Roles of melatonin in abiotic stress resistance in plants

Journal of Experimental Botany

Volumn 66, Issue 3, 2015, Pages 647-656

  Zhang, Na ^a   Sun, Qianqian ^a   Zhang, Haijun ^a   Cao, Yunyun ^a   Weeda, Sarah ^b   Ren, Shuxin ^b   Guo, Yang Dong ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b VIRGINIA STATE UNIVERSITY   (United States)

Author keywords

Abiotic stress; Genetic modification; Mechanism; Melatonin; Plants; Tolerance

Indexed keywords

MELATONIN; PHYTOHORMONE; PLANT PROTEIN;

DROUGHT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGICAL STRESS; PLANT PHYSIOLOGY; TRANSGENIC PLANT;

DROUGHTS; GENE EXPRESSION REGULATION, PLANT; MELATONIN; PLANT GROWTH REGULATORS; PLANT PHYSIOLOGICAL PHENOMENA; PLANT PROTEINS; PLANTS, GENETICALLY MODIFIED; STRESS, PHYSIOLOGICAL;

EID: 84940640442     PISSN: 00220957     EISSN: 14602431     Source Type: Journal    
DOI: 10.1093/jxb/eru336     Document Type: Article

References (112)

1. Afreen F, Zobayed S, Kozai T. 2006. Melatonin in Glycyrrhiza uralensis: response of plant roots to spectral quality of light and UV-B radiation. Journal of Pineal Research 41, 108-115.
2. Allegra M, Reiter RJ, Tan DX, Gentile C, Tesoriere L, Livrea MA. 2003. The chemistry of melatonin's interaction with reactive species. Journal of Pineal Research 34, 1-10.
3. Arnao MB, Hernández-Ruiz J. 2007. Melatonin promotes adventitiousand lateral root regeneration in etiolated hypocotyls of Lupinus albus L. Journal of Pineal Research 42, 147-152.
4. Arnao MB, Hernández-Ruiz J. 2009a. Assessment of different sample processing procedures applied to the determination of melatonin in plants. Phytochemical Analysis 20, 14-18.
5. Arnao MB, Hernández-Ruiz J. 2009b. Chemical stress by different agents affects the melatonin content of barley roots. Journal of Pineal Research 46, 295-299.
6. Arnao MB, Hernández-Ruiz J. 2009c. Protective effect of melatonin against chlorophyll degradation during the senescence of barley leaves. Journal of Pineal Research 46, 58-63.
7. Arnao MB, Hernández-Ruiz J. 2006. The physiological function of melatonin in plants. Plant Signaling and Behavior 1, 89-95.
8. Arnao MB, Hernández-Ruiz J. 2013. Growth conditions determine different melatonin levels in Lupinus albus L. Journal of Pineal Research 55, 149-155.
9. Bajwa VS, Shukla MR, Sherif SM, Murch SJ, Saxena PK. 2014. Role of melatonin in alleviating cold stress in Arabidopsis thaliana. Journal of Pineal Research 56, 238-245.
10. Baxter A, Mittler R, Suzuki N. 2014. ROS as key players in plant stress signalling. Journal of Experimental Botany 65, 1229-1240.
11. Bose J, Rodrigo-Moreno A, Shabala S. 2014. ROS homeostasis in halophytes in the context of salinity stress tolerance. Journal of Experimental Botany 65, 1241-1257.
12. Bouchereau A, Aziz A, Larher F, Martin-Tanguy J. 1999. Polyamines and environmental challenges: recent development. Plant Science 140, 103-125.
13. Byeon Y, Back KW. 2013. Melatonin synthesis in rice seedlings in vivo is enhanced at high temperatures and under dark conditions due to increased serotonin N-acetyltransferase and N-acetylserotonin methyltransferase activities. Journal of Pineal Research 56, 189-195.
14. Byeon Y, Back KW. 2014. An increase in melatonin in transgenic rice causes pleiotropic phenotypes, including enhanced seedling growth, delayed flowering, and low grain yield. Journal of Pineal Research 56, 380-414.
15. Byeon Y, Lee HY, Lee K, Park S, Back KW. 2014a. Cellular localization and kinetics of the rice melatonin biosynthetic enzymes SNAT and ASMT. Journal of Pineal Research 56, 107-114.
16. Byeon Y, Park S, Kim YS, Back KW. 2013. Microarray analysis of genes differentially expressed in melatonin-rich transgenic rice expressing a sheep serotonin N-acetyltransferase. Journal of Pineal Research 55, 357-363.
17. Byeon Y, Park S, Kim YS, Park DH, Lee S, Back KW. 2012. Lightregulated melatonin biosynthesis in rice during the senescence process in detached leaves. Journal of Pineal Research 53, 107-111.
18. Byeon Y, Park S, Lee HY, Kim YS, Back KW. 2014b. Elevated production of melatonin in transgenic rice seeds expressing rice tryptophan decarboxylase. Journal of Pineal Research 56, 275-282.
19. Chen GF, Huo YS, Tan DX, Liang Z, Zhang WB, Zhang YK. 2003. Melatonin in Chinese medicinal herbs. Life Sciences 73, 19-26.
20. Chen Q, Qi WB, Reiter RJ, Wei W, Wang BM. 2009. Exogenously applied melatonin stimulates root growth and raises endogenous indoleacetic acid in roots of etiolated seedlings of Brassica juncea. Journal of Plant Physiology 166, 324-328.
21. Cho MH, No HK, Prinyawiwatkul W. 2008. Chitosan treatments affect growth and selected quality of sunflower sprouts. Journal of Food Science 73, 70-77.
22. Cipolla-Neto J, Amaral FG, Afeche SC, Tan DX, Reiter RJ. 2014. Melatonin, energy metabolism, and obesity: a review. Journal of Pineal Research 56, 371-381.
23. De luca V, Marineau C, Brisson N. 1989. Molecular-cloning and analysis of cDNA-encoding a plant tryptophan decarboxylase-comparison with animal dopa decarboxylases. Proceedings of the National Academy of Sciences, USA 86, 2582-2586.
24. Di Fiore S, Li QR, Leech MJ, Schuster F, Emans N, Fischer R, Schillberg S. 2002. Targeting tryptophan decarboxylase to selected subcellular compartments of tobacco plants affects enzyme stability and in vivo function and leads to a lesion-mimic phenotype. Plant Physiology 129, 1160-1169.
25. Dubbels R, Reiter RJ, Klenke E, Goebel A, Schnakenberg E, Ehlers C, Schiwara HW, Schloot W. 1995. Melatonin in edible plants identified by radioimmunoassay and by high-performance liquid chromatographymass spectrometry. Journal of Pineal Research 18, 28-31.
26. Flora SJS, Shrivastava R, Mittal M. 2013. Chemistry and pharmacological properties of some natural and synthetic antioxidants for heavy metal toxicity. Current Medicinal Chemistry 20, 4540-4574.
27. Foyer C, LopezDelgado H, Dat J, Scott I. 1997. Hydrogen peroxideand glutathione-associated mechanisms of acclimatory stress tolerance and signalling. Physiologia Plantarum 100, 241-254.
28. Foyer C, Noctor G. 2005. Oxidant and antioxidant signalling in plants: a re-evaluation of the concept of oxidative stress in a physiological context. Plant, Cell and Environment 28, 1056-1071.
29. Fujiwara T, Maisonneuve S, Isshiki M, Mizutani M, Chen L, Wong HL, Kawasaki T, Shimamoto K. 2010. Sekiguchi lesion gene encodes a cytochrome P450 monooxygenase that catalyzes conversion of tryptamine to serotonin in rice. Journal of Biological Chemistry 285, 11308-11313.
30. Hall J. 2002. Cellular mechanisms for heavy metal detoxification and tolerance. Journal of Experimental Botany 53, 1-11.
31. Hernández-Ruiz J, Arnao MB. 2008. Distribution of melatonin in different zones of lupin and barley plants at different ages in the presence and absence of light. Journal of Agricultural and Food Chemistry 56, 10567-10573.
32. Hernández-Ruiz J, Arnao MB. 2008. Melatonin stimulates the expansion of etiolated lupin cotyledons. Plant Growth Regulation 55, 29-34.
33. Hernández-Ruiz J, Cano A, Arnao MB. 2004. Melatonin: a growthstimulating compound present in lupin tissues. Planta 220, 140-144.
34. Hernández-Ruiz J, Cano A, Arnao MB. 2005. Melatonin acts as a growth-stimulating compound in some monocot species. Journal of Pineal Research 39, 137-142.
35. Hung S, Wang C, Ivanov S, Alexieva V, Yu C. 2007. Repetition of hydrogen peroxide treatment induces a chilling tolerance comparable to cold acclimation in mung bean. Journal of the American Society for Horticultural Science 132, 770-776.
36. Jayaweera M, Kasturiarachchi J. 2004. Removal of nitrogen and phosphorus from industrial wastewaters by phytoremediation using water hyacinth (Eichhornia crassipes (Mart.) Solms). Water Science and Technology 50, 217-225.
37. Kang K, Kim YS, Park S, Back KW. 2009. Senescence-induced serotonin biosynthesis and its role in delaying senescence in rice leaves. Plant Physiology 150, 1380-1393.
38. Kang K, Kong K, Park S, Natsagdorj U, Kim Y, Back K. 2011. Molecular cloning of a plant N-acetylserotonin methyltransferase and its expression characteristics in rice. Journal of Pineal Research 50, 304-309.
39. Kang K, Lee K, Park S, Byeon Y, Back KW. 2013. Molecular cloning of rice serotonin N-acetyltransferase, the penultimate gene in plant melatonin biosynthesis. Journal of Pineal Research 55, 7-13.
40. Kang K, Lee K, Park S, Kim YS, Back KW. 2010. Enhanced production of melatonin by ectopic overexpression of human serotonin N-acetyltransferase plays a role in cold resistance in transgenic rice seedlings. Journal of Pineal Research 49, 176-182.
41. Kang S, Kang K, Lee K, Back KW. 2007. Characterization of tryptamine 5-hydroxylase and serotonin synthesis in rice plants. Plant Cell Reports 26, 2009-2015.
42. Kang S, Kang K, Lee K, Back KW. 2008. Characterization of rice tryptophan decarboxylases and their direct involvement in serotonin biosynthesis in transgenic rice. Planta 227, 263-272.
43. Kanjanaphachoat P, Wei BY, Lo SF, Wang IW, Wang CS, Yu SM, Yen ML, Chiu SH, Lai CC, Chen L. 2012. Serotonin accumulation in transgenic rice by over-expressing tryptophan decarboxlyase results in a dark brown phenotype and stunted growth. Plant Molecular Biology 78, 525-543.
44. Kim T, Kim S, Han T, Lee J, Chang S. 2002. ABA and polyamines act independently in primary leaves of cold-stressed tomato (Lycopersicon esculentum). Physiologia Plantarum 115, 370-376.
45. Kolar J, Johnson C, Machackova I. 2003. Exogenously applied melatonin (N-acetyl-5-methoxytryptamine) affects flowering of the shortday plant Chenopodium rubrum. Physiologia Plantarum 118, 605-612.
46. Koyama FC, Carvalho TLG, Alves E, da Silva HB, de Azevedo MF, Hemerly AS, Garcia CRS. 2013. The structurally related auxin and melatonin tryptophan-derivatives and their roles in Arabidopsis thaliana and in the human malaria parasite Plasmodium falciparum. Journal of Eukaryotic Microbiology 60, 646-651.
47. Kratsch H, Wise R. 2000. The ultrastructure of chilling stress. Plant, Cell and Environment 23, 337-350.
48. Lei X, Zhu R, Zhang G, Dai Y. 2004. Attenuation of cold-induced apoptosis by exogenous melatonin in carrot suspension cells: the possible involvement of polyamines. Journal of Pineal Research 36, 126-131.
49. Lerner AB, Case J, Takahashi Y, Lee T, Mori W. 1958. Isolation of melatonin, the pineal gland factor that lightens melanocytes. Journal of the American Chemical Society 80, 2587-2587.
50. Li C, Wang P, Wei Z, Liang D, Liu C, Yin L, Jia D, Fu M, Ma F. 2012. The mitigation effects of exogenous melatonin on salinity-induced stress in Malus hupehensis. Journal of Pineal Research 53, 298-306.
51. Limson J, Nyokong T, Daya S. 1998. The interaction of melatonin and its precursors with aluminium, cadmium, copper, iron, lead, and zinc: an adsorptive voltammetric study. Journal of Pineal Research 24, 15-21.
52. Manchester LC, Tan DX, Reiter RJ, Park W, Monis K, Qi W. 2000. High levels of melatonin in the seeds of edible plants-possible function in germ tissue protection. Life Sciences 67, 3023-3029.
53. Misbahuddin M, Fariduddin A. 2002. Water hyacinth removes arsenic from arsenic-contaminated drinking water. Archives of Environmental Health 57, 516-518.
54. Mittler R. 2002. Oxidative stress, antioxidants and stress tolerance. Trends in Plant Science 7, 405-410.
55. Moschou PN, Roubelakis-Angelakis KA. 2014. Polyamines and programmed cell death. Journal of Experimental Botany 65, 1285-1296.
56. Munavalli GR, Saler PS. 2009. Treatment of dairy wastewater by water hyacinth. Water Science and Technology 59, 713-722.
57. Murch SJ, Campbell SSB, Saxena PK. 2001. The role of serotonin and melatonin in plant morphogenesis: regulation of auxin-induced root organogenesis in in vitro-cultured explants of St. John's wort (Hypericum perforatum L.). In Vitro Cellular and Developmental Biology-Plant 37, 786-793.
58. Murch SJ, KrishnaRaj S, Saxena P. 2000. Tryptophan is a precursor for melatonin and serotonin biosynthesis in in vitro regenerated St. John's wort (Hypericum perforatum L. cv. Anthos) plants. Plant Cell Reports 19, 698-704.
59. Okazaki M, Higuchi K, Hanawa Y, Shiraiwa Y, Ezura H. 2009. Cloning and characterization of a Chlamydomonas reinhardtii cDNA arylalkylamine N-acetyltransferase and its use in the genetic engineering of melatonin content in the Micro-Tom tomato. Journal of Pineal Research 46, 373-382.
60. Paredes SD, Korkmaz A, Manchester LC, Tan DX, Reiter RJ. 2009. Phytomelatonin: a review. Journal of Experimental Botany 60, 57-69.
61. Park S, Back KW. 2012. Melatonin promotes seminal root elongation and root growth in transgenic rice after germination. Journal of Pineal Research 53, 385-389.
62. Park S, Byeon Y, Back KW. 2013a. Functional analyses of three ASMT gene family members in rice plants. Journal of Pineal Research 55, 409-415.
63. Park S, Kang K, Lee K, Choi D, Kim Y, Back K. 2009. Induction of serotonin biosynthesis is uncoupled from the coordinated induction of tryptophan biosynthesis in pepper fruits (Capsicum annuum) upon pathogen infection. Planta 230, 1197-1206.
64. Park S, Lee DE, Jang H, Byeon Y, Kim YS, Back K. 2013b. Melatoninrich transgenic rice plants exhibit resistance to herbicide-induced oxidative stress. Journal of Pineal Research 54, 258-263.
65. Parmar P, Limson J, Nyokong T, Daya S. 2002. Melatonin protects against copper-mediated free radical damage. Journal of Pineal Research 32, 237-242.
66. Passaia G, Queval G, Bai J, Margis-Pinheiro M, Foyer CH. 2014. The effects of redox controls mediated by glutathione peroxidases on root architecture in Arabidopsis thaliana. Journal of Experimental Botany 65, 1403-1413.
67. Pelagio-Flores R, Munoz-Parra E, Ortiz-Castro R, Lopez-Bucio J. 2012. Melatonin regulates Arabidopsis root system architecture likely acting independently of auxin signaling. Journal of Pineal Research 53, 279-288.
68. Posmyk M, Balabusta M, Wieczorek M, Sliwinska E, Janas K. 2009. Melatonin applied to cucumber (Cucumis sativus L.) seeds improves germination during chilling stress. Journal of Pineal Research 46, 214-223.
69. Posmyk MM, Janas KM. 2009. Melatonin in plants. Acta Physiologiae Plantarum 31, 1-11.
70. Posmyk MM, Kuran H, Marciniak K, Janas KM. 2008. Presowing seed treatment with melatonin protects red cabbage seedlings against toxic copper ion concentrations. Journal of Pineal Research 45, 24-31.
71. Prasad T, Anderson M, Martin B, Stewart C. 1994. Evidence for chilling-induced oxidative stress in maize seedlings and a regulatory role for hydrogen-peroxide. The Plant Cell 6, 65-74.
72. Reiter RJ, Tan D-X, Fuentes-Broto L. 2010. Melatonin: a multitasking molecule. Progress in Brain Research 181, 127-151.
73. Reppert S. 1997. Melatonin receptors: molecular biology of a new family of G protein-coupled receptors. Journal of Biological Rhythms 12, 528-531.
74. Riddle S, Tran H, Dewitt J, Andrews J. 2002. Field, laboratory, and X-ray absorption spectroscopic studies of mercury accumulation by water hyacinths. Environmental Science and Technology 36, 1965-1970.
75. Riga P, Medina S, Garcia-Flores LA, Gil-Izquierdo A. 2014. Melatonin content of pepper and tomato fruits: effects of cultivar and solar radiation. Food Chemistry 156, 347-352.
76. Rodriguez C, Mayo J, Sainz R, Antolin I, Herrera F, Martin V, Reiter RJ. 2004. Regulation of antioxidant enzymes: a significant role for melatonin. Journal of Pineal Research 36, 1-9.
77. Romero A, Ramos E, de Los Ríos C, Egea J, del Pino J, Reiter RJ. 2014. A review of metal-catalyzed molecular damage: protection by melatonin. Journal of Pineal Research 56, 343-370.
78. Sarropoulou VN, Dimassi-Theriou K, Therios I, Koukourikou-Petridou M. 2012a. Melatonin enhances root regeneration, photosynthetic pigments, biomass, total carbohydrates and proline content in the cherry rootstock PHL-C (Prunus avium×Prunus cerasus). Plant Physiology and Biochemistry 61, 162-168.
79. Sarropoulou VN, Therios IN, Dimassi-Theriou K. 2012b. Melatonin promotes adventitious root regeneration in in vitro shoot tip explants of the commercial sweet cherry rootstocks CAB-6P (Prunus cerasus L.), Gisela 6 (P. cerasus P. canescens), and MxM 60 (P. avium P. mahaleb). Journal of Pineal Research 52, 38-46.
80. Sarrou E, Therios I, Dimassi-Theriou K. 2014. Melatonin and other factors that promote rooting and sprouting of shoot cuttings in Punica granatum cv. Wonderful. Turkish Journal of Botany 38, 293-301.
81. Shida C, Castrucci A, Lamyfreund M. 1994. High melatonin solubility in aqueous-medium. Journal of Pineal Research 16, 198-201.
82. Simopoulos A, Tan DX, Manchester LC, Reiter RJ. 2005. Purslane: a plant source of omega-3 fatty acids and melatonin. Journal of Pineal Research 39, 331-332.
83. Singhal V, Rai J. 2003. Biogas production from water hyacinth and channel grass used for phytoremediation of industrial effluents. Bioresource Technology 86, 221-225.
84. Szafranska K, Glinska S, Janas KM. 2012. Changes in the nature of phenolic deposits after re-warming as a result of melatonin pre-sowing treatment of Vigna radiata seeds. Journal of Plant Physiology 169, 34-40.
85. Szafranska K, Glinska S, Janas KM. 2013. Ameliorative effect of melatonin on meristematic cells of chilled and re-warmed Vigna radiata roots. Biologia Plantarum 57, 91-96.
86. Tal O, Haim A, Harel O, Gerchman Y. 2011. Melatonin as an antioxidant and its semi-lunar rhythm in green macroalga Ulva sp. Journal of Experimental Botany 62, 1903-1910.
87. Tan DX, Hardeland R, Manchester LC, Rosales-Corral S, Coto-Montes A, Boga JA, Reiter RJ. 2012. Emergence of naturally occurring melatonin isomers and their proposed nomenclature. Journal of Pineal Research 53, 113-121.
88. Tan DX, Manchester LC, Di Mascio P, Martinez GR, Prado FM, Reiter RJ. 2007a. Novel rhythms of N-1-acetyl-N-2-formyl-5-methoxykynuramine and its precursor melatonin in water hyacinth: importance for phytoremediation. FASEB Journal 21, 1724-1729.
89. Tan DX, Manchester LC, Helton P, Reiter RJ. 2007b. Phytoremediative capacity of plants enriched with melatonin. Plant Signaling and Behavior 2, 514-516.
90. Tan DX, Manchester LC, Liu XY, Rosales-Corral SA, Acuna-Castroviejo D, Reiter RJ. 2013. Mitochondria and chloroplasts as the original sites of melatonin synthesis: a hypothesis related to melatonin's primary function and evolution in eukaryotes. Journal of Pineal Research 54, 127-138.
91. Tan DX, Manchester LC, Reiter RJ, Plummer B, Limson J, Weintraub S, Qi W. 2000. Melatonin directly scavenges hydrogen peroxide: a potentially new metabolic pathway of melatonin biotransformation. Free Radical Biology and Medicine 29, 1177-1185.
92. Tiryaki I, Keles H. 2012. Reversal of the inhibitory effect of light and high temperature on germination of Phacelia tanacetifolia seeds by melatonin. Journal of Pineal Research 52, 332-339.
93. Trivedy R, Pattanshetty S. 2002. Treatment of dairy waste by using water hyacinth. Water Science and Technology 45, 329-334.
94. Uchendu EE, Shukla MR, Reed BM, Saxena PK. 2013. Melatonin enhances the recovery of cryopreserved shoot tips of American elm (Ulmus americana L.). Journal of Pineal Research 55, 435-442.
95. van Tassel D, O'Neill S. 2001. Putative regulatory molecules in plants: evaluating melatonin. Journal of Pineal Research 31, 1-7.
96. Vicente Gomez FJ, Raba J, Cerutti S, Fernanda Silva M. 2012. Monitoring melatonin and its isomer in Vitis vinifera cv. Malbec by UHPLC-MS/MS from grape to bottle. Journal of Pineal Research 52, 349-355
97. Vitalini S, Gardana C, Simonetti P, Fico G, Iriti M. 2013. Melatonin, melatonin isomers and stilbenes in Italian traditional grape products and their antiradical capacity. Journal of Pineal Research 54, 322-333
98. von Gall C, Stehle J, Weaver D. 2002. Mammalian melatonin receptors: molecular biology and signal transduction. Cell and Tissue Research 309, 151-162.
99. Wang H, Li L, Zhao M, Chen YH, Zhang ZH, Zhang C, Ji YL, Meng XH, Xu DX. 2011. Melatonin alleviates lipopolysaccharide-induced placental cellular stress response in mice. Journal of Pineal Research 50, 418-426.
100. Wang L, Zhao Y, Reiter RJ, He C, Liu G, Lei Q, Zuo B, Zheng XD, Li Q, Kong J. 2014. Changes in melatonin levels in transgenic 'Micro-Tom' tomato overexpressing ovine AANAT and ovine HIOMT genes. Journal of Pineal Research 56, 134-142.
101. Wang P, Sun X, Chang C, Feng F, Liang D, Cheng L, Ma FW. 2013a. Delay in leaf senescence of Malus hupehensis by long-term melatonin application is associated with its regulation of metabolic status and protein degradation. Journal of Pineal Research 55, 424-434.
102. Wang P, Sun X, Li C, Wei Z, Liang D, Ma FW. 2013b. Long-term exogenous application of melatonin delays drought-induced leaf senescence in apple. Journal of Pineal Research 54, 292-302.
103. Wang P, Yin L, Liang D, Li C, Ma F, Yue Z. 2012. Delayed senescence of apple leaves by exogenous melatonin treatment: toward regulating the ascorbate-glutathione cycle. Journal of Pineal Research 53, 11-20.
104. Weeda S, Zhang N, Zhao X, Ndip G, Guo Y, Buck GA, Fu C, Ren SX. 2014. Arabidopsis transcriptome analysis reveals key roles of melatonin in plant defense systems. PLoS One 9, e93462-e93462.
105. Xia H, Ma X. 2006. Phytoremediation of ethion by water hyacinth (Eichhornia crassipes) from water. Bioresource Technology 97, 1050-1054.
106. Yilmaz C, Kocadagli T, Gokmen V. 2014. Formation of melatonin and its isomer during bread dough fermentation and effect of baking. Journal of Agricultural and Food Chemistry 62, 2900-2905.
107. Yin L, Wang P, Li M, et al. 2013. Exogenous melatonin improves Malus resistance to Marssonina apple blotch. Journal of Pineal Research 54, 426-434.
108. Zhang HX, Blumwald E. 2001. Transgenic salt-tolerant tomato plants accumulate salt in foliage but not in fruit. Nature Biotechnology 19, 765-768.
109. Zhang L, Jia J, Xu Y, Wang Y, Hao J, Li T. 2012. Production of transgenic Nicotiana sylvestris plants expressing melatonin synthetase genes and their effect on UV-B-induced DNA damage. In Vitro Cellular and Developmental Biology-Plant 48, 275-282.
110. Zhang N, Zhang HJ, Zhao B, et al. 2014. The RNA-seq approach to discriminate gene expression profiles in response to melatonin on cucumber lateral root formation. Journal of Pineal Research 56, 39-50.
111. Zhang N, Zhao B, Zhang HJ, Weeda S, Yang C, Yang ZC, Ren SX, Guo YD. 2013. Melatonin promotes water-stress tolerance, lateral root formation, and seed germination in cucumber (Cucumis sativus L.). Journal of Pineal Research 54, 15-23.
112. Zhao Y, Qi L, Wang W, Saxena P, Liu C. 2011. Melatonin improves the survival of cryopreserved callus of Rhodiola crenulata. Journal of Pineal Research 50, 83-88.