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Volumn 34, Issue 33, 2015, Pages 4379-4390

FOXC2 promotes colorectal cancer metastasis by directly targeting MET

Author keywords

[No Author keywords available]

Indexed keywords

CATENIN; NERVE CELL ADHESION MOLECULE; PROTEIN P120; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; TRANSCRIPTION FACTOR FOXC2; UVOMORULIN; VIMENTIN; FORKHEAD TRANSCRIPTION FACTOR;

EID: 84939568163     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2014.368     Document Type: Article
Times cited : (70)

References (43)
  • 2
    • 84877275135 scopus 로고    scopus 로고
    • Regorafenib for metastatic colorectal cancer-authors' reply
    • Van Cutsem E, Grothey A. Regorafenib for metastatic colorectal cancer-authors' reply. Lancet 2013; 381: 1538-1539.
    • (2013) Lancet , vol.381 , pp. 1538-1539
    • Van Cutsem, E.1    Grothey, A.2
  • 3
    • 34249881055 scopus 로고    scopus 로고
    • Tumour markers in colorectal cancer: European Group on Tumour Markers (EGTM) guidelines for clinical use
    • Duffy MJ, van Dalen A, Haglund C, Hansson L, Holinski-Feder E, Klapdor R et al. Tumour markers in colorectal cancer: European Group on Tumour Markers (EGTM) guidelines for clinical use. Eur J Cancer 2007; 43: 1348-1360.
    • (2007) Eur J Cancer , vol.43 , pp. 1348-1360
    • Duffy, M.J.1    Van Dalen, A.2    Haglund, C.3    Hansson, L.4    Holinski-Feder, E.5    Klapdor, R.6
  • 4
    • 72449176846 scopus 로고    scopus 로고
    • Molecular origins of cancer: Molecular basis of colorectal cancer
    • Markowitz SD, Bertagnolli MM. Molecular origins of cancer: molecular basis of colorectal cancer. New Engl J Med 2009; 361: 2449-2460.
    • (2009) New Engl J Med , vol.361 , pp. 2449-2460
    • Markowitz, S.D.1    Bertagnolli, M.M.2
  • 5
    • 53049104725 scopus 로고    scopus 로고
    • The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression
    • Hayashi H, Sano H, Seo S, Kume T. The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression. J Biol Chem 2008; 283: 23791-23800.
    • (2008) J Biol Chem , vol.283 , pp. 23791-23800
    • Hayashi, H.1    Sano, H.2    Seo, S.3    Kume, T.4
  • 6
    • 84855606292 scopus 로고    scopus 로고
    • The role of FoxC2 transcription factor in tumor angiogenesis
    • Kume T. The role of FoxC2 transcription factor in tumor angiogenesis. J Oncol 2012; 2012: 204593.
    • (2012) J Oncol , vol.2012 , pp. 204593
    • Kume, T.1
  • 8
    • 34547141894 scopus 로고    scopus 로고
    • Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers
    • Mani SA, Yang J, Brooks M, Schwaninger G, Zhou A, Miura N et al. Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers. Proc Natl Acad Sci USA 2007; 104: 10069-10074.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 10069-10074
    • Mani, S.A.1    Yang, J.2    Brooks, M.3    Schwaninger, G.4    Zhou, A.5    Miura, N.6
  • 9
    • 84875473628 scopus 로고    scopus 로고
    • FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer
    • Hollier BG, Tinnirello AA, Werden SJ, Evans KW, Taube JH, Sarkar TR et al. FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer. Cancer Res 2013; 73: 1981-1992.
    • (2013) Cancer Res , vol.73 , pp. 1981-1992
    • Hollier, B.G.1    Tinnirello, A.A.2    Werden, S.J.3    Evans, K.W.4    Taube, J.H.5    Sarkar, T.R.6
  • 10
    • 79951551966 scopus 로고    scopus 로고
    • FOXC2 is a novel prognostic factor in human esophageal squamous cell carcinoma
    • Nishida N, Mimori K, Yokobori T, Sudo T, Tanaka F, Shibata K et al. FOXC2 is a novel prognostic factor in human esophageal squamous cell carcinoma. Ann Surg Oncol 2011; 18: 535-542.
    • (2011) Ann Surg Oncol , vol.18 , pp. 535-542
    • Nishida, N.1    Mimori, K.2    Yokobori, T.3    Sudo, T.4    Tanaka, F.5    Shibata, K.6
  • 11
    • 84877899742 scopus 로고    scopus 로고
    • The clinical significance of mesenchyme forkhead 1 (FoxC2) in gastric carcinoma
    • Zhu JL, Song YX, Wang ZN, Gao P, Wang MX, Dong YL et al. The clinical significance of mesenchyme forkhead 1 (FoxC2) in gastric carcinoma. Histopathology 2013; 62: 1038-1048.
    • (2013) Histopathology , vol.62 , pp. 1038-1048
    • Zhu, J.L.1    Song, Y.X.2    Wang, Z.N.3    Gao, P.4    Wang, M.X.5    Dong, Y.L.6
  • 12
    • 84861617311 scopus 로고    scopus 로고
    • Prognostic role of Twist, Slug, and Foxc2 expression in stage i non-small-cell lung cancer after curative resection
    • Jiang W, Pang XG, Wang Q, Shen YX, Chen XK, Xi JJ. Prognostic role of Twist, Slug, and Foxc2 expression in stage I non-small-cell lung cancer after curative resection. Clin Lung Cancer 2012; 13: 280-287.
    • (2012) Clin Lung Cancer , vol.13 , pp. 280-287
    • Jiang, W.1    Pang, X.G.2    Wang, Q.3    Shen, Y.X.4    Chen, X.K.5    Xi, J.J.6
  • 13
    • 84873056468 scopus 로고    scopus 로고
    • MIR-520h-mediated FOXC2 regulation is critical for inhibition of lung cancer progression by resveratrol
    • Yu YH, Chen HA, Chen PS, Cheng YJ, Hsu WH, Chang YW et al. MiR-520h-mediated FOXC2 regulation is critical for inhibition of lung cancer progression by resveratrol. Oncogene 2013; 32: 431-443.
    • (2013) Oncogene , vol.32 , pp. 431-443
    • Yu, Y.H.1    Chen, H.A.2    Chen, P.S.3    Cheng, Y.J.4    Hsu, W.H.5    Chang, Y.W.6
  • 14
    • 77952919218 scopus 로고    scopus 로고
    • P120-catenin is transcriptionally downregulated by FOXC2 in non-small cell lung cancer cells
    • Mortazavi F, An J, Dubinett S, Rettig M. p120-catenin is transcriptionally downregulated by FOXC2 in non-small cell lung cancer cells. Mol Cancer Res 2010; 8: 762-774.
    • (2010) Mol Cancer Res , vol.8 , pp. 762-774
    • Mortazavi, F.1    An, J.2    Dubinett, S.3    Rettig, M.4
  • 15
    • 63049090100 scopus 로고    scopus 로고
    • Metastasis: From dissemination to organ-specific colonization
    • Nguyen DX, Bos PD, Massague J. Metastasis: from dissemination to organ-specific colonization. Nat Rev Cancer 2009; 9: 274-284.
    • (2009) Nat Rev Cancer , vol.9 , pp. 274-284
    • Nguyen, D.X.1    Bos, P.D.2    Massague, J.3
  • 16
    • 80054686286 scopus 로고    scopus 로고
    • Tumor metastasis: Molecular insights and evolving paradigms
    • Valastyan S, Weinberg RA. Tumor metastasis: molecular insights and evolving paradigms. Cell 2011; 147: 275-292.
    • (2011) Cell , vol.147 , pp. 275-292
    • Valastyan, S.1    Weinberg, R.A.2
  • 17
    • 48249143579 scopus 로고    scopus 로고
    • FOXC2 controls Ang-2 expression and modulates angiogenesis, vascular patterning, remodeling, and functions in adipose tissue
    • Xue Y, Cao R, Nilsson D, Chen S, Westergren R, Hedlund EM et al. FOXC2 controls Ang-2 expression and modulates angiogenesis, vascular patterning, remodeling, and functions in adipose tissue. Proc Natl Acad Sci USA 2008; 105: 10167-10172.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 10167-10172
    • Xue, Y.1    Cao, R.2    Nilsson, D.3    Chen, S.4    Westergren, R.5    Hedlund, E.M.6
  • 18
    • 0028946604 scopus 로고
    • Overexpression and amplification of the met/HGF receptor gene during the progression of colorectal cancer
    • Di Renzo MF, Olivero M, Giacomini A, Porte H, Chastre E, Mirossay L et al. Overexpression and amplification of the met/HGF receptor gene during the progression of colorectal cancer. Clin Cancer Res 1995; 1: 147-154.
    • (1995) Clin Cancer Res , vol.1 , pp. 147-154
    • Di Renzo, M.F.1    Olivero, M.2    Giacomini, A.3    Porte, H.4    Chastre, E.5    Mirossay, L.6
  • 20
    • 33847390775 scopus 로고    scopus 로고
    • C-Met and hepatocyte growth factor: Potential as novel targets in cancer therapy
    • Sattler M, Salgia R. c-Met and hepatocyte growth factor: potential as novel targets in cancer therapy. Curr Oncol Rep 2007; 9: 102-108.
    • (2007) Curr Oncol Rep , vol.9 , pp. 102-108
    • Sattler, M.1    Salgia, R.2
  • 21
    • 33749367676 scopus 로고    scopus 로고
    • The Met pathway: Master switch and drug target in cancer progression
    • Mazzone M, Comoglio PM. The Met pathway: master switch and drug target in cancer progression. FASEB J 2006; 20: 1611-1621.
    • (2006) FASEB J , vol.20 , pp. 1611-1621
    • Mazzone, M.1    Comoglio, P.M.2
  • 22
  • 24
    • 0036221263 scopus 로고    scopus 로고
    • Dysregulation of Met receptor tyrosine kinase activity in invasive tumors
    • Danilkovitch-Miagkova A, Zbar B. Dysregulation of Met receptor tyrosine kinase activity in invasive tumors. J Clin Invest 2002; 109: 863-867.
    • (2002) J Clin Invest , vol.109 , pp. 863-867
    • Danilkovitch-Miagkova, A.1    Zbar, B.2
  • 25
    • 75149131636 scopus 로고    scopus 로고
    • MET Is highly expressed in advanced stages of colorectal cancer and indicates worse prognosis and mortality
    • De Oliveira AT, Matos D, Logullo AF, DA Silva SR, Neto RA, Filho AL et al. MET Is highly expressed in advanced stages of colorectal cancer and indicates worse prognosis and mortality. Anticancer Res 2009; 29: 4807-4811.
    • (2009) Anticancer Res , vol.29 , pp. 4807-4811
    • De Oliveira, A.T.1    Matos, D.2    Logullo, A.F.3    Silva, S.R.D.A.4    Neto, R.A.5    Filho, A.L.6
  • 26
    • 0037386758 scopus 로고    scopus 로고
    • C-MET expression level in primary colon cancer: A predictor of tumor invasion and lymph node metastases
    • Takeuchi H, Bilchik A, Saha S, Turner R, Wiese D, Tanaka M et al. c-MET expression level in primary colon cancer: a predictor of tumor invasion and lymph node metastases. Clin Cancer Res 2003; 9: 1480-1488.
    • (2003) Clin Cancer Res , vol.9 , pp. 1480-1488
    • Takeuchi, H.1    Bilchik, A.2    Saha, S.3    Turner, R.4    Wiese, D.5    Tanaka, M.6
  • 27
    • 33847326735 scopus 로고    scopus 로고
    • Molecular co-expression of the c-Met oncogene and hepatocyte growth factor in primary colon cancer predicts tumor stage and clinical outcome
    • Kammula US, Kuntz EJ, Francone TD, Zeng Z, Shia J, Landmann RG et al. Molecular co-expression of the c-Met oncogene and hepatocyte growth factor in primary colon cancer predicts tumor stage and clinical outcome. Cancer Lett 2007; 248: 219-228.
    • (2007) Cancer Lett , vol.248 , pp. 219-228
    • Kammula, U.S.1    Kuntz, E.J.2    Francone, T.D.3    Zeng, Z.4    Shia, J.5    Landmann, R.G.6
  • 28
    • 0026595807 scopus 로고
    • Overexpression of c-met proto-oncogene but not epidermal growth factor receptor or c-ERBB-2 in primary human colorectal carcinomas
    • Liu C, Park M, Tsao MS. Overexpression of c-met proto-oncogene but not epidermal growth factor receptor or c-erbB-2 in primary human colorectal carcinomas. Oncogene 1992; 7: 181-185.
    • (1992) Oncogene , vol.7 , pp. 181-185
    • Liu, C.1    Park, M.2    Tsao, M.S.3
  • 29
    • 43949111293 scopus 로고    scopus 로고
    • C-Met gene amplification is associated with advanced stage colorectal cancer and liver metastases
    • Zeng ZS, Weiser MR, Kuntz E, Chen CT, Khan SA, Forslund A et al. c-Met gene amplification is associated with advanced stage colorectal cancer and liver metastases. Cancer Lett 2008; 265: 258-269.
    • (2008) Cancer Lett , vol.265 , pp. 258-269
    • Zeng, Z.S.1    Weiser, M.R.2    Kuntz, E.3    Chen, C.T.4    Khan, S.A.5    Forslund, A.6
  • 31
    • 0037105707 scopus 로고    scopus 로고
    • Wnt signaling regulates expression of the receptor tyrosine kinase met in colorectal cancer
    • Boon EM, van der Neut R, van de Wetering M, Clevers H, Pals ST. Wnt signaling regulates expression of the receptor tyrosine kinase met in colorectal cancer. Cancer Res 2002; 62: 5126-5128.
    • (2002) Cancer Res , vol.62 , pp. 5126-5128
    • Boon, E.M.1    Van Der Neut, R.2    Van De Wetering, M.3    Clevers, H.4    Pals, S.T.5
  • 32
    • 33847014441 scopus 로고    scopus 로고
    • A positive feedback loop between hepatocyte growth factor receptor and betacatenin sustains colorectal cancer cell invasive growth
    • Rasola A, Fassetta M, De Bacco F, D'Alessandro L, Gramaglia D, Di Renzo MF et al. A positive feedback loop between hepatocyte growth factor receptor and betacatenin sustains colorectal cancer cell invasive growth. Oncogene 2007; 26: 1078-1087.
    • (2007) Oncogene , vol.26 , pp. 1078-1087
    • Rasola, A.1    Fassetta, M.2    De Bacco, F.3    D'Alessandro, L.4    Gramaglia, D.5    Di Renzo, M.F.6
  • 33
    • 34547141354 scopus 로고    scopus 로고
    • Clinical Schlag PM. Biological, and molecular aspects of metastasis in colorectal cancer
    • Stein U, Clinical Schlag PM. biological, and molecular aspects of metastasis in colorectal cancer. Recent Results Cancer Res 2007; 176: 61-80.
    • (2007) Recent Results Cancer Res , vol.176 , pp. 61-80
    • Stein, U.1
  • 34
    • 58149352266 scopus 로고    scopus 로고
    • MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis
    • Stein U, Walther W, Arlt F, Schwabe H, Smith J, Fichtner I et al. MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis. Nat Med 2009; 15: 59-67.
    • (2009) Nat Med , vol.15 , pp. 59-67
    • Stein, U.1    Walther, W.2    Arlt, F.3    Schwabe, H.4    Smith, J.5    Fichtner, I.6
  • 35
    • 0032541006 scopus 로고    scopus 로고
    • The human hepatocyte growth factor receptor gene: Complete structural organization and promoter characterization
    • Liu Y. The human hepatocyte growth factor receptor gene: complete structural organization and promoter characterization. Gene 1998; 215: 159-169.
    • (1998) Gene , vol.215 , pp. 159-169
    • Liu, Y.1
  • 36
    • 6944238395 scopus 로고    scopus 로고
    • Sp1 regulates expression of MET, and ribozyme-induced down-regulation of MET in fibrosarcoma-derived human cells reduces or eliminates their tumorigenicity
    • Liang H, O'Reilly S, Liu Y, Abounader R, Laterra J, Maher VM et al. Sp1 regulates expression of MET, and ribozyme-induced down-regulation of MET in fibrosarcoma-derived human cells reduces or eliminates their tumorigenicity. Int J Oncol 2004; 24: 1057-1067.
    • (2004) Int J Oncol , vol.24 , pp. 1057-1067
    • Liang, H.1    O'Reilly, S.2    Liu, Y.3    Abounader, R.4    Laterra, J.5    Maher, V.M.6
  • 38
    • 84879472789 scopus 로고    scopus 로고
    • High Expression of FLOT1 is associated with progression and poor prognosis in hepatocellular carcinoma
    • Zhang SH, Wang CJ, Shi L, Li XH, Zhou J, Song LB et al. High Expression of FLOT1 is associated with progression and poor prognosis in hepatocellular carcinoma. PLoS ONE 2013; 8: e64709.
    • (2013) PLoS ONE , vol.8 , pp. e64709
    • Zhang, S.H.1    Wang, C.J.2    Shi, L.3    Li, X.H.4    Zhou, J.5    Song, L.B.6
  • 39
    • 79960575675 scopus 로고    scopus 로고
    • The forkhead transcription factor Foxc2 promotes osteoblastogenesis via up-regulation of integrin beta1 expression
    • Park SJ, Gadi J, Cho KW, Kim KJ, Kim SH, Jung HS et al. The forkhead transcription factor Foxc2 promotes osteoblastogenesis via up-regulation of integrin beta1 expression. Bone 2011; 49: 428-438.
    • (2011) Bone , vol.49 , pp. 428-438
    • Park, S.J.1    Gadi, J.2    Cho, K.W.3    Kim, K.J.4    Kim, S.H.5    Jung, H.S.6
  • 40
    • 33745685884 scopus 로고    scopus 로고
    • Bmi-1 is a novel molecular marker of nasopharyngeal carcinoma progression and immortalizes primary human nasopharyngeal epithelial cells
    • Song LB, Zeng MS, Liao WT, Zhang L, Mo HY, Liu WL et al. Bmi-1 is a novel molecular marker of nasopharyngeal carcinoma progression and immortalizes primary human nasopharyngeal epithelial cells. Cancer Res 2006; 66: 6225-6232.
    • (2006) Cancer Res , vol.66 , pp. 6225-6232
    • Song, L.B.1    Zeng, M.S.2    Liao, W.T.3    Zhang, L.4    Mo, H.Y.5    Liu, W.L.6
  • 41
    • 79957901659 scopus 로고    scopus 로고
    • HOXB7 as a prognostic factor and mediator of colorectal cancer progression
    • Liao WT, Jiang D, Yuan J, Cui YM, Shi XW, Chen CM et al. HOXB7 as a prognostic factor and mediator of colorectal cancer progression. Clin Cancer Res 2011; 17: 3569-3578.
    • (2011) Clin Cancer Res , vol.17 , pp. 3569-3578
    • Liao, W.T.1    Jiang, D.2    Yuan, J.3    Cui, Y.M.4    Shi, X.W.5    Chen, C.M.6
  • 42
    • 84866242179 scopus 로고    scopus 로고
    • The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions
    • Shibue T, Brooks MW, Inan MF, Reinhardt F, Weinberg RA. The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions. Cancer Discov 2012; 2: 706-721.
    • (2012) Cancer Discov , vol.2 , pp. 706-721
    • Shibue, T.1    Brooks, M.W.2    Inan, M.F.3    Reinhardt, F.4    Weinberg, R.A.5
  • 43
    • 80055118476 scopus 로고    scopus 로고
    • Orthotopic mouse model of colorectal cancer
    • Tseng W, Leong X, Engleman E. Orthotopic mouse model of colorectal cancer. J Vis Exp 2007; 10: 484.
    • (2007) J Vis Exp , vol.10 , pp. 484
    • Tseng, W.1    Leong, X.2    Engleman, E.3


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