Pediatric parechovirus infections

Journal of Clinical Virology

Volumn 60, Issue 2, 2014, Pages 84-89

  Esposito, Susanna ^a   Rahamat Langendoen, Janette ^b   Ascolese, Beatrice ^a   Senatore, Laura ^a   Castellazzi, Luca ^a   Niesters, Hubert G M ^b  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Encephalitis; Human parechoviruses; Meningitis; Neonatal sepsis; Picornaviridae; Respiratory infection

Indexed keywords

ANTIVIRUS AGENT; GENOMIC RNA; GLUTAMIC ACID; GLYCINE; IMMUNOGLOBULIN; MONOCLONAL ANTIBODY; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; VIRUS PROTEIN;

AGE DISTRIBUTION; AMINO ACID SEQUENCE; ANTIVIRAL THERAPY; CARBOXY TERMINAL SEQUENCE; CENTRAL NERVOUS SYSTEM INFECTION; CHILDHOOD DISEASE; CLINICAL FEATURE; ENDOSOME; ERYTHEMA; EUROPE; FEVER; GASTROENTERITIS; HEMOPHAGOCYTIC SYNDROME; HUMAN; INFECTION RATE; JAPAN; LYMPHOCYTE COUNT; MENINGOENCEPHALITIS; MYALGIA; NASOPHARYNGEAL ASPIRATION; NONHUMAN; PARECHOVIRUS; PEDIATRIC PARECHOVIRUS INFECTION; PICORNAVIRUS INFECTION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY TRACT INFECTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SEROPREVALENCE; THROAT CULTURE; VIRUS CULTURE; VIRUS DIAGNOSIS; VIRUS ENCEPHALITIS; VIRUS PATHOGENESIS; ADOLESCENT; CHILD; CLASSIFICATION; GENETICS; GENOTYPE; INFANT; ISOLATION AND PURIFICATION; MOLECULAR DIAGNOSIS; NEWBORN; PICORNAVIRIDAE INFECTIONS; PRESCHOOL CHILD; RESPIRATORY TRACT INFECTIONS; SEPSIS; VIROLOGY;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; GASTROENTERITIS; GENOTYPE; HUMANS; INFANT; INFANT, NEWBORN; MENINGOENCEPHALITIS; MOLECULAR DIAGNOSTIC TECHNIQUES; PARECHOVIRUS; PICORNAVIRIDAE INFECTIONS; REAL-TIME POLYMERASE CHAIN REACTION; RESPIRATORY TRACT INFECTIONS; SEPSIS; VIRAL STRUCTURAL PROTEINS;

EID: 84900316036     PISSN: 13866532     EISSN: 18735967     Source Type: Journal    
DOI: 10.1016/j.jcv.2014.03.003     Document Type: Review

References (47)

1. Harvala H., Simmonds P. Human parechoviruses: biology, epidemiology and clinical significance. J Clin Virol 2009, 45:1-9.
2. Stanway G., Joki-Korpela P., Hyypiä T. Human parechoviruses - biology and clinical significance. Rev Med Virol 2000, 10:57-69.
3. Khetsuriani N., Lamonte A., Oberste M.S., Pallansch M. Neonatal enterovirus infections reported to the national enterovirus surveillance system in the United States, 1983-2003. Pediatr Infect Dis J 2006, 25:889-893.
4. Boivin G., Abed Y., Boucher F.D. Human parechovirus 3 and neonatal infections. Emerg Infect Dis 2005, 11:103-105.
5. Levorson R.E., Jantausch B.A. Human parechoviruses. Pediatr Infect Dis J 2009, 28:831-832.
6. van der Sanden S., de Bruin E., Vennema H., Swanink C., Koopmans M., van der Avoort H. Prevalence of human parechovirus in the Netherlands in 2000 to 2007. J Clin Microbiol 2008, 46:2489-2884.
7. Harvala H., Robertson I., Chieochansin T., McWilliam Leitch E.C., Templeton K., Simmonds P. Specific association of human parechovirus type 3 with sepsis and fever in young infants, as identified by direct typing of cerebrospinal fluid samples. J Infect Dis 2009, 199:1753-1760.
8. Mizuta K., Kuroda M., Kurimura M., Yahata Y., Sekizuka T., Aoki Y., et al. Epidemic myalgia in adults associated with human parechovirus type 3 infection, Yamagata, Japan, 2008. Emerg Infect Dis 2012, 18:1787-1793.
9. Harvala H., McLeish N., Kondracka J., McIntyre C.L., McWilliam Leitch E.C., Templeton K., et al. Comparison of human parechovirus and enterovirus detection frequencies in cerebrospinal fluid samples collected over a 5-year period in Edinburgh: HPeV type 3 identified as the most common picornavirus type. J Med Virol 2011, 83:889-896.
10. Harvala H., Wolthers K.C., Simmonds P. Parechoviruses in children: understanding a new infection. Curr Opin Infect Dis 2010, 23:224-230.
11. Chieochansin T., Vichiwattana P., Korkong S., Theamboonlers A., Poovorawan Y. Molecular epidemiology, genome characterization, and recombination event of human parechovirus. Virology 2011, 421:159-166.
12. Schuffenecker I., Javouhey E., Gillet Y., Kugener B., Billaud G., Floret D., et al. Human parechovirus infections, Lyon, France, 2008-10: evidence for severe cases. J Clin Virol 2012, 54:337-341.
13. Piralla A., Furione M., Rovida F., Marchi A., Stronati M., Gerna G., et al. Human parechovirus infections in patients admitted to hospital in Northern Italy, 2008-2010. J Med Virol 2012, 84:686-690.
14. Walters B., Peñaranda S., Nix W.A., Oberste M.S., Todd K.M., Katz B.Z., et al. Detection of human parechovirus(HPeV)-3 in spinal fluid specimens from pediatric patients in the Chicago area. J Clin Virol 2011, 52:187-191.
15. Selvarangan R., Nzabi M., Selvaraju S.B., Ketter P., Carpenter C., Harrison C.J. Human parechovirus 3 causing sepsis-like illness in children from midwestern United States. Pediatr Infect Dis J 2011, 30:238-242.
16. Kolehmainen P., Oikarinen S., Koskiniemi M., Simell O., Ilonen J., Knip M., et al. Human parechoviruses are frequently detected in stool of healthy Finnish children. J Clin Virol 2012, 54:156-161.
17. Felsenstein S., Yang S., Eubanks N., Sobrera E., Grimm J.P., Aldrovandi G. Human parechovirus central nervous system infections in Southern California children. Pediatr Infect Dis J 2013, [Epub October 7].
18. Westerhuis B.M., Koen G., Wildenbeest J.G., Pajkrt D., de Jong M.D., Benschop K.S., et al. Specific cell tropism and neutralization of human parechovirus types 1 and 3: implications for pathogenesis and therapy development. J Gen Virol 2012, 93(Pt 11):2363-2370.
19. Triantafilou K., Vakakis E., Orthopoulos G., Ahmed M.A., Schumann C., Lepper P.M., et al. TLR8 and TLR7 are involved in the host's immune response to human parechovirus 1. Eur J Immunol 2005, 35:2416-2423.
20. Sainato R., Flanagan R., Mahlen S., Fairchok M., Braun L. Severe human parechovirus sepsis beyond the neonatal period. J Clin Virol 2011, 51:73-74.
21. Verboon-Maciolek M.A., Krediet T.G., Gerards L.J., de Vries L.S., Groenendaal F., van Loon A.M. Severe neonatal parechovirus infection and similarity with enterovirus infection. Pediatr Infect Dis J 2008, 27:241-245.
22. Sharp J., Harrison C.J., Puckett K., Selvaraju S.B., Penaranda S., Nix W.A., et al. Characteristics of young infants in whom human parechovirus, enterovirus or neither were detected in cerebrospinal fluid during sepsis evaluations. Pediatr Infect Dis J 2013, 32:213-216.
23. Volpe J.J. Neonatal encephalitis and white matter injury: more than just inflammation. Ann Neurol 2008, 64:232-236.
24. Verboon-Maciolek M.A., Groenendaal F., Hahn C.D., Hellmann J., van Loon A.M., Boivin G., et al. Human parechovirus causes encephalitis with white matter injury in neonates. Ann Neurol 2008, 64:266-273.
25. Renna S., Bergamino L., Pirlo D., Rossi A., Furione M., Piralla A., et al. A case of neonatal human parechovirus encephalitis with a favourable outcome. Brain Dev 2013, [Epub January 21].
26. Jääskeläinen A.J., Kolehmainen P., Kallio-Kokko H., Nieminen T., Koskiniemi M., Tauriainen S., et al. First two cases of neonatal human parechovirus 4 infection with manifestation of suspected sepsis, Finland. J Clin Virol 2013, 58:328-330.
27. Pajkrt D., Benschop K.S., Westerhuis B., Molenkamp R., Spanjerberg L., Wolthers K.C. Clinical characteristics of human parechoviruses 4-6 infections in young children. Pediatr Infect Dis J 2009, 28:1008-1010.
28. Benschop K.S., Schinkel J., Minnaar R.P., Pajkrt D., Spanjerberg L., Kraakman H.C., et al. Human parechovirus infections in Dutch children and the association between serotype and disease severity. Clin Infect Dis 2006, 42:204-210.
29. Tauriainen S., Oikarinen S., Taimen K., Laranne J., Sipilä M., Lönnrot M., et al. Temporal relationship between human parechovirus 1 infection and otitis media in young children. J Infect Dis 2008, 198:5-40.
30. Harvala H., Robertson I., McWilliam Leitch E.C., Benschop K., Wolthers K.C., Templeton K., et al. Epidemiology and clinical associations of human parechovirus respiratory infections. J Clin Microbiol 2008, 46:3446-3453.
31. Shoji K., Komuro H., Miyata I., Miyairi I., Saitoh A. Dermatologic manifestations of human parechovirus type 3 infection in neonates and infants. Pediatr Infect Dis J 2013, 32:233-236.
32. Shoji K., Komuro H., Kobayashi Y., Shike T., Funaki T., Katsuta T., et al. An infant with human parechovirus type 3 infection with a distinctive rash on the extremities. Pediatr Dermatol 2012, [Epub September 3].
33. Aviner S., Sofer D., Shulman L.M., Bibi H., Weitzman S. Hemophagocytic lymphohistiocytosis associated with Parechovirus 3 infection. J Pediatr Hematol Oncol 2013, [Epub September 25].
34. Yuzurihara S.S., Ao K., Hara T., Tanaka F., Mori M., Kikuchi N., et al. Human parechovirus-3 infection in nine neonates and infants presenting symptoms of hemophagocytic lymphohistiocytosis. J Infect Chemother 2013, 19:144-148.
35. Wildenbeest J.G., Wolthers K.C., Straver B., Pajkrt D. Successful IVIG treatment of human parechovirus-associated dilated cardiomyopathy in an infant. Pediatrics 2013, 132:e243-e247.
36. Levorson R.E., Jantausch B.A., Wiedermann B.L., Spiegel H.M., Campos J.M. Human parechovirus-3 infection: emerging pathogen in neonatal sepsis. Pediatr Infect Dis J 2009, 28:545-547.
37. Watanabe K., Oie M., Higuchi M., Nishikawa M., Fujii M. Isolation and characterization of a novel human parechovirus from clinical samples. Emerg Infect Dis 2007, 13:889-895.
38. Kolehmainen P., Koskiniemi M., Oikarinen S., Veijola R., Simell O., Ilonen J., et al. Human parechovirus and the risk of type 1 diabetes. J Med Virol 2013, 85:1619-1623.
39. Tauriainen S., Martiskainen M., Oikarinen S., Lönnrot M., Viskari H., Ilonen J., et al. Human parechovirus 1 infections in young children-no association with type 1 diabetes. J Med Virol 2007, 79:457-462.
40. Wildenbeest J.G., Harvala H., Pajkrt D., Wolthers K.C. The need for treatment against human parechoviruses: how, why and when. Expert Rev Anti Infect Ther 2010, 8:1417-1429.
41. Nix W.A., Maher K., Johansson E.S., Niklasson B., Lindberg A.M., Pallansch M.A., et al. Detection of all known parechoviruses by real-time PCR. J Clin Microbiol 2008, 46:2519-2524.
42. Wolthers K.C., Benschop K.S., Schinkel J., Molenkamp R., Bergevoet R.M., Spijkerman I.J., et al. Human parechoviruses as an important viral cause of sepsislike illness and meningitis in young children. Clin Infect Dis 2008, 47:358-363.
43. de Crom S.C., Obihara C.C., de Moor R.A., Veldkamp E.J., van Furth A.M., Rossen J.W. Prospective comparison of the detection rates of human enterovirus and parechovirus RT-qPCR and viral culture in different pediatric specimens. J Clin Virol 2013, 58:449-454.
44. De Palma A.M., Pürstinger G., Wimmer E., Patick A.K., Andries K., Rombaut B., et al. Potential use of antiviral agents in polio eradication. Emerg Infect Dis 2008, 14:545-551.
45. Li C., Wang H., Shih S.R., Chen T.C., Li M.L. The efficacy of viral capsid inhibitors in human enterovirus infection and associated diseases. Curr Med Chem 2007, 14:847-856.
46. Friesen R.H., Koudstaal W., Koldijk M.H., Weverling G.J., Brakenhoff J.P., Lenting P.J., et al. New class of monoclonal antibodies against severe influenza: prophylactic and therapeutic efficacy in ferrets. PLoS ONE 2010, 5:e9106.
47. Joki-Korpela P., Roivainen M., Lankinen H., Pöyry T., Hyypiä T. Antigenic properties of human parechovirus 1. J Gen Virol 2000, 81:1709-1718.