메뉴 건너뛰기




Volumn 47, Issue 9, 2015, Pages 1817-1826

Association of homoarginine and methylarginines with liver dysfunction and mortality in chronic liver disease

Author keywords

ADMA; Amino acids; Cirrhosis; Dimethylarginine score; Homoarginine; SDMA

Indexed keywords

6 N,N' DIMETHYLARGININE; HOMOARGININE; N(G),N(G) DIMETHYLARGININE; ARGININE; DIMETHYLARGININE; N,N-DIMETHYLARGININE;

EID: 84940459576     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-015-2000-7     Document Type: Article
Times cited : (22)

References (46)
  • 3
    • 55749095687 scopus 로고    scopus 로고
    • The l-arginine/NO pathway in end-stage liver disease and during orthotopic liver and kidney transplantation: Biological and analytical ramifications
    • 1:CAS:528:DC%2BD1cXhsVSjs7bM 18948222
    • Becker T, Mevius I, de Vries DK, Schaapherder AF, zu Vilsendorf AM, Klempnauer J, Frölich JC, Tsikas D (2009) The l-arginine/NO pathway in end-stage liver disease and during orthotopic liver and kidney transplantation: biological and analytical ramifications. Nitric Oxide 20:61-67
    • (2009) Nitric Oxide , vol.20 , pp. 61-67
    • Becker, T.1    Mevius, I.2    De Vries, D.K.3    Schaapherder, A.F.4    Zu Vilsendorf, A.M.5    Klempnauer, J.6    Frölich, J.C.7    Tsikas, D.8
  • 5
    • 77951768942 scopus 로고    scopus 로고
    • Genetic loci influencing kidney function and chronic kidney disease
    • 3748585 1:CAS:528:DC%2BC3cXksFakurk%3D 20383145
    • Chambers JC, Zhang W, Lord GM, van der Harst P, Lawlor DA, Sehmi JS et al (2010) Genetic loci influencing kidney function and chronic kidney disease. Nat Genet 42:373-375
    • (2010) Nat Genet , vol.42 , pp. 373-375
    • Chambers, J.C.1    Zhang, W.2    Lord, G.M.3    Van Der Harst, P.4    Lawlor, D.A.5    Sehmi, J.S.6
  • 6
    • 33747163976 scopus 로고    scopus 로고
    • Myocardial expression of the arginine:glycine amidinotransferase gene is elevated in heart failure and normalized after recovery: Potential implications for local creatine synthesis
    • 16820567
    • Cullen ME, Yuen AH, Felkin LE, Smolenski RT, Hall JL, Grindle S, Miller LW, Birks EJ, Yacoub MH, Barton PJ (2006) Myocardial expression of the arginine:glycine amidinotransferase gene is elevated in heart failure and normalized after recovery: potential implications for local creatine synthesis. Circulation 114(1 Suppl):I16-I20
    • (2006) Circulation , vol.114 , Issue.1 , pp. I16-I20
    • Cullen, M.E.1    Yuen, A.H.2    Felkin, L.E.3    Smolenski, R.T.4    Hall, J.L.5    Grindle, S.6    Miller, L.W.7    Birks, E.J.8    Yacoub, M.H.9    Barton, P.J.10
  • 9
    • 64549140736 scopus 로고    scopus 로고
    • Relationship between cerebral arterial pulsatility and carotid intima media thickness in diabetic and non-diabetic patients with non-alcoholic fatty liver disease
    • 1:CAS:528:DC%2BD1MXlvVWnsrg%3D 19337018
    • Karakurt F, Carlioglu A, Koktener A, Ozbek M, Kaya A, Uyar ME, Kasapoglu B, Ilhan A (2009) Relationship between cerebral arterial pulsatility and carotid intima media thickness in diabetic and non-diabetic patients with non-alcoholic fatty liver disease. J Endocrinol Invest 32:63-68
    • (2009) J Endocrinol Invest , vol.32 , pp. 63-68
    • Karakurt, F.1    Carlioglu, A.2    Koktener, A.3    Ozbek, M.4    Kaya, A.5    Uyar, M.E.6    Kasapoglu, B.7    Ilhan, A.8
  • 10
    • 79956063329 scopus 로고    scopus 로고
    • Plasma levels of asymmetric dimethylarginine in patients with biopsy-proven nonalcoholic fatty liver disease
    • 3012158 1:CAS:528:DC%2BC3MXmtFaltb0%3D 20869086
    • Kasumov T, Edmison JM, Dasarathy S, Bennett C, Lopez R, Kalhan SC (2011) Plasma levels of asymmetric dimethylarginine in patients with biopsy-proven nonalcoholic fatty liver disease. Metabolism 60:776-781
    • (2011) Metabolism , vol.60 , pp. 776-781
    • Kasumov, T.1    Edmison, J.M.2    Dasarathy, S.3    Bennett, C.4    Lopez, R.5    Kalhan, S.C.6
  • 12
    • 67349175651 scopus 로고    scopus 로고
    • Multiple loci associated with indices of renal function and chronic kidney disease
    • 3039280 19430482
    • Köttgen A, Glazer NL, Dehghan A, Hwang SJ, Katz R, Li M et al (2009) Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet 41:712-717
    • (2009) Nat Genet , vol.41 , pp. 712-717
    • Köttgen, A.1    Glazer, N.L.2    Dehghan, A.3    Hwang, S.J.4    Katz, R.5    Li, M.6
  • 14
    • 70349306439 scopus 로고    scopus 로고
    • Coordinated regulation of dimethylarginine dimethylaminohydrolase-1 and cationic amino acid transporter-1 by farnesoid X receptor in mouse liver and kidney and its implication in the control of blood levels of asymmetric dimethylarginine
    • 2766229 1:CAS:528:DC%2BD1MXht1GjtL%2FP 19605523
    • Li J, Wilson A, Gao X, Liu Y, Poloyac S, Pitt B, Xie W, Li S (2009) Coordinated regulation of dimethylarginine dimethylaminohydrolase-1 and cationic amino acid transporter-1 by farnesoid X receptor in mouse liver and kidney and its implication in the control of blood levels of asymmetric dimethylarginine. J Pharmacol Exp Ther 331:234-243
    • (2009) J Pharmacol Exp Ther , vol.331 , pp. 234-243
    • Li, J.1    Wilson, A.2    Gao, X.3    Liu, Y.4    Poloyac, S.5    Pitt, B.6    Xie, W.7    Li, S.8
  • 15
    • 3442882166 scopus 로고    scopus 로고
    • Plasma concentrations of nitric oxide and asymmetric dimethylarginine in human alcoholic cirrhosis
    • 1:CAS:528:DC%2BD2cXls1WnsLo%3D 15246208
    • Lluch P, Torondel B, Medina P, Segarra G, Del Olmo JA, Serra MA, Rodrigo JM (2004) Plasma concentrations of nitric oxide and asymmetric dimethylarginine in human alcoholic cirrhosis. J Hepatol 41:55-59
    • (2004) J Hepatol , vol.41 , pp. 55-59
    • Lluch, P.1    Torondel, B.2    Medina, P.3    Segarra, G.4    Del Olmo, J.A.5    Serra, M.A.6    Rodrigo, J.M.7
  • 20
    • 34547901469 scopus 로고    scopus 로고
    • Reference values for plasma concentrations of asymmetrical dimethylarginine (ADMA) and other arginine metabolites in men after validation of a chromatographic method
    • 1:CAS:528:DC%2BD2sXpt1Sksbw%3D 17689511
    • Meinitzer A, Puchinger M, Winklhofer-Roob BM, Rock E, Ribalta J, Roob JM, Sundl I, Halwachs-Baumann G, März W (2007) Reference values for plasma concentrations of asymmetrical dimethylarginine (ADMA) and other arginine metabolites in men after validation of a chromatographic method. Clin Chim Acta 384:141-148
    • (2007) Clin Chim Acta , vol.384 , pp. 141-148
    • Meinitzer, A.1    Puchinger, M.2    Winklhofer-Roob, B.M.3    Rock, E.4    Ribalta, J.5    Roob, J.M.6    Sundl, I.7    Halwachs-Baumann, G.8    März, W.9
  • 22
    • 78650993607 scopus 로고    scopus 로고
    • Symmetrical and asymmetrical dimethylarginine as predictors for mortality in patients referred for coronary angiography: The Ludwigshafen Risk and Cardiovascular Health study
    • 1:CAS:528:DC%2BC3MXitFSksrw%3D 21036946
    • Meinitzer A, Kielstein JT, Pilz S, Drechsler C, Ritz E, Boehm BO, Winkelmann BR, März W (2011b) Symmetrical and asymmetrical dimethylarginine as predictors for mortality in patients referred for coronary angiography: the Ludwigshafen Risk and Cardiovascular Health study. Clin Chem 57:112-121
    • (2011) Clin Chem , vol.57 , pp. 112-121
    • Meinitzer, A.1    Kielstein, J.T.2    Pilz, S.3    Drechsler, C.4    Ritz, E.5    Boehm, B.O.6    Winkelmann, B.R.7    März, W.8
  • 24
    • 33947423436 scopus 로고    scopus 로고
    • Inflammation is an important determinant of levels of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine (ADMA) in acute liver failure
    • 17318866
    • Mookerjee RP, Dalton RN, Davies NA, Hodges SJ, Turner C, Williams R, Jalan R (2007b) Inflammation is an important determinant of levels of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine (ADMA) in acute liver failure. Liver Transpl 13:400-405
    • (2007) Liver Transpl , vol.13 , pp. 400-405
    • Mookerjee, R.P.1    Dalton, R.N.2    Davies, N.A.3    Hodges, S.J.4    Turner, C.5    Williams, R.6    Jalan, R.7
  • 25
    • 12244262222 scopus 로고    scopus 로고
    • Asymmetrical dimethylarginine (ADMA) in critically ill patients: High plasma ADMA concentration is an independent risk factor of ICU mortality
    • 1:CAS:528:DC%2BD3sXmt1Sluw%3D%3D 12553946
    • Nijveldt RJ, Teerlink T, Van Der Hoven B, Siroen MP, Kuik DJ, Rauwerda JA, van Leeuwen PA (2003a) Asymmetrical dimethylarginine (ADMA) in critically ill patients: high plasma ADMA concentration is an independent risk factor of ICU mortality. Clin Nutr 22:23-30
    • (2003) Clin Nutr , vol.22 , pp. 23-30
    • Nijveldt, R.J.1    Teerlink, T.2    Van Der Hoven, B.3    Siroen, M.P.4    Kuik, D.J.5    Rauwerda, J.A.6    Van Leeuwen, P.A.7
  • 28
    • 79954637472 scopus 로고    scopus 로고
    • Low serum homoarginine is a novel risk factor for fatal strokes in patients undergoing coronary angiography
    • 1:CAS:528:DC%2BC3MXjvVOjsLo%3D 21311067
    • Pilz S, Tomaschitz A, Meinitzer A, Drechsler C, Ritz E, Krane V, Wanner C, Bohm BO, März W (2011a) Low serum homoarginine is a novel risk factor for fatal strokes in patients undergoing coronary angiography. Stroke 42:1132-1134
    • (2011) Stroke , vol.42 , pp. 1132-1134
    • Pilz, S.1    Tomaschitz, A.2    Meinitzer, A.3    Drechsler, C.4    Ritz, E.5    Krane, V.6    Wanner, C.7    Bohm, B.O.8    März, W.9
  • 33
    • 54249083520 scopus 로고    scopus 로고
    • The prominent role of the liver in the elimination of asymmetric dimethylarginine (ADMA) and the consequences of impaired hepatic function
    • 1:CAS:528:DC%2BD1cXhsVarsL3E 18974239
    • Richir MC, Bouwman RH, Teerlink T, Siroen MP, de Vries TP, van Leeuwen PA (2008) The prominent role of the liver in the elimination of asymmetric dimethylarginine (ADMA) and the consequences of impaired hepatic function. JPEN J Parenter Enteral Nutr 32:613-621
    • (2008) JPEN J Parenter Enteral Nutr , vol.32 , pp. 613-621
    • Richir, M.C.1    Bouwman, R.H.2    Teerlink, T.3    Siroen, M.P.4    De Vries, T.P.5    Van Leeuwen, P.A.6
  • 34
    • 0015338388 scopus 로고
    • L-Homoarginine, a specific inhibitor of liver-type alkaline phosphatase, applied to the recognition of liver-type enzyme activity in rat intestine
    • 1:CAS:528:DyaE38XhsFSgsLw%3D 5023163
    • Rufo MB, Fishman WH (1972) l-Homoarginine, a specific inhibitor of liver-type alkaline phosphatase, applied to the recognition of liver-type enzyme activity in rat intestine. J Histochem Cytochem 20:336-343
    • (1972) J Histochem Cytochem , vol.20 , pp. 336-343
    • Rufo, M.B.1    Fishman, W.H.2
  • 35
    • 0343811639 scopus 로고
    • Homocitrulline and homoarginine synthesis from lysine
    • 1:CAS:528:DyaF2cXkt1Ont7s%3D 14148430
    • Ryan WL, Wells IC (1964) Homocitrulline and homoarginine synthesis from lysine. Science 144:1122-1127
    • (1964) Science , vol.144 , pp. 1122-1127
    • Ryan, W.L.1    Wells, I.C.2
  • 38
    • 0037089509 scopus 로고    scopus 로고
    • Determination of arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in human plasma and other biological samples by high-performance liquid chromatography
    • 1:CAS:528:DC%2BD38XislSgur8%3D 11950212
    • Teerlink T, Nijveldt RJ, de Jong S, van Leeuwen PA (2002) Determination of arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in human plasma and other biological samples by high-performance liquid chromatography. Anal Biochem 303:131-137
    • (2002) Anal Biochem , vol.303 , pp. 131-137
    • Teerlink, T.1    Nijveldt, R.J.2    De Jong, S.3    Van Leeuwen, P.A.4
  • 39
    • 84904994046 scopus 로고    scopus 로고
    • Do Homoarginine and asymmetric dimethylarginine act antagonistically in the cardiovascular system?
    • 24931514
    • Tsikas D, Kayacelebi AA (2014) Do Homoarginine and asymmetric dimethylarginine act antagonistically in the cardiovascular system? Circ J 78:2094-2095
    • (2014) Circ J , vol.78 , pp. 2094-2095
    • Tsikas, D.1    Kayacelebi, A.A.2
  • 40
    • 0342757751 scopus 로고    scopus 로고
    • Endogenous nitric oxide synthase inhibitors are responsible for the l-arginine paradox
    • 1:CAS:528:DC%2BD3cXltVGrsL0%3D 10922458
    • Tsikas D, Böger RH, Sandmann J, Bode-Böger SM, Frölich JC (2000a) Endogenous nitric oxide synthase inhibitors are responsible for the l-arginine paradox. FEBS Lett 478:1-3
    • (2000) FEBS Lett , vol.478 , pp. 1-3
    • Tsikas, D.1    Böger, R.H.2    Sandmann, J.3    Bode-Böger, S.M.4    Frölich, J.C.5
  • 41
    • 0034716974 scopus 로고    scopus 로고
    • Assessment of nitric oxide synthase activity in vitro and in vivo by gas chromatography-mass spectrometry
    • 1:CAS:528:DC%2BD3cXksVGlu7k%3D
    • Tsikas D, Sandmann J, Savva A, Luessen P, Böger RH, Gutzki FM, Mayer B, Frölich JC (2000b) Assessment of nitric oxide synthase activity in vitro and in vivo by gas chromatography-mass spectrometry. J Chromatogr B 742:143-153
    • (2000) J Chromatogr B , vol.742 , pp. 143-153
    • Tsikas, D.1    Sandmann, J.2    Savva, A.3    Luessen, P.4    Böger, R.H.5    Gutzki, F.M.6    Mayer, B.7    Frölich, J.C.8
  • 42
    • 0141892585 scopus 로고    scopus 로고
    • Elevated plasma and urine levels of ADMA and 15(S)-8-iso-PGF2alpha in end-stage liver disease
    • 14512899
    • Tsikas D, Rode I, Becker T, Nashan B, Klempnauer J, Frölich JC (2003) Elevated plasma and urine levels of ADMA and 15(S)-8-iso-PGF2alpha in end-stage liver disease. Hepatology 38:1063-1064
    • (2003) Hepatology , vol.38 , pp. 1063-1064
    • Tsikas, D.1    Rode, I.2    Becker, T.3    Nashan, B.4    Klempnauer, J.5    Frölich, J.C.6
  • 43
    • 34248180612 scopus 로고    scopus 로고
    • Accurate quantification of dimethylamine (DMA) in human urine by gas chromatography-mass spectrometry as pentafluorobenzamide derivative: Evaluation of the relationship between DMA and its precursor asymmetric dimethylarginine (ADMA) in health and disease
    • 1:CAS:528:DC%2BD2sXlt1aktLk%3D
    • Tsikas D, Thum T, Becker T, Pham VV, Chobanyan K, Mitschke A, Beckmann B, Gutzki FM, Bauersachs J, Stichtenoth DO (2007) Accurate quantification of dimethylamine (DMA) in human urine by gas chromatography-mass spectrometry as pentafluorobenzamide derivative: evaluation of the relationship between DMA and its precursor asymmetric dimethylarginine (ADMA) in health and disease. J Chromatogr B 851:229-239
    • (2007) J Chromatogr B , vol.851 , pp. 229-239
    • Tsikas, D.1    Thum, T.2    Becker, T.3    Pham, V.V.4    Chobanyan, K.5    Mitschke, A.6    Beckmann, B.7    Gutzki, F.M.8    Bauersachs, J.9    Stichtenoth, D.O.10
  • 45
    • 84877579295 scopus 로고    scopus 로고
    • L-Homoarginine and l-arginine are antagonistically related to blood pressure in an elderly population: The Hoorn study
    • 23552121
    • van der Zwan LP, Davids M, Scheffer PG, Dekker JM, Stehouwer CD, Teerlink T (2013) l-Homoarginine and l-arginine are antagonistically related to blood pressure in an elderly population: the Hoorn study. J Hypertens 31:1114-1123
    • (2013) J Hypertens , vol.31 , pp. 1114-1123
    • Van Der Zwan, L.P.1    Davids, M.2    Scheffer, P.G.3    Dekker, J.M.4    Stehouwer, C.D.5    Teerlink, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.