Plant uptake of pharmaceutical and personal care products from recycled water and biosolids: A review

Science of the Total Environment

Volumn 536, Issue , 2015, Pages 655-666

  Wu, Xiaoqin ^a   Dodgen, Laurel K ^a   Conkle, Jeremy L ^a   Gan, Jay ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Biosolids; Health risks; Plant uptake; PPCPs; Reclamation; Treated wastewater

Indexed keywords

AGRICULTURE; ARID REGIONS; BIOLOGICAL MATERIALS; BIOSOLIDS; CROPS; HEALTH RISKS; IRRIGATION; LAND RECLAMATION; SOILS; WASTEWATER TREATMENT; WATER TREATMENT;

AGRICULTURAL IRRIGATION; ARID AND SEMI-ARID REGIONS; CONCENTRATION LEVELS; EMERGING CONTAMINANT; PHARMACEUTICAL AND PERSONAL CARE PRODUCTS; PLANT UPTAKE; PPCPS; TREATED WASTEWATER;

WASTEWATER RECLAMATION;

CHEMICAL COMPOUND; PHARMACEUTICAL AND PERSONAL CARE PRODUCT; UNCLASSIFIED DRUG; COSMETIC; DRUG; SOIL POLLUTANT; WASTE WATER;

BIOLOGICAL UPTAKE; BIOSOLID; CROP PLANT; DRUG; HEALTH RISK; RECYCLING; WASTEWATER; WATER TREATMENT;

BIOACCUMULATION; BIOAVAILABILITY; BIODEGRADATION; BIOSOLID; CHEMICAL PARAMETERS; CHEMICAL PROCEDURES; CHEMICAL TRANSLOCATION; CLEANUP; CONCENTRATION (PARAMETERS); DIETARY INTAKE; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL IMPACT; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HYDROPHOBICITY; HYDROPONICS; IRRIGATION (AGRICULTURE); LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MASS FRAGMENTOGRAPHY; NONHUMAN; PLANT METABOLISM; PLANT PARAMETERS; PLANT UPTAKE; POLLUTION TRANSPORT; PRIORITY JOURNAL; REVIEW; ROOT UPTAKE; SOIL; SOIL AMENDMENT; WASTE WATER RECYCLING; AGRICULTURE; ANALYSIS; CHEMISTRY; ENVIRONMENTAL MONITORING; PROCEDURES; SEWAGE; SOIL POLLUTANT; WASTE WATER;

AGRICULTURAL IRRIGATION; AGRICULTURE; COSMETICS; ENVIRONMENTAL MONITORING; PHARMACEUTICAL PREPARATIONS; SOIL POLLUTANTS; WASTE DISPOSAL, FLUID; WASTE WATER;

EID: 84940048637     PISSN: 00489697     EISSN: 18791026     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2015.07.129     Document Type: Review

References (106)

1. Aryal N., Reinhold D.M. Phytoaccumulation of antimicrobials from biosolids: impacts on environmental fate and relevance to human exposure. Water Res. 2011, 45:5545-5552.
2. Arye G., Dror I., Berkowitz B. Fate and transport of carbamazepine in soil aquifer treatment (SAT) infiltration basin soils. Chemosphere 2011, 82:244-252.
3. Avisar D., Lester Y., Ronen D. Sulfamethoxazole contamination of a deep phreatic aquifer. Sci. Total Environ. 2009, 407:4278-4282.
4. Bahlmann A., Brack W., Schneider R.J., Krauss M. Carbamazepine and its metabolites in wastewater: analytical pitfalls and occurrence in Germany and Portugal. Water Res. 2014, 57:104-114.
5. Bartha B., Huber C., Harpaintner R., Schroeder P. Effects of acetaminophen in Brassica juncea L. Czern.: investigation of uptake, translocation, detoxification, and the induced defense pathways. Environ. Sci. Pollut. Res. 2010, 17:1553-1562.
6. Bennett G.D., Amore B.M., Finnell R.H., Wlodarczyk B., Kalhorn T.F., Skiles G.L., Nelson S.D., Slattery J.T. Teratogenicity of carbamazepine-10,11-epoxide and oxcarbazepine in the SWV mouse. J. Pharmacol. Exp. Ther. 1996, 279:1237-1242.
7. Bondarenko S., Gan J., Ernst F., Green R., Baird J., McCullough M. Leaching of pharmaceuticals and personal care products in turfgrass soils during recycled water irrigation. J. Environ. Qual. 2012, 41:1268-1274.
8. Borgman O., Chefetz B. Combined effects of biosolids application and irrigation with reclaimed wastewater on transport of pharmaceutical compounds in arable soils. Water Res. 2013, 47:3431-3443.
9. Boxall A.B.A., Johnson P., Smith E.J., Sinclair C.J., Stutt E., Levy L.S. Uptake of veterinary medicines from soils into plants. J. Agric. Food Chem. 2006, 54:2288-2297.
10. Briggs G.G., Bromilow R.H., Evans A.A. Relationships between lipophilicity and root uptake and translocation of non-ionized chemicals by barley. Pestic. Sci. 1982, 13:495-504.
11. Briggs G.G., Rigitano R.L.O., Bromilow R.H. Physicochemical factors affecting uptake by roots and translocation to shoots of weak acids in barley. Pestic. Sci. 1987, 19:101-112.
12. Brodin T., Fick J., Jonsson M., Klaminder J. Dilute concentrations of a psychiatric drug alter behavior of fish from natural populations. Science 2013, 339:814-815.
13. Calderón-Preciado D., Jiménez-Cartagena C., Peñuela G., Bayona J.M. Development of an analytical procedure for the determination of emerging and priority organic pollutants in leafy vegetables by pressurized solvent extraction followed by GC-MS determination. Anal. Bioanal. Chem. 2009, 394:1319-1327.
14. Calderón-Preciado D., Jiménez-Cartagena C., Matamoros V., Bayona J.M. Screening of 47 organic microcontaminants in agricultural irrigation waters and their soil loading. Water Res. 2011, 45:221-231.
15. Calderón-Preciado D., Renault Q., Matamoros V., Cañameras N., Bayona J.M. Uptake of organic emergent contaminants in spath and lettuce: an in vitro experiment. J. Agric. Food Chem. 2012, 60:2000-2007.
16. Carter L.J., Harris E., Williams M., Ryan J.J., Kookana R.S., Boxall A.B.A. Fate and uptake of pharmaceuticals in soil-plant systems. J. Agric. Food Chem. 2014, 62:816-825.
17. Carvalho P.N., Basto M.C.P., Almeida C.M.R., Brix H. A review of plant-pharmaceutical interactions: from uptake and effects in crop plants to phytoremediation in constructed wetlands. Environ. Sci. Pollut. Res. 2014, 10.1007/s11356-014-2550-3.
18. Chefetz B., Mualem T., Ben-Ari J. Sorption and mobility of pharmaceutical compounds in soil irrigated with reclaimed wastewater. Chemosphere 2008, 73:1335-1343.
19. Clarke B.O., Smith S.R. Review of 'emerging' organic contaminants in biosolids and assessment of international research priorities for the agricultural use of biosolids. Environ. Int. 2011, 37:226-247.
20. Conners D.E., Rogers E.D., Armbrust K.L., Kwon J.-W., Black M.C. Growth and development of tadpoles (Xenopus laevis) exposed to selective serotonin reuptake inhibitors, fluoxetine and sertraline, throughout metamorphosis. Environ. Toxicol. Chem. 2009, 28:2671-2676.
21. Cortés J.M., Larsson E., Jönsson J.A. Study of the uptake of non-steroid anti-inflammatory drugs in wheat and soybean after application of sewage sludge as a fertilizer. Sci. Total Environ. 2013, 449:385-389.
22. Das B., Lee L., Rao P., Hultgren R. Sorption and degradation of steroid hormones in soils during transport: column studies and model evaluation. Environ. Sci. Technol. 2004, 38:1460-1470.
23. Dodgen L.K., Li J., Parker D., Gan J.J. Uptake and accumulation of four PPCP/EDCs in two leafy vegetables. Environ. Pollut. 2013, 182:150-156.
24. Dodgen L.K., Li J., Wu X., Lu Z., Gan J.J. Transformation and removal pathways of four common PPCP/EDCs in soil. Environ. Pollut. 2014, 193:29-36.
25. Dodgen L.K., Ueda A., Wu X., Parker D.R., Gan J. Effect of transpiration on plant accumulation and translocation of PPCP/EDCs. Environ. Pollut. 2015, 198:144-153.
26. Dolliver H., Kumar K., Gupta S. Sulfamethazine uptake by plants from manure-amended soil. J. Environ. Qual. 2007, 36:1224-1230.
27. Dordio A.V., Belo M., Martins Teixeira D., Palace Carvalho A.J., Dias C.M.B., Pico Y., Pinto A.P. Evaluation of carbamazepine uptake and metabolization by Typha spp., a plant with potential use in phytotreatment. Bioresour. Technol. 2011, 102:7827-7834.
28. Eggen T., Asp T.N., Grave K., Hormazabal V. Uptake and translocation of metformin, ciprofloxacin and narasin in forage- and crop plants. Chemosphere 2011, 85:26-33.
29. Gibson R., Duran-Alvarez J.C., Leon Estrada K., Chavez A., Jimenez Cisneros B. Accumulation and leaching potential of some pharmaceuticals and potential endocrine disruptors in soils irrigated with wastewater in the Tula Valley, Mexico. Chemosphere 2010, 81:1437-1445.
30. Goldstein M., Shenker M., Chefetz B. Insights into the uptake processes of wastewater-borne pharmaceuticals by vegetables. Environ. Sci. Technol. 2014, 48:5593-5600.
31. Gottschall N., Topp E., Metcalfe C., Edwards M., Payne M., Kleywegt S., Russell P., Lapen D.R. Pharmaceutical and personal care products in groundwater, subsurface drainage, soil, and wheat grain, following a high single application of municipal biosolids to a field. Chemosphere 2012, 87:194-203.
32. Grossberger A., Hadar Y., Borch T., Chefetz B. Biodegradability of pharmaceutical compounds in agricultural soils irrigated with treated wastewater. Environ. Pollut. 2014, 185:168-177.
33. Haham H., Oren A., Chefetz B. Insight into the role of dissolved organic matter in sorption of sulfapyridine by semiarid soils. Environ. Sci. Technol. 2012, 46:11870-11877.
34. Hazelton P.D., Cope W.G., Mosher S., Pandolfo T.J., Belden J.B., Barnhart M.C., Bringolf R.B. Fluoxetine alters adult freshwater mussel behavior and larval metamorphosis. Sci. Total Environ. 2013, 445:94-100.
35. Herklotz P.A., Gurung P., Heuvel B.V., Kinney C.A. Uptake of human pharmaceuticals by plants grown under hydroponic conditions. Chemosphere 2010, 78:1416-1421.
36. Holling C.S., Bailey J.L., Heuvel B.V., Kinney C.A. Uptake of human pharmaceuticals and personal care products by cabbage (Brassica campestris) from fortified and biosolids-amended soils. J. Environ. Monitor. 2012, 14:3029-3036.
37. Hu X., Zhou Q., Luo Y. Occurrence and source analysis of typical veterinary antibiotics in manure, soil, vegetables and groundwater from organic vegetable bases, northern China. Environ. Pollut. 2010, 158:2992-2998.
38. Huber C., Bartha B., Harpaintner R., Schroeder P. Metabolism of acetaminophen (paracetamol) in plants - two independent pathways result in the formation of a glutathione and a glucose conjugate. Environ. Sci. Pollut. Res. 2009, 16:206-213.
39. Huber C., Bartha B., Schroeder P. Metabolism of diclofenac in plants - hydroxylation is followed by glucose conjugation. J. Hazard. Mater. 2012, 243:250-256.
40. Inoue J., Chamberlain K., Bromilow R.H. Physicochemical factors affecting the uptake by roots and translocation to shoots of amine bases in barley. Pestic. Sci. 1998, 54:8-21.
41. Jones-Lepp T.L., Sanchez C.A., Moy T., Kazemi R. Method development and application to determine potential plant uptake of antibiotics and other drugs in irrigated crop production systems. J. Agric. Food Chem. 2010, 58:11568-11573.
42. Kawabata K., Sugihara K., Sanoh S., Kitamura S., Ohta S. Photodegradation of pharmaceuticals in the aquatic environment by sunlight and UV-A, -B and -C irradiation. J. Toxicol. Sci. 2013, 38:215-223.
43. Kim S.D., Cho J., Kim I.S., Vanderford B.J., Snyder S.A. Occurrence and removal of pharmaceuticals and endocrine disruptors in South Korean surface, drinking, and waste waters. Water Res. 2007, 41:1013-1021.
44. Kinney C.A., Furlong E.T., Zaugg S.D., Burkhardt M.R., Werner S.L., Cahill J.D., Jorgensen G.R. Survey of organic wastewater contaminants in biosolids destined for land application. Environ. Sci. Technol. 2006, 40:7207-7215.
45. Kinney C.A., Furlong E.T., Werner S.L., Cahill J.D. Presence and distribution of wastewater-derived pharmaceuticals in soil irrigated with reclaimed water. Environ. Toxicol. Chem. 2006, 25:317-326.
46. Kolb M., Harms H. Metabolism of fluoranthene in different plant cell cultures and intact plants. Environ. Toxicol. Chem. 2000, 19:1304-1310.
47. Kumar K., Gupta S.C., Baidoo S.K., Chander Y., Rosen C.J. Antibiotic uptake by plants from soil fertilized with animal manure. J. Environ. Qual. 2005, 34:2082-2085.
48. Li J., Dodgen L., Ye Q., Gan J. Degradation kinetics and metabolites of carbamazepine in soil. Environ. Sci. Technol. 2013, 47:3678-3684.
49. Li J., Ye Q., Gan J. Degradation and transformation products of acetaminophen in soil. Water Res. 2014, 49:44-52.
50. Lin K., Gan J. Sorption and degradation of wastewater associated non-steroidal anti-inflammatory drugs and antibiotics in soils. Chemosphere 2011, 83:240-246.
51. Llewellyn N., Lloyd P., Jurgens M.D., Johnson A.C. Determination of cyclophosphamide and ifosfamide in sewage effluent by stable isotope-dilution liquid chromatography -tandem mass spectrometry. J. Chromatogr. A 2011, 1218:8519-8528.
52. Macherius A., Eggen T., Lorenz W., Moeder M., Ondruschka J., Reemtsma T. Metabolization of the bacteriostatic agent triclosan in edible plants and its consequences for plant uptake assessment. Environ. Sci. Technol. 2012, 46:10797-10804.
53. Malchi T., Maor Y., Tadmor G., Shenker M., Chefetz B. Irrigation of root vegetables with treated wastewater: evaluating uptake of pharmaceuticals and the associated human health risks. Environ. Sci. Technol. 2014, 48:9325-9333.
54. Malchi T., Maor Y., Chefetz B. Comments on "Human health risk assessment of pharmaceuticals and personal care products in plant tissue due to biosolids and manure amendments, and wastewater irrigation". Environ. Int. 2015, 82:110-112.
55. Marsoni M., De Mattia F., Labra M., Bruno A., Bracale M., Vannini C. Uptake and effects of a mixture of widely used therapeutic drugs in Eruca sativa L. and Zea mays L. plants. Ecotoxicol. Environ. Saf. 2014, 108:52-57.
56. Matamoros V., Calderón-Preciado D., Dominguez C., Bayona J.M. Analytical procedures for the determination of emerging organic contaminants in plant material: A review. Anal. Chim. Acta 2012, 722:8-20.
57. McClellan K., Halden R.U. Pharmaceuticals and personal care products in archived US biosolids from the 2001 EPA national sewage sludge survey. Water Res. 2010, 44:658-668.
58. Miao X.S., Yang J.J., Metcalfe C.D. Carbamazepine and its metabolites in wastewater and in biosolids in a municipal wastewater treatment plant. Environ. Sci. Technol. 2005, 39:7469-7475.
59. Migliore L., Cozzolino S., Fiori M. Phytotoxicity to and uptake of enrofloxacin in crop plants. Chemosphere 2003, 52:1233-1244.
60. Mitchell S.M., Ullman J.L., Teel A.L., Watts R.J. pH and temperature effects on the hydrolysis of three β-lactam antibiotics: ampicillin, cefalotin and cefoxitin. Sci. Total Environ. 2014, 466-467:547-555.
61. Monteiro S.C., Boxall A.B.A. Factors affecting the degradation of pharmaceuticals in agricultural soils. Environ. Toxicol. Chem. 2009, 28:2546-2554.
62. Navon R., Hernandez-Ruiz S., Chorover J., Chefetz B. Interactions of carbamazepine in soil: effects of dissolved organic matter. J. Environ. Qual. 2011, 40:942-948.
63. Pan M., Wong C.K., Chu L.M. Distribution of antibiotics in wastewater-irrigated soils and their accumulation in vegetable crops in the Pearl River Delta, southern China. J. Agric. Food Chem. 2014, 62:11062-11069.
64. Pannu M.W., Toor G.S., O'Connor G.A., Wilson P.C. Toxicity and bioaccumulation of biosolids-borne triclosan in food crops. Environ. Toxicol. Chem. 2012, 31:2130-2137.
65. Podlipna R., Skalova L., Seidlova H., Szotakova B., Kubicek V., Stuchlikova L., Jirasko R., Vanek T., Vokral I. Biotransformation of benzimidazole anthelmintics in reed (Phragmites australis) as a potential tool for their detoxification in environment. Bioresour. Technol. 2013, 144:216-224.
66. Prosser R.S., Sibley P.K. Human health risk assessment of pharmaceuticals and personal care products in plant tissue due to biosolids and manure amendments, and wastewater irrigation. Environ. Int. 2015, 75:223-233.
67. Prosser R.S., Lissemore L., Topp E., Sibley P.K. Bioaccumulation of triclosan and triclocarban in plants grown in soils amended with municipal dewatered biosolids. Environ. Toxicol. Chem. 2014, 33:975-984.
68. Prosser R.S., Trapp S., Sibley P.K. Modeling uptake of selected pharmaceuticals and personal care products into food crops from biosolids-amended soil. Environ. Sci. Technol. 2014, 48:11397-11404.
69. Redshaw C.H., Wootton V.G., Rowland S.J. Uptake of the pharmaceutical fluoxetine hydrochloride from growth medium by Brassicaceae. Phytochemistry 2008, 69:2510-2516.
70. Ruiz S.H., Wickramasekara S., Abrell L., Gao X., Chefetz B., Chorover J. Complexation of trace organic contaminants with fractionated dissolved organic matter: implications for mass spectrometric quantification. Chemosphere 2013, 91:344-350.
71. Sabourin L., Duenk P., Bonte-Gelok S., Payne M., Lapen D.R., Topp E. Uptake of pharmaceuticals, hormones and parabens into vegetables grown in soil fertilized with municipal biosolids. Sci. Total Environ. 2012, 431:233-236.
72. SCCWRP (Southern California Coastal Water Research Project) Monitoring strategies for Chemicals of Emerging Concern (CECs) in California's aquatic ecosystems 2012, (Costa Mesa, California).
73. Schopfer P., Brennicke A. Pflanzenphysiologie 1999, Springer, Berlin. 5th ed.
74. Schultz M.M., Painter M.M., Bartell S.E., Logue A., Furlong E.T., Werner S.L., Schoenfuss H.L. Selective uptake and biological consequences of environmentally relevant antidepressant pharmaceutical exposures on male fathead minnows. Aquat. Toxicol. 2011, 104:38-47.
75. Semple K.T., Doick K.J., Jones K.C., Burauel P., Craven A., Harms H. Defining bioavailability and bioaccessibility of contaminated soil and sediment is complicated. Environ. Sci. Technol. 2004, 38:228A-231A.
76. Shenker M., Harush D., Ben-Ari J., Chefetz B. Uptake of carbamazepine by cucumber plants - a case study related to irrigation with reclaimed wastewater. Chemosphere 2011, 82:905-910.
77. Snyder S.A., Leising J., Westerhoff P., Yoon Y., Mash H., Vanderford B. Biological and physical attenuation of endocrine disruptors and pharmaceuticals: implications for water reuse. Ground Water Monit. Remediat. 2004, 24:108-118.
78. Sui Q., Huang J., Deng S., Chen W., Yu G. Seasonal variation in the occurrence and removal of pharmaceuticals and personal care products in different biological wastewater treatment processes. Environ. Sci. Technol. 2011, 45:3341-3348.
79. Tanoue R., Sato Y., Motoyama M., Nakagawa S., Shinohara R., Nomiyama K. Plant uptake of pharmaceutical chemicals detected in recycled organic manure and reclaimed wastewater. J. Agric. Food Chem. 2012, 60:10203-10211.
80. Ternes T.A., Joss A., Siegrist H. Scrutinizing pharmaceuticals and personal care products in wastewater treatment. Environ. Sci. Technol. 2004, 38:392A-399A.
81. Tolls J. Sorption of veterinary pharmaceuticals in soils: a review. Environ. Sci. Technol. 2001, 35:3397-3406.
82. Topp E., Hendel J.G., Lapen D.R., Chapman R. Fate of the nonsteroidal antiinflammatory drug naproxen in agricultural soil receiving liquid municipal biosolids. Environ. Toxicol. Chem. 2008, 27:2005-2010.
83. Trapp S. Modelling uptake into roots and subsequent translocation of neutral and ionisable organic compounds. Pest Manag. Sci. 2000, 56:767-778.
84. Trapp S. Bioaccumulation of polar and ionizable compounds in plants 2009, 299-353.
85. U.S.EPA Biosolids generation, use, and disposal in the United States 1999, Washington, D.C.
86. U.S.EPA Biosolids technology fact sheet: land application of biosolids 2000, Washington, D.C.
87. U.S.EPA Targeted national sewage sludge survey 2009, Washington, D.C.
88. U.S.EPA Available at. http://water.epa.gov/polwaste/wastewater/treatment/biosolids/genqa.cfm.
89. Van Eerd L.L., Hoagland R.E., Zablotowicz R.M., Hall J.C. Pesticide metabolism in plants and microorganisms. Weed Sci. 2003, 51:472-495.
90. Vanderford B., Snyder S. Analysis of pharmaceuticals in water by isotope dilution liquid chromatography/tandem mass spectrometry. Environ. Sci. Technol. 2006, 40:7312-7320.
91. Walters E., McClellan K., Halden R.U. Occurrence and loss over three years of 72 pharmaceuticals and personal care products from biosolids-soil mixtures in outdoor mesocosms. Water Res. 2010, 44:6011-6020.
92. Water Authority, State of Israel Long-term master plan for the national water sector, part A - policy document (Version 4) 2012.
93. WHO Health guidelines for the use of wastewater in agriculture and aquaculture 1989, World Health Organization (WHO), Geneva.
94. Williams C.F., Williams C.F., Adamsen F.J. Sorption-desorption of carbamazepine from irrigated soils. J. Environ. Qual. 2006, 35:1779-1783.
95. Winker M., Clemens J., Reich M., Gulyas H., Otterpohl R. Ryegrass uptake of carbamazepine and ibuprofen applied by urine fertilization. Sci. Total Environ. 2010, 408:1902-1908.
96. Wu C., Spongberg A.L., Witter J.D., Fang M., Czajkowski K.P. Uptake of pharmaceutical and personal care products by soybean plants from soils applied with biosolids and irrigated with contaminated water. Environ. Sci. Technol. 2010, 44:6157-6161.
97. Wu C., Spongberg A.L., Witter J.D. The uptake of pharmaceuticals and personal care products by agriculturally relevant plant species. Chim. Oggi 2011, 29:54-56.
98. Wu X., Conkle J.L., Gan J. Multi-residue determination of pharmaceutical and personal care products in vegetables. J. Chromatogr. A 2012, 1254:78-86.
99. Wu C., Spongberg A.L., Witter J.D., Sridhar B.B.M. Transfer of wastewater associated pharmaceuticals and personal care products to crop plants from biosolids treated soil. Ecotoxicol. Environ. Saf. 2012, 85:104-109.
100. Wu X., Ernst F., Conkle J.L., Gan J. Comparative uptake and translocation of pharmaceutical and personal care products (PPCPs) by common vegetables. Environ. Int. 2013, 60:15-22.
101. Wu X., Conkle J.L., Ernst F., Gan J. Treated wastewater irrigation: uptake of pharmaceutical and personal care products by common vegetables under field conditions. Environ. Sci. Technol. 2014, 48:11286-11293.
102. Xia K., Hundal L.S., Kumar K., Armbrust K., Cox A.E., Granato T.C. Triclocarban, triclosan, polybrominated diphenyl ethers, and 4-nonylphenol in biosolids and in soil receiving 33-year biosolids application. Environ. Toxicol. Chem. 2010, 29:597-605.
103. Xu J., Wu L., Chang A.C. Degradation and adsorption of selected pharmaceuticals and personal care products (PPCPs) in agricultural soils. Chemosphere 2009, 77:1299-1305.
104. Ying G.G., Yu X.Y., Kookana R.S. Biological degradation of triclocarban and triclosan in a soil under aerobic and anaerobic conditions and comparison with environmental fate modelling. Environ. Pollut. 2007, 150:300-305.
105. Yu Y., Liu Y., Wu L. Sorption and degradation of pharmaceuticals and personal care products (PPCPs) in soils. Environ. Sci. Pollut. Res. Int. 2013, 20:4261-4267.
106. Zarate F.M., Schulwitz S.E., Stevens K.J., Venables B.J. Bioconcentration of triclosan, methyl-triclosan, and triclocarban in the plants and sediments of a constructed wetland. Chemosphere 2012, 88:323-329.