Emergence of long-lived autoreactive plasma cells in the spleen of primary warm auto-immune hemolytic anemia patients treated with rituximab

Journal of Autoimmunity

Volumn 62, Issue , 2015, Pages 22-30

  Mahévas, Matthieu ^a,b,c   Michel, Marc ^b,c   Vingert, Benoit ^c   Moroch, Julien ^b   Boutboul, David ^d   Audia, Sylvain ^e   Cagnard, Nicolas ^f   Ripa, Julie ^c   Menard, Cédric ^g   Tarte, Karin ^g   Mégret, Jérôme ^h   Le Gallou, Simon ^a   Patin, Pauline ^a   Thai, Lan ^a   Galicier, Lionel ^d   Bonnotte, Bernard ^e   Godeau, Bertrand ^b   Noizat Pirenne, France ^c   Weill, Jean Claude ^a   Reynaud, Claude Agnès ^a  

^a INSTITUT NECKER ENFANTS MALADES   (France)

^b HENRI MONDOR HOSPITAL   (France)

^c UNIVERSITÉ PARIS EST CRÉTEIL   (France)

^d SAINT LOUIS HOSPITAL   (France)

^e DIJON UNIVERSITY HOSPITAL   (France)

^f UNIVERSITÉ PARIS DESCARTES   (France)

^g UNIVERSITÉ DE RENNES 1   (France)

^h INSERM   (France)

Author keywords

Anti CD20; Antibody secreting cells; B cell depletion; Long lived plasma cells; Warm autoimmune hemolytic anemia

Indexed keywords

B CELL ACTIVATING FACTOR; CORTICOSTEROID; HEMOGLOBIN; IMMUNOGLOBULIN G; RITUXIMAB; AUTOANTIBODY; IMMUNOLOGIC FACTOR;

ADULT; AGED; ANTIBODY SECRETING CELL; ARTICLE; AUTOIMMUNE HEMOLYTIC ANEMIA; BLOOD SAMPLING; CELL MATURATION; CELL SURVIVAL; CLINICAL ARTICLE; CORTICOSTEROID THERAPY; DISEASE DURATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; HUMORAL IMMUNE DEFICIENCY; IN VITRO STUDY; MALE; MIDDLE AGED; PLASMA CELL; PRIMARY WARM AUTOIMMUNE HEMOLYTIC ANEMIA; PRIORITY JOURNAL; SPLEEN; SPLEEN CELL; SPLENECTOMY; THROMBOCYTOPENIA; TREATMENT RESPONSE; VERY ELDERLY; YOUNG ADULT; ANEMIA, HEMOLYTIC, AUTOIMMUNE; AUTOIMMUNITY; B LYMPHOCYTE; BLOOD; ERYTHROCYTE; GENE EXPRESSION PROFILING; GENETICS; GERMINAL CENTER; IMMUNOLOGY; LYMPHOCYTE COUNT; METABOLISM; PATHOLOGY;

ADULT; AGED; ANEMIA, HEMOLYTIC, AUTOIMMUNE; AUTOANTIBODIES; AUTOIMMUNITY; B-CELL ACTIVATING FACTOR; B-LYMPHOCYTE SUBSETS; ERYTHROCYTES; FEMALE; GENE EXPRESSION PROFILING; GERMINAL CENTER; HUMANS; IMMUNOLOGIC FACTORS; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; PLASMA CELLS; RITUXIMAB; SPLEEN; SPLENECTOMY; YOUNG ADULT;

EID: 84939565560     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2015.05.006     Document Type: Article

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