High glucose enhances store-operated calcium entry by upregulating ORAI/STIM via calcineurin-NFAT signalling

Journal of Molecular Medicine

Volumn 93, Issue 5, 2015, Pages 511-521

  Daskoulidou, Nikoleta ^a   Zeng, Bo ^a   Berglund, Lisa M ^b   Jiang, Hongni ^a   Chen, Gui Lan ^a   Kotova, Olga ^b   Bhandari, Sunil ^c   Ayoola, James ^a   Griffin, Steven ^d   Atkin, Stephen L ^e   Gomez, Maria F ^b   Xu, Shang Zhong ^a  

^a UNIVERSITY OF HULL   (United Kingdom)

^b LUND UNIVERSITY   (Sweden)

^c HULL ROYAL INFIRMARY   (United Kingdom)

^d CASTLE HILL HOSPITAL   (United Kingdom)

^e WEILL CORNELL MEDICAL COLLEGE   (Qatar)

Author keywords

Calcineurin; Calcium channels; Diabetes mellitus; Hyperglycaemia; NFATc transcription factors; ORAI; STIM1

Indexed keywords

CALCINEURIN; CALCIUM; CALCIUM CHANNEL; GLUCOSE; MESSENGER RNA; TRANSCRIPTION FACTOR NFAT;

ANIMAL; CELL LINE; DISEASE MODEL; ENDOTHELIUM CELL; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MALE; METABOLISM; MIDDLE AGED; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; UPREGULATION;

ANIMALS; CALCINEURIN; CALCIUM; CALCIUM CHANNELS; CELL LINE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; GLUCOSE; HUMANS; MALE; MICE; MICE, TRANSGENIC; MIDDLE AGED; NFATC TRANSCRIPTION FACTORS; RNA, MESSENGER; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84939980055     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-014-1234-2     Document Type: Article

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