Estimation of human age using N-glycan profiles from bloodstains

International Journal of Legal Medicine

Volumn 129, Issue 5, 2015, Pages 955-961

  Gudelj, Ivan ^a   Keser, Toma ^b   Vučković, Frano ^a   Škaro, Vedrana ^a   Goreta, Sandra Šupraha ^b   Pavić, Tamara ^b   Dumić, Jerka ^b   Primorac, Dragan ^a,c,d,e,f   Lauc, Gordan ^a,b   Gornik, Olga ^b  

^a GENOS GLYCOSCIENCE RESEARCH LABORATORY   (Croatia)

^b UNIVERSITY OF ZAGREB   (Croatia)

^c JOSIP JURAJ STROSSMAYER UNIVERSITY OF OSIJEK   (Croatia)

^d PENNSYLVANIA STATE UNIVERSITY   (United States)

^e UNIVERSITY OF SPLIT   (Croatia)

^f St Catherine Hospital   (Croatia)

Author keywords

Age estimation; Aging; Bloodstain; N glycosylation

Indexed keywords

POLYSACCHARIDE;

ADOLESCENT; ADULT; AGING; BLOOD; BLOOD STAIN; FEMALE; FORENSIC MEDICINE; GLYCOSYLATION; HUMAN; LIQUID CHROMATOGRAPHY; MALE; MIDDLE AGED; STATISTICAL MODEL; YOUNG ADULT;

ADOLESCENT; ADULT; AGING; BLOOD STAINS; CHROMATOGRAPHY, LIQUID; FEMALE; FORENSIC MEDICINE; GLYCOSYLATION; HUMANS; MALE; MIDDLE AGED; MODELS, STATISTICAL; POLYSACCHARIDES; YOUNG ADULT;

EID: 84940453389     PISSN: 09379827     EISSN: 14371596     Source Type: Journal    
DOI: 10.1007/s00414-015-1162-x     Document Type: Article

References (16)

1. Meissner C, Ritz-Timme S (2010) Molecular pathology and age estimation. Forensic Sci Int 203(1–3):34–43. doi:10.1016/j.forsciint.2010.07.010
2. Knežević A, Polašek O, Gornik O, Rudan I, Campbell H, Hayward C, Wright A, Kolčić I, O’Donoghue N, Bones J, Rudd PM, Lauc G (2009) Variability, heritability and environmental determinants of human plasma N-glycome. J Proteome Res 8:694–701
3. Pucic M, Knezevic A, Vidic J, Adamczyk B, Novokmet M, Polasek O, Gornik O, Supraha-Goreta S, Wormald MR, Redzic I, Campbell H, Wright A, Hastie ND, Wilson JF, Rudan I, Wuhrer M, Rudd PM, Josic D, Lauc G (2011) High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations. Mol Cell Proteomics 10(10):M111 010090. doi:10.1074/mcp.M111.010090
4. Knežević A, Gornik O, Polašek O, Pučić M, Novokmet M, Redžić I, Rudd PM, Wright AF, Campbell H, Rudan I, Lauc G (2010) Effects of aging, body mass index, plasma lipid profiles, and smoking on human plasma N-glycans. Glycobiology 20(8):959–969
5. Menni C, Keser T, Mangino M, Bell JT, Erte I, Akmacic I, Vuckovic F, Pucic Bakovic M, Gornik O, McCarthy MI, Zoldos V, Spector TD, Lauc G, Valdes AM (2013) Glycosylation of immunoglobulin g: role of genetic and epigenetic influences. PLoS One 8(12):e82558. doi:10.1371/journal.pone.0082558
6. Gornik O, Wagner J, Pučić M, Knežević A, Redžić I, Lauc G (2009) Stability of N-glycan profiles in human plasma. Glycobiology 19(12):1547–1553
7. Parekh R, Roitt I, Isenberg D, Dwek R, Rademacher T (1988) Age-related galactosylation of the N-linked oligosaccharides of human serum IgG. J Exp Med 167(5):1731–1736
8. Vanhooren V, Dewaele S, Libert C, Engelborghs S, De Deyn PP, Toussaint O, Debacq-Chainiaux F, Poulain M, Glupczynski Y, Franceschi C, Jaspers K, van der Pluijm I, Hoeijmakers J, Chen CC (2010) Serum N-glycan profile shift during human ageing. Exp Gerontol 45(10):738–743. doi:10.1016/j.exger.2010.08.009
9. Kristic J, Vuckovic F, Menni C, Klaric L, Keser T, Beceheli I, Pucic-Bakovic M, Novokmet M, Mangino M, Thaqi K, Rudan P, Novokmet N, Sarac J, Missoni S, Kolcic I, Polasek O, Rudan I, Campbell H, Hayward C, Aulchenko Y, Valdes A, Wilson JF, Gornik O, Primorac D, Zoldos V, Spector T, Lauc G (2014) Glycans are a novel biomarker of chronological and biological ages. J Gerontol A Biol Sci Med Sci 69(7):779–789. doi:10.1093/gerona/glt190
10. Parker SP, Cubitt WD (1999) The use of the dried blood spot sample in epidemiological studies. J Clin Pathol 52(9):633–639
11. Hewakapuge S, van Oorschot RA, Lewandowski P, Baindur-Hudson S (2008) Investigation of telomere lengths measurement by quantitative real-time PCR to predict age. Leg Med (Tokyo) 10(5):236–242. doi:10.1016/j.legalmed.2008.01.007
12. Epel ES, Blackburn EH, Lin J, Dhabhar FS, Adler NE, Morrow JD, Cawthon RM (2004) Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci U S A 101(49):17312–17315
13. Ou XL, Gao J, Wang H, Wang HS, Lu HL, Sun HY (2012) Predicting human age with bloodstains by sjTREC quantification. PLoS One 7(8):e42412. doi:10.1371/journal.pone.0042412
14. Tsuji A, Ishiko A, Takasaki T, Ikeda N (2002) Estimating age of humans based on telomere shortening. Forensic Sci Int 126(3):197–199
15. Gornik O, Lauc G (2008) Glycosylation of serum proteins in inflammatory diseases. Dis Markers 25(4–5):267–278
16. Huffman JE, Pucic-Bakovic M, Klaric L, Hennig R, Selman MH, Vuckovic F, Novokmet M, Kristic J, Borowiak M, Muth T, Polasek O, Razdorov G, Gornik O, Plomp R, Theodoratou E, Wright AF, Rudan I, Hayward C, Campbell H, Deelder AM, Reichl U, Aulchenko YS, Rapp E, Wuhrer M, Lauc G (2014) Comparative performance of four methods for high-throughput glycosylation analysis of immunoglobulin G in genetic and epidemiological research. Mol Cell Proteomics 13(6):1598–1610. doi:10.1074/mcp.M113.037465