Quantitation of thiol metabolites from mammalian cells using fluorous tagging and HILIC-MS

Analytical Methods

Volumn 7, Issue 17, 2015, Pages 7164-7169

  Esch, Caroline ^a   Hui, Dawn S ^b,c   Lee, Richard ^b,c   Edwards, James L ^a  

^a Saint Louis University   (United States)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SAINT LOUIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETONITRILE; COVALENT BONDS; ENDOTHELIAL CELLS; MAMMALS; METABOLISM; SULFUR COMPOUNDS;

AMMONIUM FORMATE; BIOLOGICAL SAMPLES; EQUILIBRIUM SHIFT; LABELING STRATEGY; LINEAR GRADIENTS; METABOLIC PATHWAYS; SIGNAL INTENSITIES; THERAPEUTIC TARGETS;

METABOLITES;

EID: 84940194491     PISSN: 17599660     EISSN: 17599679     Source Type: Journal    
DOI: 10.1039/c5ay00603a     Document Type: Article

References (17)

1. A. A. Rasmiena T. W. Ng P. J. Meikle Metabolomics and ischaemic heart disease Clin. Sci. 2013 124 5 289 306
2. I. D. Federation, Diabetes Atlas, 6th edn, 2013
3. M. Brownlee Biochemistry and molecular cell biology of diabetic complications Nature 2001 414 6865 813 820
4. R. L. Thomas F. D. Dunstan S. D. Luzio S. R. Chowdhury R. V. North S. L. Hale R. L. Gibbins D. R. Owens Prevalence of diabetic retinopathy within a national diabetic retinopathy screening service Br. J. Ophthalmol. 2015 99 1 64 68
5. H. Rosolova B. Petrlova J. Simon P. Sifalda I. Sipova F. Sefrna Macrovascular and microvascular complications in type 2 diabetes patients Vnitr. Lek. 2008 54 3 229 237
6. G. M. Leinninger J. L. Edwards M. J. Lipshaw E. L. Feldman Mechanisms of disease: mitochondria as new therapeutic targets in diabetic neuropathy Nat. Clin. Pract. Neurol. 2006 2 11 620 628
7. A. A. Little J. L. Edwards E. L. Feldman Diabetic neuropathies Practical Neurol. 2007 7 2 82 92
8. A. M. Vincent J. L. Edwards M. Sadidi E. L. Feldman The antioxidant response as a drug target in diabetic neuropathy Curr. Drug Targets 2008 9 1 94 100
9. F. Giacco M. Brownlee Oxidative stress and diabetic complications Circ. Res. 2010 107 9 1058 1070
10. S. Borra D. E. Featherstone S. A. Shippy Total cysteine and glutathione determination in hemolymph of individual adult D. melanogaster Anal. Chim. Acta 2015 853 660 667
11. M. E. McMenamin J. Himmelfarb T. D. Nolin Simultaneous analysis of multiple aminothiols in human plasma by high performance liquid chromatography with fluorescence detection J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. 2009 877 28 3274 3281
12. W. Yuan J. L. Edwards Thiol metabolomics of endothelial cells using capillary liquid chromatography mass spectrometry with isotope coded affinity tags J. Chromatogr. A 2011 1218 18 2561 2568
13. R. E. Hansen J. R. Winther An introduction to methods for analyzing thiols and disulfides: Reactions, reagents, and practical considerations Anal. Biochem. 2009 394 2 147 158
14. B. Seiwert U. Karst Simultaneous LC/MS/MS determination of thiols and disulfides in urine samples based on differential labeling with ferrocene-based maleimides Anal. Chem. 2007 79 18 7131 7138
15. L. A. D'Agostino K. P. Lam R. Lee P. Britz-McKibbin Comprehensive plasma thiol redox status determination for metabolomics J. Proteome Res. 2011 10 2 592 603
16. N. B. Cech C. G. Enke Practical implications of some recent studies in electrospray ionization fundamentals Mass Spectrom. Rev. 2001 20 6 362 387
17. W. Yuan J. L. Edwards Thiol metabolomics of endothelial cells using capillary liquid chromatography mass spectrometry with isotope coded affinity tags J. Chromatogr. A 2011 1218 18 2561 2568