Asymptomatic children might transmit human parechovirus type 3 to neonates and young infants

Journal of Clinical Virology

Volumn 70, Issue , 2015, Pages 105-108

  Aizawa, Yuta ^a   Yamanaka, Takayuki ^b   Watanabe, Kanako ^c   Oishi, Tomohiro ^a   Saitoh, Akihiko ^a,d  

^a NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^b Niigata Kido Hospital   (Japan)

^c NIIGATA UNIVERSITY   (Japan)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Asymptomatic siblings; Epidemic; Feces; Human parechovirus type 3; Neonates; Transmission

Indexed keywords

ARTICLE; CEREBROSPINAL FLUID; CLINICAL ARTICLE; FECES ANALYSIS; HUMAN; HUMAN PARECHOVIRUS; HUMAN PARECHOVIRUS TYPE 3; HUMAN PARECHOVIRUS TYPE 3 INFECTION; INFANT; JAPAN; NEWBORN; NUCLEOTIDE SEQUENCE; PICORNAVIRUS INFECTION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; VIRUS TRANSMISSION; ASYMPTOMATIC INFECTION; CLASSIFICATION; CLINICAL TRIAL; CONTACT EXAMINATION; FAMILY; FECES; GENETICS; GENOTYPE; ISOLATION AND PURIFICATION; MULTICENTER STUDY; PARECHOVIRUS; PEDIGREE; PHYLOGENY; PICORNAVIRIDAE INFECTIONS; TRANSMISSION; VIROLOGY;

VIRUS RNA;

ASYMPTOMATIC INFECTIONS; CONTACT TRACING; FAMILY; FECES; GENOTYPE; HUMANS; INFANT; INFANT, NEWBORN; JAPAN; PARECHOVIRUS; PEDIGREE; PHYLOGENY; PICORNAVIRIDAE INFECTIONS; RNA, VIRAL;

EID: 84939643394     PISSN: 13866532     EISSN: 18735967     Source Type: Journal    
DOI: 10.1016/j.jcv.2015.07.300     Document Type: Article

References (24)

1. Vincent Racaniello R., et al. Picornaviridae: the viruses and their replication. Fields Virology 2013, Vol 1:610-664. Lippincott Williams and Wilkins, Philadelphia. 6th ed.
2. Esposito S., Rahamat-Langendoen J., Ascolese B., Senatore L., Castellazzi L., Niesters H.G. Pediatric parechovirus infections. J. Clin. Virol. 2014, 60:84-89.
3. Stanway G., Joki-Korpela P., Hyypia T. Human parechoviruses-biology and clinical significance. Rev. Med. Virol. 2000, 10:57-69.
4. Levorson R.E., Jantausch B.A., Wiedermann B.L., Spiegel H.M., Campos J.M. Human parechovirus-3 infection: emerging pathogen in neonatal sepsis. Pediatr. Infect. Dis. J. 2009, 28:545-547.
5. Boivin G., Abed Y., Boucher F.D. Human parechovirus 3 and neonatal infections. Emerg. Infect. Dis. 2005, 11:103-105.
6. Wolthers K.C., Benschop K.S., Schinkel J., Molenkamp R., Bergevoet R.M., Spijkerman I.J., et al. Human parechoviruses as an important viral cause of sepsislike illness and meningitis in young children. Clin. Infect. Dis. 2008, 47:358-363.
7. Shoji K., Komuro H., Miyata I., Miyairi I., Saitoh A. Dermatologic manifestations of human parechovirus type 3 infection in neonates and infants. Pediatr. Infect. Dis. J. 2013, 32:233-236.
8. Verboon-Maciolek M.A., Groenendaal F., Hahn C.D., Hellmann J., van Loon A.M., Boivin G., et al. Human parechovirus causes encephalitis with white matter injury in neonates. Ann. Neurol. 2008, 64:266-273.
9. Sedmak G., Nix W.A., Jentzen J., Haupt T.E., Davis J.P., Bhattacharyya S., et al. Infant deaths associated with human parechovirus infection in Wisconsin. Clin. Infect. Dis. 2010, 50:357-361.
10. Nix W.A., Maher K., Johansson E.S., Niklasson B., Lindberg A.M., Pallansch M.A., et al. Detection of all known parechoviruses by real-time PCR. J. Clin. Microbiol. 2008, 46:2519-2524.
11. Ito M., Yamashita T., Tsuzuki H., Takeda N., Sakae K. Isolation and identification of a novel human parechovirus. J. Gen. Virol. 2004, 85:391-398.
12. Harvala H., Robertson I., McWilliam Leitch E.C., Benschop K., Wolthers K.C., Templeton K., et al. Epidemiology and clinical associations of human parechovirus respiratory infections. J. Clin. Microbiol. 2008, 46:3446-3453.
13. Aizawa Y., Watanabe K., Oishi T., Hirano H., Hasegawa I., Saitoh A. Role of maternal antibodies in human parechovirus type 3 infection in young infants. Emerg. Infect. Dis. 2015, in press.
14. Calvert J., Chieochansin T., Benschop K.S., McWilliam Leitch E.C., Drexler J.F., Grywna K., et al. Recombination dynamics of human parechoviruses: investigation of type-specific differences in frequency and epidemiological correlates. J. Gen. Virol. 2010, 91:1229-1238.
15. Tamura K., Stecher G., Peterson D., Filipski A., Kumar S. MEGA6: molecular evolutionary genetics analysis version 6.0. Mol. Biol. Evol. 2013, 30:2725-2729.
16. Japanese Ministry of Health, Labour and Wealfare [homepage on the Internet]. Tokyo: Vital Statistics in 2013 [updated 2014 Sep 11; cited 2015 Feb 13].pdf. http://www.mhlw.go.jp/toukei/saikin/hw/jinkou/kakutei13/dl/08_h4.
17. Eis-Hubinger A.M., Eckerle I., Helmer A., Reber U., Dresbach T., Buderus S., et al. Two cases of sepsis-like illness in infants caused by human parechovirus traced back to elder siblings with mild gastroenteritis and respiratory symptoms. J. Clin. Microbiol. 2013, 51:715-718.
18. Mizuta K., Yamakawa T., Nagasawa H., Itagaki T., Katsushima F., Katsushima Y., et al. Epidemic myalgia associated with human parechovirus type 3 infection among adults occurs during an outbreak among children: findings from Yamagata, Japan, in 2011. J. Clin. Virol. 2013, 58:188-193.
19. Kolehmainen P., Oikarinen S., Koskiniemi M., Simell O., Ilonen J., Knip M., et al. Human parechoviruses are frequently detected in stool of healthy Finnish children. J. Clin. Virol. 2012, 54:156-161.
20. John Modlin F. Enteroviruses and Parechoviruses. Principles and Practice of Pediatric Infectious Diseases 2012, 1172-1180. Churchill Livingstone, New York. 4th ed. S.S. Long, L.K. Pickering, C.G. Prober (Eds.).
21. Chang L.Y., Tsao K.C., Hsia S.H., Shih S.R., Huang C.G., Chan W.K., et al. Transmission and clinical features of enterovirus 71 infections in household contacts in Taiwan. JAMA 2004, 291:222-227.
22. Matsuura K., Hasegawa S., Nakayama T., Morita O., Uetake H., Masaki A. Epidemiological studies on echovirus type 18 infection in Toyama prefecture. Microbiol. Immunol. 1983, 27:359-368.
23. Marques Mendanha de Oliveira D., Souza M., Souza Fiaccadori F., Cesar Pereira Santos H., das Dores de Paula Cardoso D. Monitoring of Calicivirus among day-care children: evidence of asymptomatic viral excretion and first report of GI. 7 Norovirus and GI. 3 Sapovirus in Brazil. J. Med. Virol. 2014, 86:1569-1575.
24. Yan L., Gao Y., Zhang Y., Tildesley M., Liu L., Zhang Y., et al. Epidemiological and virological characteristics of pandemic influenza A (H1N1) school outbreaks in China in 2009. PLoS One 2012, 7:e45898.