Ginsenoside Compound K suppresses the hepatic gluconeogenesis via activating adenosine-5′monophosphate kinase: A study in vitro and in vivo

Life Sciences

Volumn 139, Issue , 2015, Pages 8-15

  Wei, Shengnan ^a   Li, Wei ^b   Yu, Yang ^a   Yao, Fan ^a   A, Lixiang ^a   Lan, Xiaoxin ^a   Guan, Fengying ^a   Zhang, Ming ^a   Chen, Li ^a  

^a JILIN UNIVERSITY   (China)

^b JILIN AGRICULTURAL UNIVERSITY   (China)

Author keywords

AMP activated protein kinase; Compound K; Ginseng; Hepatic gluconeogenesis; Type 2 diabetes

Indexed keywords

ADENOSINE KINASE; COMPOUND K; GINSENOSIDE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); STREPTOZOCIN; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG; ANTIDIABETIC AGENT; GINSENOSIDE M1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPID DIET; LIVER CELL; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; CHEMISTRY; DIABETES MELLITUS, TYPE 2; DRUG EFFECTS; ENZYMOLOGY; LIVER; METABOLISM; PANAX;

MUS; PANAX GINSENG;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; DIABETES MELLITUS, TYPE 2; ENZYME ACTIVATION; GINSENOSIDES; GLUCONEOGENESIS; GLUCOSE; GLUCOSE-6-PHOSPHATASE; HEP G2 CELLS; HEPATOCYTES; HUMANS; HYPOGLYCEMIC AGENTS; LIVER; MALE; MICE; PANAX; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS;

EID: 84940027280     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2015.07.032     Document Type: Article

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