Cellular Uptake Mechanism of Paclitaxel Nanocrystals Determined by Confocal Imaging and Kinetic Measurement

AAPS Journal

Volumn 17, Issue 5, 2015, Pages 1126-1134

  Chen, Yan ^a,b   Li, Tonglei ^b  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b PURDUE UNIVERSITY   (United States)

Author keywords

cellular uptake; confocal microscopy; nanocrystals; paclitaxel; pharmacokinetics

Indexed keywords

NANOCRYSTAL; PACLITAXEL; POLYMER; ANTINEOPLASTIC AGENT; NANOPARTICLE;

ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG COATING; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG SOLUBILITY; DRUG UPTAKE; ENDOCYTOSIS; HUMAN; HUMAN CELL; PARTICLE SIZE; QUANTITATIVE ANALYSIS; ZETA POTENTIAL; CHEMISTRY; DRUG DELIVERY SYSTEM; KB CELL LINE; PROCEDURES; SOLUBILITY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; DRUG DELIVERY SYSTEMS; HUMANS; KB CELLS; MICROSCOPY, CONFOCAL; NANOPARTICLES; PACLITAXEL; POLYMERS; SOLUBILITY;

EID: 84939563511     PISSN: None     EISSN: 15507416     Source Type: Journal    
DOI: 10.1208/s12248-015-9774-0     Document Type: Article

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