Overexpression of SIRT1 promotes high glucose-attenuated corneal epithelial wound healing via p53 regulation of the IGFBP3/IGF-1R/AKT pathway.

Investigative ophthalmology & visual science

Volumn 54, Issue 5, 2013, Pages 3806-3814

  Wang, Y ^a   Zhao, Xiaowen ^a   Shi, Daling ^a   Chen, Peng ^a   Yu, Yang ^a   Yang, Lingling ^a   Xie, Lixin ^a  

^a not available ^*

Author keywords

[No Author keywords available]

Indexed keywords

BENZOTHIAZOLE DERIVATIVE; DRUG DERIVATIVE; GLUCOSE; IGFBP3 PROTEIN, HUMAN; PIFITHRIN; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN P53; SIRT1 PROTEIN, HUMAN; SIRTUIN 1; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C RECEPTOR; TOLUENE;

ANIMAL; ARTICLE; C57BL MOUSE; CELL CULTURE; CONFOCAL MICROSCOPY; CORNEA EPITHELIUM; CORNEAL WOUND HEALING; DIABETIC KERATOPATHY; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MALE; METABOLISM; MOUSE; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SIRT1; WESTERN BLOTTING; WOUND HEALING;

CORNEAL WOUND HEALING; DIABETIC KERATOPATHY; SIRT1;

ANIMALS; BENZOTHIAZOLES; BLOTTING, WESTERN; CELLS, CULTURED; DOWN-REGULATION; EPITHELIUM, CORNEAL; GENE EXPRESSION REGULATION; GLUCOSE; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; MALE; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, IGF TYPE 1; SIRTUIN 1; TOLUENE; TUMOR SUPPRESSOR PROTEIN P53; WOUND HEALING;

EID: 84881290825     PISSN: None     EISSN: 15525783     Source Type: None    
DOI: 10.1167/iovs.13-12091     Document Type: Article

References (0)