-
1
-
-
84856431125
-
Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities
-
Boyden LM, Choi M, Choate KA, Nelson-Williams CJ, Farhi A, Toka HR, Tikhonova IR, Bjornson R, Mane SM, Colussi G, Lebel M, Gordon RD, Semmekrot BA, Poujol A, Vlimki MJ, De Ferrari ME, Sanjad SA, Gutkin M, Karet FE, Tucci JR, Stockigt JR, Keppler-NoreuilKM, Porter CC, Anand SK, WhitefordML, Davis ID,Dewar SB, Bettinelli A, Fadrowski JJ, Belsha CW, Hunley TE, Nelson RD, Trachtman H, Cole TR, Pinsk M, Bockenhauer D, ShenoyM, Vaidyanathan P, Foreman JW,RasoulpourM,ThameemF, Al-ShahrouriHZ, Radhakrishnan J,GharaviAG, Goilav B, Lifton RP:Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities. Nature 482: 98-102, 2012
-
(2012)
Nature
, vol.482
, pp. 98-102
-
-
Boyden, L.M.1
Choi, M.2
Choate, K.A.3
Nelson-Williams, C.J.4
Farhi, A.5
Toka, H.R.6
Tikhonova, I.R.7
Bjornson, R.8
Mane, S.M.9
Colussi, G.10
Lebel, M.11
Gordon, R.D.12
Semmekrot, B.A.13
Poujol, A.14
Välimäki, M.J.15
De Ferrari, M.E.16
Sanjad, S.A.17
Gutkin, M.18
Karet, F.E.19
Tucci, J.R.20
Stockigt, J.R.21
Keppler-Noreuil, K.M.22
Porter, C.C.23
Anand, S.K.24
Whiteford, M.L.25
Davis, I.D.26
Dewar, S.B.27
Bettinelli, A.28
Fadrowski, J.J.29
Belsha, C.W.30
Hunley, T.E.31
Nelson, R.D.32
Trachtman, H.33
Cole, T.R.34
Pinsk, M.35
Bockenhauer, D.36
Shenoy, M.37
Vaidyanathan, P.38
Foreman, J.W.39
Rasoulpour, M.40
Thameem, F.41
Al-Shahrouri, H.Z.42
Radhakrishnan, J.43
Gharavi, A.G.44
Goilav, B.45
Lifton, R.P.46
more..
-
2
-
-
17944373014
-
Human hypertension caused by mutations in WNK kinases
-
Wilson FH, Disse-Nicodme S, Choate KA, Ishikawa K,Nelson-Williams C, Desitter I, Gunel M, Milford DV, Lipkin GW, Achard JM, Feely MP, Dussol B, Berland Y, Unwin RJ, Mayan H, Simon DB, Farfel Z, Jeunemaitre X, Lifton RP: Human hypertension caused by mutations in WNK kinases. Science 293: 1107-1112, 2001
-
(2001)
Science
, vol.293
, pp. 1107-1112
-
-
Wilson, F.H.1
Disse-Nicodme, S.2
Choate, K.A.3
Ishikawa, K.4
Nelson-Williams, C.5
Desitter, I.6
Gunel, M.7
Milford, D.V.8
Lipkin, G.W.9
Achard, J.M.10
Feely, M.P.11
Dussol, B.12
Berland, Y.13
Unwin, R.J.14
Mayan, H.15
Simon, D.B.16
Farfel, Z.17
Jeunemaitre, X.18
Lifton, R.P.19
-
3
-
-
84859425383
-
KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron
-
Louis-Dit-Picard H, Barc J, Trujillano D, Miserey-Lenkei S, Bouatia-Naji N, Pylypenko O, Beaurain G, Bonnefond A, Sand O, Simian C, Vidal-Petiot E, Soukaseum C, Mandet C, Broux F, Chabre O, Delahousse M, Esnault V, Fiquet B, Houillier P, Bagnis CI, Koenig J, KonradM, Landais P, Mourani C, Niaudet P, Probst V, Thauvin C, Unwin RJ, Soroka SD, Ehret G, Ossowski S, Caulfield M; International Consortium for Blood Pressure (ICBP)Bruneval P, Estivill X, Froguel P, Hadchouel J, Schott JJ, Jeunemaitre X: KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron. Nat Genet 44: 456-460, 2012
-
(2012)
Nat Genet
, vol.44
, pp. 456-460
-
-
Louis-Dit-Picard, H.1
Barc, J.2
Trujillano, D.3
Miserey-Lenkei, S.4
Bouatia-Naji, N.5
Pylypenko, O.6
Beaurain, G.7
Bonnefond, A.8
Sand, O.9
Simian, C.10
Vidal-Petiot, E.11
Soukaseum, C.12
Mandet, C.13
Broux, F.14
Chabre, O.15
Delahousse, M.16
Esnault, V.17
Fiquet, B.18
Houillier, P.19
Bagnis, C.I.20
Koenig, J.21
Konrad, M.22
Landais, P.23
Mourani, C.24
Niaudet, P.25
Probst, V.26
Thauvin, C.27
Unwin, R.J.28
Soroka, S.D.29
Ehret, G.30
Ossowski, S.31
Caulfield, M.32
Bruneval, P.33
Estivill, X.34
Froguel, P.35
Hadchouel, J.36
Schott, J.J.37
Jeunemaitre, X.38
more..
-
4
-
-
84875813488
-
Impaired KLHL3-mediated ubiquitination of WNK4 causes human hypertension
-
Wakabayashi M, Mori T, Isobe K, Sohara E, Susa K, Araki Y, Chiga M, Kikuchi E, Nomura N, Mori Y, Matsuo H, Murata T, Nomura S, Asano T, Kawaguchi H, Nonoyama S, Rai T, Sasaki S, Uchida S: Impaired KLHL3-mediated ubiquitination of WNK4 causes human hypertension. Cell Rep 3: 858-868, 2013
-
(2013)
Cell Rep
, vol.3
, pp. 858-868
-
-
Wakabayashi, M.1
Mori, T.2
Isobe, K.3
Sohara, E.4
Susa, K.5
Araki, Y.6
Chiga, M.7
Kikuchi, E.8
Nomura, N.9
Mori, Y.10
Matsuo, H.11
Murata, T.12
Nomura, S.13
Asano, T.14
Kawaguchi, H.15
Nonoyama, S.16
Rai, T.17
Sasaki, S.18
Uchida, S.19
-
5
-
-
84875158737
-
The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: Disease-causing mutations in KLHL3 and WNK4 disrupt interaction
-
Ohta A, Schumacher FR, Mehellou Y, Johnson C, Knebel A, Macartney TJ, Wood NT, Alessi DR, Kurz T: The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: Disease-causing mutations in KLHL3 and WNK4 disrupt interaction. Biochem J 451: 111-122, 2013
-
(2013)
Biochem J
, vol.451
, pp. 111-122
-
-
Ohta, A.1
Schumacher, F.R.2
Mehellou, Y.3
Johnson, C.4
Knebel, A.5
Macartney, T.J.6
Wood, N.T.7
Alessi, D.R.8
Kurz, T.9
-
6
-
-
84880944866
-
KLHL2 interactswith and ubiquitinatesWNK kinases
-
Takahashi D, Mori T,Wakabayashi M, Mori Y, Susa K, Zeniya M, Sohara E, Rai T, Sasaki S, Uchida S: KLHL2 interactswith and ubiquitinatesWNK kinases. Biochem Biophys Res Commun 437: 457-462, 2013
-
(2013)
Biochem Biophys Res Commun
, vol.437
, pp. 457-462
-
-
Takahashi, D.1
Mori, T.2
Wakabayashi, M.3
Mori, Y.4
Susa, K.5
Zeniya, M.6
Sohara, E.7
Rai, T.8
Sasaki, S.9
Uchida, S.10
-
7
-
-
56549094967
-
Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone
-
ChigaM, Rai T, Yang SS,Ohta A, Takizawa T, Sasaki S, Uchida S: Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone. Kidney Int 74: 1403-1409, 2008
-
(2008)
Kidney Int
, vol.74
, pp. 1403-1409
-
-
Chiga, M.1
Rai, T.2
Yang, S.S.3
Ohta, A.4
Takizawa, T.5
Sasaki, S.6
Uchida, S.7
-
8
-
-
77949654325
-
Effect of angiotensin II on the WNK-OSR1/SPAK-NCC phosphorylation cascade in cultured mpkDCT cells and in vivo mouse kidney
-
Talati G, Ohta A, Rai T, Sohara E, Naito S, Vandewalle A, Sasaki S, Uchida S: Effect of angiotensin II on the WNK-OSR1/SPAK-NCC phosphorylation cascade in cultured mpkDCT cells and in vivo mouse kidney. Biochem Biophys Res Commun 393: 844-848, 2010
-
(2010)
Biochem Biophys Res Commun
, vol.393
, pp. 844-848
-
-
Talati, G.1
Ohta, A.2
Rai, T.3
Sohara, E.4
Naito, S.5
Vandewalle, A.6
Sasaki, S.7
Uchida, S.8
-
9
-
-
84900834795
-
WNK4 is the majorWNK positively regulating NCC in the mouse kidney
-
Takahashi D, Mori T, Nomura N, Khan MZ, Araki Y, Zeniya M, Sohara E, Rai T, Sasaki S, Uchida S:WNK4 is the majorWNK positively regulating NCC in the mouse kidney. Biosci Rep 34: e00107, 2014
-
(2014)
Biosci Rep
, vol.34
, pp. e00107
-
-
Takahashi, D.1
Mori, T.2
Nomura, N.3
Khan, M.Z.4
Araki, Y.5
Zeniya, M.6
Sohara, E.7
Rai, T.8
Sasaki, S.9
Uchida, S.10
-
10
-
-
84866543932
-
Phosphatidylinositol 3-kinase/Akt signaling pathway activates the WNK-OSR1/SPAK-NCC phosphorylation cascade in hyperinsulinemic db/db mice
-
Nishida H, Sohara E, Nomura N, Chiga M, Alessi DR, Rai T, Sasaki S, Uchida S: Phosphatidylinositol 3-kinase/Akt signaling pathway activates the WNK-OSR1/SPAK-NCC phosphorylation cascade in hyperinsulinemic db/db mice. Hypertension 60: 981-990, 2012
-
(2012)
Hypertension
, vol.60
, pp. 981-990
-
-
Nishida, H.1
Sohara, E.2
Nomura, N.3
Chiga, M.4
Alessi, D.R.5
Rai, T.6
Sasaki, S.7
Uchida, S.8
-
11
-
-
84874621317
-
SPAK differentially mediates vasopressin effects on sodiumcotransporters
-
Saritas T, Borschewski A, McCormick JA, Paliege A, Dathe C, Uchida S, Terker A, Himmerkus N, Bleich M, Demaretz S, Laghmani K, Delpire E, Ellison DH, Bachmann S, Mutig K: SPAK differentially mediates vasopressin effects on sodiumcotransporters. JAmSocNephrol 24: 407-418, 2013
-
(2013)
JAmSocNephrol
, vol.24
, pp. 407-418
-
-
Saritas, T.1
Borschewski, A.2
McCormick, J.A.3
Paliege, A.4
Dathe, C.5
Uchida, S.6
Terker, A.7
Himmerkus, N.8
Bleich, M.9
Demaretz, S.10
Laghmani, K.11
Delpire, E.12
Ellison, D.H.13
Bachmann, S.14
Mutig, K.15
-
12
-
-
84886420604
-
Dietary salt intake regulates WNK3-SPAK-NKCC1 phosphorylation cascade in mouse aorta through angiotensin II
-
Zeniya M, Sohara E, Kita S, Iwamoto T, Susa K, Mori T, Oi K, Chiga M, Takahashi D, Yang SS, Lin SH, Rai T, Sasaki S, Uchida S: Dietary salt intake regulates WNK3-SPAK-NKCC1 phosphorylation cascade in mouse aorta through angiotensin II. Hypertension 62: 872-878, 2013
-
(2013)
Hypertension
, vol.62
, pp. 872-878
-
-
Zeniya, M.1
Sohara, E.2
Kita, S.3
Iwamoto, T.4
Susa, K.5
Mori, T.6
Oi, K.7
Chiga, M.8
Takahashi, D.9
Yang, S.S.10
Lin, S.H.11
Rai, T.12
Sasaki, S.13
Uchida, S.14
-
13
-
-
84862512476
-
NKCC1 and hypertension: Role in the regulation of vascular smooth muscle contractions and myogenic tone
-
Orlov SN, Koltsova SV, Tremblay J, Baskakov MB,Hamet P:NKCC1 and hypertension: Role in the regulation of vascular smooth muscle contractions and myogenic tone. Ann Med 44[Suppl 1]: S111-S118, 2012
-
(2012)
Ann Med
, vol.44
, pp. S111-S118
-
-
Orlov, S.N.1
Koltsova, S.V.2
Tremblay, J.3
Baskakov, M.B.4
Hamet, P.5
-
14
-
-
0042847432
-
PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1)
-
Dowd BF, Forbush B: PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1). J Biol Chem 278: 27347-27353, 2003
-
(2003)
J Biol Chem
, vol.278
, pp. 27347-27353
-
-
Dowd, B.F.1
Forbush, B.2
-
15
-
-
46149116565
-
Regulation of NKCC2 by a chloridesensing mechanism involving the WNK3 and SPAK kinases
-
Ponce-Coria J, San-Cristobal P, Kahle KT, Vazquez N, Pacheco-Alvarez D, de LosHeros P, Juárez P,Muñoz E,MichelG, BobadillaNA,Gimenez I, Lifton RP, Hebert SC, Gamba G: Regulation of NKCC2 by a chloridesensing mechanism involving the WNK3 and SPAK kinases. Proc Natl Acad Sci U S A 105: 8458-8463, 2008
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 8458-8463
-
-
Ponce-Coria, J.1
San-Cristobal, P.2
Kahle, K.T.3
Vazquez, N.4
Pacheco-Alvarez, D.5
de LosHeros, P.6
Juárez, P.7
Muñoz, E.8
Michel, G.9
Bobadilla, N.A.10
Gimenez, I.11
Lifton, R.P.12
Hebert, S.C.13
Gamba, G.14
-
16
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
Itoh K,Wakabayashi N, Katoh Y, Ishii T, Igarashi K, Engel JD, Yamamoto M: Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev 13: 76-86, 1999
-
(1999)
Genes Dev
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
Yamamoto, M.7
-
17
-
-
77649265091
-
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
-
KomatsuM, Kurokawa H,Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou YS, Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S, Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M: The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1. Nat Cell Biol 12: 213-223, 2010
-
(2010)
Nat Cell Biol
, vol.12
, pp. 213-223
-
-
Komatsu, M.1
Kurokawa, H.2
Waguri, S.3
Taguchi, K.4
Kobayashi, A.5
Ichimura, Y.6
Sou, Y.S.7
Ueno, I.8
Sakamoto, A.9
Tong, K.I.10
Kim, M.11
Nishito, Y.12
Iemura, S.13
Natsume, T.14
Ueno, T.15
Kominami, E.16
Motohashi, H.17
Tanaka, K.18
Yamamoto, M.19
-
18
-
-
77955352128
-
Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy
-
FanW, Tang Z, Chen D, Moughon D, Ding X, Chen S, Zhu M, Zhong Q: Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy. Autophagy 6: 614-621, 2010
-
(2010)
Autophagy
, vol.6
, pp. 614-621
-
-
Fan, W.1
Tang, Z.2
Chen, D.3
Moughon, D.4
Ding, X.5
Chen, S.6
Zhu, M.7
Zhong, Q.8
-
19
-
-
84877340391
-
Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4
-
Shibata S, Zhang J, Puthumana J, Stone KL, Lifton RP: Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4. Proc Natl Acad Sci U S A 110: 7838-7843, 2013
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 7838-7843
-
-
Shibata, S.1
Zhang, J.2
Puthumana, J.3
Stone, K.L.4
Lifton, R.P.5
-
20
-
-
84878774970
-
Disease-causingmutations in KLHL3 impair its effect on WNK4 degradation
-
WuG, Peng JB: Disease-causingmutations in KLHL3 impair its effect on WNK4 degradation. FEBS Lett 587: 1717-1722, 2013
-
(2013)
FEBS Lett
, vol.587
, pp. 1717-1722
-
-
Wu, G.1
Peng, J.B.2
-
21
-
-
84880376355
-
Emerging regulation and functions of autophagy
-
Boya P, Reggiori F, Codogno P: Emerging regulation and functions of autophagy. Nat Cell Biol 15: 713-720, 2013
-
(2013)
Nat Cell Biol
, vol.15
, pp. 713-720
-
-
Boya, P.1
Reggiori, F.2
Codogno, P.3
-
22
-
-
84872240012
-
MiR-30-regulated autophagy mediates angiotensin II-induced myocardial hypertrophy
-
Pan W, Zhong Y, Cheng C, Liu B, Wang L, Li A, Xiong L, Liu S: MiR-30-regulated autophagy mediates angiotensin II-induced myocardial hypertrophy. PLoS ONE 8: e53950, 2013
-
(2013)
PLoS ONE
, vol.8
, pp. e53950
-
-
Pan, W.1
Zhong, Y.2
Cheng, C.3
Liu, B.4
Wang, L.5
Li, A.6
Xiong, L.7
Liu, S.8
-
23
-
-
77955900101
-
ANG II promotes autophagy in podocytes
-
Yadav A, Vallabu S, Arora S, Tandon P, Slahan D, Teichberg S, Singhal PC: ANG II promotes autophagy in podocytes. Am J Physiol Cell Physiol 299: C488-C496, 2010
-
(2010)
Am J Physiol Cell Physiol
, vol.299
, pp. C488-C496
-
-
Yadav, A.1
Vallabu, S.2
Arora, S.3
Tandon, P.4
Slahan, D.5
Teichberg, S.6
Singhal, P.C.7
-
24
-
-
84901311762
-
Mitochondrial KATP channel involvement in angiotensin II-induced autophagy in vascular smooth muscle cells
-
Yu KY,Wang YP,Wang LH, Jian Y, Zhao XD, Chen JW,Murao K, ZhuW, Dong L, Wang GQ, Zhang GX: Mitochondrial KATP channel involvement in angiotensin II-induced autophagy in vascular smooth muscle cells. Basic Res Cardiol 109: 416, 2014
-
(2014)
Basic Res Cardiol
, vol.109
, pp. 416
-
-
Yu, K.Y.1
Wang, Y.P.2
Wang, L.H.3
Jian, Y.4
Zhao, X.D.5
Chen, J.W.6
Murao, K.7
Zhu, W.8
Dong, L.9
Wang, G.Q.10
Zhang, G.X.11
-
25
-
-
33748043980
-
Dietary electrolyte-driven responses in the renal WNK kinase pathway in vivo
-
O'Reilly M, Marshall E, Macgillivray T, Mittal M, Xue W, Kenyon CJ, Brown RW: Dietary electrolyte-driven responses in the renal WNK kinase pathway in vivo. J Am Soc Nephrol 17: 2402-2413, 2006
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2402-2413
-
-
O'Reilly, M.1
Marshall, E.2
Macgillivray, T.3
Mittal, M.4
Xue, W.5
Kenyon, C.J.6
Brown, R.W.7
-
26
-
-
84872137966
-
Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage
-
Bae SH, Sung SH, Oh SY, Lim JM, Lee SK, Park YN, Lee HE, Kang D, Rhee SG: Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage. Cell Metab 17: 73-84, 2013
-
(2013)
Cell Metab
, vol.17
, pp. 73-84
-
-
Bae, S.H.1
Sung, S.H.2
Oh, S.Y.3
Lim, J.M.4
Lee, S.K.5
Park, Y.N.6
Lee, H.E.7
Kang, D.8
Rhee, S.G.9
-
27
-
-
79959364986
-
Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: Association with sequestosome 1/p62
-
Myeku N, Figueiredo-Pereira ME: Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: Association with sequestosome 1/p62. J Biol Chem 286: 22426-22440, 2011
-
(2011)
J Biol Chem
, vol.286
, pp. 22426-22440
-
-
Myeku, N.1
Figueiredo-Pereira, M.E.2
-
28
-
-
84865143217
-
Effect of heterozygous deletion ofWNK1 on the WNK-OSR1/ SPAK-NCC/NKCC1/NKCC2 signal cascade in the kidney and blood vessels
-
Susa K, Kita S, Iwamoto T, Yang SS, Lin SH, Ohta A, Sohara E, Rai T, Sasaki S, Alessi DR, Uchida S: Effect of heterozygous deletion ofWNK1 on the WNK-OSR1/ SPAK-NCC/NKCC1/NKCC2 signal cascade in the kidney and blood vessels. Clin Exp Nephrol 16: 530-538, 2012
-
(2012)
Clin Exp Nephrol
, vol.16
, pp. 530-538
-
-
Susa, K.1
Kita, S.2
Iwamoto, T.3
Yang, S.S.4
Lin, S.H.5
Ohta, A.6
Sohara, E.7
Rai, T.8
Sasaki, S.9
Alessi, D.R.10
Uchida, S.11
-
29
-
-
84055219428
-
SPAK/OSR1 regulate NKCC1 and WNK activity: Analysis of WNK isoform interactions and activation by T-loop transautophosphorylation
-
Thastrup JO, Rafiqi FH, Vitari AC, Pozo-Guisado E, Deak M, Mehellou Y, Alessi DR: SPAK/OSR1 regulate NKCC1 and WNK activity: Analysis of WNK isoform interactions and activation by T-loop transautophosphorylation. Biochem J 441: 325-337, 2012
-
(2012)
Biochem J
, vol.441
, pp. 325-337
-
-
Thastrup, J.O.1
Rafiqi, F.H.2
Vitari, A.C.3
Pozo-Guisado, E.4
Deak, M.5
Mehellou, Y.6
Alessi, D.R.7
-
30
-
-
84964677935
-
A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo
-
Oi K, Sohara E, Rai T, Misawa M, ChigaM, Alessi DR, Sasaki S, Uchida S: A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo. Biol Open 1: 120-127, 2012
-
(2012)
Biol Open
, vol.1
, pp. 120-127
-
-
Oi, K.1
Sohara, E.2
Rai, T.3
Misawa, M.4
Chiga, M.5
Alessi, D.R.6
Sasaki, S.7
Uchida, S.8
-
31
-
-
80052340508
-
Acute insulin stimulation induces phosphorylation of the Na-Cl cotransporter in cultured distal mpkDCT cells and mouse kidney
-
Sohara E, Rai T, Yang SS, Ohta A, Naito S, Chiga M, Nomura N, Lin SH, Vandewalle A, Ohta E, Sasaki S, Uchida S: Acute insulin stimulation induces phosphorylation of the Na-Cl cotransporter in cultured distal mpkDCT cells and mouse kidney. PLoS ONE 6: e24277, 2011
-
(2011)
PLoS ONE
, vol.6
, pp. e24277
-
-
Sohara, E.1
Rai, T.2
Yang, S.S.3
Ohta, A.4
Naito, S.5
Chiga, M.6
Nomura, N.7
Lin, S.H.8
Vandewalle, A.9
Ohta, E.10
Sasaki, S.11
Uchida, S.12
-
32
-
-
78149310726
-
SPAK-knockout mice manifestGitelman syndrome and impaired vasoconstriction
-
Yang SS, Lo YF, Wu CC, Lin SW, Yeh CJ, Chu P, Sytwu HK, Uchida S, Sasaki S, Lin SH: SPAK-knockout mice manifestGitelman syndrome and impaired vasoconstriction. J Am Soc Nephrol 21: 1868-1877, 2010
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1868-1877
-
-
Yang, S.S.1
Lo, Y.F.2
Wu, C.C.3
Lin, S.W.4
Yeh, C.J.5
Chu, P.6
Sytwu, H.K.7
Uchida, S.8
Sasaki, S.9
Lin, S.H.10
-
33
-
-
70349581037
-
Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure
-
Ohta A, Rai T, Yui N, Chiga M, Yang SS, Lin SH, Sohara E, Sasaki S, Uchida S: Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressure. Hum Mol Genet 18: 3978-3986, 2009
-
(2009)
Hum Mol Genet
, vol.18
, pp. 3978-3986
-
-
Ohta, A.1
Rai, T.2
Yui, N.3
Chiga, M.4
Yang, S.S.5
Lin, S.H.6
Sohara, E.7
Sasaki, S.8
Uchida, S.9
|