALLIC COMPOUNDS; PLAQUE, AMYLOID; POLYMERS;

EID: 84940773292     PISSN: 16165187     EISSN: 16165195     Source Type: Journal    
DOI: 10.1002/mabi.201500062     Document Type: Article

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