Structural Basis for Enhancement of Carbapenemase Activity in the OXA-51 Family of Class D β-Lactamases

ACS Chemical Biology

Volumn 10, Issue 8, 2015, Pages 1791-1796

  Smith, Clyde A ^a   Antunes, Nuno Tiago ^b   Stewart, Nichole K ^b   Frase, Hilary ^b   Toth, Marta ^b   Kantardjieff, Katherine A ^c   Vakulenko, Sergei ^b  

^a SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

^b UNIVERSITY OF NOTRE DAME   (United States)

^c CALIFORNIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE; BETA LACTAMASE OXA 15; CARBAPENEM; CARBAPENEMASE; DORIPENEM; ERTAPENEM; IMIPENEM; MEROPENEM; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; BETA-LACTAMASE OXA-51, ACINETOBACTER BAUMANNII;

ACINETOBACTER BAUMANNII; AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL CELL; CATALYSIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME STRUCTURE; GENE DOSAGE; HYDROGEN BOND; HYDROLYSIS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; STEADY STATE; STEREOSPECIFICITY; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; KINETICS; METABOLISM; MOLECULAR MODEL; PROTEIN CONFORMATION;

ACINETOBACTER BAUMANNII;

ACINETOBACTER BAUMANNII; BACTERIAL PROTEINS; BETA-LACTAMASES; CATALYTIC DOMAIN; KINETICS; MODELS, MOLECULAR; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY;

EID: 84939795270     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/acschembio.5b00090     Document Type: Article

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