메뉴 건너뛰기




Volumn 47, Issue 9, 2015, Pages 1061-1066

Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma

(38)  Jiang, Lu a   Gu, Zhao Hui a   Yan, Zi Xun a   Zhao, Xia a   Xie, Yin Yin a   Zhang, Zi Guan a   Pan, Chun Ming a   Hu, Yuan b   Cai, Chang Ping b   Dong, Ying c   Huang, Jin Yan a   Wang, Li a   Shen, Yang a   Meng, Guoyu a   Zhou, Jian Feng d   Hu, Jian Da e   Wang, Jin Fen f   Liu, Yuan Hua g   Yang, Lin Hua h   Zhang, Feng i   more..


Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; RNA; STAT PROTEIN; DDX3X PROTEIN, HUMAN; DEAD BOX PROTEIN;

EID: 84940585535     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3358     Document Type: Article
Times cited : (317)

References (52)
  • 1
    • 84882382389 scopus 로고    scopus 로고
    • How i treat NK/T-cell lymphomas
    • Tse, E. & Kwong, Y.L. How I treat NK/T-cell lymphomas. Blood 121, 4997-5005 (2013).
    • (2013) Blood , vol.121 , pp. 4997-5005
    • Tse, E.1    Kwong, Y.L.2
  • 2
    • 20044373438 scopus 로고    scopus 로고
    • Clinicopathologic features and treatment outcome of mature T-cell and natural killer-cell lymphomas diagnosed according to the World Health Organization classifcation scheme: A single center experience of 10 years
    • Au, W.Y. et al. Clinicopathologic features and treatment outcome of mature T-cell and natural killer-cell lymphomas diagnosed according to the World Health Organization classifcation scheme: a single center experience of 10 years. Ann. Oncol. 16, 206-214 (2005).
    • (2005) Ann. Oncol. , vol.16 , pp. 206-214
    • Au, W.Y.1
  • 3
    • 84892881790 scopus 로고    scopus 로고
    • Pathogenesis and treatment of extranodal natural killer/T-cell lymphoma
    • Suzuki, R. Pathogenesis and treatment of extranodal natural killer/T-cell lymphoma. Semin. Hematol. 51, 42-51 (2014).
    • (2014) Semin. Hematol. , vol.51 , pp. 42-51
    • Suzuki, R.1
  • 4
    • 77953227669 scopus 로고    scopus 로고
    • Prognostic factors for mature natural killer (NK) cell neoplasms: Aggressive NK cell leukemia and extranodal NK cell lymphoma, nasal type
    • Suzuki, R. et al. Prognostic factors for mature natural killer (NK) cell neoplasms: aggressive NK cell leukemia and extranodal NK cell lymphoma, nasal type. Ann. Oncol. 21, 1032-1040 (2010).
    • (2010) Ann. Oncol. , vol.21 , pp. 1032-1040
    • Suzuki, R.1
  • 5
    • 0347597762 scopus 로고    scopus 로고
    • Primary nasal natural killer cell lymphoma: Long-term treatment outcome and relationship with the International Prognostic Index
    • Chim, C.S. et al. Primary nasal natural killer cell lymphoma: long-term treatment outcome and relationship with the International Prognostic Index. Blood 103, 216-221 (2004).
    • (2004) Blood , vol.103 , pp. 216-221
    • Chim, C.S.1
  • 6
    • 84867810745 scopus 로고    scopus 로고
    • SMILE for natural killer/T-cell lymphoma: Analysis of safety and effcacy from the Asia Lymphoma Study Group
    • Kwong, Y.L. et al. SMILE for natural killer/T-cell lymphoma: analysis of safety and effcacy from the Asia Lymphoma Study Group. Blood 120, 2973-2980 (2012).
    • (2012) Blood , vol.120 , pp. 2973-2980
    • Kwong, Y.L.1
  • 7
    • 33644843494 scopus 로고    scopus 로고
    • Extranodal natural killer T-cell lymphoma, nasal-type: A prognostic model from a retrospective multicenter study
    • Lee, J. et al. Extranodal natural killer T-cell lymphoma, nasal-type: a prognostic model from a retrospective multicenter study. J. Clin. Oncol. 24, 612-618 (2006).
    • (2006) J. Clin. Oncol. , vol.24 , pp. 612-618
    • Lee, J.1
  • 8
    • 65449159015 scopus 로고    scopus 로고
    • Clinical differences between nasal and extranasal natural killer/T-cell lymphoma: A study of 136 cases from the International Peripheral T-Cell Lymphoma Project
    • Au, W.Y. et al. Clinical differences between nasal and extranasal natural killer/T-cell lymphoma: a study of 136 cases from the International Peripheral T-Cell Lymphoma Project. Blood 113, 3931-3937 (2009).
    • (2009) Blood , vol.113 , pp. 3931-3937
    • Au, W.Y.1
  • 9
    • 0035180449 scopus 로고    scopus 로고
    • P53 mutations in nasal natural killer/T-cell lymphoma from Mexico: Association with large cell morphology and advanced disease
    • Quintanilla-Martinez, L. et al. p53 mutations in nasal natural killer/T-cell lymphoma from Mexico: association with large cell morphology and advanced disease. Am. J. Pathol. 159, 2095-2105 (2001).
    • (2001) Am. J. Pathol. , vol.159 , pp. 2095-2105
    • Quintanilla-Martinez, L.1
  • 10
    • 84880639904 scopus 로고    scopus 로고
    • P63 and p53 expression in extranodal NK/T cell lymphoma, nasal type
    • Ye, Z. et al. p63 and p53 expression in extranodal NK/T cell lymphoma, nasal type. J. Clin. Pathol. 66, 676-680 (2013).
    • (2013) J. Clin. Pathol. , vol.66 , pp. 676-680
    • Ye, Z.1
  • 11
    • 1642539989 scopus 로고    scopus 로고
    • P53, N- and K-Ras, and β-catenin gene mutations and prognostic factors in nasal NK/T-cell lymphoma from Hokkaido, Japan
    • Takahara, M., Kishibe, K., Bandoh, N., Nonaka, S. & Harabuchi, Y. P53, N- and K-Ras, and β-catenin gene mutations and prognostic factors in nasal NK/T-cell lymphoma from Hokkaido, Japan. Hum. Pathol. 35, 86-95 (2004).
    • (2004) Hum. Pathol. , vol.35 , pp. 86-95
    • Takahara, M.1    Kishibe, K.2    Bandoh, N.3    Nonaka, S.4    Harabuchi, Y.5
  • 12
    • 53549130011 scopus 로고    scopus 로고
    • Immunohistochemical expression and clinical signifcance of P-glycoprotein in previously untreated extranodal NK/T-cell lymphoma, nasal type
    • Wang, B. et al. Immunohistochemical expression and clinical signifcance of P-glycoprotein in previously untreated extranodal NK/T-cell lymphoma, nasal type. Am. J. Hematol. 83, 795-799 (2008).
    • (2008) Am. J. Hematol. , vol.83 , pp. 795-799
    • Wang, B.1
  • 13
    • 77949535492 scopus 로고    scopus 로고
    • Gene expression profling identifes emerging oncogenic pathways operating in extranodal NK/T-cell lymphoma, nasal type
    • Huang, Y. et al. Gene expression profling identifes emerging oncogenic pathways operating in extranodal NK/T-cell lymphoma, nasal type. Blood 115, 1226-1237 (2010).
    • (2010) Blood , vol.115 , pp. 1226-1237
    • Huang, Y.1
  • 14
    • 67349138549 scopus 로고    scopus 로고
    • Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies
    • Iqbal, J. et al. Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies. Leukemia 23, 1139-1151 (2009).
    • (2009) Leukemia , vol.23 , pp. 1139-1151
    • Iqbal, J.1
  • 15
    • 80053121023 scopus 로고    scopus 로고
    • Identifcation of FOXO3 and PRDM1 as tumor-suppressor gene candidates in NK-cell neoplasms by genomic and functional analyses
    • Karube, K. et al. Identifcation of FOXO3 and PRDM1 as tumor-suppressor gene candidates in NK-cell neoplasms by genomic and functional analyses. Blood 118, 3195-3204 (2011).
    • (2011) Blood , vol.118 , pp. 3195-3204
    • Karube, K.1
  • 17
    • 80855128777 scopus 로고    scopus 로고
    • Dysregulated microRNAs affect pathways and targets of biologic relevance in nasal-type natural killer/T-cell lymphoma
    • Ng, S.B. et al. Dysregulated microRNAs affect pathways and targets of biologic relevance in nasal-type natural killer/T-cell lymphoma. Blood 118, 4919-4929 (2011).
    • (2011) Blood , vol.118 , pp. 4919-4929
    • Ng, S.B.1
  • 18
    • 79551696483 scopus 로고    scopus 로고
    • Activated oncogenic pathways and therapeutic targets in extranodal nasal-type NK/T cell lymphoma revealed by gene expression profling
    • Ng, S.B. et al. Activated oncogenic pathways and therapeutic targets in extranodal nasal-type NK/T cell lymphoma revealed by gene expression profling. J. Pathol. 223, 496-510 (2011).
    • (2011) J. Pathol. , vol.223 , pp. 496-510
    • Ng, S.B.1
  • 19
    • 84866314162 scopus 로고    scopus 로고
    • Janus kinase 3-activating mutations identifed in natural killer/T-cell lymphoma
    • Koo, G.C. et al. Janus kinase 3-activating mutations identifed in natural killer/T-cell lymphoma. Cancer Discov. 2, 591-597 (2012).
    • (2012) Cancer Discov. , vol.2 , pp. 591-597
    • Koo, G.C.1
  • 20
    • 0037959986 scopus 로고    scopus 로고
    • Analysis of p53, K-ras, c-kit, and beta-catenin gene mutations in sinonasal NK/T cell lymphoma in northeast district of China
    • Hoshida, Y. et al. Analysis of p53, K-ras, c-kit, and beta-catenin gene mutations in sinonasal NK/T cell lymphoma in northeast district of China. Cancer Sci. 94, 297-301 (2003).
    • (2003) Cancer Sci. , vol.94 , pp. 297-301
    • Hoshida, Y.1
  • 21
    • 84923076524 scopus 로고    scopus 로고
    • Activating mutations of STAT5B and STAT3 in lymphomas derived from gammadelta-T or NK cells
    • Küçük, C. et al. Activating mutations of STAT5B and STAT3 in lymphomas derived from gammadelta-T or NK cells. Nat. Commun. 6, 6025 (2015).
    • (2015) Nat. Commun. , vol.6 , pp. 6025
    • Küçük, C.1
  • 22
    • 84893761035 scopus 로고    scopus 로고
    • JAK3 deregulation by activating mutations confers invasive growth advantage in extranodal nasal-type natural killer cell lymphoma
    • Bouchekioua, A. et al. JAK3 deregulation by activating mutations confers invasive growth advantage in extranodal nasal-type natural killer cell lymphoma. Leukemia 28, 338-348 (2014).
    • (2014) Leukemia , vol.28 , pp. 338-348
    • Bouchekioua, A.1
  • 23
    • 84903815486 scopus 로고    scopus 로고
    • Rare occurrence of JAK3 mutations in natural killer cell neoplasms in Japan
    • Kimura, H. et al. Rare occurrence of JAK3 mutations in natural killer cell neoplasms in Japan. Leuk. Lymphoma 55, 962-963 (2014).
    • (2014) Leuk. Lymphoma , vol.55 , pp. 962-963
    • Kimura, H.1
  • 24
    • 84903168001 scopus 로고    scopus 로고
    • Activated janus kinase 3 expression not by activating mutations identifed in natural killer/T-cell lymphoma
    • Guo, Y. et al. Activated janus kinase 3 expression not by activating mutations identifed in natural killer/T-cell lymphoma. Pathol. Int. 64, 263-266 (2014).
    • (2014) Pathol. Int. , vol.64 , pp. 263-266
    • Guo, Y.1
  • 25
    • 0032733015 scopus 로고    scopus 로고
    • Comparative genomic hybridization analysis of natural killer cell lymphoma/leukemia: Recognition of consistent patterns of genetic alterations
    • Siu, L.L., Wong, K.-F., Chan, J.K. & Kwong, Y.-L. Comparative genomic hybridization analysis of natural killer cell lymphoma/leukemia: recognition of consistent patterns of genetic alterations. Am. J. Pathol. 155, 1419-1425 (1999).
    • (1999) Am. J. Pathol. , vol.155 , pp. 1419-1425
    • Siu, L.L.1    Wong, K.-F.2    Chan, J.K.3    Kwong, Y.-L.4
  • 26
    • 84867051939 scopus 로고    scopus 로고
    • Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
    • Schmitz, R. et al. Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics. Nature 490, 116-120 (2012).
    • (2012) Nature , vol.490 , pp. 116-120
    • Schmitz, R.1
  • 27
    • 84927638969 scopus 로고    scopus 로고
    • Identifcation of recurrent truncated DDX3X mutations in chronic lymphocytic leukaemia
    • Ojha, J. et al. Identifcation of recurrent truncated DDX3X mutations in chronic lymphocytic leukaemia. Br. J. Haematol. 169, 445-448 (2015).
    • (2015) Br. J. Haematol. , vol.169 , pp. 445-448
    • Ojha, J.1
  • 28
    • 84897091264 scopus 로고    scopus 로고
    • DDX3 loss by p53 inactivation promotes tumor malignancy via the MDM2/Slug/E-cadherin pathway and poor patient outcome in non-small-cell lung cancer
    • Wu, D.W. et al. DDX3 loss by p53 inactivation promotes tumor malignancy via the MDM2/Slug/E-cadherin pathway and poor patient outcome in non-small-cell lung cancer. Oncogene 33, 1515-1526 (2013).
    • (2013) Oncogene , vol.33 , pp. 1515-1526
    • Wu, D.W.1
  • 29
    • 79953305455 scopus 로고    scopus 로고
    • Reduced p21(WAF1/CIP1) via alteration of p53-DDX3 pathway is associated with poor relapse-free survival in early-stage human papillomavirus-associated lung cancer
    • Wu, D.W. et al. Reduced p21(WAF1/CIP1) via alteration of p53-DDX3 pathway is associated with poor relapse-free survival in early-stage human papillomavirus-associated lung cancer. Clin. Cancer Res. 17, 1895-1905 (2011).
    • (2011) Clin. Cancer Res. , vol.17 , pp. 1895-1905
    • Wu, D.W.1
  • 30
    • 84864419974 scopus 로고    scopus 로고
    • Dissecting the genomic complexity underlying medulloblastoma
    • Jones, D.T. et al. Dissecting the genomic complexity underlying medulloblastoma. Nature 488, 100-105 (2012).
    • (2012) Nature , vol.488 , pp. 100-105
    • Jones, D.T.1
  • 31
    • 84864492215 scopus 로고    scopus 로고
    • Medulloblastoma exome sequencing uncovers subtype-specifc somatic mutations
    • Pugh, T.J. et al. Medulloblastoma exome sequencing uncovers subtype-specifc somatic mutations. Nature 488, 106-110 (2012).
    • (2012) Nature , vol.488 , pp. 106-110
    • Pugh, T.J.1
  • 32
    • 84864444165 scopus 로고    scopus 로고
    • Novel mutations target distinct subgroups of medulloblastoma
    • Robinson, G. et al. Novel mutations target distinct subgroups of medulloblastoma. Nature 488, 43-48 (2012).
    • (2012) Nature , vol.488 , pp. 43-48
    • Robinson, G.1
  • 33
    • 33646017369 scopus 로고    scopus 로고
    • Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa
    • Sengoku, T., Nureki, O., Nakamura, A., Kobayashi, S. & Yokoyama, S. Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa. Cell 125, 287-300 (2006).
    • (2006) Cell , vol.125 , pp. 287-300
    • Sengoku, T.1    Nureki, O.2    Nakamura, A.3    Kobayashi, S.4    Yokoyama, S.5
  • 34
    • 84901424596 scopus 로고    scopus 로고
    • RNA binding protein-mediated post-transcriptional gene regulation in medulloblastoma
    • Bish, R. & Vogel, C. RNA binding protein-mediated post-transcriptional gene regulation in medulloblastoma. Mol. Cells 37, 357-364 (2014).
    • (2014) Mol. Cells , vol.37 , pp. 357-364
    • Bish, R.1    Vogel, C.2
  • 35
    • 4944266319 scopus 로고    scopus 로고
    • Epstein-Barr virus: 40 years on
    • Young, L.S. & Rickinson, A.B. Epstein-Barr virus: 40 years on. Nat. Rev. Cancer 4, 757-768 (2004).
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 757-768
    • Young, L.S.1    Rickinson, A.B.2
  • 36
    • 84879132779 scopus 로고    scopus 로고
    • The role of the DEAD-box RNA helicase DDX3 in mRNA metabolism. Wiley
    • Soto-Rifo, R. & Ohlmann, T. The role of the DEAD-box RNA helicase DDX3 in mRNA metabolism. Wiley. Interdiscip. Rev. RNA 4, 369-385 (2013).
    • (2013) Interdiscip. Rev. RNA , vol.4 , pp. 369-385
    • Soto-Rifo, R.1    Ohlmann, T.2
  • 37
    • 84927621119 scopus 로고    scopus 로고
    • Global promoter methylation analysis reveals novel candidate tumor suppressor genes in natural killer cell lymphoma
    • Küçük, C. et al. Global promoter methylation analysis reveals novel candidate tumor suppressor genes in natural killer cell lymphoma. Clin. Cancer Res. 21, 1699-1711 (2015).
    • (2015) Clin. Cancer Res. , vol.21 , pp. 1699-1711
    • Küçük, C.1
  • 38
    • 77951794067 scopus 로고    scopus 로고
    • Global survey of escape from X inactivation by RNA-sequencing in mouse
    • Yang, F. , Babak, T., Shendure, J. & Disteche, C.M. Global survey of escape from X inactivation by RNA-sequencing in mouse. Genome Res. 20, 614-622 (2010).
    • (2010) Genome Res. , vol.20 , pp. 614-622
    • Yang, F.1    Babak, T.2    Shendure, J.3    Disteche, C.M.4
  • 39
    • 67649884743 scopus 로고    scopus 로고
    • Fast and accurate short read alignment with Burrows-Wheeler transform
    • Li, H. & Durbin, R. Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 25, 1754-1760 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 1754-1760
    • Li, H.1    Durbin, R.2
  • 40
    • 68549104404 scopus 로고    scopus 로고
    • The Sequence Alignment/Map format and SAMtools
    • Li, H. et al. The Sequence Alignment/Map format and SAMtools. Bioinformatics 25, 2078-2079 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 2078-2079
    • Li, H.1
  • 41
    • 79955483667 scopus 로고    scopus 로고
    • A framework for variation discovery and genotyping using next-generation DNA sequencing data
    • DePristo, M.A. et al. A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nat. Genet. 43, 491-498 (2011).
    • (2011) Nat. Genet. , vol.43 , pp. 491-498
    • DePristo, M.A.1
  • 42
    • 84895809383 scopus 로고    scopus 로고
    • Somatic RHOA mutation in angioimmunoblastic T cell lymphoma
    • Sakata-Yanagimoto, M. et al. Somatic RHOA mutation in angioimmunoblastic T cell lymphoma. Nat. Genet. 46, 171-175 (2014).
    • (2014) Nat. Genet. , vol.46 , pp. 171-175
    • Sakata-Yanagimoto, M.1
  • 43
    • 68149165614 scopus 로고    scopus 로고
    • Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm
    • Kumar, P. , Henikoff, S. & Ng, P.C. Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. Nat. Protoc. 4, 1073-1081 (2009).
    • (2009) Nat. Protoc. , vol.4 , pp. 1073-1081
    • Kumar, P.1    Henikoff, S.2    Ng, P.C.3
  • 44
    • 77951640946 scopus 로고    scopus 로고
    • A method and server for predicting damaging missense mutations
    • Adzhubei, I.A. et al. A method and server for predicting damaging missense mutations. Nat. Methods 7, 248-249 (2010).
    • (2010) Nat. Methods , vol.7 , pp. 248-249
    • Adzhubei, I.A.1
  • 45
    • 84867301515 scopus 로고    scopus 로고
    • Predicting the functional effect of amino acid substitutions and indels
    • Choi, Y., Sims, G.E., Murphy, S., Miller, J.R. & Chan, A.P. Predicting the functional effect of amino acid substitutions and indels. PLoS ONE 7, e46688 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e46688
    • Choi, Y.1    Sims, G.E.2    Murphy, S.3    Miller, J.R.4    Chan, A.P.5
  • 46
    • 77956690576 scopus 로고    scopus 로고
    • A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping data
    • Yau, C. et al. A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping data. Genome Biol. 11, R92 (2010).
    • (2010) Genome Biol. , vol.11 , pp. R92
    • Yau, C.1
  • 47
    • 35948984173 scopus 로고    scopus 로고
    • PennCNV: An integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data
    • Wang, K. et al. PennCNV: an integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data. Genome Res. 17, 1665-1674 (2007).
    • (2007) Genome Res. , vol.17 , pp. 1665-1674
    • Wang, K.1
  • 48
    • 84874025843 scopus 로고    scopus 로고
    • Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
    • Cibulskis, K. et al. Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples. Nat. Biotechnol. 31, 213-219 (2013).
    • (2013) Nat. Biotechnol. , vol.31 , pp. 213-219
    • Cibulskis, K.1
  • 49
    • 9144265458 scopus 로고    scopus 로고
    • Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 Concerted Action BMH4-CT98-3936
    • van Dongen, J.J. et al. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia 17, 2257-2317 (2003).
    • (2003) Leukemia , vol.17 , pp. 2257-2317
    • Van Dongen, J.J.1
  • 50
    • 79955941981 scopus 로고    scopus 로고
    • A motif unique to the human DEAD-box protein DDX3 is important for nucleic acid binding, ATP hydrolysis, RNA/DNA unwinding and HIV-1 replication
    • Garbelli, A., Beermann, S., Di Cicco, G., Dietrich, U. & Maga, G. A motif unique to the human DEAD-box protein DDX3 is important for nucleic acid binding, ATP hydrolysis, RNA/DNA unwinding and HIV-1 replication. PLoS ONE 6, e19810 (2011).
    • (2011) PLoS ONE , vol.6 , pp. e19810
    • Garbelli, A.1    Beermann, S.2    Di Cicco, G.3    Dietrich, U.4    Maga, G.5
  • 51
    • 0142121516 scopus 로고    scopus 로고
    • Exploration, normalization, and summaries of high density oligonucleotide array probe level data
    • Irizarry, R.A. et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4, 249-264 (2003).
    • (2003) Biostatistics , vol.4 , pp. 249-264
    • Irizarry, R.A.1
  • 52
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profles
    • Subramanian, A. et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profles. Proc. Natl. Acad. Sci. USA 102, 15545-15550 (2005).
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.