Interleukin-2 receptor β Thr-450 phosphorylation is a positive regulator for receptor complex stability and activation of signaling molecules

Journal of Biological Chemistry

Volumn 290, Issue 34, 2015, Pages 20972-20983

  Ruiz Medina, Blanca E ^a   Ross, Jeremy A ^a   Kirken, Robert A ^a  

^a UNIVERSITY OF TEXAS AT EL PASO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CHEMICAL ACTIVATION; PROTEINS;

FUNCTIONAL CHARACTERIZATION; NATURAL KILLER CELLS; PHOSPHORYLATION SITES; PHOSPHOSPECIFIC ANTIBODIES; RECONSTITUTION ASSAY; SIGNALING MOLECULES; TRANSCRIPTIONALLY ACTIVE; TYROSINE PHOSPHORYLATION;

PHOSPHORYLATION;

INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR BETA; JAK3 PROTEIN, HUMAN; JANUS KINASE 3; MAPK1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOPROTEIN PHOSPHATASE 1; PROTEIN KINASE B; SERINE; SMALL INTERFERING RNA; STAT5 PROTEIN; THREONINE; TYROSINE;

AMINO ACID SEQUENCE; ANTAGONISTS AND INHIBITORS; CELL LINE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; CELL LINE; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-2; INTERLEUKIN-2 RECEPTOR BETA SUBUNIT; JANUS KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN PHOSPHATASE 1; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; SERINE; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; THREONINE; TYROSINE;

EID: 84939825235     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.660654     Document Type: Article

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