메뉴 건너뛰기




Volumn 8, Issue 7, 2015, Pages 10235-10247

Clinicopathological and prognostic significance of high Ki-67 labeling index in hepatocellular carcinoma patients: A meta-analysis

Author keywords

Clinicopathological features; Hepatocellular carcinoma (HCC); Ki 67; Meta analysis; Prognostic value

Indexed keywords

KI 67 ANTIGEN;

EID: 84940644730     PISSN: None     EISSN: 19405901     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (88)

References (79)
  • 1
    • 84926652915 scopus 로고    scopus 로고
    • Analysis of prognostic factors for survival after hepatectomy for hepatocellular carcinoma based on a bayesian network
    • Cai ZQ, Si SB, Chen C, Zhao Y, Ma YY, Wang L, Geng ZM. Analysis of prognostic factors for survival after hepatectomy for hepatocellular carcinoma based on a bayesian network. PLoS One 2015; 10: e0120805.
    • (2015) PLoS One , vol.10
    • Cai, Z.Q.1    Si, S.B.2    Chen, C.3    Zhao, Y.4    Ma, Y.Y.5    Wang, L.6    Geng, Z.M.7
  • 4
    • 34250020201 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis
    • El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007; 132: 2557-76.
    • (2007) Gastroenterology , vol.132 , pp. 2557-2576
    • El-Serag, H.B.1    Rudolph, K.L.2
  • 5
    • 58149376548 scopus 로고    scopus 로고
    • Molecular mechanisms of hepatocellular carcinoma
    • Aravalli RN, Steer CJ, Cressman EN. Molecular mechanisms of hepatocellular carcinoma. Hepatology 2008; 48: 2047-63.
    • (2008) Hepatology , vol.48 , pp. 2047-2063
    • Aravalli, R.N.1    Steer, C.J.2    Cressman, E.N.3
  • 6
    • 0025810796 scopus 로고
    • Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67
    • Gerdes J, Li L, Schlueter C, Duchrow M, Wohlenberg C, Gerlach C, Stahmer I, Kloth S, Brandt E, Flad HD. Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67. Am J Pathol 1991; 138: 867-73.
    • (1991) Am J Pathol , vol.138 , pp. 867-873
    • Gerdes, J.1    Li, L.2    Schlueter, C.3    Duchrow, M.4    Wohlenberg, C.5    Gerlach, C.6    Stahmer, I.7    Kloth, S.8    Brandt, E.9    Flad, H.D.10
  • 7
    • 0021212003 scopus 로고
    • Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67
    • Gerdes J, Lemke H, Baisch H, Wacker HH, Schwab U, Stein H. Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol 1984; 133: 1710-5.
    • (1984) J Immunol , vol.133 , pp. 1710-1715
    • Gerdes, J.1    Lemke, H.2    Baisch, H.3    Wacker, H.H.4    Schwab, U.5    Stein, H.6
  • 8
    • 33750846321 scopus 로고    scopus 로고
    • The clinical value of Ki-67/MIB-1 labeling index in human astrocytomas
    • Johannessen AL, Torp SH. The clinical value of Ki-67/MIB-1 labeling index in human astrocytomas. Pathol Oncol Res 2006; 12: 143-7.
    • (2006) Pathol Oncol Res , vol.12 , pp. 143-147
    • Johannessen, A.L.1    Torp, S.H.2
  • 9
    • 0032892199 scopus 로고    scopus 로고
    • Angiogenesis, p53, bcl-2 and Ki-67 in the progression of prostate cancer after radical prostatectomy
    • Moul JW. Angiogenesis, p53, bcl-2 and Ki-67 in the progression of prostate cancer after radical prostatectomy. Eur Urol 1999; 35: 399-407.
    • (1999) Eur Urol , vol.35 , pp. 399-407
    • Moul, J.W.1
  • 10
    • 77949677930 scopus 로고    scopus 로고
    • Sialoblastoma: Utility of Ki-67 and p53 as a prognostic tool and review of literature
    • Patil DT, Chou PM. Sialoblastoma: utility of Ki-67 and p53 as a prognostic tool and review of literature. Pediatr Dev Pathol 2010; 13: 32-8.
    • (2010) Pediatr Dev Pathol , vol.13 , pp. 32-38
    • Patil, D.T.1    Chou, P.M.2
  • 11
    • 60749115714 scopus 로고    scopus 로고
    • Predicting prognosis in gastroentero-pancreatic neuroendocrine tumors: An overview and the value of Ki-67 im munostaining
    • Jamali M, Chetty R. Predicting prognosis in gastroentero-pancreatic neuroendocrine tumors: an overview and the value of Ki-67 im munostaining. Endocr Pathol 2008; 19: 282-8.
    • (2008) Endocr Pathol , vol.19 , pp. 282-288
    • Jamali, M.1    Chetty, R.2
  • 12
    • 84871073608 scopus 로고    scopus 로고
    • Clinical impact of ki-67 labeling index in non-small cell lung cancer
    • Jakobsen JN, Sorensen JB. Clinical impact of ki-67 labeling index in non-small cell lung cancer. Lung Cancer 2013; 79: 1-7.
    • (2013) Lung Cancer , vol.79 , pp. 1-7
    • Jakobsen, J.N.1    Sorensen, J.B.2
  • 13
    • 84878344513 scopus 로고    scopus 로고
    • Ki67 and proliferation in breast cancer
    • Pathmanathan N, Balleine RL. Ki67 and proliferation in breast cancer. J Clin Pathol 2013; 66: 512-6.
    • (2013) J Clin Pathol , vol.66 , pp. 512-516
    • Pathmanathan, N.1    Balleine, R.L.2
  • 17
    • 84899474728 scopus 로고    scopus 로고
    • Ki-67 is a valuable prognostic predictor of lymphoma but its utility varies in lymphoma subtypes: Evidence from a systematic meta-analysis
    • He X, Chen Z, Fu T, Jin X, Yu T, Liang Y, Zhao X, Huang L. Ki-67 is a valuable prognostic predictor of lymphoma but its utility varies in lymphoma subtypes: evidence from a systematic meta-analysis. BMC Cancer 2014; 14: 153.
    • (2014) BMC Cancer , vol.14 , pp. 153
    • He, X.1    Chen, Z.2    Fu, T.3    Jin, X.4    Yu, T.5    Liang, Y.6    Zhao, X.7    Huang, L.8
  • 18
    • 84925411798 scopus 로고    scopus 로고
    • Ki-67 is a valuable prognostic factor in gliomas: Evidence from a systematic review and meta-analysis
    • Chen WJ, He DS, Tang RX, Ren FH, Chen G. Ki-67 is a valuable prognostic factor in gliomas: evidence from a systematic review and meta-analysis. Asian Pac J Cancer Prev 2015; 16: 411-20.
    • (2015) Asian Pac J Cancer Prev , vol.16 , pp. 411-420
    • Chen, W.J.1    He, D.S.2    Tang, R.X.3    Ren, F.H.4    Chen, G.5
  • 19
    • 84925650270 scopus 로고    scopus 로고
    • The Prognostic Role of Ki-67/MIB-1 in Cervical Cancer: A Systematic Review with Meta-Analysis
    • Pan D, Wei K, Ling Y, Su S, Zhu M, Chen G. The Prognostic Role of Ki-67/MIB-1 in Cervical Cancer: A Systematic Review with Meta-Analysis. Med Sci Monit 2015; 21: 882-9.
    • (2015) Med Sci Monit , vol.21 , pp. 882-889
    • Pan, D.1    Wei, K.2    Ling, Y.3    Su, S.4    Zhu, M.5    Chen, G.6
  • 22
    • 82755162458 scopus 로고    scopus 로고
    • Tissue expression of squamous cellular carcinoma antigen and Ki67 in hepatocellular carcinoma-correlation with prognosis: A historical prospective study
    • Schmilovitz-Weiss H, Tobar A, Halpern M, Levy I, Shabtai E, Ben-Ari Z. Tissue expression of squamous cellular carcinoma antigen and Ki67 in hepatocellular carcinoma-correlation with prognosis: a historical prospective study. Diagno Pathol 2011; 6: 121.
    • (2011) Diagno Pathol , vol.6 , pp. 121
    • Schmilovitz-Weiss, H.1    Tobar, A.2    Halpern, M.3    Levy, I.4    Shabtai, E.5    Ben-Ari, Z.6
  • 23
    • 28844438441 scopus 로고    scopus 로고
    • Growth index, assessed with Ki-67 and ssDNA labeling; a significant prognosticator for patients undergoing curative resection for hepatocellular carcinoma
    • Morinaga S, Ishiwa N, Noguchi Y, Yamamoto Y, Rino Y, Imada T, Takanashi Y, Akaike M, Sugimasa Y, Takemiya S. Growth index, assessed with Ki-67 and ssDNA labeling; a significant prognosticator for patients undergoing curative resection for hepatocellular carcinoma. J Surg Oncol 2005; 92: 331-6.
    • (2005) J Surg Oncol , vol.92 , pp. 331-336
    • Morinaga, S.1    Ishiwa, N.2    Noguchi, Y.3    Yamamoto, Y.4    Rino, Y.5    Imada, T.6    Takanashi, Y.7    Akaike, M.8    Sugimasa, Y.9    Takemiya, S.10
  • 24
    • 83655203595 scopus 로고    scopus 로고
    • Effects of risk factors and Ki-67 on rates of recurrence on patients who have undergone liver transplant for hepatocellular carcinoma
    • Ktas S, Karakayali H, Moray G, Ozdemir H, Haberal M. Effects of risk factors and Ki-67 on rates of recurrence on patients who have undergone liver transplant for hepatocellular carcinoma. Transplant Proc 2011; 43: 3807-12.
    • (2011) Transplant Proc , vol.43 , pp. 3807-3812
    • Ktas, S.1    Karakayali, H.2    Moray, G.3    Ozdemir, H.4    Haberal, M.5
  • 25
    • 0032583387 scopus 로고    scopus 로고
    • Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints
    • Parmar MK, Torri V, Stewart L. Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. Stat Med 1998; 17: 2815-34.
    • (1998) Stat Med , vol.17 , pp. 2815-2834
    • Parmar, M.K.1    Torri, V.2    Stewart, L.3
  • 26
    • 0030693603 scopus 로고    scopus 로고
    • Quantitative synthesis in systematic reviews
    • Lau J, Ioannidis JP, Schmid CH. Quantitative synthesis in systematic reviews. Ann Intern Med 1997; 127: 820-6.
    • (1997) Ann Intern Med , vol.127 , pp. 820-826
    • Lau, J.1    Ioannidis, J.P.2    Schmid, C.H.3
  • 27
    • 84955693994 scopus 로고    scopus 로고
    • Microvessel density in hepatocellular carcinoma: Prognostic significance and review of the previous published work
    • [Epub ahead of print]
    • Murakami K, Kasajima A, Kawagishi N, Ohuchi N, Sasano H. Microvessel density in hepatocellular carcinoma: Prognostic significance and review of the previous published work. Hepatol Res 2015; [Epub ahead of print].
    • (2015) Hepatol Res
    • Murakami, K.1    Kasajima, A.2    Kawagishi, N.3    Ohuchi, N.4    Sasano, H.5
  • 30
    • 84859061223 scopus 로고    scopus 로고
    • Loss of Wnt5a and Ror2 protein in hepatocellular carcinoma associated with poor prognosis
    • Geng M, Cao YC, Chen YJ, Jiang H, Bi LQ, Liu XH. Loss of Wnt5a and Ror2 protein in hepatocellular carcinoma associated with poor prognosis. World J Gastroenterol 2012; 18: 1328-38.
    • (2012) World J Gastroenterol , vol.18 , pp. 1328-1338
    • Geng, M.1    Cao, Y.C.2    Chen, Y.J.3    Jiang, H.4    Bi, L.Q.5    Liu, X.H.6
  • 32
    • 84952719678 scopus 로고    scopus 로고
    • High expression of vacuolar protein sorting 4B (VPS4B) is associated with accelerated cell proliferation and poor prognosis in human hepatocellular carcinoma
    • Jiang D, Hu B, Wei L, Xiong Y, Wang G, Ni T, Zong C, Ni R, Lu C. High expression of vacuolar protein sorting 4B (VPS4B) is associated with accelerated cell proliferation and poor prognosis in human hepatocellular carcinoma. Pathol Res Prac 2015; 211: 240-7.
    • (2015) Pathol Res Prac , vol.211 , pp. 240-247
    • Jiang, D.1    Hu, B.2    Wei, L.3    Xiong, Y.4    Wang, G.5    Ni, T.6    Zong, C.7    Ni, R.8    Lu, C.9
  • 34
    • 84907594297 scopus 로고    scopus 로고
    • The downregulation of ErbB3 binding protein 1 (EBP1) is associated with poor prognosis and enhanced cell proliferation in hepatocellular carcinoma
    • Hu B, Xiong Y, Ni R, Wei L, Jiang D, Wang G, Wu D, Xu T, Zhao F, Zhu M, Wan C. The downregulation of ErbB3 binding protein 1 (EBP1) is associated with poor prognosis and enhanced cell proliferation in hepatocellular carcinoma. Mol Cell Biochem 2014; 396: 175-85.
    • (2014) Mol Cell Biochem , vol.396 , pp. 175-185
    • Hu, B.1    Xiong, Y.2    Ni, R.3    Wei, L.4    Jiang, D.5    Wang, G.6    Wu, D.7    Xu, T.8    Zhao, F.9    Zhu, M.10    Wan, C.11
  • 35
    • 84922058973 scopus 로고    scopus 로고
    • Chaperonin containing TCP1, subunit 8 (CCT8) is upregulated in hepatocellular carcinoma and promotes HCC proliferation
    • Huang X, Wang X, Cheng C, Cai J, He S, Wang H, Liu F, Zhu C, Ding Z, Huang X, Zhang T, Zhang Y. Chaperonin containing TCP1, subunit 8 (CCT8) is upregulated in hepatocellular carcinoma and promotes HCC proliferation. APMIS 2014; 122: 1070-9.
    • (2014) APMIS , vol.122 , pp. 1070-1079
    • Huang, X.1    Wang, X.2    Cheng, C.3    Cai, J.4    He, S.5    Wang, H.6    Liu, F.7    Zhu, C.8    Ding, Z.9    Huang, X.10    Zhang, T.11    Zhang, Y.12
  • 36
    • 84898804154 scopus 로고    scopus 로고
    • Expression and prognostic significance of p21-activated kinase 6 in hepatocellular carcinoma
    • Chen H, Miao J, Li H, Wang C, Li J, Zhu Y, Wang J, Wu X, Qiao H. Expression and prognostic significance of p21-activated kinase 6 in hepatocellular carcinoma. J Surg Res 2014; 189: 81-8.
    • (2014) J Surg Res , vol.189 , pp. 81-88
    • Chen, H.1    Miao, J.2    Li, H.3    Wang, C.4    Li, J.5    Zhu, Y.6    Wang, J.7    Wu, X.8    Qiao, H.9
  • 39
    • 84877911775 scopus 로고    scopus 로고
    • High SKIP expression is correlated with poor prognosis and cell proliferation of hepatocellular carcinoma
    • Liu G, Huang X, Cui X, Zhang J, Wei L, Ni R, Lu C. High SKIP expression is correlated with poor prognosis and cell proliferation of hepatocellular carcinoma. Med Oncol 2013; 30: 537.
    • (2013) Med Oncol , vol.30 , pp. 537
    • Liu, G.1    Huang, X.2    Cui, X.3    Zhang, J.4    Wei, L.5    Ni, R.6    Lu, C.7
  • 40
    • 84884208999 scopus 로고    scopus 로고
    • Increased alpha-tubulin1b expression indicates poor prognosis and resistance to chemotherapy in hepatocellular carcinoma
    • Lu C, Zhang J, He S, Wan C, Shan A, Wang Y, Yu L, Liu G, Chen K, Shi J, Zhang Y, Ni R. Increased alpha-tubulin1b expression indicates poor prognosis and resistance to chemotherapy in hepatocellular carcinoma. Dig Dis Sci 2013; 58: 2713-20.
    • (2013) Dig Dis Sci , vol.58 , pp. 2713-2720
    • Lu, C.1    Zhang, J.2    He, S.3    Wan, C.4    Shan, A.5    Wang, Y.6    Yu, L.7    Liu, G.8    Chen, K.9    Shi, J.10    Zhang, Y.11    Ni, R.12
  • 41
    • 84879585978 scopus 로고    scopus 로고
    • The correlation between insulin-like growth factor II mRNA binding protein 3 expression in hepatocellular carcinoma and prognosis
    • Chen LT, Lin LJ, Zheng LL. The correlation between insulin-like growth factor II mRNA binding protein 3 expression in hepatocellular carcinoma and prognosis. Hepatogastroenterology 2013; 60: 553-6.
    • (2013) Hepatogastroenterology , vol.60 , pp. 553-556
    • Chen, L.T.1    Lin, L.J.2    Zheng, L.L.3
  • 42
    • 84863463886 scopus 로고    scopus 로고
    • Clinical and biological significance of never in mitosis gene A-related kinase 6 (NEK6) expression in hepatic cell cancer
    • Cao X, Xia Y, Yang J, Jiang J, Chen L, Ni R, Li L, Gu Z. Clinical and biological significance of never in mitosis gene A-related kinase 6 (NEK6) expression in hepatic cell cancer. Pathol Oncol Res 2012; 18: 201-7.
    • (2012) Pathol Oncol Res , vol.18 , pp. 201-207
    • Cao, X.1    Xia, Y.2    Yang, J.3    Jiang, J.4    Chen, L.5    Ni, R.6    Li, L.7    Gu, Z.8
  • 43
    • 79952251697 scopus 로고    scopus 로고
    • Phosphorylated p27Kip1 on Thr157 is an important prognosis in human hepatocellular carcinoma in vivo and in vitro
    • He S, Lu M, Xue W, Wang Y, Zhao Y, Gao S, Ke Q, Liu Y, Li P, Cui X, Cheng C, Shen A. Phosphorylated p27Kip1 on Thr157 is an important prognosis in human hepatocellular carcinoma in vivo and in vitro. Med Oncol 2011; 28: 94-104.
    • (2011) Med Oncol , vol.28 , pp. 94-104
    • He, S.1    Lu, M.2    Xue, W.3    Wang, Y.4    Zhao, Y.5    Gao, S.6    Ke, Q.7    Liu, Y.8    Li, P.9    Cui, X.10    Cheng, C.11    Shen, A.12
  • 45
    • 34250858888 scopus 로고    scopus 로고
    • Altered p-STAT3 (tyr705) expression is associated with histological grading and intratumour microvessel density in hepatocellular carcinoma
    • Yang SF, Wang SN, Wu CF, Yeh YT, Chai CY, Chunag SC, Sheen MC, Lee KT. Altered p-STAT3 (tyr705) expression is associated with histological grading and intratumour microvessel density in hepatocellular carcinoma. J Clin Pathol 2007; 60: 642-8.
    • (2007) J Clin Pathol , vol.60 , pp. 642-648
    • Yang, S.F.1    Wang, S.N.2    Wu, C.F.3    Yeh, Y.T.4    Chai, C.Y.5    Chunag, S.C.6    Sheen, M.C.7    Lee, K.T.8
  • 48
    • 12344289067 scopus 로고    scopus 로고
    • Akt phosphorylation is a risk factor for early disease recurrence and poor prognosis in hepatocellular carcinoma
    • Nakanishi K, Sakamoto M, Yamasaki S, Todo S, Hirohashi S. Akt phosphorylation is a risk factor for early disease recurrence and poor prognosis in hepatocellular carcinoma. Cancer 2005; 103: 307-12.
    • (2005) Cancer , vol.103 , pp. 307-312
    • Nakanishi, K.1    Sakamoto, M.2    Yamasaki, S.3    Todo, S.4    Hirohashi, S.5
  • 51
    • 84937511095 scopus 로고    scopus 로고
    • Expression of proteins associated with hypoxia and Wnt pathway activation is of prognostic significance in hepatocellular carcinoma
    • Srivastava S, Thakkar B, Yeoh KG, Ho KY, Teh M, Soong R, Salto-Tellez M. Expression of proteins associated with hypoxia and Wnt pathway activation is of prognostic significance in hepatocellular carcinoma. Virchows Archiv 2015; 466: 541-8.
    • (2015) Virchows Archiv , vol.466 , pp. 541-548
    • Srivastava, S.1    Thakkar, B.2    Yeoh, K.G.3    Ho, K.Y.4    Teh, M.5    Soong, R.6    Salto-Tellez, M.7
  • 52
    • 20344387260 scopus 로고    scopus 로고
    • Construction and clinical significance of a predictive system for prognosis of hepatocellular carcinoma
    • Cui J, Dong BW, Liang P, Yu XL, Yu DJ. Construction and clinical significance of a predictive system for prognosis of hepatocellular carcinoma. World J Gastroenterol 2005; 11: 3027-33.
    • (2005) World J Gastroenterol , vol.11 , pp. 3027-3033
    • Cui, J.1    Dong, B.W.2    Liang, P.3    Yu, X.L.4    Yu, D.J.5
  • 53
    • 0042334830 scopus 로고    scopus 로고
    • Loss of p16 contributes to p27 sequestration by cyclin D(1)-cyclin-dependent kinase 4 complexes and poor prognosis in hepatocellular carcinoma
    • Matsuda Y, Ichida T, Genda T, Yamagiwa S, Aoyagi Y, Asakura H. Loss of p16 contributes to p27 sequestration by cyclin D(1)-cyclin-dependent kinase 4 complexes and poor prognosis in hepatocellular carcinoma. Clin Cancer Res 2003; 9: 3389-96.
    • (2003) Clin Cancer Res , vol.9 , pp. 3389-3396
    • Matsuda, Y.1    Ichida, T.2    Genda, T.3    Yamagiwa, S.4    Aoyagi, Y.5    Asakura, H.6
  • 60
    • 0033916771 scopus 로고    scopus 로고
    • Expression and prognostic role of cyclin-dependent kinase 1 (cdc2) in hepatocellular carcinoma
    • Ito Y, Takeda T, Sakon M, Monden M, Tsujimoto M, Matsuura N. Expression and prognostic role of cyclin-dependent kinase 1 (cdc2) in hepatocellular carcinoma. Oncology 2000; 59: 68-74.
    • (2000) Oncology , vol.59 , pp. 68-74
    • Ito, Y.1    Takeda, T.2    Sakon, M.3    Monden, M.4    Tsujimoto, M.5    Matsuura, N.6
  • 63
    • 0031936144 scopus 로고    scopus 로고
    • Expression of proliferation associated antigens and detection of numerical chromosome aberrations in primary human liver tumours: Relevance to tumour characteristics and prognosis
    • Nolte M, Werner M, Nasarek A, Bektas H, von Wasielewski R, Klempnauer J, Georgii A. Expression of proliferation associated antigens and detection of numerical chromosome aberrations in primary human liver tumours: relevance to tumour characteristics and prognosis. J Clin Pathol 1998; 51: 47-51.
    • (1998) J Clin Pathol , vol.51 , pp. 47-51
    • Nolte, M.1    Werner, M.2    Nasarek, A.3    Bektas, H.4    von Wasielewski, R.5    Klempnauer, J.6    Georgii, A.7
  • 64
    • 84940653455 scopus 로고    scopus 로고
    • Expression of CD34, 8-OHdG and Ki67 in patients with HBV-HCC and their significances to prognosis of HCC
    • Zhang L, Li SM, Zhang HJ, Wu YJ. Expression of CD34, 8-OHdG and Ki67 in patients with HBV-HCC and their significances to prognosis of HCC. Cancer Research on Prevention and Treament 2012; 39: 547-50.
    • (2012) Cancer Research on Prevention and Treament , vol.39 , pp. 547-550
    • Zhang, L.1    Li, S.M.2    Zhang, H.J.3    Wu, Y.J.4
  • 67
    • 84940653368 scopus 로고    scopus 로고
    • Significance of Ki-67 antigen expression in hepatocellular carcinoma
    • Han SH, Huang JF. Significance of Ki-67 antigen expression in hepatocellular carcinoma. Chinese Journal of General Surgery 2000; 9: 42-5.
    • (2000) Chinese Journal of General Surgery , vol.9 , pp. 42-45
    • Han, S.H.1    Huang, J.F.2
  • 69
    • 84940639793 scopus 로고    scopus 로고
    • The significance of p53, Ki-67 expression in hepatocellular carcinoma tissue
    • Pang XF, Wang ZS, Sun SG, Wu LQ. The significance of p53, Ki-67 expression in hepatocellular carcinoma tissue. Shandong Medical Journal 2011; 51: 34-5.
    • (2011) Shandong Medical Journal , vol.51 , pp. 34-35
    • Pang, X.F.1    Wang, Z.S.2    Sun, S.G.3    Wu, L.Q.4
  • 70
    • 84940654766 scopus 로고    scopus 로고
    • Significance of Ki-67 expression in the prognosis of patients with short-term recurrence of hepatocellular carcinoma after radical resection hepatectomy
    • Pang XF, Wang ZS, Wu LQ. Significance of Ki-67 expression in the prognosis of patients with short-term recurrence of hepatocellular carcinoma after radical resection hepatectomy. Chinese Journal of hepatic surgery (Electronic Edition) 2012; 1: 123-8.
    • (2012) Chinese Journal of hepatic surgery (Electronic Edition) , vol.1 , pp. 123-128
    • Pang, X.F.1    Wang, Z.S.2    Wu, L.Q.3
  • 74
    • 84940668806 scopus 로고    scopus 로고
    • Analysis of the related factors which affect tumor biological behavior and prognosis in hepatocellular carcinoma
    • Zhang YR, Xue L, He P, Che LH. Analysis of the related factors which affect tumor biological behavior and prognosis in hepatocellular carcinoma. Journal of Sun Yat-sen University (Medical Sciences) 2007; 28: 19-21.
    • (2007) Journal of Sun Yat-sen University (Medical Sciences) , vol.28 , pp. 19-21
    • Zhang, Y.R.1    Xue, L.2    He, P.3    Che, L.H.4
  • 77
    • 0020694123 scopus 로고
    • Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation
    • Gerdes J, Schwab U, Lemke H, Stein H. Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. Int J Cancer 1983; 31: 13-20.
    • (1983) Int J Cancer , vol.31 , pp. 13-20
    • Gerdes, J.1    Schwab, U.2    Lemke, H.3    Stein, H.4
  • 78
    • 1642295096 scopus 로고    scopus 로고
    • Assessing the probability that a positive report is false: An approach for molecular epidemiology studies
    • Wacholder S, Chanock S, Garcia-Closas M, El Ghormli L, Rothman N. Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J Natl Cancer Inst 2004; 96: 434-42.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 434-442
    • Wacholder, S.1    Chanock, S.2    Garcia-Closas, M.3    El Ghormli, L.4    Rothman, N.5
  • 79
    • 4143145303 scopus 로고    scopus 로고
    • Meta-analysis of genetic association studies
    • Munafo MR, Flint J. Meta-analysis of genetic association studies. Trends Gene : TIG 2004; 20: 439-44.
    • (2004) Trends Gene : TIG , vol.20 , pp. 439-444
    • Munafo, M.R.1    Flint, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.