Response to endovascular reperfusion is not time-dependent in patients with salvageable tissue

Neurology

Volumn 85, Issue 8, 2015, Pages 708-714

  Lansberg, Maarten G ^a   Cereda, Carlo W ^a,b   Mlynash, Michael ^a   Mishra, Nishant K ^a   Inoue, Manabu ^a   Kemp, Stephanie ^a   Christensen, Søren ^a   Straka, Matus ^a   Zaharchuk, Greg ^a   Marks, Michael P ^a   Bammer, Roland ^a   Albers, Gregory W ^a  

^a STANFORD UNIVERSITY   (United States)

^b Neurocentre (EOC) of Southern Switzerland   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTICLE; CEREBROVASCULAR ACCIDENT; COHORT ANALYSIS; DIFFUSION WEIGHTED IMAGING; ENDOVASCULAR SURGERY; FEMALE; HUMAN; MAGNETIC RESONANCE PERFUSION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROSPECTIVE STUDY; RADIATION ATTENUATION; RANKIN SCALE; REPERFUSION; STROKE PATIENT; TIME TO TREATMENT; BRAIN CIRCULATION; FOLLOW UP; MIDDLE AGED; OUTCOME ASSESSMENT; PATHOLOGY; PHYSIOLOGY; STANDARDS; STROKE; TIME; VERY ELDERLY;

AGED; AGED, 80 AND OVER; CEREBROVASCULAR CIRCULATION; ENDOVASCULAR PROCEDURES; FEMALE; FOLLOW-UP STUDIES; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OUTCOME ASSESSMENT (HEALTH CARE); REPERFUSION; STROKE; TIME FACTORS;

EID: 84940026172     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0000000000001853     Document Type: Article

References (23)

1. Campbell BCV, Mitchell PJ, Kleinig TJ, et al; EXTENDIA Investigators. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 2015; 372:1009-1018.
2. Goyal M, Demchuk AM, Menon BK, et al; ESCAPE Trial Investigators. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 2015; 372:1019-1030.
3. Berkhemer OA, Fransen PSS, Beumer D, et al; MR CLEAN Investigators. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 2015; 372:11-20.
4. Saver J. Solitaire FR with the intention for thrombectomy as primary endovascular treatment for acute ischemic stroke: preliminary results. Presented at the International Stroke Conference; February 11, 2015; Nashville, TN.
5. Khatri P, Abruzzo T, Yeatts SD, Nichols C, Broderick JP, Tomsick TA; IMS I and II Investigators. Good clinical outcome after ischemic stroke with successful revascularization is time-dependent. Neurology 2009;73:1066-1072.
6. Khatri P, Yeatts SD, Mazighi M, et al; IMS III Trialists. Time to angiographic reperfusion and clinical outcome after acute ischaemic stroke: an analysis of data from the Interventional Management of Stroke (IMS III) phase 3 trial. Lancet Neurol 2014;13:567-574.
7. Baron JC, von Kummer R, del Zoppo GJ. Treatment of acute ischemic stroke. Challenging the concept of a rigid and universal time window. Stroke 1995;26:2219-2221.
8. Gonzalez RG, Hakimelahi R, Schaefer PW, Roccatagliata L, Sorensen AG, Singhal AB. Stability of large diffusion/perfusion mismatch in anterior circulation strokes for 4 or more hours. BMC Neurol 2010;10:10-13.
9. Hakimelahi R, González RG. Neuroimaging of ischemic stroke with CT and MRI: advancing towards physiologybased diagnosis and therapy. Expert Rev Cardiovasc Ther 2009;7:29-48.
10. Hakimelahi R, Vachha BA, Copen WA, et al. Time and diffusion lesion size in major anterior circulation ischemic strokes. Stroke 2014;45:2936-2941.
11. Marchal G, Beaudouin V, Rioux P, et al. Prolonged persistence of substantial volumes of potentially viable brain tissue after stroke: a correlative PET-CT study with voxelbased data analysis. Stroke 1996;27:599-606.
12. Baron JC, Macrae IM, Adams HP Jr, Dirnagl U. ESCBRAIN: experimental and clinical stroke research-do they connect? Meeting report of the ESC-BRAIN joint symposium held in London and Shanghai in May 2013 Cerebrovasc Dis 2013;36:306-321.
13. Davis S, Campbell B, Christensen S, et al. Perfusion/Diffusion mismatch is valid and should be used for selecting delayed interventions. Transl Stroke Res 2012;3:188-197.
14. Donnan GA, Baron JC, Ma H, Davis SM. Penumbral selection of patients for trials of acute stroke therapy. Lancet Neurol 2009;8:261-269.
15. Fisher M, Albers GW. Advanced imaging to extend the therapeutic time window of acute ischemic stroke. Ann Neurol 2013;73:4-9.
16. Lansberg MG, Straka M, Kemp S, et al; DEFUSE 2 study investigators. MRI profile and response to endovascular reperfusion after stroke (DEFUSE 2): a prospective cohort study. Lancet Neurol 2012;11:860-867.
17. Straka M, Albers GW, Bammer R. Real-time diffusionperfusion mismatch analysis in acute stroke. J Magn Reson Imaging 2010;32:1024-1037.
18. Higashida RT, Furlan AJ, Roberts H, et al. Trial design and reporting standards for intra-arterial cerebral thrombolysis for acute ischemic stroke. Stroke 2003;34:e109-e137.
19. Albers GW. Endovascular treatment for stroke: when does the window for good outcome close? Lancet Neurol 2014; 13:529-531.
20. Kidwell CS, Jahan R, Gornbein J, et al; MR RESCUE Investigators. A trial of imaging selection and endovascular treatment for ischemic stroke. N Engl J Med 2013;368:914-923.
21. Marks MP, Lansberg MG, Mlynash M, et al; DEFUSE Investigators. Angiographic outcome of endovascular stroke therapy correlated with MR findings, infarct growth, and clinical outcome in the DEFUSE 2 trial. Int J Stroke 2014;9:860-865.
22. Picanço MR, Christensen S, Campbell BCV, et al. Reperfusion after 4.5 hours reduces infarct growth and improves clinical outcomes. Int J Stroke 2014;9:266-269.
23. Leiva-Salinas C, Aghaebrahim A, Zhu G, et al. Tissue at risk in acute stroke patients treated beyond 8 h after symptom onset. Neuroradiology 2013;55:807-812.