MicroRNA expression profile and the role of miR-204 in corneal wound healing

Investigative Ophthalmology and Visual Science

Volumn 56, Issue 6, 2015, Pages 3673-3683

  An, Jianhong ^a,b   Chen, Xiaoyan ^a,b   Chen, Weiwei ^a,b   Liang, Rongxin ^a,b   Reinach, Peter S ^a,b   Yan, Dongsheng ^a,b   Tu, LiLi ^a,b  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b State Key Laboratory Cultivation Base and Key Laboratory of Vision Science Ministry of Health of the People’s Republic of China Zhejiang Provincial Key Laboratory of Ophthalmology and Optometry ^*  (China)

Author keywords

Corneal wound healing; Migration; miR 204; miRNA profile; Proliferation

Indexed keywords

MICRORNA; MICRORNA 106A; MICRORNA 1224; MICRORNA 125B 5P; MICRORNA 142 3P; MICRORNA 148A; MICRORNA 154; MICRORNA 181A; MICRORNA 184; MICRORNA 1983; MICRORNA 19A; MICRORNA 19B; MICRORNA 200A; MICRORNA 200B; MICRORNA 203; MICRORNA 204; MICRORNA 20A; MICRORNA 24; MICRORNA 26B; MICRORNA 30B; MICRORNA 30C; MICRORNA 30D; MICRORNA 322; MICRORNA 34C; MICRORNA 376A; MICRORNA 450A 5P; MICRORNA 676; MICRORNA 99B; SIRTUIN 1; UNCLASSIFIED DRUG; UNINDEXED DRUG; MIRN204 MICRORNA, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE PROGRESSION; CELL MIGARTION; CELL PROLIFERATION; CELL PROLIFERATION ASSAY; CONTROLLED STUDY; CORNEA EPITHELIUM; CORNEA INJURY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; MOUSE; MTS ASSAY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; WOUND HEALING; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CORNEA; GENE EXPRESSION REGULATION; GENETICS; PHYSIOLOGY;

ANIMALS; CORNEA; FEMALE; GENE EXPRESSION REGULATION; MICE; MICE, INBRED C57BL; MICRORNAS; WOUND HEALING;

EID: 84939789495     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.15-16467     Document Type: Article

References (35)

1. Qazi Y, Wong G, Monson B, Stringham J, Ambati BK. Corneal transparency: genesis, maintenance and dysfunction. Brain Res Bull. 2010;81:198-210.
2. Lu L, Reinach PS, Kao WW. Corneal epithelial wound healing. Exp Biol Med (Maywood). 2001;226:653-664.
3. Schlotzer-Schrehardt U, Kruse FE. Identification and characterization of limbal stem cells. Exp Eye Res. 2005;81:247-264.
4. Carrington JC, Ambros V. Role of microRNAs in plant and animal development. Science. 2003;301:336-338.
5. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116:281-297.
6. Foshay KM, Gallicano GI. Small RNAs, big potential: the role of microRNAs in stem cell function. Curr Stem Cell Res Ther. 2007;2:264-271.
7. He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet. 2004;5:522-531.
8. Karali M, Peluso I, Gennarino VA, et al. miRNeye: a microRNA expression atlas of the mouse eye.BMC Genomics. 2010;11:715.
9. Funari VA, Winkler M, Brown J, Dimitrijevich SD, Ljubimov AV, Saghizadeh M. Differentially expressed wound healing-related microRNAs in the human diabetic cornea. PLoS One. 2013;8: e84425.
10. Robinson PM, Chuang TD, Sriram S, et al. MicroRNA signature in wound healing following excimer laser ablation: role of miR- 133b on TGFbeta1, CTGF, SMA, and COL1A1 expression levels in rabbit corneal fibroblasts. Invest Ophthalmol Vis Sci. 2013; 54:6944-6951.
11. Lin D, Halilovic A, Yue P, et al. Inhibition of miR-205 impairs the wound-healing process in human corneal epithelial cells by targeting KIR4.1 (KCNJ10). Invest Ophthalmol Vis Sci. 2013;54:6167-6178.
12. Wettenhall JM, Smyth GK. limmaGUI: a graphical user interface for linear modeling of microarray data. Bioinformatics. 2004;20:3705-3706.
13. Pan Z, Wang Z, Yang H, Zhang F, Reinach PS. TRPV1 activation is required for hypertonicity-stimulated inflammatory cytokine release in human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2011;52:485-493.
14. Tam WL, Weinberg RA. The epigenetics of epithelial-mesenchymal plasticity in cancer. Nat Med. 2013;19:1438-1449.
15. Li Y, Piatigorsky J. Targeted deletion of Dicer disrupts lens morphogenesis, corneal epithelium stratification, and whole eye development. Dev Dyn. 2009;238:2388-2400.
16. Peng H, Hamanaka RB, Katsnelson J, et al. MicroRNA-31 targets FIH-1 to positively regulate corneal epithelial glycogen metabolism. FASEB J. 2012;26:3140-3147.
17. Peng H, Kaplan N, Hamanaka RB, et al. microRNA-31/factorinhibiting hypoxia-inducible factor 1 nexus regulates keratinocyte differentiation. Proc Natl Acad Sci U S A. 2012;109: 14030-14034.
18. Yu J, Ryan DG, Getsios S, Oliveira-Fernandes M, Fatima A, Lavker RM. MicroRNA-184 antagonizes microRNA-205 to maintain SHIP2 levels in epithelia. Proc Natl Acad Sci U S A. 2008;105:19300-19305.
19. Geiss GK, Bumgarner RE, Birditt B, et al. Direct multiplexed measurement of gene expression with color-coded probe pairs. Nat Biotechnol. 2008;26:317-325.
20. Mestdagh P, Hartmann N, Baeriswyl L, et al. Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study. Nat Methods. 2014;11:809- 815.
21. Kulkarni MM. Digital multiplexed gene expression analysis using the NanoString nCounter system. Curr Protoc Mol Biol. 2011;Chapter 25:Unit25B.10.
22. Roderick C, Reinach PS, Wang L, Lu L. Modulation of rabbit corneal epithelial cell proliferation by growth factor-regulated K(+) channel activity. J Membr Biol. 2003;196:41-50.
23. Yang H, Sun X, Wang Z, et al. EGF stimulates growth by enhancing capacitative calcium entry in corneal epithelial cells. J Membr Biol. 2003;194:47-58.
24. Wang Z, Bildin VN, Yang H, Capo-Aponte JE, Yang Y, Reinach PS. Dependence of corneal epithelial cell proliferation on modulation of interactions between ERK1/2 and NKCC1. Cell Physiol Biochem. 2011;28:703-714.
25. Ryan DG, Oliveira-Fernandes M, Lavker RM. MicroRNAs of the mammalian eye display distinct and overlapping tissue specificity. Mol Vis. 2006;12:1175-1184.
26. Wang FE, Zhang C, Maminishkis A, et al. MicroRNA-204/211 alters epithelial physiology. FASEB J. 2010;24:1552-1571.
27. Conte I, Carrella S, Avellino R, et al. miR-204 is required for lens and retinal development via Meis2 targeting. Proc Natl Acad Sci U S A. 2010;107:15491-15496.
28. Aomatsu K, Arao T, Sugioka K, et al. TGF-beta induces sustained upregulation of SNAI1 and SNAI2 through Smad and non-Smad pathways in a human corneal epithelial cell line. Invest Ophthalmol Vis Sci. 2011;52:2437-2443.
29. Aomatsu K, Arao T, Abe K, et al. Slug is upregulated during wound healing and regulates cellular phenotypes in corneal epithelial cells. Invest Ophthalmol Vis Sci. 2012;53:751-756.
30. Wang Y, Li W, Zang X, et al. MicroRNA-204-5p regulates epithelial-to-mesenchymal transition during human posterior capsule opacification by targeting SMAD4. Invest Ophthalmol Vis Sci. 2013;54:323-332.
31. Qiu YH, Wei YP, Shen NJ, et al. miR-204 inhibits epithelial to mesenchymal transition by targeting slug in intrahepatic cholangiocarcinoma cells. Cell Physiol Biochem. 2013;32: 1331-1341.
32. Zhang L, Wang X, Chen P. MiR-204 down regulates SIRT1 and reverts SIRT1-induced epithelial-mesenchymal transition, anoikis resistance and invasion in gastric cancer cells. BMC Cancer. 2013;13:290.
33. Wang Y, Zhao X, Shi D, et al. Overexpression of SIRT1 promotes high glucose-attenuated corneal epithelial wound healing via p53 regulation of the IGFBP3/IGF-1R/AKT pathway. Invest Ophthalmol Vis Sci. 2013;54:3806-3814.
34. Lanford RE, Hildebrandt-Eriksen ES, Petri A, et al. Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science. 2010;327:198-201.
35. Janssen HL, Reesink HW, Lawitz EJ, et al. Treatment of HCV infection by targeting microRNA. New Engl J Med. 2013;368: 1685-1694.