Recombinant invasive Lactococcus lactis can transfer DNA vaccines either directly to dendritic cells or across an epithelial cell monolayer

Vaccine

Volumn 33, Issue 38, 2015, Pages 4807-4812

  de Azevedo, Marcela ^a   Meijerink, Marjolein ^b   Taverne, Nico ^b   Pereira, Vanessa Bastos ^a   LeBlanc, Jean Guy ^c   Azevedo, Vasco ^a   Miyoshi, Anderson ^a   Langella, Philippe ^d   Wells, Jerry M ^b   Chatel, Jean Marc ^d  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b WAGENINGEN UNIVERSITY   (Netherlands)

^c CENTRO DE REFERENCIA PARA LACTOBACILOS CERELA CONICET   (Argentina)

^d UMR1319 MICALIS   (France)

Author keywords

Dendritic cells; DNA delivery; Internalization; Lactococcus lactis; Listeria monocytogenes; Mutated internalin A; lactoglobulin

Indexed keywords

BETA LACTOGLOBULIN; DNA VACCINE; FIBRONECTIN BINDING PROTEIN; FIBRONECTIN BINDING PROTEIN A; INTERLEUKIN 10; INTERLEUKIN 12; INTERNALIN A; PLASMID DNA; UNCLASSIFIED DRUG; ADHESIN; BACTERIAL PROTEIN; DRUG CARRIER; FIBRONECTIN-BINDING PROTEINS, BACTERIAL; INTERNALIN PROTEIN, BACTERIA;

ANIMAL CELL; ARTICLE; BACTERIAL STRAIN; BONE MARROW DERIVED DENDRITIC CELL; CACO 2 CELL LINE; CELL SURVIVAL; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; DNA TRANSFER; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINE EPITHELIUM CELL; LACTOCOCCUS LACTIS; LISTERIA MONOCYTOGENES; MOUSE; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; TIGHT JUNCTION; ANIMAL; BAGG ALBINO MOUSE; CELL CULTURE; DENDRITIC CELL; ENDOCYTOSIS; EPITHELIUM CELL; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; PHYSIOLOGY;

ADHESINS, BACTERIAL; ANIMALS; BACTERIAL PROTEINS; CELLS, CULTURED; COCULTURE TECHNIQUES; DENDRITIC CELLS; DRUG CARRIERS; ENDOCYTOSIS; EPITHELIAL CELLS; LACTOCOCCUS LACTIS; MICE, INBRED BALB C; VACCINES, DNA;

EID: 84940719566     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2015.07.077     Document Type: Article

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