Breaking prolonged sitting reduces postprandial glycemia in healthy, normal-weight adults: A randomized crossover trial

American Journal of Clinical Nutrition

Volumn 98, Issue 2, 2013, Pages 358-366

  Peddie, Meredith C ^a   Bone, Julia L ^a   Rehrer, Nancy J ^a   Skeaff, C Murray ^a   Gray, Andrew R ^a   Perry, Tracy L ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; TRIACYLGLYCEROL;

ADULT; AEROBIC CAPACITY; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CROSSOVER PROCEDURE; FEMALE; GLUCOSE BLOOD LEVEL; HEART RATE; HUMAN; HYPERLIPIDEMIA; INSULIN BLOOD LEVEL; INSULINEMIA; LUNG GAS EXCHANGE; MALE; NORMAL HUMAN; PHYSICAL ACTIVITY; PROLONGED SITTING; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; SITTING; TEST MEAL; TRIACYLGLYCEROL BLOOD LEVEL; WALKING;

ADULT; AREA UNDER CURVE; BEVERAGES; BLOOD GLUCOSE; BODY MASS INDEX; CARDIOVASCULAR DISEASES; CROSS-OVER STUDIES; DIET; EXERCISE; FEMALE; HUMANS; INSULIN; INTERVENTION STUDIES; MALE; NEW ZEALAND; POSTPRANDIAL PERIOD; RISK FACTORS; SEDENTARY LIFESTYLE; TIME FACTORS; TRIGLYCERIDES; WALKING; YOUNG ADULT;

EID: 84881263729     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.112.051763     Document Type: Article

References (35)

1. Brownson RC, Boehmer T, Luke D. Declining rates of physical activity in the United States: what are the contributors? Annu Rev Public Health 2005;26:421-43.
2. Grøntved A, Hu F. Television viewing and risk of type 2 diabetes, cardiovascular disease, and all-cause mortality: a meta-analysis. JAMA 2011;305:2448-55.
3. Dunstan DW, Barr E, Healy G, Salmon J, Shaw J, Balkau B, Magliano D, Cameron A, Zimmet P, Owen N. Television viewing time and mortality: the Australian Diabetes, Obesity and Lifestyle Study (Aus- Diab). Circulation 2010;121:384-91.
4. Matthews CE, George S, Moore S, Bowles H, Blair A, Park Y, Troiano R, Hollenbeck A, Schatzkin A. Amount of time spent in sedentary behaviors and cause-specific mortality in US adults. Am J Clin Nutr 2012;95:437-45.
5. Healy GN, Dunstan D, Salmon J, Cerin E, Shaw J, Zimmet P, Owen N. Breaks in sedentary time: beneficial associations with metabolic risk. Diabetes Care 2008;31:661-6.
6. Healy GN, Matthews C, Dunstan D, Winkler E, Owen N. Sedentary time and cardio-metabolic biomarkers in US adults: NHANES 2003- 06. Eur Heart J 2011;32:590-7.
7. Stephens BR, Granados K, Zderic T, Hamilton M, Braun B. Effects of 1 day of inactivity on insulin action in healthy men and women: interaction with energy intake. Metabolism 2011;60:941-9.
8. Bey L, Akunuri N, Zhao P, Hoffman E. Patterns of global gene expression in rat skeletal muscle during unloading and low-intensity ambulatory activity. Physiol Genomics 2003;13:157-67.
9. Bey L, Hamilton M. Suppression of skeletal muscle lipoprotein lipase activity during physical inactivity: a molecular reason to maintain daily low-intensity activity. J Physiol 2003;551:673-82.
10. Hamilton MT, Etienne J, McClure W, Pavey B, Holloway A. Role of local contractile activity and muscle fiber type on lpl regulation during exercise. Am J Physiol 1998;275:E1016-22.
11. Zderic TW, Hamilton M. Physical inactivity amplifies the sensitivity of skeletal muscle to the lipid-induced downregulation of lipoprotein lipase activity. J Appl Physiol 2006;100:249-57.
12. Bansal S, Buring J, Rifai N, Mora S, Sacks F, Ridker P. Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women. JAMA 2007;298:309-16.
13. Nordestgaard BG, Benn M, Schnohr P, Tybjaerg-Hansen A. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA 2007;298:299-308.
14. Levitan EB, Song Y, Ford E, Liu S. Is nondiabetic hyperglycemia a risk factor for cardiovascular disease? A meta-analysis of prospective studies. Arch Intern Med 2004;164:2147-55.
15. Ruige JB, Assendelft W, Dekker J, Kostense P, Heine R, Bouter L. Insulin and risk of cardiovascular disease: a meta-analysis. Circulation 1998;97:996-1001.
16. Dunstan DW, Kingwell B, Larsen R, Healy G, Cerin E, Hamilton M, Shaw J, Bertovic D, Zimmet P, Salmon J, et al. Breaking up prolonged sitting reduces postprandial glucose and insulin responses. Diabetes Care 2012;35:976-83.
17. Bruce R. Multi-stage treadmill test of submaximal and maximal exercise. Exercise testing and training of apparently healthy individuals: a handbook for physicians. Dallas, TX: American Heart Assocation, 1972:32-4.
18. Clark S, Youngman L, Palmer A, Peto R, Collins R. Stability of plsma analytes after delayed seperation of whole blood: implications for epidemiological studies. Int J Epidemiol 2003;32:125-30.
19. Giltay EJ, Geleijnes J, Schouten E, Katan M, Kromhout D. High stability of markers of cardiovascular risk in blood samples. Clin Chem 2003;49:652-5.
20. Walters E, Henley R, Barnes I. Stability of insulin in normal whole blood. Clin Chem 1986;32:224.
21. Kenward MG, Roger J. The use of baseline covariates in crossover studies. Biostatistics 2010;11:1-17.
22. Cohn JS, McNamara J, Cohn S, Ordovas J, Schaefer E. Postprandial plasma lipoprotein changes in human subjects of different ages. J Lipid Res 1988;29:469-79.
23. Jackson KG, Abraham E, Smith A, Murray P, O'Malley B, Williams C, Minihane A. Impact of age and menopausal status on the postprandial triacylglycerol response in healthy women. Atherosclerosis 2010;208: 246-52.
24. Jackson KG, Knapper-Francis J, Morgan L, Webb D, Zampelas A, Williams C. Exaggerated postprandial lipaemia and lower postheparin lipoprotein lipase activity in middle aged men. Clin Sci 2003;105:457-66.
25. Peddie MC, Rehrer N, Perry T. Physical activity and postprandial lipidemia: are energy expenditure and lipoprotein lipase activity the real modulators of the positive effect? Prog Lipid Res 2012;51:11-22.
26. Haskell WL, Lee I, Pate R, Powell K, Blair S, Franklin B, Macera C, Heath G, Thompson P, Bauman A. Physical activity and public health: updated recommendations for adults from the American College of Sports Medicine and the American Heart Association. Med Sci Sports Exerc 2007;39:1423-34.
27. Magkos F, Tsekouras Y, Kavouras S, Mittendorfer B, Sidossis L. Improved insulin sensitivity after a single bout of exercise is curvilinearly related to exercise energy expenditure. Clin Sci 2008;114:59-64.
28. Holloszy JO, Narahara H. Changes in permeability to 3-methylglucose assocaited with contraction of isolated frog muscle. J Biol Chem 1965; 240:3493-500.
29. Holloszy JO. Exercise-induced increase in muscle insulin sensitivity. J Appl Physiol 2005;99:338-43.
30. Zhang X, Gregg EW, Williamson DF, Barker LE, Thomas W, Bullard KM, Imperatore G, Williams DE, Albright AL. A1c level and future risk of diabetes: a systematic review. Diabetes Care 2010;33:1665-73.
31. Aryangat AV, Gerich J. Type 2 diabetes: postprandial hyperglycemia and increased cardiovascular risk. Vasc Health Risk Manag 2010;6: 145-55.
32. Gill JM, Herd S, Vora V, Hardman A. Effects of a brisk walk on lipoprotein lipase activity and plasma triglyceride concentrations in the fasted and postprandial states. Eur J Appl Physiol 2003;89:184-90.
33. Herd SL, Kiens B, Boobis L, Hardman A. Moderate exercise, postprandial lipemia, and skeletal muscle lipoprotein lipase activity. Metabolism 2001;50:756-62.
34. Miyashita M, Burns S, Stensel D. Accumulating short bouts of brisk walking reduces postprandial plasma triacylglycerol concentrations and resting blood pressure in healthy young men. Am J Clin Nutr 2008; 88:1225-31.
35. Frayn KN. Fat as a fuel: emerging understanding of the adipose tissueskeletal muscle axis. Acta Physiol (Oxf) 2010;199:509-18.