The emergence of sedentary behaviour physiology and its effects on the cardiometabolic profile in young and older adults

Age

Volumn 37, Issue 5, 2015, Pages

  Ryan, D J ^a   Stebbings, G K ^a   Onambele, G L ^a  

^a MANCHESTER METROPOLITAN UNIVERSITY   (United Kingdom)

Author keywords

Cardiometabolic; Older adults; Physical activity; Sedentary behaviour

Indexed keywords

ADIPONECTIN; GHRELIN; GLUCOSE; GLUCOSE TRANSPORTER 4; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LEPTIN; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NITRIC OXIDE; TRIACYLGLYCEROL;

ADULT; ARTICLE; ATHEROSCLEROSIS; BLOOD VESSEL COMPLIANCE; CARDIOMETABOLIC RISK; CARDIOVASCULAR DISEASE; CHOLESTEROL BLOOD LEVEL; FOAM CELL; GLYCEMIC CONTROL; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; MACROPHAGE; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATIVE STRESS; PHYSICAL ACTIVITY; SEDENTARY LIFESTYLE; VASCULAR RESISTANCE; YOUNG ADULT; AGED; AGING; MOTOR ACTIVITY; PATHOPHYSIOLOGY; PHYSIOLOGY; QUALITY OF LIFE;

ADULT; AGED; AGING; CARDIOVASCULAR DISEASES; HUMANS; MOTOR ACTIVITY; QUALITY OF LIFE; SEDENTARY LIFESTYLE; YOUNG ADULT;

EID: 84940473986     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-015-9832-7     Document Type: Article

References (81)

1. Abdul-Ghani MA, Tripathy D, DeFronzo RA (2006) Contributions of β-cell dysfunction and insulin resistance to the pathogenesis of impaired glucose tolerance and impaired fasting glucose. Diabetes Care 29:1130–1139
2. Ainsworth BE et al (2000) Compendium of physical activities: an update of activity codes and MET intensities. Med Sci Sports Exerc 32:S498–S504
3. Aronow WS, Ahn C (1996) Risk factors for new coronary events in a large cohort of very elderly patients with and without coronary artery disease. Am J Cardiol 77:864–866
4. Baigent C et al (2010) Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet 376:1670
5. Bailey DP, Locke CD (2014) Breaking up prolonged sitting with light-intensity walking improves postprandial glycemia, but breaking up sitting with standing does not Journal of Science and Medicine in Sport [online]
6. Bankoski A et al (2011) Sedentary activity associated with metabolic syndrome independent of physical activity. Diabetes Care 34:497–503
7. Bey L, Areiqat E, Sano A, Hamilton MT (2001) Reduced lipoprotein lipase activity in postural skeletal muscle during aging. J Appl Physiol 91:687–692
8. Bey L, Hamilton MT (2003) Suppression of skeletal muscle lipoprotein lipase activity during physical inactivity: a molecular reason to maintain daily low-intensity activity. J Physiol 551:673–682
9. Biensø RS et al. (2015) Effects of exercise training on regulation of skeletal muscle glucose metabolism in elderly men. J Gerontol Ser A Biol Sci Med Sci glv012
10. Björkerud B, Björkerud S (1996) Contrary effects of lightly and strongly oxidized LDL with potent promotion of growth versus apoptosis on arterial smooth muscle cells, macrophages, and fibroblasts Arteriosclerosis. Thrombosis Vasc Biol 16:416–424
11. Björnheden T, Babyi A, Bondjers G, Wiklund O (1996) Accumulation of lipoprotein fractions and subfractions in the arterial wall, determined in an in vitro perfusion system. Atherosclerosis 123:43–56
12. Blanc S, Normand S, Pachiaudi C, Duvareille M, Gharib C (2000a) Leptin responses to physical inactivity induced by simulated weightlessness. Am J Physiol Regul Integr Comparat Physiol 279:R891–R898
13. Blanc S, Normand S, Pachiaudi C, Fortrat J-O, Laville M, Gharib C (2000b) Fuel homeostasis during physical inactivity induced by bed rest. J Clin Endocrinol Metab 85:2223–2233
14. British Heart Foundation (2014) Cardiovascualr disease statistics 2014. London, England
15. Carson V, Wong SL, Winkler E, Healy GN, Colley RC, Tremblay MS (2014) Patterns of sedentary time and cardiometabolic risk among Canadian adults. Prev Med 65:23–27
16. Chau JY et al (2013) Daily sitting time and all-cause mortality: a meta-analysis. PLoS One 8:e80000
17. Clee SM et al (2000) Plasma and vessel wall lipoprotein lipase have different roles in atherosclerosis. J Lipid Res 41:521–531
18. Cominacini L et al (2000) Oxidized low density lipoprotein (ox-LDL) binding to ox-LDL receptor-1 in endothelial cells induces the activation of NF-κB through an increased production of intracellular reactive oxygen species. J Biol Chem 275:12633–12638
19. Cox JH, Cortright RN, Dohm GL, Houmard JA (1999) Effect of aging on response to exercise training in humans: skeletal muscle GLUT-4 and insulin sensitivity. J Appl Physiol 86:2019–2025
20. Craig R (2013) Health survey for England 2012. Leeds, England
21. Craig R, Mindell J, Hirani V (2009) Health Survey for England 2008. Volume 1: physical activity and fitness health survey for England 1:8–395
22. Cui Y, Blumenthal RS, Flaws JA, Whiteman MK, Langenberg P, Bachorik PS, Bush TL (2001) Non–high-density lipoprotein cholesterol level as a predictor of cardiovascular disease mortality. Arch Intern Med 161:1413–1419
23. Di Francesco V et al (2006) Unbalanced serum leptin and ghrelin dynamics prolong postprandial satiety and inhibit hunger in healthy elderly: another reason for the “anorexia of aging”. Am J Clin Nutr 83:1149–1152
24. Diabetes UK (2012) Diabetes in the UK 2012 key statistics on diabetes. http://www.diabetes.org.uk/diabetes-in-the-uk-2012. Accessed 16 Oct 2014
25. Dipietro L, Caspersen CJ, Ostfeld AM, Nadel ER (1993) A survey for assessing physical activity among older adults. Med Sci Sports Exerc 25:628–642
26. Dunstan DW et al (2012) Breaking up prolonged sitting reduces postprandial glucose and insulin responses. Diabetes Care 35:976–983
27. Dunstan DW, Salmon J, Healy GN, Shaw JE, Jolley D, Zimmet PZ, Owen N (2007) Association of television viewing with fasting and 2-h postchallenge plasma glucose levels in adults without diagnosed diabetes. Diabetes Care 30:516–522
28. Fatouros I et al (2005) Leptin and adiponectin responses in overweight inactive elderly following resistance training and detraining are intensity related. J Clin Endocrinol Metab 90:5970–5977
29. Förstermann U, Münzel T (2006) Endothelial nitric oxide synthase in vascular disease from marvel to menace. Circulation 113:1708–1714
30. Franzoni F et al (2005) Physical activity, plasma antioxidant capacity, and endothelium-dependent vasodilation in young and older men. Am J Hypertens 18:510–516
31. Freedson PS, Melanson E, Sirard J (1998) Calibration of the computer science and applications. Inc Acceleromet Med Sci Sports Exer 30:777–781
32. Gaster M, Poulsen P, Handberg A, Schrøder H, Beck-Nielsen H (2000) Direct evidence of fiber type-dependent GLUT-4 expression in human skeletal muscle American Journal of Physiology-Endocrinology And. Metabolism 278:E910–E916
33. Gennuso KP, Gangnon RE, Matthews CE, Thraen-Borowski KM, Colbert LH (2013) Sedentary behavior, physical activity, and markers of health in older adults. Med Sci Sports Exerc 45:1493–1500
34. Gong Z, Muzumdar RH (2012) Pancreatic function, type 2 diabetes, and metabolism in aging International. J Endocrinol 2012:320482
35. Gonzalez M, Lind L, Söderberg S (2013) Leptin and endothelial function in the elderly: the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study. Atherosclerosis 228:485–490
36. Hamilton M, Healy G, Dunstan D, Zderic T, Owen N (2008) Too little exercise and too much sitting: inactivity physiology and the need for new recommendations on sedentary behavior. Curr Cardiovasc Risk Rep 2:292–298
37. Hamilton MT, Etienne J, McClure WC, Pavey BS, Holloway AK (1998) Role of local contractile activity and muscle fiber type on LPL regulation during exercise. Am J Physiol Endocrinol Metab 275:E1016–E1022
38. Harvey JA, Chastin SF, Skelton DA (2013) Prevalence of sedentary behavior in older adults: a systematic review. Int J Environ Res Publ Health 10:6645–6661
39. Healy GN, Dunstan DW, Salmon J, Cerin E, Shaw JE, Zimmet PZ, Owen N (2007) Objectively measured light-intensity physical activity is independently associated with 2-h plasma glucose. Diabetes Care 30:1384–1389
40. Healy GN, Dunstan DW, Salmon J, Cerin E, Shaw JE, Zimmet PZ, Owen N (2008a) Breaks in sedentary time beneficial associations with metabolic risk. Diabetes Care 31:661–666
41. Healy GN, Dunstan DW, Salmon J, Shaw JE, Zimmet PZ, Owen N (2008b) Television time and continuous metabolic risk in physically active adults. Med Sci Sports Exerc 40:639–645
42. Hennig R, Lømo T (1985) Firing patterns of motor units in normal rats
43. Host HH, Hansen PA, Nolte LA, Chen MM, Holloszy JO (1998) Rapid reversal of adaptive increases in muscle GLUT-4 and glucose transport capacity after training cessation. J Appl Physiol 84:798–802
44. Houmard J et al (1995) Skeletal muscle GLUT4 protein concentration and aging in humans. Diabetes 44:555
45. Kazmi A, Sattar A, Hashim R, Khan SP, Younus M, Khan FA (2013) Serum Leptin values in the healthy obese and non-obese subjects of Rawalpindi. JPMA J Pakistan Med Assoc 63:245–248
46. Keaney JF Jr, Guo Y, Cunningham D, Shwaery GT, Xu A, Vita JA (1996) Vascular incorporation of alpha-tocopherol prevents endothelial dysfunction due to oxidized LDL by inhibiting protein kinase C stimulation. J Clin Investig 98:386–394
47. Kriska A (2000) Ethnic and cultural issues in assessing physical activity. Res Q Exerc Sport 71:S47–S53
48. Latouche C, Jowett JB, Carey AL, Bertovic DA, Owen N, Dunstan DW, Kingwell BA (2013) Effects of breaking up prolonged sitting on skeletal muscle gene expression. J Appl Physiol 114:453–460
49. Laufs U, Wassmann S, Czech T, Münzel T, Eisenhauer M, Böhm M, Nickenig G (2005) Physical inactivity increases oxidative stress, endothelial dysfunction, and atherosclerosis. Arterioscler Thromb Vasc Biol 25:809–814
50. Li Y, He P-P, Zhang D-W, Zheng X-L, Cayabyab FS, Yin W-D, Tang C-K (2014) Lipoprotein lipase: from gene to atherosclerosis. Atherosclerosis 237:597–608
51. Lund S, Holman G, Schmitz O, Pedersen O (1995) Contraction stimulates translocation of glucose transporter GLUT4 in skeletal muscle through a mechanism distinct from that of insulin. Proc Natl Acad Sci 92:5817–5821
52. Mansoubi M et al (2015) Energy expenditure during common sitting and standing tasks: examining the 1.5 MET definition of sedentary behaviour. BMC Public Health 15:516
53. Mead JR, Cryer A, Ramji DP (1999) Lipoprotein lipase, a key role in atherosclerosis? FEBS Lett 462:1–6
54. Mead JR, Ramji DP (2002) The pivotal role of lipoprotein lipase in atherosclerosis. Cardiovasc Res 55:261–269
55. Nagaya N et al (2004) Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure. Circulation 110:3674–3679
56. National Health Service (2013a) Normative values for cholesterol. http://www.nhs.uk/Conditions/cholesterol/Pages/diagnosis.aspx. Accessed 1 Jan 2015
57. National Health Service (2013b) Physical activity guidelines for adults. http://www.nhs.uk/Livewell/fitness/Pages/physical-activity-guidelines-for-adults.aspx. Accessed 16 Oct 2014
58. Nishina PM, Naggert JK, Verstuyft J, Paigen B (1994) Atherosclerosis in genetically obese mice: the mutants obese, diabetes, fat, tubby, and lethal yellow. Metabolism 43:554–558
59. Office for National Statistics (2012) Population ageing in the united kingdom, its constituent countries and the european union
60. Oggioni C, Lara J, Wells J, Soroka K, Siervo M (2014) Shifts in population dietary patterns and physical inactivity as determinants of global trends in the prevalence of diabetes: an ecological analysis Nutrition. Metab Cardiovasc Dis 24:1105–1111
61. Owen N, Healy GN, Matthews CE, Dunstan DW (2010) Too much sitting: the population-health science of sedentary behavior. Exerc Sport Sci Rev 38:105–113
62. Paffenbarger RS Jr, Hyde R, Wing AL, Hsieh C-C (1986) Physical activity, all-cause mortality, and longevity of college alumni. N Engl J Med 314:605–613
63. Parhami F, Tintut Y, Ballard A, Fogelman AM, Demer LL (2001) Leptin enhances the calcification of vascular cells artery wall as a target of leptin. Circ Res 88:954–960
64. Pate RR, O’Neill JR, Lobelo F (2008) The evolving definition of" sedentary". Exerc Sport Sci Rev 36:173–178
65. Peddie MC, Bone JL, Rehrer NJ, Skeaff CM, Gray AR, Perry TL (2013) Breaking prolonged sitting reduces postprandial glycemia in healthy, normal-weight adults: a randomized crossover trial. Am J Clin Nutr 98:358–366
66. Pescatello LS, Murphy D, Costanzo D (2000) Low-intensity physical activity benefits blood lipids and lipoproteins in older adults living at home. Age Ageing 29:433–439
67. Rios FJ, Koga MM, Pecenin M, Ferracini M, Gidlund M, Jancar S (2013) Oxidized LDL induces alternative macrophage phenotype through activation of CD36 and PAFR. Mediat Inflamm 2013:1–8
68. Rowlands AV et al (2013) Assessing sedentary behavior with the GENEActiv: introducing the sedentary sphere. Med Sci Sports Exerc 46:1235–1247
69. Sallis JF (1985) Leisure and occupational. Off J Am Coll Sports Med 29:S89–S103
70. Shaw JE, Sicree RA, Zimmet PZ (2010) Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 87:4–14
71. Singhal A et al (2002) Influence of leptin on arterial distensibility a novel link between obesity and cardiovascular disease? Circulation 106:1919–1924
72. Spranger J, Kroke A, Möhlig M, Bergmann MM, Ristow M, Boeing H, Pfeiffer AF (2003) Adiponectin and protection against type 2 diabetes mellitus. Lancet 361:226–228
73. Sviridov D, Nestel P (2002) Dynamics of reverse cholesterol transport: protection against atherosclerosis. Atherosclerosis 161:245–254
74. Taddei S, Virdis A, Ghiadoni L, Salvetti G, Bernini G, Magagna A, Salvetti A (2001) Age-related reduction of NO availability and oxidative stress in humans. Hypertension 38:274–279
75. Talayero BG, Sacks FM (2011) The role of triglycerides in atherosclerosis. Curr Cardiol Rep 13:544–552
76. Tremblay MS, Colley RC, Saunders TJ, Healy GN, Owen N (2010) Physiological and health implications of a sedentary lifestyle. Appl Physiol Nutr Metab 35:725–740
77. VanderLaan PA, Reardon CA, Getz GS (2004) Site specificity of atherosclerosis site-selective responses to atherosclerotic modulators Arteriosclerosis. Thrombosis Vasc Biol 24:12–22
78. Vukovich MD, Arciero PJ, Kohrt WM, Racette S, Hansen P, Holloszy J (1996) Changes in insulin action and GLUT-4 with 6 days of inactivity in endurance runners. J Appl Physiol 80:240–244
79. Wang J, Obici S, Morgan K, Barzilai N, Feng Z, Rossetti L (2001) Overfeeding rapidly induces leptin and insulin resistance. Diabetes 50:2786–2791
80. Wang J et al (2013) Leptin‐induced endothelial dysfunction is mediated by sympathetic nervous system activity. J Am Heart Assoc 2:1–8
81. Yamanouchi K et al (1992) Effects of daily physical activity on insulin action in the elderly. J Appl Physiol 73:2241