CD4+ T cells epigenetically modified by oxidative stress cause lupus-like autoimmunity in mice

Journal of Autoimmunity

Volumn 62, Issue , 2015, Pages 75-80

  Strickland, Faith M ^a   Li, YePeng ^a   Johnson, Kent ^a   Sun, Zhichao ^b   Richardson, Bruce C ^a,c  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

CD40L; CD70; KirL1; Systemic lupus erythematosus (SLE)

Indexed keywords

AZACITIDINE; CD40 LIGAND; CD70 ANTIGEN; DNA METHYLTRANSFERASE 1; HYDROGEN PEROXIDE; IMMUNOGLOBULIN G; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; OXIDIZING AGENT;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DEMETHYLATION; DISEASE SEVERITY; DNA METHYLATION; EPIGENETICS; FEMALE; GLOMERULONEPHRITIS; HEMATURIA; HISTOLOGY; HISTOPATHOLOGY; IN VITRO STUDY; KIDNEY PARENCHYMA; LYMPH NODE CELL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINURIA; SPLEEN CELL; SYSTEMIC LUPUS ERYTHEMATOSUS; ANIMAL; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; IMMUNOLOGY; METABOLISM; PATHOLOGY;

ANIMALS; AUTOIMMUNITY; CD4-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION; GLOMERULONEPHRITIS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE; OXIDANTS; OXIDATIVE STRESS;

EID: 84939562813     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2015.06.004     Document Type: Article

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