Pharmacokinetics, in-situ absorption and protein binding studies of a new neuroleptic agent centbutindole in rats

European Journal of Pharmaceutical Sciences

Volumn 19, Issue 2-3, 2003, Pages 105-113

  Issar, Manish ^a   Singh, Shio K ^a   Mishra, Bhrameshwar ^b   Gupta, Ram C ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b BANARAS HINDU UNIVERSITY   (India)

Author keywords

Absorption; Centbutindole; Neuroleptic; Pharmacokinetics; Protein binding

Indexed keywords

ABSORPTION; DRUG DOSAGE; METABOLISM; PROTEINS; SOLUBILITY;

PROTEIN BINDING;

PHARMACOKINETICS;

CENTBUTINDOLE; DRUG METABOLITE; MACROGOL; NEUROLEPTIC AGENT; PYRAZINE DERIVATIVE;

ANIMAL; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BIOAVAILABILITY; BLOOD; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); DOSE TIME EFFECT RELATION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG EFFECT; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG SOLUBILITY; FIRST PASS EFFECT; GASTROINTESTINAL TRACT; IN VITRO STUDY; IN VIVO STUDY; INTESTINE ABSORPTION; MALE; MEASUREMENT; NONHUMAN; PARAMETER; PH; PHYSIOLOGY; PLASMA PROTEIN BINDING; PRIORITY JOURNAL; PROTEIN BINDING; RAT; RAT STRAIN; SYSTEMIC CIRCULATION; TECHNIQUE; ULTRAFILTRATION;

EID: 0038520847     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(03)00066-6     Document Type: Article

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