-
2
-
-
0027484673
-
Huntington's disease gene (IT15) is widely expressed in human and rat tissues
-
Li SH, Schilling G, Young WS, Li XJ, Margolis RL,et al. (1993) Huntington's disease gene (IT15) is widely expressed in human and rat tissues. Neuron 11: 985-993.
-
(1993)
Neuron
, vol.11
, pp. 985-993
-
-
Li, S.H.1
Schilling, G.2
Young, W.S.3
Li, X.J.4
Margolis, R.L.5
-
3
-
-
67650095269
-
Beyond the brain: widespread pathology in Huntington's disease
-
van der Burg JM, Björkqvist M, Brundin P (2009) Beyond the brain: widespread pathology in Huntington's disease. Lancet Neurol 8: 765-774.
-
(2009)
Lancet Neurol
, vol.8
, pp. 765-774
-
-
van der Burg, J.M.1
Björkqvist, M.2
Brundin, P.3
-
4
-
-
49249089029
-
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease
-
Björkqvist M, Wild EJ, Thiele J, Silvestroni A, Andre R,et al. (2008) A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease. J Exp Med 205: 1869-1877.
-
(2008)
J Exp Med
, vol.205
, pp. 1869-1877
-
-
Björkqvist, M.1
Wild, E.J.2
Thiele, J.3
Silvestroni, A.4
Andre, R.5
-
5
-
-
84867148826
-
Mutant huntingtin fragmentation in immune cells tracks Huntington's disease progression
-
Weiss A, Träger U, Wild EJ, Grueninger S, Farmer R,et al. (2012) Mutant huntingtin fragmentation in immune cells tracks Huntington's disease progression. J Clin Invest 122: 3731-3736.
-
(2012)
J Clin Invest
, vol.122
, pp. 3731-3736
-
-
Weiss, A.1
Träger, U.2
Wild, E.J.3
Grueninger, S.4
Farmer, R.5
-
6
-
-
0035111235
-
Early and progressive accumulation of reactive microglia in the Huntington disease brain
-
Sapp E, Kegel KB, Aronin N, Hashikawa T, Uchiyama Y,et al. (2001) Early and progressive accumulation of reactive microglia in the Huntington disease brain. J Neuropathol Exp Neurol 60: 161-172.
-
(2001)
J Neuropathol Exp Neurol
, vol.60
, pp. 161-172
-
-
Sapp, E.1
Kegel, K.B.2
Aronin, N.3
Hashikawa, T.4
Uchiyama, Y.5
-
7
-
-
34447636065
-
Microglial activation in presymptomatic Huntington's disease gene carriers
-
Tai YF, Pavese N, Gerhard A, Tabrizi SJ, Barker RA,et al. (2007) Microglial activation in presymptomatic Huntington's disease gene carriers. Brain 130: 1759-1766.
-
(2007)
Brain
, vol.130
, pp. 1759-1766
-
-
Tai, Y.F.1
Pavese, N.2
Gerhard, A.3
Tabrizi, S.J.4
Barker, R.A.5
-
8
-
-
34547167008
-
Proteomic profiling of plasma in Huntington's disease reveals neuroinflammatory activation and biomarker candidates
-
Dalrymple A, Wild EJ, Joubert R, Sathasivam K, Björkqvist M,et al. (2007) Proteomic profiling of plasma in Huntington's disease reveals neuroinflammatory activation and biomarker candidates. J Proteome Res 6: 2833-2840.
-
(2007)
J Proteome Res
, vol.6
, pp. 2833-2840
-
-
Dalrymple, A.1
Wild, E.J.2
Joubert, R.3
Sathasivam, K.4
Björkqvist, M.5
-
9
-
-
84855975733
-
Abnormal peripheral chemokine profile in Huntington's disease
-
Wild E, Magnusson A, Lahiri N, Krus U, Orth M,et al. (2011) Abnormal peripheral chemokine profile in Huntington's disease. PLoS Curr 3: RRN1231.
-
(2011)
PLoS Curr
, vol.3
-
-
Wild, E.1
Magnusson, A.2
Lahiri, N.3
Krus, U.4
Orth, M.5
-
10
-
-
84940222913
-
HTT-lowering reverses Huntington's disease immune dysfunction caused by NFκB-pathway dysregulation
-
in press
-
Träger U, Andre R, Lahiri N, Magnusson-Lind A, Weiss A,et al. (2013) HTT-lowering reverses Huntington's disease immune dysfunction caused by NFκB-pathway dysregulation. Brain in press.
-
(2013)
Brain
-
-
Träger, U.1
Andre, R.2
Lahiri, N.3
Magnusson-Lind, A.4
Weiss, A.5
-
11
-
-
34547108380
-
JAK-STAT signaling: from interferons to cytokines
-
Schindler C, Levy DE, Decker T (2007) JAK-STAT signaling: from interferons to cytokines. J Biol Chem 282: 20059-20063.
-
(2007)
J Biol Chem
, vol.282
, pp. 20059-20063
-
-
Schindler, C.1
Levy, D.E.2
Decker, T.3
-
12
-
-
0242468041
-
Regulation of JAK-STAT signalling in the immune system
-
Shuai K, Liu B (2003) Regulation of JAK-STAT signalling in the immune system. Nat Rev Immunol 3: 900-911.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 900-911
-
-
Shuai, K.1
Liu, B.2
-
13
-
-
0036731485
-
Stats: transcriptional control and biological impact
-
Levy DE, Darnell JE (2002) Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol 3: 651-662.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 651-662
-
-
Levy, D.E.1
Darnell, J.E.2
-
14
-
-
0041677606
-
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
-
Heinrich PC, Behrmann I, Haan S, Hermanns HM, Müller-Newen G,et al. (2003) Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem J 374: 1-20.
-
(2003)
Biochem J
, vol.374
, pp. 1-20
-
-
Heinrich, P.C.1
Behrmann, I.2
Haan, S.3
Hermanns, H.M.4
Müller-Newen, G.5
-
15
-
-
0032168152
-
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
-
Heinrich PC, Behrmann I, Müller-Newen G, Schaper F, Graeve L (1998) Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem J 334 (Pt 2): 297-314.
-
(1998)
Biochem J
, vol.334
, Issue.Pt 2
, pp. 297-314
-
-
Heinrich, P.C.1
Behrmann, I.2
Müller-Newen, G.3
Schaper, F.4
Graeve, L.5
-
16
-
-
85009332113
-
Unified Huntington's Disease Rating Scale: reliability and consistency. Huntington Study Group
-
Huntington Study Group
-
Huntington Study Group (1996) Unified Huntington's Disease Rating Scale: reliability and consistency. Huntington Study Group. Mov Disord 11: 136-142.
-
(1996)
Mov Disord
, vol.11
, pp. 136-142
-
-
-
17
-
-
0019444436
-
Huntington disease: functional capacities in patients treated with neuroleptic and antidepressant drugs
-
Shoulson I (1981) Huntington disease: functional capacities in patients treated with neuroleptic and antidepressant drugs. Neurology 31: 1333-1335.
-
(1981)
Neurology
, vol.31
, pp. 1333-1335
-
-
Shoulson, I.1
-
18
-
-
3242683662
-
Single cell profiling of potentiated phospho-protein networks in cancer cells
-
Irish JM, Hovland R, Krutzik PO, Perez OD, Bruserud Ø,et al. (2004) Single cell profiling of potentiated phospho-protein networks in cancer cells. Cell 118: 217-228.
-
(2004)
Cell
, vol.118
, pp. 217-228
-
-
Irish, J.M.1
Hovland, R.2
Krutzik, P.O.3
Perez, O.D.4
Bruserud, Ø.5
-
19
-
-
38349043669
-
High-content single-cell drug screening with phosphospecific flow cytometry
-
Krutzik PO, Crane JM, Clutter MR, Nolan GP (2008) High-content single-cell drug screening with phosphospecific flow cytometry. Nat Chem Biol 4: 132-142.
-
(2008)
Nat Chem Biol
, vol.4
, pp. 132-142
-
-
Krutzik, P.O.1
Crane, J.M.2
Clutter, M.R.3
Nolan, G.P.4
-
20
-
-
0036173143
-
Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry
-
Perez OD, Nolan GP (2002) Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry. Nat Biotechnol 20: 155-162.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 155-162
-
-
Perez, O.D.1
Nolan, G.P.2
-
21
-
-
0035478329
-
STAT5 induces macrophage differentiation of M1 leukemia cells through activation of IL-6 production mediated by NF-kappaB p65
-
Kawashima T, Murata K, Akira S, Tonozuka Y, Minoshima Y,et al. (2001) STAT5 induces macrophage differentiation of M1 leukemia cells through activation of IL-6 production mediated by NF-kappaB p65. J Immunol 167: 3652-3660.
-
(2001)
J Immunol
, vol.167
, pp. 3652-3660
-
-
Kawashima, T.1
Murata, K.2
Akira, S.3
Tonozuka, Y.4
Minoshima, Y.5
-
22
-
-
4644307407
-
Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity
-
Khoshnan A, Ko J, Watkin EE, Paige LA, Reinhart PH,et al. (2004) Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity. J Neurosci 24: 7999-8008.
-
(2004)
J Neurosci
, vol.24
, pp. 7999-8008
-
-
Khoshnan, A.1
Ko, J.2
Watkin, E.E.3
Paige, L.A.4
Reinhart, P.H.5
-
23
-
-
79958191139
-
The role of IκB kinase complex in the neurobiology of Huntington's disease
-
Khoshnan A, Patterson PH (2011) The role of IκB kinase complex in the neurobiology of Huntington's disease. Neurobiol Dis 43: 305-311.
-
(2011)
Neurobiol Dis
, vol.43
, pp. 305-311
-
-
Khoshnan, A.1
Patterson, P.H.2
|