-
1
-
-
0037137903
-
Selection of high affinity human neutralizing antibodies to VEGFR2 from a large antibody phage display library for antiangiogenesis therapy
-
Lu D, Jimenez X, Zhang H, Bohlen P, Witte L, Zhu Z: Selection of high affinity human neutralizing antibodies to VEGFR2 from a large antibody phage display library for antiangiogenesis therapy. Int J Cancer 2002; 97: 393-399.
-
(2002)
Int J Cancer
, vol.97
, pp. 393-399
-
-
Lu, D.1
Jimenez, X.2
Zhang, H.3
Bohlen, P.4
Witte, L.5
Zhu, Z.6
-
2
-
-
0242353266
-
Tailoring in vitro selection for a picomolar affinity human antibody directed against vascular endothelial growth factor receptor 2 for enhanced neutralizing activity
-
Lu D, Shen J, Vil MD, Zhang H, Jimenez X, Bohlen P, Witte L, Zhu Z: Tailoring in vitro selection for a picomolar affinity human antibody directed against vascular endothelial growth factor receptor 2 for enhanced neutralizing activity. J Biol Chem 2003; 278: 43496-43507.
-
(2003)
J Biol Chem
, vol.278
, pp. 43496-43507
-
-
Lu, D.1
Shen, J.2
Vil, M.D.3
Zhang, H.4
Jimenez, X.5
Bohlen, P.6
Witte, L.7
Zhu, Z.8
-
3
-
-
85015497707
-
Clinical advances in the development of novel VEGFR2 inhibitors
-
Fontanella C, Ongaro E, Bolzonello S, Guardascione M, Fasola G, Aprile G: Clinical advances in the development of novel VEGFR2 inhibitors. Ann Transl Med 2014; 2: 123.
-
(2014)
Ann Transl Med
, vol.2
, pp. 123
-
-
Fontanella, C.1
Ongaro, E.2
Bolzonello, S.3
Guardascione, M.4
Fasola, G.5
Aprile, G.6
-
4
-
-
84908139963
-
Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): A double-blind, randomised phase 3 trial
-
Wilke H, Muro K, Van Cutsem EV, et al: Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): A double-blind, randomised phase 3 trial. Lancet Oncol 2014; 15: 1224-1235.
-
(2014)
Lancet Oncol
, vol.15
, pp. 1224-1235
-
-
Wilke, H.1
Muro, K.2
Van Cutsem, E.V.3
-
5
-
-
84892852372
-
Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): An international, randomised, multicentre, placebocontrolled, phase 3 trial
-
Fuchs CS, Tomasek J, Yong CJ, et al: Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): An international, randomised, multicentre, placebocontrolled, phase 3 trial. Lancet 2014; 383: 31-39.
-
(2014)
Lancet
, vol.383
, pp. 31-39
-
-
Fuchs, C.S.1
Tomasek, J.2
Yong, C.J.3
-
6
-
-
84916199585
-
Targeting vascular endothelial growth factor (VEGF) pathway in gastric cancer: Preclinical and clinical aspects
-
Abdel-Rahman, O: Targeting vascular endothelial growth factor (VEGF) pathway in gastric cancer: preclinical and clinical aspects. Crit Rev Oncol Hematol 2015; 93: 18-27.
-
(2015)
Crit Rev Oncol Hematol
, vol.93
, pp. 18-27
-
-
Abdel-Rahman, O.1
-
7
-
-
84923372373
-
Novel antiangiogenic drugs for the management of breast cancer: New approaches for an old issue
-
Bozza C, Fontanella C, Buoro V, Mansutti M, Aprile G: Novel antiangiogenic drugs for the management of breast cancer: new approaches for an old issue? Exp Rev Clin Pharmacol 2015; 8: 251-265.
-
(2015)
Exp Rev Clin Pharmacol
, vol.8
, pp. 251-265
-
-
Bozza, C.1
Fontanella, C.2
Buoro, V.3
Mansutti, M.4
Aprile, G.5
-
8
-
-
84908282604
-
Ramucirumab: Preclinical research and clinical development
-
Aprile G, Rijavec E, Fontanella C, Rihawi K, Grossi F: Ramucirumab: preclinical research and clinical development. Onco Targets Ther 2014; 7: 1997.
-
(2014)
Onco Targets Ther
, vol.7
, pp. 1997
-
-
Aprile, G.1
Rijavec, E.2
Fontanella, C.3
Rihawi, K.4
Grossi, F.5
-
9
-
-
84925548115
-
Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
-
Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA Group: Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. J Clin Epidemiol 2009; 62: 1006-1012.
-
(2009)
J Clin Epidemiol
, vol.62
, pp. 1006-1012
-
-
Moher, D.1
Liberati, A.2
Tetzlaff, J.3
Altman, D.G.4
-
12
-
-
84908278800
-
Final results of a phase 2 study of ramucirumab (RAM) plus erbulin (E) versus e in advanced metastatic breast cancer (MBC)
-
Yardley DA, Richards PD, Reeves JA, et al: Final results of a phase 2 study of ramucirumab (RAM) plus erbulin (E) versus E in advanced metastatic breast cancer (MBC). Abstract 1035. J Clin Oncol 2014; 32(suppl):S5.
-
(2014)
Abstract 1035. J Clin Oncol
, vol.32
, pp. S5
-
-
Yardley, D.A.1
Richards, P.D.2
Reeves, J.A.3
-
13
-
-
84908289623
-
Ramucirumab (RAM) plus FOLFOX as front-line therapy (Rx) for advanced gastric or esophageal adenocarcinoma (GE-AC): Randomized, double-blind, multicenter phase 2 trial
-
Yoon HH, Bendell JC, Braiteh FS, et al: Ramucirumab (RAM) plus FOLFOX as front-line therapy (Rx) for advanced gastric or esophageal adenocarcinoma (GE-AC): Randomized, double-blind, multicenter phase 2 trial. Abstract 4004. J Clin Oncol 2014; 32(suppl):S5.
-
(2014)
Abstract 4004. J Clin Oncol
, vol.32
, pp. S5
-
-
Yoon, H.H.1
Bendell, J.C.2
Braiteh, F.S.3
-
14
-
-
84924207092
-
Phase 2, randomized, open-label study of ramucirumab in combination with first-line pemetrexed and platinum chemotherapy in patients with nonsquamous, advanced/metastatic non-small cell lung cancer
-
Doebele RC, Spigel D, Tehfe M, et al: Phase 2, randomized, open-label study of ramucirumab in combination with first-line pemetrexed and platinum chemotherapy in patients with nonsquamous, advanced/metastatic non-small cell lung cancer. Cancer 2015; 121: 883-892.
-
(2015)
Cancer
, vol.121
, pp. 883-892
-
-
Doebele, R.C.1
Spigel, D.2
Tehfe, M.3
-
15
-
-
84947045086
-
-
(accessed March 31, 2015)
-
https://clinicaltrials. gov/ct2/show/results/ NCT01160744?term=ramucirumab&rank= 38§=X01256#all (accessed March 31, 2015).
-
-
-
-
16
-
-
84923605516
-
Ramucirumab as second-line treatment in patients with advanced hepatocellular carcinoma following first-line therapy with sorafenib: Results from the randomized phase III REACH trial
-
Zhu AX, Ryoo BY, Yen CJ, et al: Ramucirumab as second-line treatment in patients with advanced hepatocellular carcinoma following first-line therapy with sorafenib: results from the randomized phase III REACH trial. Ann Oncol 2014; 25(suppl 5):v1-v41.
-
(2014)
Ann Oncol
, vol.25
, pp. v1-v41
-
-
Zhu, A.X.1
Ryoo, B.Y.2
Yen, C.J.3
-
17
-
-
84906903314
-
Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): A multicentre, double-blind, randomised phase 3 trial
-
Garon EB, Ciuleanu TE, Arrieta O, et al: Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): A multicentre, double-blind, randomised phase 3 trial. Lancet 2014; 384: 665-673.
-
(2014)
Lancet
, vol.384
, pp. 665-673
-
-
Garon, E.B.1
Ciuleanu, T.E.2
Arrieta, O.3
-
18
-
-
84877689460
-
A phase II randomized study of cixutumumab (IMCA12: CIX) or ramucirumab (IMC-1121B: RAM) plus mitoxantrone (M) and prednisone (P) in patients (patients) with metastatic castrate-resistant prostate cancer (mCRPC) following disease progression (PD) on docetaxel (DCT) therapy (abstract)
-
Hussain M, Rathkopf DE, Liu G, et al: A phase II randomized study of cixutumumab (IMCA12: CIX) or ramucirumab (IMC-1121B: RAM) plus mitoxantrone (M) and prednisone (P) in patients (patients) with metastatic castrate-resistant prostate cancer (mCRPC) following disease progression (PD) on docetaxel (DCT) therapy (abstract). J Clin Oncol 2012; 30(suppl 5):97.
-
(2012)
J Clin Oncol
, vol.30
, pp. 97
-
-
Hussain, M.1
Rathkopf, D.E.2
Liu, G.3
-
19
-
-
84920919864
-
Primary results of ROSE/TRIO-12, a randomized placebo-controlled phase III trial evaluating the addition of ramucirumab to first-line docetaxel chemotherapy in metastatic breast cancer
-
Mackey JR, Ramos-Vazquez M, Lipatov O, et al: Primary results of ROSE/TRIO-12, a randomized placebo-controlled phase III trial evaluating the addition of ramucirumab to first-line docetaxel chemotherapy in metastatic breast cancer. J Clin Oncol 2015; 33: 141-148.
-
(2015)
J Clin Oncol
, vol.33
, pp. 141-148
-
-
Mackey, J.R.1
Ramos-Vazquez, M.2
Lipatov, O.3
-
20
-
-
84933673498
-
RAISE: A randomized, double-blind, multicenter phase III study of irinotecan, folinic acid, and 5-fluorouracil (FOLFIRI) plus ramucirumab (RAM) or placebo (PBO) in patients (patients) with metastatic colorectal carcinoma (CRC) progressive during or following first-line combination therapy with bevacizumab (bev), oxaliplatin (ox), and a fluoropyrimidine (fp)
-
Tabernero J, Cohn AL, Obermannova R, et al: RAISE: A randomized, double-blind, multicenter phase III study of irinotecan, folinic acid, and 5-fluorouracil (FOLFIRI) plus ramucirumab (RAM) or placebo (PBO) in patients (patients) with metastatic colorectal carcinoma (CRC) progressive during or following first-line combination therapy with bevacizumab (bev), oxaliplatin (ox), and a fluoropyrimidine (fp). J Clin Oncol 2015; 16: 499-508.
-
(2015)
J Clin Oncol
, vol.16
, pp. 499-508
-
-
Tabernero, J.1
Cohn, A.L.2
Obermannova, R.3
-
21
-
-
77953988924
-
Targeting the tumour vasculature: Insights from physiological angiogenesis
-
Chung AS, Lee J, Ferrara N: Targeting the tumour vasculature: insights from physiological angiogenesis. Nat Rev Cancer 2010; 10: 505-514.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 505-514
-
-
Chung, A.S.1
Lee, J.2
Ferrara, N.3
-
22
-
-
84925965379
-
Targeting vascular endothelial growth factor (VEGF) pathway in iodine-refractory differentiated thyroid carcinoma (DTC): From bench to bedside
-
Abdel-Rahman O: Targeting vascular endothelial growth factor (VEGF) pathway in iodine-refractory differentiated thyroid carcinoma (DTC): from bench to bedside. Crit Rev Oncol Hematol 2015; 94: 45-54.
-
(2015)
Crit Rev Oncol Hematol
, vol.94
, pp. 45-54
-
-
Abdel-Rahman, O.1
-
23
-
-
43249095919
-
Tumor angiogenesis
-
Kerbel RS: Tumor angiogenesis. N Engl J Med 2008; 358: 2039-2049.
-
(2008)
N Engl J Med
, vol.358
, pp. 2039-2049
-
-
Kerbel, R.S.1
-
24
-
-
84920948299
-
Vascular endothelial growth factor (VEGF) pathway and neuroendocrine neoplasms (NENs): Prognostic and therapeutic considerations
-
Abdel-Rahman O: Vascular endothelial growth factor (VEGF) pathway and neuroendocrine neoplasms (NENs): prognostic and therapeutic considerations. Tumor Biol 2014; 35: 10615-10625.
-
(2014)
Tumor Biol
, vol.35
, pp. 10615-10625
-
-
Abdel-Rahman, O.1
-
25
-
-
84947045116
-
-
(accessed April 24, 2015)
-
http://emedicine. medscape. com/article/ 238158-overview (accessed April 24, 2015).
-
-
-
-
26
-
-
84909602805
-
Incidence and risk of proteinuria with aflibercept in cancer patients: A meta-analysis
-
Peng L, Zhao Q, Ye X, Zhou Y, Hu D, Zheng S: Incidence and risk of proteinuria with aflibercept in cancer patients: A meta-analysis. PLoS One 2014; 9:e111839.
-
(2014)
PLoS One
, vol.9
, pp. e111839
-
-
Peng, L.1
Zhao, Q.2
Ye, X.3
Zhou, Y.4
Hu, D.5
Zheng, S.6
-
27
-
-
77955638572
-
Bevacizumab increases risk for severe proteinuria in cancer patients
-
Wu S, Kim C, Baer L, Zhu X: Bevacizumab increases risk for severe proteinuria in cancer patients. J Am Soc Nephrol 2010; 21: 1381-1389.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1381-1389
-
-
Wu, S.1
Kim, C.2
Baer, L.3
Zhu, X.4
-
28
-
-
84894636939
-
Renal adverse effects of sunitinib and its clinical significance: A single-center experience in Korea
-
Baek S, Kim H, Lee J, et al: Renal adverse effects of sunitinib and its clinical significance: A single-center experience in Korea. Korean J Intern Med 2014; 29: 40-48.
-
(2014)
Korean J Intern Med
, vol.29
, pp. 40-48
-
-
Baek, S.1
Kim, H.2
Lee, J.3
-
29
-
-
0037370325
-
Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases
-
Eremina V, Sood M, Haigh J, Nagy A, Lajoie G, et al: Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J Clin Invest 2003; 111: 707-716.
-
(2003)
J Clin Invest
, vol.111
, pp. 707-716
-
-
Eremina, V.1
Sood, M.2
Haigh, J.3
Nagy, A.4
Lajoie, G.5
-
30
-
-
72449132908
-
VEGF signalling inhibitioninduced proteinuria: Mechanisms, significance and management
-
Izzedine H, Massard C, Spano JP, Goldwasser F, Khayat D, et al: VEGF signalling inhibitioninduced proteinuria: mechanisms, significance and management. Eur J Cancer 2010; 46: 439-448.
-
(2010)
Eur J Cancer
, vol.46
, pp. 439-448
-
-
Izzedine, H.1
Massard, C.2
Spano, J.P.3
Goldwasser, F.4
Khayat, D.5
-
32
-
-
84923658464
-
Timely diagnosis and treatment essential in glomerulonephritis
-
Lewis G, Maxwell AP: Timely diagnosis and treatment essential in glomerulonephritis. Practitioner 2015; 259: 13-17.
-
(2015)
Practitioner
, vol.259
, pp. 13-17
-
-
Lewis, G.1
Maxwell, A.P.2
-
33
-
-
84930475321
-
Predictors of rapid progression of glomerular and nonglomerular kidney disease in children and adolescents: The Chronic Kidney Disease in Children (CKiD) cohort
-
Warady BA, Abraham AG, Schwartz GJ, Wong CS, Muñoz A, Betoko A, Furth S: Predictors of rapid progression of glomerular and nonglomerular kidney disease in children and adolescents: The Chronic Kidney Disease in Children (CKiD) cohort. Am J Kidney Dis 2015; 65: 878-888.
-
(2015)
Am J Kidney Dis
, vol.65
, pp. 878-888
-
-
Warady, B.A.1
Abraham, A.G.2
Schwartz, G.J.3
Wong, C.S.4
Muñoz, A.5
Betoko, A.6
Furth, S.7
-
34
-
-
40149083478
-
Slowing nephropathy progression: Focus on proteinuria reduction
-
Bakris GL: Slowing nephropathy progression: focus on proteinuria reduction. Clin J Am Soc Nephrol 2008; 3(suppl 1):S3-S10.
-
(2008)
Clin J Am Soc Nephrol
, vol.3
, pp. S3-S10
-
-
Bakris, G.L.1
-
35
-
-
2442680120
-
Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: Lessons from RENAAL
-
De Zeeuw D, Remuzzi G, Parving HH, Keane WF, Zhang Z, Shahinfar S, et al: Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: lessons from RENAAL. Kidney Int 2004; 65: 2309-2320.
-
(2004)
Kidney Int
, vol.65
, pp. 2309-2320
-
-
De Zeeuw, D.1
Remuzzi, G.2
Parving, H.H.3
Keane, W.F.4
Zhang, Z.5
Shahinfar, S.6
-
36
-
-
34548301629
-
Renin angiotensin system blockade in kidney transplantation: A systematic review of the evidence
-
Hiremath S, Fergusson D, Doucette S, Mulay AV, Knoll GA: Renin angiotensin system blockade in kidney transplantation: A systematic review of the evidence. Am J Transplant 2007; 7: 2350-2360.
-
(2007)
Am J Transplant
, vol.7
, pp. 2350-2360
-
-
Hiremath, S.1
Fergusson, D.2
Doucette, S.3
Mulay, A.V.4
Knoll, G.A.5
-
37
-
-
84922481556
-
Treatment of hypertension and renal injury induced by the angiogenesis inhibitor sunitinib: Preclinical study
-
Lankhorst S, Kappers MH, van Esch JH, Smedts FM, Sleijfer S, Mathijssen RH, et al: Treatment of hypertension and renal injury induced by the angiogenesis inhibitor sunitinib: preclinical study. Hypertension 2014; 64: 1282-1289.
-
(2014)
Hypertension
, vol.64
, pp. 1282-1289
-
-
Lankhorst, S.1
Kappers, M.H.2
Van Esch, J.H.3
Smedts, F.M.4
Sleijfer, S.5
Mathijssen, R.H.6
-
38
-
-
3042819708
-
K/DOQI clinical practice guidelines on hypertension and antihypertensive agents in chronic kidney disease
-
Kidney Disease Outcomes Quality Initiative
-
Kidney Disease Outcomes Quality Initiative: K/DOQI clinical practice guidelines on hypertension and antihypertensive agents in chronic kidney disease. Am J Kidney Dis 2004; 43(suppl 1):S1-290.
-
(2004)
Am J Kidney Dis
, vol.43
, pp. S1-290
-
-
-
39
-
-
33845656482
-
Angiotensin-converting enzyme inhibitors for bevacizumab-induced hypertension
-
Dincer M, Altundag K: Angiotensin-converting enzyme inhibitors for bevacizumab-induced hypertension. Ann Pharmacother 2006; 40: 2278-2279.
-
(2006)
Ann Pharmacother
, vol.40
, pp. 2278-2279
-
-
Dincer, M.1
Altundag, K.2
-
40
-
-
84933518022
-
Use of angiotensin-converting enzyme inhibitors in the prophylaxis of anthracycline or trastuzumabrelated cardiac dysfunction: Preclinical and clinical considerations
-
Abdel-Rahman O, Alorabi M: Use of angiotensin-converting enzyme inhibitors in the prophylaxis of anthracycline or trastuzumabrelated cardiac dysfunction: preclinical and clinical considerations. Expert Rev Anticancer Ther 2015; 15: 829-837.
-
(2015)
Expert Rev Anticancer Ther
, vol.15
, pp. 829-837
-
-
Abdel-Rahman, O.1
Alorabi, M.2
-
41
-
-
84947042085
-
-
(accessed April 1, 2015)
-
http://pi. lilly. com/us/cyramza-pi. pdf (accessed April 1, 2015).
-
-
-
|