Antioxidant Activity and Induction of mRNA Expressions of Antioxidant Enzymes in HEK-293 Cells of Moringa oleifera Leaf Extract

Planta Medica

Volumn 81, Issue 12-13, 2015, Pages 1084-1089

  Vongsak, Boonyadist ^a   Mangmool, Supachoke ^a   Gritsanapan, Wandee ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

Author keywords

antioxidant enzymes; isoquercetin; kidney cell; Moringa oleifera; Moringaceae; reactive oxygen species

Indexed keywords

ASTRAGALIN; CHLOROGENIC ACID; CRYPTO CHLOROGENIC ACID; HEME OXYGENASE 1; HYDROGEN PEROXIDE; ISOQUERCETIN; MESSENGER RNA; MORINGA OLEIFERA EXTRACT; QUERCETIN DERIVATIVE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TROLOX C; UNCLASSIFIED DRUG; ANTIOXIDANT; CATALASE; FLAVONOID; KAEMPFEROL DERIVATIVE; PHENOL DERIVATIVE; PLANT EXTRACT;

ABTS RADICAL SCAVENGING ASSAY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DPPH RADICAL SCAVENGING ASSAY; DRY POWDER; DRY WEIGHT; EMBRYO; GENE EXPRESSION; GENE INDUCTION; HEK293 CELL LINE; HUMAN; HUMAN CELL; IC50; MORINGA OLEIFERA; MRNA EXPRESSION ASSAY; MTT ASSAY; PLANT LEAF; THAILAND; CHEMISTRY; DRUG EFFECTS; GENETICS; METABOLISM; OXIDATION REDUCTION REACTION;

MORINGA OLEIFERA; MORINGACEAE;

ANTIOXIDANTS; CATALASE; CHLOROGENIC ACID; FLAVONOIDS; HEK293 CELLS; HEME OXYGENASE-1; HUMANS; HYDROGEN PEROXIDE; KAEMPFEROLS; MORINGA OLEIFERA; OXIDATION-REDUCTION; PHENOLS; PLANT EXTRACTS; PLANT LEAVES; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SUPEROXIDE DISMUTASE;

EID: 84939616670     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0035-1546168     Document Type: Article

References (25)

1. Turvey S. E., Broide D. H. Innate immunity. J Allergy Clin Immunol: 2010; 125 02 S24 S32
2. Jantan I., Bukhari S. NA, Lajis N. H., Abas F., Wai L. K., Jasamai M. Effects of diarylpentanoid analogues of curcumin on chemiluminescence and chemotactic activities of phagocytes. J Pharm Pharmacol: 2012; 64 404 412
3. Atmani D., Chaher N., Berboucha M., Ayouni K., Lounis H., Boudaoud H., Debbache N., Atmani D. Antioxidant capacity and phenol content of selected Algerian medicinal plants. Food Chem: 2009; 112 303 309
4. Sunil C., Ignacimuthu S. In vitro and in vivo antioxidant activity of Symplocos cochinchinensis S. Moore leaves containing phenolic compounds. Food Chem Toxicol: 2011; 49 1604 1609
5. Pandanaboina S. C., Kondeti S. R., Rajbanshi S. L., Kunala P. N., Pandanaboina S., Pandanaboina M. M., Wudayagiri R. Alterations in antioxidant enzyme activities and oxidative damage in alcoholic rat tissues: Protective role of Thespesia populnea. Food Chem: 2012; 132 150 159
6. 2-induced PC12 cell death via Nrf2/ARE activation. Bioorg Med Chem: 2010; 18 3133 3139
7. Hu W., Yu L., Wang M. H. Antioxidant and antiproliferative properties of water extract from Mahonia bealei (Fort.) Carr. leaves. Food Chem Toxicol: 2011; 49 799 806
8. Anwar F., Latif S., Ashraf M., Gilani A. H. Moringa oleifera: a food plant with multiple medicinal uses. Phytother Res: 2007; 21 17 25
9. Pandey A., Pradheep K., Gupta R., Nayar E. R., Bhandari D. C. 'Drumstick tree' (Moringa oleifera Lam.): a multipurpose potential species in India. Genet Resour Crop Evol: 2010; 58 453 460
10. Sahakitpichan P., Mahidol C., Disadee W., Ruchirawat S., Kanchanapoom T. Unusual glycosides of pyrrole alkaloid and 4′-hydroxyphenylethanamide from leaves of Moringa oleifera. Phytochemistry: 2011; 72 791 795
11. Chumark P., Khunawat P., Sanvarinda Y., Phornchirasilp S., Morales N. P., Phivthong-Ngam L., Ratanachamnong P., Srisawat S., Pongrapeeporn K. S. The in vitro and ex vivo antioxidant properties, hypolipidaemic and antiatherosclerotic activities of water extract of Moringa oleifera Lam. leaves. J Ethnopharmacol: 2008; 116 439 446
12. Verma A. R., Vijayakumar M., Rao C. V., Mathela C. S. In vitro and in vivo antioxidant properties and DNA damage protective activity of green fruit of Ficus glomerata. Food Chem Toxicol: 2010; 48 704 709
13. Iqbal S., Bhanger M. I. Effect of season and production location on antioxidant activity of Moringa oleifera leaves grown in Pakistan. J Food Compost Anal: 2006; 19 544 551
14. Vongsak B., Sithisarn P., Gritsanapan W. HPLC quantitative analysis of three major antioxidant components of Moringa oleifera leaf extracts. Planta Med: 2012; 78 1252
15. Fernandez J., Reyes R., Ponce H., Oropeza M., Vancalsteren M. R., Jankowski C., Campos M. G. Isoquercitrin from Argemone platyceras inhibits carbachol and leukotriene D4-induced contraction in guinea-pig airways. Eur J Pharmacol: 2005; 522 108 115
16. Ouédraogo M., Lamien-Sanou A., Ramdé N., Ouédraogo A. S., Ouédraogo M., Zongo S. P., Goumbri O., Duez P., Guissou P. I. Protective effect of Moringa oleifera leaves against gentamicin-induced nephrotoxicity in rabbits. Exp Pathol: 2013; 65 335 339
17. Yeh C. T., Ching L. C., Yen G. C. Inducing gene expression of cardiac antioxidant enzymes by dietary phenolic acids in rats. J Nutr Biochem: 2009; 20 163 771
18. Vongsak B., Sithisarn P., Gritsanapan W. Bioactive contents and free radical scavenging activity of Moringa oleifera leaf extract under different storage conditions. Ind Crops Prod: 2013; 49 419 421
19. Faithong N., Benjakul S., Phatcharat S., Binsan W. Chemical composition and antioxidative activity of Thai traditional fermented shrimp and krill products. Food Chem: 2010; 119 133 140
20. Ferreira I. CFR, Baptista P., Vilas-Boas M., Barros L. Free-radical scavenging capacity and reducing power of wild edible mushrooms from northeast Portugal: Individual cap and stipe activity. Food Chem: 2007; 100 1511 1516
21. Kosem N., Han Y. H., Moongkarndi P. Antioxidant and cytoprotective activities of methanolic extract from Garcinia mangostana hulls. Sci Asia: 2007; 33 283 292
22. Hansen P. B., Poulsen C. B., Walter S., Marcussen N., Cribbs L. L., Skott O., Jensen B. L. Functional importance of L- and P/Q-type voltage-gated calcium channels in human renal vasculature. Hypertension: 2011; 58 464 470
23. Ferret P. J., Soum E., Negre O., Fradelizi D. Auto-protective redox buffering systems in stimulated macrophages. BMC Immunol: 2002; 3 3
24. Schmidt A. J., Hemmeter U. M., Krieg J. C., Vedder H., Heiser P. Impact of haloperidol and quetiapine on the expression of genes encoding antioxidant enzymes in human neuroblastoma SH-SY5Y cells. J Psychiatr Res: 2009; 43 818 823
25. Yoshiki N., Kubota T., Aso T. Identification of heme oxygenase in human endometrium. J Clin Endocrinol Metab: 2001; 86 5033 5038