Design and optimization of SiON ring resonator-based biosensors for aflatoxin M1 detection

Sensors (Switzerland)

Volumn 15, Issue 7, 2015, Pages 17300-17312

  Guider, Romain ^a   Gandolfi, Davide ^a   Chalyan, Tatevik ^a   Pasquardini, Laura ^b   Samusenko, Alina ^a,b   Pucker, Georg ^b   Pederzolli, Cecilia ^b   Pavesi, Lorenzo ^a  

^a UNIVERSITY OF TRENTO   (Italy)

^b FONDAZIONE BRUNO KESSLER   (Italy)

Author keywords

Aflatoxin; Biosensor; Label free; Limit of detection; Ring resonator; Sensitivity; Waveguide; Whispering gallery mode

Indexed keywords

AFLATOXINS; BIOSENSORS; COST EFFECTIVENESS; OPTICAL RESONATORS; RESONATORS; SILICON NITRIDE; WAVEGUIDES; WHISPERING GALLERY MODES;

BIOSENSING APPLICATIONS; DESIGN AND OPTIMIZATION; LABEL FREE; LIMIT OF DETECTION; REFRACTIVE INDEX CHANGES; REFRACTIVE INDEX UNITS; RING RESONATOR; SENSITIVITY;

REFRACTIVE INDEX;

AFLATOXIN M1; SILICON DERIVATIVE;

CHEMISTRY; DEVICES; EQUIPMENT DESIGN; GENETIC PROCEDURES; LIGHT RELATED PHENOMENA; LIMIT OF DETECTION; MAGNETISM;

AFLATOXIN M1; BIOSENSING TECHNIQUES; EQUIPMENT DESIGN; LIMIT OF DETECTION; MAGNETIC PHENOMENA; OPTICAL PHENOMENA; SILICON COMPOUNDS;

EID: 84940190960     PISSN: 14248220     EISSN: None     Source Type: Journal    
DOI: 10.3390/s150717300     Document Type: Article

References (15)

1. Ciminelli, C.; Campanella, C.M.; Dell’Olio, F.; Campanella, C.E.; Armenise, M.N. Label-free optical resonant sensors for biochemical applications. Prog. Quantum Electron. 2013, 37, 51–107.
2. Vollmer, F.; Yang, L. Label-free detection with high-Q microcavities: A review of biosensing mechanisms for integrated devices. Nanophotonics 2012, 1, 267–291.
3. Bogaerts, W.; de Heyn, P.; van Vaerenbergh, T.; de Vos, K.; Kumar Selvaraja, S.; Claes, T.; Dumon, P.; Bienstman, P.; van Tourhout, D.; Baets, R. Silicon microring resonators. Laser Photonics Rev. 2012, 6, 47–73.
4. Iqbal, M.; Gleeson, M.A.; Spaugh, B.; Tybor, F.; Gunn, W.G.; Hochberg, M.; Baehr-Jones, T.; Bailey, R.C.; Gunn, L.C. Label-free biosensor arrays based on silicon ring resonators and high-speed optical scanning instrumentation. IEEE J. Sel. Top. Quantum Electron. 2010, 16, 654–661.
5. Symphony Project Official Website. Available online: http://www.symphony-project.eu/ (accessed on 31 May 2015).
6. COMSOL Multiphysics Modeling Software. Available online: http://www.comsol.com (accessed on 31 May 2015).
7. Mancinelli, M. Linear and Nonlinear Coupling Effects in Sequence of Microresonators. Ph.D. Thesis, University of Trento, Trento, Italy, 2013.
8. Cheema, M.I.; Kirk, A.G. Accurate determination of the quality factor and tunneling distance of axisymmetric resonators for biosensing applications. Opt. Express 2013, 21, 8724–8735.
9. Gandolfi, D.; Ramiro-Manzano, F.; Aparicio Rebollo, F.J.; Ghulinyan, M.; Pucker, G.; Pavesi, L. Role of edge inclination in an optical microdisk resonator for label-free sensing. Sensors 2015, 15, 4796–4809.
10. Guider, R.; Daldosso, N.; Pitanti, A.; Jordana, E.; Fedeli, J.-M.; Pavesi, L. Nano Si low loss horizontal slot waveguides coupled to high Q ring resonators. Opt. Express 2009, 17, 20762–20770.
11. Wörhoff, K.; Klein, E.; Hussein, G.; Driessen, A. Silicon oxynitride based photonics. In Proceedings of the 2008 10th Anniversary International Conference on Transparent Optical Networks, Athens, Greece, 22–26 June 2008.
12. Yariv, A. Universal relations for coupling of optical power between microresonators and dielectric waveguides. Electron. Lett. 2000, 36, 321–322.
13. Gandolfi, D.; Guider, R.; Chalyan, T.; Pavesi, L.; Pasquardini, L.; Pederzolli, C.; Samusenko, A.; Pucker, G. Sensitivity and limit of detection of biosensors based on ring resonators. In Proceedings of the AISEM Annual Conference 2015 XVIII, Trento, Italy, 3–5 February 2015.
14. Song, S.; Wang, L.; Li, J.; Zhao, J.; Fan, C. Aptamer-based biosensors. Trends Anal. Chem. 2008, 27, 108–117.
15. Palchetti, I.; Mascini, M. Electrochemical nanomaterial-based nucleic acid aptasensors. Anal. Bioanal. Chem. 2012, 402, 3103–3114.