메뉴 건너뛰기




Volumn 4, Issue 8, 2015, Pages

Antitumor activity of epigenetic immunomodulation combined with CTLA-4 blockade in syngeneic mouse models

Author keywords

cancer; CTLA 4; DNA methylation; immune responses; immunomodulation; immunotherapy

Indexed keywords

9H10 MONOCLONAL ANTIBODY; ANTINEOPLASTIC AGENT; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DECITABINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; UNCLASSIFIED DRUG;

EID: 84940473692     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.1080/2162402X.2015.1019978     Document Type: Article
Times cited : (64)

References (34)
  • 2
    • 84898893534 scopus 로고    scopus 로고
    • Epigenetic drugs as immunomodulators for combination therapies in solid tumors
    • 24384533
    • L.Sigalotti, E.Fratta, S.Coral, M.Maio. Epigenetic drugs as immunomodulators for combination therapies in solid tumors. Pharmacol Ther 2014; 142(3):339-50; PMID:24384533; http://dx.doi.org/10.1016/j.pharmthera.2013.12.015
    • (2014) Pharmacol Ther , vol.142 , Issue.3 , pp. 339-350
    • Sigalotti, L.1    Fratta, E.2    Coral, S.3    Maio, M.4
  • 4
    • 10844289762 scopus 로고    scopus 로고
    • Intratumor heterogeneity of cancer/testis antigens expression in human cutaneous melanoma is methylation-regulated and functionally reverted by 5-aza-2′-deoxycytidine
    • 15604288
    • L.Sigalotti, E.Fratta, S.Coral, S.Tanzarella, R.Danielli, F.Colizzi, E.Fonsatti, C.Traversari, M.Altomonte, M.Maio. Intratumor heterogeneity of cancer/testis antigens expression in human cutaneous melanoma is methylation-regulated and functionally reverted by 5-aza-2′-deoxycytidine. Cancer Research. 2004; 64(24):9167-71; PMID:15604288; http://dx.doi.org/10.1158/0008-5472.CAN-04-1442
    • (2004) Cancer Research , vol.64 , Issue.24 , pp. 9167-9171
    • Sigalotti, L.1    Fratta, E.2    Coral, S.3    Tanzarella, S.4    Danielli, R.5    Colizzi, F.6    Fonsatti, E.7    Traversari, C.8    Altomonte, M.9    Maio, M.10
  • 5
    • 34250621776 scopus 로고    scopus 로고
    • Functional up-regulation of human leukocyte antigen class I antigens expression by 5-aza-2′-deoxycytidine in cutaneous melanoma: immunotherapeutic implications
    • 17545540
    • E.Fonsatti, H.J.Nicolay, L.Sigalotti, L.Calabro, L.Pezzani, F.Colizzi,, M.Altomonte, M.Guidoboni, F.M.Marincola, M.Maio. Functional up-regulation of human leukocyte antigen class I antigens expression by 5-aza-2′-deoxycytidine in cutaneous melanoma: immunotherapeutic implications. Clin Cancer Res 2007; 13(11):3333-38; PMID:17545540; http://dx.doi.org/10.1158/1078-0432.CCR-06-3091
    • (2007) Clin Cancer Res , vol.13 , Issue.11 , pp. 3333-3338
    • Fonsatti, E.1    Nicolay, H.J.2    Sigalotti, L.3    Calabro, L.4    Pezzani, L.5    Colizzi, F.6    Altomonte, M.7    Guidoboni, M.8    Marincola, F.M.9    Maio, M.10
  • 6
    • 84866927969 scopus 로고    scopus 로고
    • Epigenetic remodelling of gene expression profiles of neoplastic and normal tissues: immunotherapeutic implications
    • 22910318
    • S.Coral, A.Covre, H.J.Nicolay, G.Parisi, A.Rizzo, F.Colizzi, S.Dalla Santa, E.Fonsatti, E.Fratta, L.Sigalotti et al. Epigenetic remodelling of gene expression profiles of neoplastic and normal tissues: immunotherapeutic implications. Br J Cancer 2012; 107(7):1116-24; PMID:22910318; http://dx.doi.org/10.1038/bjc.2012.361
    • (2012) Br J Cancer , vol.107 , Issue.7 , pp. 1116-1124
    • Coral, S.1    Covre, A.2    Nicolay, H.J.3    Parisi, G.4    Rizzo, A.5    Colizzi, F.6    Dalla Santa, S.7    Fonsatti, E.8    Fratta, E.9    Sigalotti, L.10
  • 7
    • 0032920527 scopus 로고    scopus 로고
    • Prolonged upregulation of the expression of HLA class I antigens and costimulatory molecules on melanoma cells treated with 5-aza-2′-deoxycytidine (5-AZA-CdR)
    • 9924695
    • S.Coral, L.Sigalotti, A.Gasparollo, I.Cattarossi, A.Visintin, A.Cattelan, M.Altomonte, M.Maio. Prolonged upregulation of the expression of HLA class I antigens and costimulatory molecules on melanoma cells treated with 5-aza-2′-deoxycytidine (5-AZA-CdR). J Immunother 1999; 22(1):16-24; PMID:9924695; http://dx.doi.org/10.1097/00002371-199901000-00003
    • (1999) J Immunother , vol.22 , Issue.1 , pp. 16-24
    • Coral, S.1    Sigalotti, L.2    Gasparollo, A.3    Cattarossi, I.4    Visintin, A.5    Cattelan, A.6    Altomonte, M.7    Maio, M.8
  • 8
    • 84929159881 scopus 로고    scopus 로고
    • Epigenetics meets immune checkpoints. Semin Oncol
    • 506-513
    • A.Covre, S.Coral, A.M.Di Giacomo, P.Taverna, M.Azab, M.Maio. Epigenetics meets immune checkpoints. Semin Oncol. Cancer Res 2015; 42(3):506-513;http://dx.doi.org/10.1053/j.seminoncol2015.02.00315
    • (2015) Cancer Res , vol.42 , Issue.3
    • Covre, A.1    Coral, S.2    Di Giacomo, A.M.3    Taverna, P.4    Azab, M.5    Maio, M.6
  • 9
    • 78449251207 scopus 로고    scopus 로고
    • Clinical studies with anti-CTLA-4 antibodies in non-melanoma indications
    • 21074061
    • L.Calabro, R.Danielli, L.Sigalotti, M.Maio. Clinical studies with anti-CTLA-4 antibodies in non-melanoma indications. Semin Oncol 2010; 37(5):460-67; PMID:21074061; http://dx.doi.org/10.1053/j.seminoncol.2010.09.006
    • (2010) Semin Oncol , vol.37 , Issue.5 , pp. 460-467
    • Calabro, L.1    Danielli, R.2    Sigalotti, L.3    Maio, M.4
  • 10
    • 84899128381 scopus 로고    scopus 로고
    • Immune checkpoint blockade in malignant mesothelioma: A novel therapeutic strategy against a deadly disease?
    • 24734215
    • L.Calabro, M.Maio. Immune checkpoint blockade in malignant mesothelioma: A novel therapeutic strategy against a deadly disease? Oncoimmunology 2014; 3(1):e27482; PMID:24734215; http://dx.doi.org/10.4161/onci.27482
    • (2014) Oncoimmunology , vol.3 , Issue.1 , pp. 27482
    • Calabro, L.1    Maio, M.2
  • 11
    • 84873714872 scopus 로고    scopus 로고
    • Update on the role of ipilimumab in melanoma and first data on new combination therapies
    • 23299197
    • M.Maio, A.M.Di Giacomo, C.Robert, A.M.Eggermont. Update on the role of ipilimumab in melanoma and first data on new combination therapies. Curr Opin Oncol 2013; 25(2):166-72; PMID:23299197; http://dx.doi.org/10.1097/CCO.0b013e32835dae4f
    • (2013) Curr Opin Oncol , vol.25 , Issue.2 , pp. 166-172
    • Maio, M.1    Di Giacomo, A.M.2    Robert, C.3    Eggermont, A.M.4
  • 12
    • 84880310548 scopus 로고    scopus 로고
    • Four-year survival rates for patients with metastatic melanoma who received ipilimumab in phase II clinical trials
    • 23666915
    • J.D.Wolchok, J.S.Weber, M.Maio, B.Neyns, K.Harmankaya, K.Chin, L.Cykowski,, V.de Pril, R.Humphrey, C.Lebbe. Four-year survival rates for patients with metastatic melanoma who received ipilimumab in phase II clinical trials. Ann Oncol 2013; 24(8):2174-80; PMID:23666915; http://dx.doi.org/10.1093/annonc/mdt161
    • (2013) Ann Oncol , vol.24 , Issue.8 , pp. 2174-2180
    • Wolchok, J.D.1    Weber, J.S.2    Maio, M.3    Neyns, B.4    Harmankaya, K.5    Chin, K.6    Cykowski, L.7    de Pril, V.8    Humphrey, R.9    Lebbe, C.10
  • 13
    • 84878875962 scopus 로고    scopus 로고
    • Long-term survival and immunological parameters in metastatic melanoma patients who responded to ipilimumab 10 mg/kg within an expanded access programme
    • 23591982
    • A.M.Di Giacomo, L.Calabro, R.Danielli, E.Fonsatti, E.Bertocci, I.Pesce, C.Fazio, O.Cutaia, D.Giannarelli, C.Miracco et al. Long-term survival and immunological parameters in metastatic melanoma patients who responded to ipilimumab 10 mg/kg within an expanded access programme. Cancer Immunol Immunother 2013; 62(6):1021-28; PMID:23591982; http://dx.doi.org/10.1007/s00262-013-1418-6
    • (2013) Cancer Immunol Immunother , vol.62 , Issue.6 , pp. 1021-1028
    • Di Giacomo, A.M.1    Calabro, L.2    Danielli, R.3    Fonsatti, E.4    Bertocci, E.5    Pesce, I.6    Fazio, C.7    Cutaia, O.8    Giannarelli, D.9    Miracco, C.10
  • 15
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • 22437870
    • D.M.Pardoll. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 2012; 12(4):252-64; PMID:22437870; http://dx.doi.org/10.1038/nrc3239
    • (2012) Nat Rev Cancer , vol.12 , Issue.4 , pp. 252-264
    • Pardoll, D.M.1
  • 16
    • 78449243489 scopus 로고    scopus 로고
    • Immune checkpoint proteins: a new therapeutic paradigm for cancer-preclinical background: CTLA-4 and PD-1 blockade
    • 21074057
    • J.Weber. Immune checkpoint proteins: a new therapeutic paradigm for cancer-preclinical background: CTLA-4 and PD-1 blockade. Semin Oncol 2010; 37(5):430-39; PMID:21074057; http://dx.doi.org/10.1053/j.seminoncol.2010.09.005
    • (2010) Semin Oncol , vol.37 , Issue.5 , pp. 430-439
    • Weber, J.1
  • 17
    • 79955785050 scopus 로고    scopus 로고
    • Combination CTLA-4 blockade and 4-1BB activation enhances tumor rejection by increasing T-cell infiltration, proliferation, and cytokine production
    • 21559358
    • M.A.Curran, M.Kim, W.Montalvo, A.Al-Shamkhani, J.P.Allison. Combination CTLA-4 blockade and 4-1BB activation enhances tumor rejection by increasing T-cell infiltration, proliferation, and cytokine production. PLoS One 2011; 6(4):e19499; PMID:21559358; http://dx.doi.org/10.1371/journal.pone.0019499
    • (2011) PLoS One , vol.6 , Issue.4 , pp. 19499
    • Curran, M.A.1    Kim, M.2    Montalvo, W.3    Al-Shamkhani, A.4    Allison, J.P.5
  • 18
    • 0033517152 scopus 로고    scopus 로고
    • Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation
    • 10430624
    • A.Van Elsas, A.A.Hurwitz, J.P.Allison. Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation. J Exp Med 1999; 190(3):355-66; PMID:10430624; http://dx.doi.org/10.1084/jem.190.3.355
    • (1999) J Exp Med , vol.190 , Issue.3 , pp. 355-366
    • Van Elsas, A.1    Hurwitz, A.A.2    Allison, J.P.3
  • 19
    • 84870255287 scopus 로고    scopus 로고
    • Patient responses to ipilimumab, a novel immunopotentiator for metastatic melanoma: how different are these from conventional treatment responses?
    • 21336089
    • G.K.Pennock, W.Waterfield, J.D.Wolchok. Patient responses to ipilimumab, a novel immunopotentiator for metastatic melanoma: how different are these from conventional treatment responses? Am J Clin Oncol 2012; 35(6):606-11; PMID:21336089; http://dx.doi.org/10.1097/COC.0b013e318209cda9
    • (2012) Am J Clin Oncol , vol.35 , Issue.6 , pp. 606-611
    • Pennock, G.K.1    Waterfield, W.2    Wolchok, J.D.3
  • 20
    • 73149092567 scopus 로고    scopus 로고
    • Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria
    • 19934295
    • J.D.Wolchok, A.Hoos, S.O'Day, J.S.Weber, O.Hamid, C.Lebbe, M.Maio, M.Binder, O.Bohnsack, G.Nichol et al. Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin Cancer Res 2009; 15(23):7412-20; PMID:19934295; http://dx.doi.org/10.1158/1078-0432.CCR-09-1624
    • (2009) Clin Cancer Res , vol.15 , Issue.23 , pp. 7412-7420
    • Wolchok, J.D.1    Hoos, A.2    O'Day, S.3    Weber, J.S.4    Hamid, O.5    Lebbe, C.6    Maio, M.7    Binder, M.8    Bohnsack, O.9    Nichol, G.10
  • 22
    • 77749279776 scopus 로고    scopus 로고
    • PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
    • 20160101
    • M.A.Curran, W.Montalvo, H.Yagita, J.P.Allison. PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors. Proc Natl Acad Sci U S A 2010; 107(9):4275-80; PMID:20160101; http://dx.doi.org/10.1073/pnas.0915174107
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.9 , pp. 4275-4280
    • Curran, M.A.1    Montalvo, W.2    Yagita, H.3    Allison, J.P.4
  • 23
    • 0033213599 scopus 로고    scopus 로고
    • CTLA-4 blockade reverses CD8+ T cell tolerance to tumor by a CD4+ T cell- and IL-2-dependent mechanism
    • 10549630
    • P.Shrikant, A.Khoruts, M.F.Mescher. CTLA-4 blockade reverses CD8+ T cell tolerance to tumor by a CD4+ T cell- and IL-2-dependent mechanism. Immunity 1999; 11(4):483-93; PMID:10549630; http://dx.doi.org/10.1016/S1074-7613(00)80123-5
    • (1999) Immunity , vol.11 , Issue.4 , pp. 483-493
    • Shrikant, P.1    Khoruts, A.2    Mescher, M.F.3
  • 24
    • 84890288009 scopus 로고    scopus 로고
    • Immune-mediated adverse events associated with ipilimumab ctla-4 blockade therapy: the underlying mechanisms and clinical management
    • 24278787
    • A.Tarhini. Immune-mediated adverse events associated with ipilimumab ctla-4 blockade therapy: the underlying mechanisms and clinical management. Scientifica (Cairo) 2013:857519; PMID:24278787; http://dx.doi.org/10.1155/2013/857519
    • (2013) Scientifica (Cairo) , pp. 857519
    • Tarhini, A.1
  • 25
    • 84864052441 scopus 로고    scopus 로고
    • Management of immune-related adverse events and kinetics of response with ipilimumab
    • 22614989
    • J.S.Weber, K.C.Kahler, A.Hauschild. Management of immune-related adverse events and kinetics of response with ipilimumab. J Clin Oncol 2012; 30(21):2691-97; PMID:22614989; http://dx.doi.org/10.1200/JCO.2012.41.6750
    • (2012) J Clin Oncol , vol.30 , Issue.21 , pp. 2691-2697
    • Weber, J.S.1    Kahler, K.C.2    Hauschild, A.3
  • 26
    • 84919964373 scopus 로고    scopus 로고
    • Improved mouse models to assess tumour immunity and irAEs after combination cancer immunotherapies
    • 25505970
    • J.Liu, S.J.Blake, M.J.Smyth, M.W.L.Teng. Improved mouse models to assess tumour immunity and irAEs after combination cancer immunotherapies. Clin Transl Immunol 2014; 3:e22; PMID:25505970; http://dx.doi.org/10.1038/cti.2014.18
    • (2014) Clin Transl Immunol , vol.3 , pp. 22
    • Liu, J.1    Blake, S.J.2    Smyth, M.J.3    Teng, M.W.L.4
  • 27
    • 0021077888 scopus 로고
    • TS/A: a new metastasizing cell line from a BALB/c spontaneous mammary adenocarcinoma
    • 6546207
    • P.Nanni, C.De Giovanni, P.L.Lollini, G.Nicoletti, G.Prodi. TS/A: a new metastasizing cell line from a BALB/c spontaneous mammary adenocarcinoma. Clin Exp Metastasis 1983; 1(4):373-80; PMID:6546207; http://dx.doi.org/10.1007/BF00121199
    • (1983) Clin Exp Metastasis , vol.1 , Issue.4 , pp. 373-380
    • Nanni, P.1    De Giovanni, C.2    Lollini, P.L.3    Nicoletti, G.4    Prodi, G.5
  • 28
    • 0026620586 scopus 로고
    • Establishment of a murine model of malignant mesothelioma
    • 1459729
    • M.R.Davis, L.S.Manning, D.Whitaker, M.J.Garlepp, B.W.Robinson. Establishment of a murine model of malignant mesothelioma. Int J Cancer 1992; 52(6):881-86; PMID:1459729; http://dx.doi.org/10.1002/ijc.2910520609
    • (1992) Int J Cancer , vol.52 , Issue.6 , pp. 881-886
    • Davis, M.R.1    Manning, L.S.2    Whitaker, D.3    Garlepp, M.J.4    Robinson, B.W.5
  • 30
    • 31544432509 scopus 로고    scopus 로고
    • De novo induction of a cancer/testis antigen by 5-aza-2′-deoxycytidine augments adoptive immunotherapy in a murine tumor model
    • 16424047
    • Z.S.Guo, J.A.Hong, K.R.Irvine, G.A.Chen, P.J.Spiess, Y.Liu, G.Zeng, J.R.Wunderlich, D.M.Nguyen, N.P.Restifo et al. De novo induction of a cancer/testis antigen by 5-aza-2′-deoxycytidine augments adoptive immunotherapy in a murine tumor model. Cancer Res 2006; 66(2):1105-13; PMID:16424047; http://dx.doi.org/10.1158/0008-5472.CAN-05-3020
    • (2006) Cancer Res , vol.66 , Issue.2 , pp. 1105-1113
    • Guo, Z.S.1    Hong, J.A.2    Irvine, K.R.3    Chen, G.A.4    Spiess, P.J.5    Liu, Y.6    Zeng, G.7    Wunderlich, J.R.8    Nguyen, D.M.9    Restifo, N.P.10
  • 32
    • 0036856355 scopus 로고    scopus 로고
    • MethPrimer: designing primers for methylation PCRs
    • 12424112
    • L.C.Li, R.Dahiya. MethPrimer: designing primers for methylation PCRs. Bioinformatics 2002; 18(11):1427-31; PMID:12424112; http://dx.doi.org/10.1093/bioinformatics/18.11.1427
    • (2002) Bioinformatics , vol.18 , Issue.11 , pp. 1427-1431
    • Li, L.C.1    Dahiya, R.2
  • 33
    • 0019364279 scopus 로고
    • Monoclonal antibodies to mouse MHC antigens. III. Hybridoma antibodies reacting to antigens of the H-2b haplotype reveal genetic control of isotype expression
    • 6935293
    • K.Ozato, D.H.Sachs. Monoclonal antibodies to mouse MHC antigens. III. Hybridoma antibodies reacting to antigens of the H-2b haplotype reveal genetic control of isotype expression. J Immunol 1981; 126(1):317-21; PMID:6935293
    • (1981) J Immunol , vol.126 , Issue.1 , pp. 317-321
    • Ozato, K.1    Sachs, D.H.2
  • 34
    • 0032534727 scopus 로고    scopus 로고
    • A region of conformational variability outside the peptide-binding site of a class I MHC molecule
    • 9862704
    • S.T.Kuhns, L.R.Pease. A region of conformational variability outside the peptide-binding site of a class I MHC molecule. J Immunol 1998; 161(12):6745-50; PMID:9862704
    • (1998) J Immunol , vol.161 , Issue.12 , pp. 6745-6750
    • Kuhns, S.T.1    Pease, L.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.