Fibrin-genipin annulus fibrosus sealant as a delivery system for anti-TNFα drug

Spine Journal

Volumn 15, Issue 9, 2015, Pages 2045-2054

  Likhitpanichkul, Morakot ^a,b   Kim, Yesul ^a   Torre, Olivia M ^a   See, Eugene ^c   Kazezian, Zepur ^b,c   Pandit, Abhay ^b,c   Hecht, Andrew C ^a   Iatridis, James C ^a,b  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b AO FOUNDATION   (Switzerland)

^c NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

Annulus fibrosus repair; Anti inflammatory drug; Biomaterials; Drug delivery; Intervertebral disc; Spinal injection

Indexed keywords

COLLAGEN TYPE 1; FIBRIN; GENIPIN; INFLIXIMAB; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; NANOSPHERE; TUMOR NECROSIS FACTOR ALPHA; ANTIRHEUMATIC AGENT; DRUG CARRIER; FIBRIN GLUE; IRIDOID;

ANNULUS FIBROSUS; ARTICLE; BIOLOGICAL ACTIVITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CROSS LINKING; CYTOKINE PRODUCTION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; ENZYMATIC DEGRADATION; FEASIBILITY STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SEALANT; SUSTAINED DRUG RELEASE; CELL CULTURE; CHEMISTRY; DRUG EFFECTS; INTERVERTEBRAL DISK;

ANTIRHEUMATIC AGENTS; CELLS, CULTURED; DRUG CARRIERS; FIBRIN TISSUE ADHESIVE; HUMANS; INFLIXIMAB; INTERVERTEBRAL DISC; IRIDOIDS;

EID: 84939820938     PISSN: 15299430     EISSN: 18781632     Source Type: Journal    
DOI: 10.1016/j.spinee.2015.04.026     Document Type: Article

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