The augmentation of O-GlcNAcylation reduces glyoxal-induced cell injury by attenuating oxidative stress in human retinal microvascular endothelial cells

International Journal of Molecular Medicine

Volumn 36, Issue 4, 2015, Pages 1019-1027

  Liu, Guo Dong ^a   Xu, Chong ^a,b   Feng, Le ^a   Wang, Fang ^a  

^a TENTH PEOPLE S HOSPITAL OF TONGJI UNIVERSITY   (China)

^b Nanshan Children and Women Healthcare Hospital   (China)

Author keywords

Diabetic retinopathy; Human retinal microvascular endothelial cells; O GlcNAcylation; Reactive oxygen species

Indexed keywords

CASPASE 3; GLUTATHIONE PEROXIDASE; GLYOXAL; N ACETYLGLUCOSAMINE; O LINKED BETA N ACETYL GLUCOSAMINE; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; ADVANCED GLYCATION END PRODUCT; HYDROGEN PEROXIDE;

APOPTOSIS; ARTICLE; CAPILLARY ENDOTHELIAL CELL; CELL DAMAGE; CELL VIABILITY; CONTROLLED STUDY; DIABETIC RETINOPATHY; DISEASE EXACERBATION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; RETINAL MICROVASCULAR ENDOTHELIAL CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ACYLATION; DRUG EFFECTS; ENDOTHELIUM CELL; METABOLISM; PATHOLOGY; RETINA;

ACYLATION; DIABETIC RETINOPATHY; ENDOTHELIAL CELLS; GLUTATHIONE PEROXIDASE; GLYCOSYLATION END PRODUCTS, ADVANCED; GLYOXAL; HUMANS; HYDROGEN PEROXIDE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RETINA; SUPEROXIDE DISMUTASE;

EID: 84940390369     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2015.2319     Document Type: Article

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