Impact on prognosis of the regional distribution of MGMT methylation with respect to the CpG island methylator phenotype and age in glioma patients

Journal of Neuro-Oncology

Volumn 122, Issue 3, 2015, Pages 441-450

  Mur, Pilar ^a   Rodríguez de Lope, Ángel ^a   Díaz Crespo, Francisco Javier ^a   Hernández Iglesias, Teresa ^a   Ribalta, Teresa ^b   Fiaño, Concepción ^c   García, Juan Fernando ^d   Rey, Juan Antonio ^e   Mollejo, Manuela ^a   Meléndez, Bárbara ^a  

^a HOSPITAL VIRGEN DE LA SALUD   (Spain)

^b HOSPITAL CLÍNIC   (Spain)

^c UNIVERSITY HOSPITAL COMPLEX OF VIGO   (Spain)

^d MD ANDERSON CANCER CENTER   (Spain)

^e HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

Author keywords

CpG island methylator phenotype; Glioma; IDH mutation; MGMT methylation; Overall survival

Indexed keywords

DNA LIGASE; DNA METHYLTRANSFERASE; MGMT PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

ADULT; AGE; AGED; BRAIN NEOPLASMS; CPG ISLAND; DNA METHYLATION; DNA MICROARRAY; FEMALE; GENE EXPRESSION PROFILING; GENETICS; GLIOMA; HUMAN; MALE; MIDDLE AGED; MORTALITY; PHENOTYPE; PRINCIPAL COMPONENT ANALYSIS; PROGNOSIS; PROMOTER REGION; SURVIVAL ANALYSIS; YOUNG ADULT;

ADULT; AGE FACTORS; AGED; BRAIN NEOPLASMS; CPG ISLANDS; DNA METHYLATION; DNA MODIFICATION METHYLASES; DNA REPAIR ENZYMES; FEMALE; GENE EXPRESSION PROFILING; GLIOMA; HUMANS; MALE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; PRINCIPAL COMPONENT ANALYSIS; PROGNOSIS; PROMOTER REGIONS, GENETIC; SURVIVAL ANALYSIS; TUMOR SUPPRESSOR PROTEINS; YOUNG ADULT;

EID: 84939996462     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-015-1738-9     Document Type: Article

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