-
1
-
-
84888627079
-
Etiology and therapeutic approach to elevated lactate levels
-
1 Andersen LW, Mackenhauer J, Roberts JC, Berg KM, Cocchi MN, Donnino MW. Etiology and therapeutic approach to elevated lactate levels. Mayo Clin Proc 2013;88(10):1127-40.
-
(2013)
Mayo Clin Proc
, vol.88
, Issue.10
, pp. 1127-1140
-
-
Ersen, L.W.1
Mackenhauer, J.2
Roberts, J.C.3
Berg, K.M.4
Cocchi, M.N.5
Donnino, M.W.6
-
2
-
-
84863693768
-
Trial failure prompts soul-searching for critical-care specialists
-
Dolgin E. Trial failure prompts soul-searching for critical-care specialists. Nat Med 2012;18(7):1000.
-
(2012)
Nat Med
, vol.18
, Issue.7
, pp. 1000
-
-
Dolgin, E.1
-
3
-
-
84897377065
-
Why have clinical trials in sepsis failed?
-
Marshall JC. Why have clinical trials in sepsis failed? Trends Mol Med 2014;20(4):195-203.
-
(2014)
Trends Mol Med
, vol.20
, Issue.4
, pp. 195-203
-
-
Marshall, J.C.1
-
4
-
-
36448948021
-
Transcutaneous vagus nerve stimulation reduces serum high mobility group box 1 levels and improves survival in murine sepsis
-
Huston JM, Gallowitsch-Puerta M, Ochani M, Ochani K, Yuan R, Rosas-Ballina M, et al. Transcutaneous vagus nerve stimulation reduces serum high mobility group box 1 levels and improves survival in murine sepsis. Crit Care Med 2007;35(12): 2762-8.
-
(2007)
Crit Care Med
, vol.35
, Issue.12
, pp. 2762-2768
-
-
Huston, J.M.1
Gallowitsch-Puerta, M.2
Ochani, M.3
Ochani, K.4
Yuan, R.5
Rosas-Ballina, M.6
-
5
-
-
84895144365
-
Central cholinergic activation of a vagus nerve-to-spleen circuit alleviates experimental colitis
-
Ji H, Rabbi MF, Labis B, Pavlov VA, Tracey KJ, Ghia JE. Central cholinergic activation of a vagus nerve-to-spleen circuit alleviates experimental colitis. Mucosal Immunol 2014;7(2): 335-47.
-
(2014)
Mucosal Immunol
, vol.7
, Issue.2
, pp. 335-347
-
-
Ji, H.1
Rabbi, M.F.2
Labis, B.3
Pavlov, V.A.4
Tracey, K.J.5
Ghia, J.E.6
-
6
-
-
84925879871
-
Vagus nerve stimulation: A new bioelectronics approach to treat rheumatoid arthritis?
-
Koopman FA, Schuurman PR, Vervoordeldonk MJ, Tak PP. Vagus nerve stimulation: a new bioelectronics approach to treat rheumatoid arthritis? Best Pract Res Clin Rheumatol 2014; 28(4):625-35.
-
(2014)
Best Pract Res Clin Rheumatol
, vol.28
, Issue.4
, pp. 625-635
-
-
Koopman, F.A.1
Schuurman, P.R.2
Vervoordeldonk, M.J.3
Tak, P.P.4
-
8
-
-
0033902012
-
Hypoxia-induced vascular endothelial growth factor expression precedes neovascularization after cerebral ischemia
-
Marti HJ, Bernaudin M, Bellail A, Schoch H, Euler M, Petit E, et al. Hypoxia-induced vascular endothelial growth factor expression precedes neovascularization after cerebral ischemia. Am J Pathol 2000;156(3):965-76.
-
(2000)
Am J Pathol
, vol.156
, Issue.3
, pp. 965-976
-
-
Marti, H.J.1
Bernaudin, M.2
Bellail, A.3
Schoch, H.4
Euler, M.5
Petit, E.6
-
9
-
-
0025649045
-
Role of erythro-poietin in adaptation to hypoxia
-
Scholz H, Schurek HJ, Eckardt KU, Bauer C. Role of erythro-poietin in adaptation to hypoxia. Experientia 1990;46(11-12): 1197-201.
-
(1990)
Experientia
, vol.46
, Issue.11-12
, pp. 1197-1201
-
-
Scholz, H.1
Schurek, H.J.2
Eckardt, K.U.3
Bauer, C.4
-
10
-
-
84940084457
-
Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum
-
Staudacher JJ, Naarmann-de Vries IS, Ujvari SJ, Klinger B, Kasim M, Benko E, et al. Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum. Nucleic Acids Res 2015. doi: 10.1093/nar/gkv167.
-
(2015)
Nucleic Acids Res
-
-
Staudacher, J.J.1
Naarmann-De Vries, I.S.2
Ujvari, S.J.3
Klinger, B.4
Kasim, M.5
Benko, E.6
-
11
-
-
24344443670
-
Hypoxia-dependent activation of HIF into a transcriptional regulator
-
Ruas JL, Poellinger L. Hypoxia-dependent activation of HIF into a transcriptional regulator. Semin Cell Dev Biol 2005; 16(4-5):514-22.
-
(2005)
Semin Cell Dev Biol
, vol.16
, Issue.4-5
, pp. 514-522
-
-
Ruas, J.L.1
Poellinger, L.2
-
12
-
-
0034682786
-
Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: A mechanism of O2 sensing
-
Chandel NS, McClintock DS, Feliciano CE, Wood TM, Melendez JA, Rodriguez AM, et al. Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing. J Biol Chem 2000;275(33):25130-8.
-
(2000)
J Biol Chem
, vol.275
, Issue.33
, pp. 25130-25138
-
-
Chandel, N.S.1
McClintock, D.S.2
Feliciano, C.E.3
Wood, T.M.4
Melendez, J.A.5
Rodriguez, A.M.6
-
14
-
-
33747596652
-
Oxygen sensing by mitochondria at complex III: The paradox of increased reactive oxygen species during hypoxia
-
Guzy RD, Schumacker PT. Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia. Exp Physiol 2006;91(5):807-19.
-
(2006)
Exp Physiol
, vol.91
, Issue.5
, pp. 807-819
-
-
Guzy, R.D.1
Schumacker, P.T.2
-
16
-
-
84896671549
-
Immunological characterization of compensatory anti-inflammatory response syndrome in patients with severe sepsis: A longitudinal study*
-
Gomez HG, Gonzalez SM, Londono JM, Hoyos NA, Nino CD, Leon AL, et al. Immunological characterization of compensatory anti-inflammatory response syndrome in patients with severe sepsis: a longitudinal study*. Crit Care Med 2014;42(4):771-80.
-
(2014)
Crit Care Med
, vol.42
, Issue.4
, pp. 771-780
-
-
Gomez, H.G.1
Gonzalez, S.M.2
Londono, J.M.3
Hoyos, N.A.4
Nino, C.D.5
Leon, A.L.6
-
17
-
-
0033969341
-
Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: A marker for prognosis and future therapeutic options
-
Gogos CA, Drosou E, Bassaris HP, Skoutelis A. Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: a marker for prognosis and future therapeutic options. J Infect Dis 2000;181(1):176-80.
-
(2000)
J Infect Dis
, vol.181
, Issue.1
, pp. 176-180
-
-
Gogos, C.A.1
Drosou, E.2
Bassaris, H.P.3
Skoutelis, A.4
-
18
-
-
0032770268
-
Mitochondrial redox state in the critically ill
-
Yassen KA, Galley HF, Lee A, Webster NR. Mitochondrial redox state in the critically ill. Br J Anaesth 1999;83(2):325-7.
-
(1999)
Br J Anaesth
, vol.83
, Issue.2
, pp. 325-327
-
-
Yassen, K.A.1
Galley, H.F.2
Lee, A.3
Webster, N.R.4
-
19
-
-
3142716777
-
Mitochondrial dysfunction in sepsis
-
Brealey D, Singer M. Mitochondrial dysfunction in sepsis. Curr Infect Dis Rep 2003;5(5):365-71.
-
(2003)
Curr Infect Dis Rep
, vol.5
, Issue.5
, pp. 365-371
-
-
Brealey, D.1
Singer, M.2
-
20
-
-
0037142987
-
Association between mitochondrial dysfunction and severity and outcome of septic shock
-
Brealey D, Brand M, Hargreaves I, Heales S, Land J, Smolenski R, et al. Association between mitochondrial dysfunction and severity and outcome of septic shock. Lancet 2002;360(9328): 219-23.
-
(2002)
Lancet
, vol.360
, Issue.9328
, pp. 219-223
-
-
Brealey, D.1
Brand, M.2
Hargreaves, I.3
Heales, S.4
Land, J.5
Smolenski, R.6
-
21
-
-
4444273012
-
Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: Effect on survival in patients with septic shock
-
Lopez A, Lorente JA, Steingrub J, Bakker J, McLuckie A, Willatts S, et al. Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: effect on survival in patients with septic shock. Crit Care Med 2004;32(1):21-30.
-
(2004)
Crit Care Med
, vol.32
, Issue.1
, pp. 21-30
-
-
Lopez, A.1
Lorente, J.A.2
Steingrub, J.3
Bakker, J.4
McLuckie, A.5
Willatts, S.6
-
22
-
-
77955958738
-
Effects of a selective iNOS inhibitor versus norepinephrine in the treatment of septic shock
-
Su F, Huang H, Akieda K, Occhipinti G, Donadello K, Piagnerelli M, et al. Effects of a selective iNOS inhibitor versus norepinephrine in the treatment of septic shock. Shock 2010;34(3):243-9.
-
(2010)
Shock
, vol.34
, Issue.3
, pp. 243-249
-
-
Su, F.1
Huang, H.2
Akieda, K.3
Occhipinti, G.4
Donadello, K.5
Piagnerelli, M.6
-
23
-
-
84911466192
-
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
-
Chouchani ET, Pell VR, Gaude E, Aksentijevic D, Sundier S. Y, Robb EL, et al. Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS. Nature 2014; 515(7527):431-5.
-
(2014)
Nature
, vol.515
, Issue.7527
, pp. 431-435
-
-
Chouchani, E.T.1
Pell, V.R.2
Gaude, E.3
Aksentijevic, D.4
Sundier, S.Y.5
Robb, E.L.6
-
24
-
-
0023359298
-
Pathogenesis and management of septic shock
-
Luce JM. Pathogenesis and management of septic shock. Chest 1987;91(6):883-8.
-
(1987)
Chest
, vol.91
, Issue.6
, pp. 883-888
-
-
Luce, J.M.1
-
25
-
-
84876285741
-
Succinate is an inflammatory signal that induces IL-1beta through HIF-1alpha
-
Tannahill GM, Curtis AM, Adamik J, Palsson-McDermott EM, McGettrick AF, Goel G, et al. Succinate is an inflammatory signal that induces IL-1beta through HIF-1alpha. Nature 2013; 496(7444):238-42.
-
(2013)
Nature
, vol.496
, Issue.7444
, pp. 238-242
-
-
Tannahill, G.M.1
Curtis, A.M.2
Adamik, J.3
Palsson-McDermott, E.M.4
McGettrick, A.F.5
Goel, G.6
-
26
-
-
80054678294
-
Bench-to-bedside review: Sepsis - From the redox point of view
-
Andrades ME, Morina A, Spasic S, Spasojevic I. Bench-to-bedside review: sepsis - from the redox point of view. Crit Care 2011;15(5):230.
-
(2011)
Crit Care
, vol.15
, Issue.5
, pp. 230
-
-
Andrades, M.E.1
Morina, A.2
Spasic, S.3
Spasojevic, I.4
-
27
-
-
84866919941
-
Selection, synthesis, and anti-inflammatory evaluation of the arylidene malonate derivatives as TLR4 signaling inhibitors
-
Zhang S, Cheng K, Wang X, Yin H. Selection, synthesis, and anti-inflammatory evaluation of the arylidene malonate derivatives as TLR4 signaling inhibitors. Bioorg Med Chem 2012; 20(20):6073-9.
-
(2012)
Bioorg Med Chem
, vol.20
, Issue.20
, pp. 6073-6079
-
-
Zhang, S.1
Cheng, K.2
Wang, X.3
Yin, H.4
-
28
-
-
77955283395
-
Animal and human studies with the mitochondria-targeted antioxidant MitoQ
-
Smith RA, Murphy MP. Animal and human studies with the mitochondria-targeted antioxidant MitoQ. Ann N Y Acad Sci 2010;1201:96-103.
-
(2010)
Ann N Y Acad Sci
, vol.1201
, pp. 96-103
-
-
Smith, R.A.1
Murphy, M.P.2
-
29
-
-
79959412738
-
Oxidative stress and mitochondrial dysfunction in sepsis
-
Galley HF. Oxidative stress and mitochondrial dysfunction in sepsis. Br J Anaesth 2011;107(1):57-64.
-
(2011)
Br J Anaesth
, vol.107
, Issue.1
, pp. 57-64
-
-
Galley, H.F.1
|